Anatomy of the CNS opioid systems
Open accessThe claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The three opioid receptor types have distinct patterns of expression throughout the brain, with significant inter-species variability.
“These three receptor types have distinct patterns of expression throughout the brain, and these patterns have significant inter-species variability (Khachaturian et al 1985; Robson et al 1985; Mansour et al 1987; Mansour et al 1988; Mansour et al 1994a; Mansour et al 1994b; Curran and Watson 1995; Resendez et al 2012).”
From The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction (2012) · cites this paper as Khachaturian et al 1985
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The rat brain in stereotaxic coordinates
Palkovits, M. (1983) · Neuropeptides · doi:10.1016/0143-4179(83)90049-5 · Cited by 28,959 · see citing works
The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585 · see citing works
Handbook of Chemical Neuroanatomy
Stern, C. D. (1986) · Neurochemistry International · doi:10.1016/0197-0186(86)90021-5 · Cited by 4,159 · see citing works
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Hughes, J., Smith, T. W., Kosterlitz, H. W., Fothergill, L. A., Morgan, B. A., & Morris, H. R. (1975) · Nature · doi:10.1038/258577a0 · Cited by 3,806 · see citing works
Handbook of Psychopharmacology
Iversen, L. L., Iversen, S. D., & Snyder, S. H. (1988) · Springer eBooks · doi:10.1007/978-1-4613-0933-8 · Cited by 2,755 · see citing works
Endogenous Opioids: Biology and Function
Akil, H., Watson, S. J., Young, E. A., Lewis, M. E., Khachaturian, H., & Walker, J. M. (1984) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.07.030184.001255 · Cited by 1,224 · see citing works
Self-citationImmunohistochemical localization of enkephalin in rat brain and spinal cord
Sar, M., Stumpf, W. E., Miller, R. J., Chang, K., & Cuatrecasas, P. (1978) · The Journal of Comparative Neurology · doi:10.1002/cne.901820103 · Cited by 822 · see citing works
Elde, R., Hökfelt, T. G. M., Johansson, O., & Terenius, L. Y. (1976) · Neuroscience · doi:10.1016/0306-4522(76)90063-4 · Cited by 774 · see citing works
The distribution of enkephalin-immunoreactive cell bodies in the rat central nervous system
Hökfelt, T. G. M., Elde, R. P., Johansson, O., Terenius, L. Y., & Stein, L. (1977) · Neuroscience Letters · doi:10.1016/0304-3940(77)90160-4 · Cited by 693 · see citing works
Dynorphin1–8 and dynorphin1–9 are ligands for the κ-subtype of opiate receptor
Corbett, A. D., Paterson, S. J., McKnight, A. T., Magnan, J., & Kosterlitz, H. W. (1982) · Nature · doi:10.1038/299079a0 · Cited by 447 · see citing works
Dynorphin and Vasopressin: Common Localization in Magnocellular Neurons
Watson, S. J., Akil, H., Fischli, W., D, A. G. M., Zimmerman, E. A., Nilaver, G., & Griedanus, T. B. V. W. (1982) · Science · doi:10.1126/science.6121376 · Cited by 415 · see citing works
Self-citationHormonal Proteins and Peptides
Li, C. H. (1979) · Elsevier eBooks · doi:10.1016/b978-0-12-447207-5.50001-x · Cited by 413 · see citing works
Evidence for two separate opiate peptide neuronal systems
Watson, S., Akil, H., Richard, C. W., & Barchas, J. (1978) · Nature · doi:10.1038/275226a0 · Cited by 410 · see citing works
Self-citationAdrenocorticotropin in Rat Brain: Immunocytochemical Localization in Cells and Axons
Watson, S. J., Richard, C. W., & Barchas, J. D. (1978) · Science · doi:10.1126/science.206967 · Cited by 336 · see citing works
Self-citationDynorphin immunocytochemistry in the rat central nervous system
Khachaturian, H., Watson, S. J., Lewis, M. E., Coy, D. H., D, A. G. M., & Akil, H. (1982) · Peptides · doi:10.1016/0196-9781(82)90063-8 · Cited by 320 · see citing works
Self-citationEnkephalin systems in diencephalon and brainstem of the rat
