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Cited by 85Cardiac Health and Mental HealthHealth disparities and outcomesPersonality Traits and Psychology

Hostility May Explain the Association between Depressive Mood and Mortality: Evidence from the French GAZEL Cohort Study

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Lemogne, Cédric, Nabi, Hermann, Zins, Marie, Cordier, Sylvaine, Ducimetière, Pierre, Goldberg, Marcel, Consoli, Silla M.·2010·Psychotherapy and Psychosomatics
DOI 10.1159/000286961PMC PMC2876158
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Abstract

Background: Depressive mood is associated with mortality. Because personality has been found to be associated with depression and mortality as well, we aimed to test whether depressive mood could predict mortality when adjusting for several measures of personality. Methods: 20,625 employees of the French national gas and electricity companies gave consent to enter in the GAZEL cohort in 1989. Questionnaires were mailed in 1993 to assess depressive mood, type A behavior pattern, hostility, and the six personality types proposed by Grossarth-Maticek and Eysenck. Vital status and date of death were obtained annually for all participants. The association between psychological variables and mortality was measured by the Relative Index of Inequality (RII) computed through Cox regression. Results: 14,356 members of the GAZEL cohort (10,916 men, mean age: 49 years; 3,965 women, mean age: 46 years) completed the depressive mood scale and at least one personality scale. During a mean follow-up of 14.8 years, 687 participants had died. Depressive mood predicted mortality, even after adjustment for age, sex, education level, body mass index, alcohol consumption, and smoking [RII (95% CI) = 1.56 (1.16–2.11)]. However, this association was dramatically reduced (RII reduction: 78.9%) after further adjustment for cognitive hostility (i.e. hostile thoughts) [RII (95% CI) = 1.12 (0.80–1.57)]. Cognitive hostility was the only personality measure remaining associated with mortality after adjustment for depressive mood [RII (95% CI) = 1.97 (1.39–2.77)]. Conclusions: Cognitive hostility may either confound or mediate the association between depressive mood and mortality.

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Authors
Lemogne, C., Nabi, H., Zins, M., Cordier, S., Ducimetière, P., Goldberg, M., & Consoli, S. M.
Affiliations
  • Assistance Publique – Hôpitaux de Paris (FR)
  • Inserm (FR)
ORCID
Venue
Psychotherapy and Psychosomatics
Publisher
S. Karger AG
Published
2010
Volume
79
Issue
3
Pages
164-171
ISSN
  • 0033-3190 (ISSN-L)
  • 1423-0348
DOI
10.1159/000286961
PMC
PMC2876158
OpenAlex
W1993785396
Cited by
85
References
43
Citations by year
2023: 1 · 2022: 1 · 2021: 1 · 2020: 42 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 3 · 2015: 2 · 2014: 3 · 2013: 3 · 2012: 12
FWCI
5.05
Type
journal article
Language
en
Open access
Licence
Locations
  • Psychotherapy and Psychosomatics (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • HAL (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Social Sciences › Health › Health disparities and outcomes
  • Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
Keywords
depressive mood, mortality, hostility, personality, Type A behavior pattern, GAZEL cohort, confounding, mediation
MeSH terms
Accidents, Adult, Alcohol Drinking, Cause of Death, Coronary Disease, Depression, Depressive Disorder, Female, Hostility, Humans, Longitudinal Studies, Male, Middle Aged, Neoplasms, Personality Inventory, Psychometrics, Risk Factors, Self Concept, Smoking, Suicide, Type A Personality, Cohort Studies, Body Mass Index, Proportional Hazards Models

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