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Cited by 142Growth Hormone and Insulin-like Growth FactorsExercise and Physiological ResponsesHormonal and reproductive studies

Effects of progressive resistance training on growth hormone and testosterone levels in young and elderly subjects

Craig, B.W., Brown, R., Everhart, J.·1989·Mechanisms of Ageing and Development
DOI 10.1016/0047-6374(89)90099-7
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Abstract

We observed the response of serum growth hormone (GH) and testosterone (T) to a progressive resistance strength training program. Basal levels (after a 12-h fast) of GH and T were measured in young (23 years) and elderly (63 years) subjects before and after a 12-week training program. The response of GH and T to an acute bout of exercise was also measured. The exercise training, which involved all the major muscle groups, was conducted on Nautilus equipment and required 45-60 min for completion. The subjects completed three sets of lifts with 8-10 Reps/set. Blood was drawn from an anticubital vein, centrifuged (1169 g) for 15 min and the serum frozen for later analysis. The acute exercise blood samples were taken immediately before and after the exercise and at 15 min post-exercise during week 1 and 12. The hormone assay was carried out with radioimmunoassay kits for GH and T. The basal level of GH increased by 44.9% in the young and by only 3% in the elderly but neither change was significant. In response to a single exercise session GH levels in the young went from 0.85 +/- 0.13 to 4.19 +/- 1.45 ng/ml before training and from 1.45 +/- 0.11 to 8.61 +/- 2.55 after training. Each response was significant (P less than 0.05) as were the pre-post differences (P less than 0.001). In the elderly the response was not as great, values increasing from 1.00 +/- 0.09 to 2.92 +/- 0.65 ng/ml before training and from 1.50 +/- 0.06 to 3.43 +/- 0.64 ng/ml after training were recorded. These differences represented significant increases (P less than 0.05) but did not demonstrate pre- to post-changes. Basal levels of T decreased in both groups, but were not significant. The T response to an acute bout of exercise was not significant but did increase in both age groups. In conclusion, the data presented here indicate that strength training can induce growth hormone and testosterone release, regardless of age, but that the elderly response does not equal that of the young.

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Authors
Craig, B. W., Brown, R., & Everhart, J.
Affiliations
Ball State University (US)
Corresponding author
Craig, B.W.
ORCID
Craig, B.W.
Venue
Mechanisms of Ageing and Development
Publisher
Elsevier BV
Published
1989-08
Volume
49
Issue
2
Pages
159-169
ISSN
0047-6374 (ISSN-L)
DOI
10.1016/0047-6374(89)90099-7
OpenAlex
W2051857703
Cited by
142
References
23
Citations by year
2025: 2 · 2024: 1 · 2023: 3 · 2021: 7 · 2020: 5 · 2019: 6 · 2018: 3 · 2017: 2 · 2016: 7 · 2015: 6 · 2014: 4 · 2013: 5 · 2012: 4
FWCI
0.29
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Mechanisms of Ageing and Development (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Growth Hormone and Insulin-like Growth Factors
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
Keywords
progressive resistance training, resistance training, growth hormone, testosterone, aging, age differences, acute exercise response, serum hormone levels
MeSH terms
Adult, Aging, Humans, Male, Middle Aged, Physical Education and Training, Growth Hormone, Testosterone, Weight Lifting

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