Khachaturian, H., Lewis, M. E., & Watson, S. J. (1983) · The Journal of Comparative Neurology · doi:10.1002/cne.902200305 · Cited by 286 · see citing works
Self-citationGee, C. E., Chen, C. C., Roberts, J. L., Thompson, R. C., & Watson, S. J. (1983) · Nature · doi:10.1038/306374a0 · Cited by 280 · see citing works
Self-citationComparison of the Distribution of Dynorphin Systems and Enkephalin Systems in Brain
Watson, S. J., Khachaturian, H., Akil, H., Coy, D. H., & D, A. G. M. (1982) · Science · doi:10.1126/science.6128790 · Cited by 279 · see citing works
Self-citationBloom, F. E., Battenberg, E., Rossier, J., LING, N. C., Leppäluoto, J., Vargo, T. M., & Guillemin, R. (1977) · Life Sciences · doi:10.1016/0024-3205(77)90126-6 · Cited by 273 · see citing works
Hypothalamic enkephalin neurones may regulate the neurohypophysis
Rossier, J., Battenberg, E., Pittman, Q. J., Bayón, A., Koda, L. Y., MILLER, R., Guillemin, R., & Bloom, F. E. (1979) · Nature · doi:10.1038/277653a0 · Cited by 259 · see citing works
Enkephalins co-exist with oxytocin and vasopressin in nerve terminals of rat neurohypophysis
Martin, R., & Voigt, K. H. (1981) · Nature · doi:10.1038/289502a0 · Cited by 233 · see citing works
Dynorphin-immunoreactive neurons in the central nervous system of the rat
Vincent, S. R., Hökfelt, T. G. M., Christensson, I., & Terenius, L. Y. (1982) · Neuroscience Letters · doi:10.1016/0304-3940(82)90249-x · Cited by 231 · see citing works
Immunohistochemical Localization of β-Lipotropic Hormone in the Pituitary Gland
Pelletier, G., Leclerc, R., Labrie, F., COTE, J., Chrétien, M., & Lis, M. (1977) · Endocrinology · doi:10.1210/endo-100-3-770 · Cited by 213 · see citing works
A dynorphinergic pathway of Leu-enkephalin production in rat substantia nigra
Zamir, N., Palkovits, M., Weber, E., Mezey, É., & Brownstein, M. (1984) · Nature · doi:10.1038/307643a0 · Cited by 196 · see citing works
Strategies for the biosynthesis of bioactive peptides
Mains, R. E., Eipper, B. A., Glembotski, C. C., & Dores, R. M. (1983) · Trends in Neurosciences · doi:10.1016/0166-2236(83)90100-5 · Cited by 176 · see citing works
α-MSH in rat brain: occurence within and outside of β-endorphin neurons
Watson, S. J., & Akil, H. (1980) · Brain Research · doi:10.1016/0006-8993(80)90849-5 · Cited by 168 · see citing works
Self-citationLewis, M. E., Mishkin, M., Bragin, E. O., Brown, R. M., Pert, C. B., & Pert, A. (1981) · Science · doi:10.1126/science.6258227 · Cited by 166 · see citing works
Self-citationTelencephalic enkephalinergic systems in the rat brain
Khachaturian, H., Lewis, M., Höllt, V., & Watson, S. J. (1983) · Journal of Neuroscience · doi:10.1523/jneurosci.03-04-00844.1983 · Cited by 147 · see citing works
Self-citationIn Situ Hybridization Histochemistry: A Technique for the Study of Gene Expression in Single Cells
Gee, C. E., & Roberts, J. L. (1983) · DNA · doi:10.1089/dna.1983.2.157 · Cited by 133 · see citing works
McGinty, J. F., van der Kooy, D., & Bloom, F. E. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-04-01104.1984 · Cited by 120 · see citing works
Naloxone augments electrophysiological signs of selective attention in man
Arnsten, A. F. T., Segal, D. S., Neville, H. J., Hillyard, S. A., Janowsky, D. S., Judd, L. L., & Bloom, F. E. (1983) · Nature · doi:10.1038/304725a0 · Cited by 109 · see citing works
ACTH-related peptide containing neurons within the medulla oblongata of the rat
Schwartzberg, D. G., & Nakane, P. K. (1983) · Brain Research · doi:10.1016/0006-8993(83)90746-1 · Cited by 106 · see citing works
Opiate receptor localization in rat cerebral cortex
Lewis, M. E., Pert, A., Pert, C. B., & Herkenham, M. A. (1983) · The Journal of Comparative Neurology · doi:10.1002/cne.902160310 · Cited by 100 · see citing works
