Cited by 1,634Receptor Mechanisms and SignalingCytokine Signaling Pathways and InteractionsProtein Kinase Regulation and GTPase Signaling

Dimerization of cell surface receptors in signal transduction

Open access
Heldin, Carl-Henrik·1995·Cell

Integrity signals

Registry

Crossref · 10.1016/0092-8674(95)90404-2

Cites

114 of 114 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • EGFR is a member of the receptor tyrosine kinase family and a typical transmembrane receptor that initiates signaling cascades upon ligand-stimulated dimerization, thereby activating its tyrosine kinase and multiple downstream effectors.

    “Epidermal growth factor receptor (EGFR), a member of the receptor tyrosine kinase family, is a typical transmembrane receptor that initiates signaling cascades upon ligand-stimulated dimerization, thereby activating its tyrosine kinase and multiple downstream effectors.99–101”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Heldin, C.-H.
Affiliations
Ludwig Cancer Research (SE)
Corresponding author
Heldin, Carl-Henrik
Venue
Cell
Publisher
Elsevier BV
Published
1995-01
Volume
80
Issue
2
Pages
213-223
ISSN
0092-8674 (ISSN-L)
OpenAlex
W2008940139
Cited by
1,634
References
114
Citations by year
2026: 5 · 2025: 14 · 2024: 19 · 2023: 21 · 2022: 23 · 2021: 10 · 2020: 24 · 2019: 19 · 2018: 19 · 2017: 23 · 2016: 34 · 2015: 31 · 2014: 35 · 2013: 30 · 2012: 26
FWCI
14.44
Type
journal article
Language
en
Open access
Locations
  • Cell (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
  • Health Sciences › Medicine › Oncology › Cytokine Signaling Pathways and Interactions
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
Keywords
receptor dimerization, cell surface receptors, signal transduction, receptor oligomerization
MeSH terms
Animals, Humans, Phosphorylation, Protein-Tyrosine Kinases, Receptors, Antigen, Receptors, Cell Surface, Signal Transduction, Protein Serine-Threonine Kinases, Receptors, Cytokine, Receptors, Tumor Necrosis Factor, Receptor Protein-Tyrosine Kinases, Macromolecular Substances

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review