Psychosocial factors as strong predictors of mortality from cancer, ischaemic heart disease and stroke: The Yugoslav prospective study
Abstract
We investigated the relation of psychosocial risk factors to mortality in a prospective study of 1353 inhabitants of Crvenka, 619 of whom died between 1966 and 1976. All 38 lung cancer deaths occurred in those with high scores for rationality and antiemotionality (R/A), a factor related to suppression of aggression. Compared with lower R/A, high R/A was also associated with a relative risk of mortality of 29 for other cancer, 4.3 for ischaemic heart disease and 6.5 for stroke. Standardising for R/A reduced the smoking/lung cancer association, virtually eliminated the smoking/other cancer and smoking/heart disease relationships and reduced the association of heart disease with blood cholesterol, blood sugar and hypertension. Long lasting hopelessness was also independently associated with cancer as was anger with heart disease, though not so strongly as for R/A. Psychosocial variables are important predictors of mortality and decisively modify the effect of physical risk factors such as smoking.
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Suppression was first identified in a Yugoslavian cohort as predictive of all-cause and CVD death over 10 years, but was particularly predictive of cancer death in a study by Grossarth-Maticeck.
“Suppression was first identified in a Yugoslavian cohort as predictive of all-cause and CVD death over 10 years, but was particularly predictive of cancer death in a study by Grossarth-Maticeck [45].”
From Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine (2011) · cites this paper as [45]
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- Authors
- Grossarth-Maticek, R., Bastiaans, J., & Kanazir, D. T.
- Affiliations
- Leiden University (NL)
- Serbian Academy of Sciences and Arts (RS)
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 1985-01
- Volume
- 29
- Issue
- 2
- Pages
- 167-176
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W1986717123
- Cited by
- 173
- References
- 18
- Citations by year
- 2024: 4 · 2022: 2 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 1 · 2014: 1 · 2013: 4 · 2012: 2
- FWCI
- 4.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Social Sciences › Health › Health disparities and outcomes
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Keywords
- psychosocial risk factors, mortality, cancer mortality, ischemic heart disease, stroke, hopelessness, anger, smoking, serum cholesterol, hypertension, blood glucose
- MeSH terms
- Cerebral Infarction, Coronary Disease, Emotions, Female, Follow-Up Studies, Humans, Lung Neoplasms, Male, Middle Aged, Neoplasms, Personality, Prospective Studies, Psychophysiologic Disorders, Risk, Smoking, Yugoslavia
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