Self-citationMicevych, P. E., & Elde, R. P. (1980) · The Journal of Comparative Neurology · doi:10.1002/cne.901900109 · Cited by 88 · see citing works
Peptide E and other proenkephalin-derived peptides are potent kappa opiate receptor agonists
Quirion, R., & Weiss, A. S. (1983) · Peptides · doi:10.1016/0196-9781(83)90047-5 · Cited by 78 · see citing works
Visualization and solubilization of rat brain opiate receptors with a ??? ligand selectivity pattern
Quirion, R., Bowen, W. D., Herkenham, M. A., & Pert, C. B. (1982) · Cellular and Molecular Neurobiology · doi:10.1007/bf00710853 · Cited by 54 · see citing works
Bevan, P. (1983) · Neuroscience Letters · doi:10.1016/0304-3940(83)90548-7 · Cited by 49 · see citing works
Visualization of opiate receptors and opioid peptides in sequential brain sections
Lewis, M. E., Khachaturian, H., & Watson, S. J. (1982) · Life Sciences · doi:10.1016/0024-3205(82)90378-2 · Cited by 37 · see citing works
Self-citationColocalization of proenkephalin peptides in rat brain neurons
Khachaturian, H., Lewis, M. E., & Watson, S. J. (1983) · Brain Research · doi:10.1016/0006-8993(83)90212-3 · Cited by 31 · see citing works
Self-citationOpioids: past, present and future
Cowan, A. (1984) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(84)90345-6 · Cited by 30 · see citing works
Hormonal Proteins and Peptides
(1981) · Elsevier eBooks · doi:10.1016/b978-0-12-447210-5.50001-x · Cited by 26 · see citing works
Lewis, M. E., Khachaturian, H., & Watson, S. J. (1983) · Life Sciences · doi:10.1016/0024-3205(83)90487-3 · Cited by 24 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 4
- Ll, C H (1981) in Hormonal Proteins and Peptutes (L1, C H , ed ), pp 2-30, Academic Press, New York
- Robson, L E , Paterson, S J and Koster- htz, H W (1983) in Handbook of Psycho- pharmacology (Iversen, L L, Iversen, S D and Snyder, S H, eds), pp 13--80, Plenum Press, New York 34
- Lewis, M E, Khachatunan, H and Watson, S J Pepttdes (m press) 37 Qmnon, R, Bowen, W, Herkenham, M and Pert, C B (1982) Cell Mol Neuroblol 2, 333-345 38
- Paxmos, G and Watson, C (1982) m The Rat Brain zn Stereotaxw Coordinates, Aca- demic Press
Cited by
Sorted by citations
Millan, M. J. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(02)00009-6 · Cited by 3,035 · see citing works
Prolactin: structure, function, and regulation of secretion
Freeman, M. E., Kanyicska, B., Lerant, A., & Nagy, G. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.4.1523 · Cited by 2,457 · see citing works
Drugs of abuse: anatomy, pharmacology and function of reward pathways
Koob, G. F. (1992) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(92)90060-j · Cited by 2,070 · see citing works
Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight
Kalra, S. P., Dube, M. G., Pu, S., Xu, B., Horváth, T. L., & Kalra, P. S. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.1.0357 · Cited by 1,556 · see citing works
Anatomy of CNS opioid receptors
Mansour, A., Khachaturian, H., Lewis, M. E., Akil, H., & Watson, S. J. (1988) · Trends in Neurosciences · doi:10.1016/0166-2236(88)90093-8 · Cited by 1,197 · see citing works
Self-citationA Role for Brain Stress Systems in Addiction
Koob, G. F. (2008) · Neuron · doi:10.1016/j.neuron.2008.06.012 · Cited by 1,056 · see citing works
The neurobiology and control of anxious states
Millan, M. J. (2003) · Progress in Neurobiology · doi:10.1016/s0301-0082(03)00087-x · Cited by 963 · see citing works
Sora, I., Takahashi, N., Funada, M., Ujike, H., Revay, R. S., Donovan, D. M., Miner, L. L., & Uhl, G. R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.4.1544 · Cited by 525 · see citing works
Herkenham, M. (1987) · Neuroscience · doi:10.1016/0306-4522(87)90268-5 · Cited by 520 · see citing works
Postexercise hypotension. Key features, mechanisms, and clinical significance.
Kenney, M., & Seals, D. R. (1993) · Hypertension · doi:10.1161/01.hyp.22.5.653 · Cited by 505 · see citing works
Simonin, F., Valverde, O., Smadja, C., Slowe, S., Kitchen, I., Dierich, A., Le Meur, M., Roques, B. P., Maldonado, R., & Kieffer, B. L. (1998) · The EMBO Journal · doi:10.1093/emboj/17.4.886 · Cited by 418 · see citing works
Neal, C. R., Mansour, A., Reinscheid, R. K., Nothacker, H., Civelli, O., & Watson, S. J. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990419)406:4 · Cited by 399 · see citing works
Self-citationKieffer, B. L. (1995) · Cellular and Molecular Neurobiology · doi:10.1007/bf02071128 · Cited by 389 · see citing works
Anand, K. J. S., & Carr, D. B. (1989) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(16)36722-0 · Cited by 382 · see citing works
Przewłocki, R., & Przewłocka, B. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01308-5 · Cited by 369 · see citing works
Neural substrates of opiate withdrawal
Koob, G. F., Maldonado, R. J., & Stinus, L. (1992) · Trends in Neurosciences · doi:10.1016/0166-2236(92)90171-4 · Cited by 356 · see citing works
Overexpression of Bcl-2 is neuroprotective after experimental brain injury in transgenic mice
Nakamura, M., Raghupathi, R., Merry, D. E., Scherbel, U., Saatman, K. E., & McIntosh, T. K. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19991004)412:4 · Cited by 81 · see citing works
Self-citationHypothalamic Proopiomelanocortin Neurons Are Glucose Responsive and Express KATPChannels
Ibrahim, N., Bosch, M. A., Smart, J. L., Qiu, J., Rubinstein, M., Rønnekleiv, O. K., Low, M. J., & Kelly, M. J. (2003) · Endocrinology · doi:10.1210/en.2002-221033 · Cited by 355 · see citing works
Dube, M. G., Kalra, S. P., & Kalra, P. S. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01824-7 · Cited by 335 · see citing works
κ-Opioid receptors and analgesia
Millan, M. J. (1990) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(90)90321-x · Cited by 324 · see citing works
Burkett, J. P., & Young, L. J. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2794-x · Cited by 307 · see citing works
“These three receptor types have distinct patterns of expression throughout the brain, and these patterns have significant interspecies variability (Khachaturian et al. 1985; Robson et al. 1985; Mansour et al. 1987, 1988, 1994a, b; Curran and Watson 1995; Resendez et al. 2012).”
Opioids, Reward and Addiction: An Encounter of Biology, Psychology, and Medicine
van Ree, J. M., Gerrits, M. A. F. M., & Vanderschuren, L. J. M. J. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01405-4 · Cited by 300 · see citing works
Hepatic Encephalopathy: An Update of Pathophysiologic Mechanisms
Hazell, A. S., & Butterworth, R. F. (1999) · Proceedings of The Society for Experimental Biology and Medicine · doi:10.1046/j.1525-1373.1999.d01-120.x · Cited by 299 · see citing works
Reiner, A. J., & Anderson, K. D. (1990) · Brain Research Reviews · doi:10.1016/0165-0173(90)90003-7 · Cited by 272 · see citing works
Pfaus, J. G., & Gorzalka, B. B. (1987) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(87)80002-7 · Cited by 271 · see citing works
The Endomorphin System and Its Evolving Neurophysiological Role
Fichna, J., Janecka, A. E., Costentin, J., & do-Rego, J.-C. (2007) · Pharmacological Reviews · doi:10.1124/pr.59.1.3 · Cited by 249 · see citing works
The opioid system in the gastrointestinal tract
Sternini, C., Patierno, S., Selmer, I.-S., & Kirchgessner, A. L. (2004) · Neurogastroenterology & Motility · doi:10.1111/j.1743-3150.2004.00553.x · Cited by 242 · see citing works
Oswald, L. M., & Wand, G. S. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2004.02.008 · Cited by 233 · see citing works
Brain regulation of feeding behavior and food intake in fish
Lin, X., Volkoff, H., Narnaware, Y. K., Bernier, N. J., Peyon, P., & Peter, R. E. (2000) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/s1095-6433(00)00230-0 · Cited by 230 · see citing works
Enhanced Sensitivity of Pituitary βEndorphin to Ethanol in Subjects at High Risk of Alcoholism
Gianoulakis, C. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830030072011 · Cited by 224 · see citing works
Marijuana's interaction with brain reward systems: Update 1991
Gardner, E. L., & Lowinson, J. H. (1991) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(91)90365-9 · Cited by 197 · see citing works
Gianoulakis, C. (2001) · PubMed Central · Cited by 193 · see citing works
Anderson, K. D., & Reiner, A. J. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902950302 · Cited by 186 · see citing works
Romano, G. J., Harlan, R. E., Shivers, B. D., Howells, R., & Pfaff, D. W. (1988) · Molecular Endocrinology · doi:10.1210/mend-2-12-1320 · Cited by 178 · see citing works
Arterial hypertension is associated with hypalgesia in humans.
Ghione, S., Rosa, C., Mezzasalma, L., & Panattoni, E. (1988) · Hypertension · doi:10.1161/01.hyp.12.5.491 · Cited by 170 · see citing works
IMPLICATIONS OF ENDOGENOUS OPIOIDS AND DOPAMINE IN ALCOHOLISM: HUMAN AND BASIC SCIENCE STUDIES
Gianoulakis, C. (1996) · Alcohol and Alcoholism · doi:10.1093/oxfordjournals.alcalc.a008216 · Cited by 162 · see citing works
Progesterone Blockade of Estrogen Activation of μ-Opioid Receptors Regulates Reproductive Behavior
Sinchak, K., & Micevych, P. E. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-15-05723.2001 · Cited by 157 · see citing works
Heijna, M. H., Padt, M., Hogenboom, F., Portoghese, P. S., Mulder, A. H., & Schoffelmeer, A. N. M. (1990) · European Journal of Pharmacology · doi:10.1016/0014-2999(90)90088-n · Cited by 157 · see citing works
Selective sparing of NADPH‐diaphorase neurons in neonatal hypoxia‐ischemia
Ferriero, D. M., Arcavi, L., Sagar, S. M., McIntosh, T. K., & Simon, R. P. (1988) · Annals of Neurology · doi:10.1002/ana.410240512 · Cited by 152 · see citing works
Mansour, A., Lewis, M. E., Khachaturian, H., Akil, H., & Watson, S. J. (1986) · Brain Research · doi:10.1016/0006-8993(86)90601-3 · Cited by 151 · see citing works
Self-citationβ-endorphin in the immune system: a role at last?
Panerai, A. E., & Sacerdote, P. (1997) · Immunology Today · doi:10.1016/s0167-5699(97)01045-1 · Cited by 150 · see citing works
Prodynorphin Processing by Proprotein Convertase 2
Day, R. W., Lazure, C., Basak, A., Boudreault, A., Limperis, P., Dong, W., & Lindberg, I. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.2.829 · Cited by 148 · see citing works
Opioid and anti‐opioid peptides
Cesselin, F. (1995) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.1995.tb00517.x · Cited by 142 · see citing works
DiFeliceantonio, A. G., & Berridge, K. C. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.02.032 · Cited by 141 · see citing works
The Relationship between Cardiovascular and Pain Regulatory Systems
Zamir, N., & Maixner, W. (1986) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1986.tb14641.x · Cited by 139 · see citing works
Jarjour, S., Bai, L., & Gianoulakis, C. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2009.00924.x · Cited by 130 · see citing works
Central nervous system action of peptides to influence gastrointestinal motor function
Taché, Y., Garrick, T., & Raybould, H. E. (1990) · Gastroenterology · doi:10.1016/0016-5085(90)90849-v · Cited by 126 · see citing works
The distribution of proenkephalin‐derived peptides in the central nervous system of turtles
Reiner, A. J. (1987) · The Journal of Comparative Neurology · doi:10.1002/cne.902590106 · Cited by 126 · see citing works
Marchant, N. J., Densmore, V. S., & Osborne, P. B. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21464 · Cited by 123 · see citing works
The role of opioid-dopamine interactions in the induction and maintenance of ethanol consumption
Cowen, M. S., & Lawrence, A. J. (1999) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(99)00060-3 · Cited by 121 · see citing works
Opiate receptors in rat pituitary are confined to the neural lobe and are exclusively kappa
Herkenham, M. A., Rice, K. C., Jacobson, A. E., & Rothman, R. B. (1986) · Brain Research · doi:10.1016/0006-8993(86)91346-6 · Cited by 121 · see citing works
Distribution of mu, delta, and kappa opiate receptor types in the forebrain and midbrain of pigeons
Reiner, A. J., Brauth, S. E., Kitt, C. A., & Quirion, R. (1989) · The Journal of Comparative Neurology · doi:10.1002/cne.902800304 · Cited by 119 · see citing works
Piecing together the puzzle of acetaldehyde as a neuroactive agent
Correa, M., Salamone, J. D., Segovia, K. N., Pardo, M., Longoni, R., Spina, L., Peana, A. T., Vinci, S., & Acquas, E. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.07.009 · Cited by 118 · see citing works
Wagner, E. J., Rønnekleiv, O. K., Grandy, D. K., & Kelly, M. J. (1998) · Neuroendocrinology · doi:10.1159/000054301 · Cited by 112 · see citing works
Ramkumar, V., & El‐Fakahany, E. E. (1988) · European Journal of Pharmacology · doi:10.1016/0014-2999(88)90488-8 · Cited by 108 · see citing works
Brain opioids and autism: An updated analysis of possible linkages
Sahley, T. L., & Panksepp, J. (1987) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01495056 · Cited by 107 · see citing works
Neural basis of maternal behavior in the rat
Numan, M. J. (1988) · Psychoneuroendocrinology · doi:10.1016/0306-4530(88)90006-6 · Cited by 104 · see citing works
An Allelic Variation in the Human Prodynorphin Gene Promoter Alters Stimulus‐Induced Expression
Zimprich, A. A., Kraus, J., Wöltje, M., Mayer, P. E., Rauch, E., & Höllt, V. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.740472.x · Cited by 104 · see citing works
Photoactivatable Neuropeptides for Spatiotemporally Precise Delivery of Opioids in Neural Tissue
Banghart, M. R., & Sabatini, B. L. (2012) · Neuron · doi:10.1016/j.neuron.2011.11.016 · Cited by 102 · see citing works
The hyperphagic effect of nociceptin/orphanin FQ in rats.
Polidori, C., CARO, G. D., & Massi, M. (2000) · Peptides · doi:10.1016/s0196-9781(00)00243-6 · Cited by 102 · see citing works
Differential messenger RNA expression of prodynorphin and proenkephalin in the human brain
Hurd, Y. L. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00002-4 · Cited by 99 · see citing works
Distribution of natriuretic peptide precursor mRNAs in the rat brain
Langub, M. C., Watson, R. E., & Herman, J. P. (1995) · The Journal of Comparative Neurology · doi:10.1002/cne.903560205 · Cited by 96 · see citing works
Analyzing the evolution of the opioid/orphanin gene family
Dores, R. M., Lecaudé, S., Bauer, D., & Danielson, P. B. (2002) · Mass Spectrometry Reviews · doi:10.1002/mas.10029 · Cited by 96 · see citing works
Cerebrospinal fluid and plasma β-endorphin in combat veterans with post-traumatic stress disorder
Baker, D. G., West, S. A., Orth, D. N., Hill, K. K., Nicholson, W. E., Ekhator, N. N., Bruce, A. B., Wortman, M. D., Keck, P. E., & Geracioti, T. D. (1997) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(97)00053-x · Cited by 95 · see citing works
The Molecular Basis of Opioid Receptor Function
Simonds, W. F. (1988) · Endocrine Reviews · doi:10.1210/edrv-9-2-200 · Cited by 94 · see citing works
Marinelli, P. W., Bai, L., Quirion, R., & Gianoulakis, C. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000183008.62955.2e · Cited by 93 · see citing works
Hughes, A. M., Everitt, B. J., & Herbert, J. (1987) · Neuroscience · doi:10.1016/0306-4522(87)90181-3 · Cited by 93 · see citing works
The opioid system in alcohol and drug dependence: Family‐based association study
Xuei, X., Wetherill, L. F., Bierut, L. J., Dick, D. M., Nürnberger, J. I., Foroud, T., & Edenberg, H. J. (2007) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30531 · Cited by 91 · see citing works
Effects of taste stimulation on β-endorphin levels in rat cerebrospinal fluid and plasma
Yamamoto, T., Sako, N., & Maeda, S. (2000) · Physiology & Behavior · doi:10.1016/s0031-9384(99)00252-8 · Cited by 91 · see citing works
Curtis, A. L., Bello, N. T., & Valentino, R. J. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-13-j0001.2001 · Cited by 91 · see citing works
Opioid inhibition of rapid eye movement sleep by a specific mu receptor agonist
Cronin, A. J., Keifer, J. C., Baghdoyan, H. A., & Lydic, R. (1995) · British Journal of Anaesthesia · doi:10.1093/bja/74.2.188 · Cited by 90 · see citing works
Siuciak, J. A., Wong, V., Pearsall, D., Wiegand, S. J., & Lindsay, R. M. (1995) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1995.tb00670.x · Cited by 88 · see citing works
Drug dependence and the endogenous opioid system
Gerrits, M. A. F. M., Lesscher, H. B. M., & van Ree, J. M. (2003) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2003.08.003 · Cited by 82 · see citing works
Anatomical Distribution of Opioid Receptors in Mammalians: An Overview
Mansour, A., & Watson, S. J. (1993) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-77460-7_5 · Cited by 82 · see citing works
Self-citationScherrer, G., Befort, K., Contet, C., Becker, J. A. J., Matifas, A., & Kieffer, B. L. (2004) · European Journal of Neuroscience · doi:10.1111/j.0953-816x.2004.03339.x · Cited by 81 · see citing works
Kowalski, C., Micheau, J., Corder, R., Gaillard, R. C., & Conte‐Devolx, B. (1992) · Brain Research · doi:10.1016/0006-8993(92)90314-y · Cited by 81 · see citing works
Anderson, K. D., & Reiner, A. J. (1991) · The Journal of Comparative Neurology · doi:10.1002/cne.903030410 · Cited by 80 · see citing works
Social play alters regional brain opioid receptor binding in juvenile rats
Vanderschuren, L. J. M. J., Stein, E. A., Wiegant, V. M., & Van Ree, J. M. (1995) · Brain Research · doi:10.1016/0006-8993(95)00256-p · Cited by 88 · see citing works
The Many Possible Roles of Opioids and Related Peptides in Stress‐Induced Analgesiaa
Akil, H., Young, E. A., Walker, J. M., & Watson, S. J. (1986) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1986.tb14625.x · Cited by 77 · see citing works
Self-citationDistribution and possible origin of β-endorphin and ACTH in discrete brainstem nuclei of rats
Palkovits, M., & Eskay, R. L. (1987) · Neuropeptides · doi:10.1016/0143-4179(87)90051-5 · Cited by 77 · see citing works
Olive, M. F., Antón, B., Micevych, P. E., Evans, C. J., & Maidment, N. T. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-19-07471.1997 · Cited by 89 · see citing works
Lewis, J. W., Baldrighi, G., & Akil, H. (1987) · Brain Research · doi:10.1016/0006-8993(87)91193-0 · Cited by 75 · see citing works
McIntosh, T. K., Head, V., & Faden, A. (1987) · Brain Research · doi:10.1016/0006-8993(87)90505-1 · Cited by 78 · see citing works
Taki, K., Kaneko, T., & Mizuno, N. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00124-x · Cited by 74 · see citing works
Li, B.-H., Xu, B., Rowland, N. E., & Kalra, S. P. (1994) · Brain Research · doi:10.1016/0006-8993(94)91348-x · Cited by 74 · see citing works
Broad, K. D., Kendrick, K. M., SIRINATHSINGHJI, D. J. S., & Keverne, E. B. (1993) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1993.tb00544.x · Cited by 73 · see citing works
Genetics of alcoholism: Role of the endogenous opioid system
Gianoulakis, C., & de Waele, J. (1994) · Metabolic Brain Disease · doi:10.1007/bf01999765 · Cited by 70 · see citing works
Tsou, K., Khachaturian, H., Akil, H., & Watson, S. J. (1986) · Brain Research · doi:10.1016/0006-8993(86)90283-0 · Cited by 70 · see citing works
Self-citationInvolvement of μ opioid receptors in the amygdala in the control of feeding
Gosnell, B. A. (1988) · Neuropharmacology · doi:10.1016/0028-3908(88)90050-0 · Cited by 69 · see citing works
Selective activation of opioid receptors differentially affects lordosis behavior in female rats
Pfaus, J. G., & Gorzalka, B. B. (1987) · Peptides · doi:10.1016/0196-9781(87)90106-9 · Cited by 69 · see citing works
Reiner, A. J., Medina, L. M., & Haber, S. N. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00254-1 · Cited by 67 · see citing works
Possible Brain Opioid Involvement in Disrupted Social Intent and Language Development of Autism
Panksepp, J., & Sahley, T. L. (1987) · Springer eBooks · doi:10.1007/978-1-4899-1992-2_19 · Cited by 66 · see citing works
Dysregulation of dynorphins in Alzheimer disease
Yakovleva, T., Marinova, Z., Kuzmin, A., Seidah, N. G., Haroutunian, V., Terenius, L. Y., & Bakalkin, G. Y. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.07.002 · Cited by 65 · see citing works
Evans, C. J., Hammond, D. L., & Frederickson, R. C. A. (1988) · Humana Press eBooks · doi:10.1007/978-1-60761-990-1_2 · Cited by 66 · see citing works
The opioid peptides. A role in hypertension?
FEUERSTEIN, G. Z., & Sirén, A. (1987) · Hypertension · doi:10.1161/01.hyp.9.6.561 · Cited by 64 · see citing works
The Role of Opioid Receptor Subtypes in the Development of Behavioral Sensitization to Ethanol
Pastor, R., & Aragón, C. M. G. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300928 · Cited by 61 · see citing works
Volume transmission of beta-endorphin via the cerebrospinal fluid; a review
Veening, J., Gerrits, P., & Barendregt, H. (2012) · Fluids and Barriers of the CNS · doi:10.1186/2045-8118-9-16 · Cited by 61 · see citing works
β-endorphin in brain limbic structures as neurochemical correlate of psychic dependence on drugs
Sweep, F. C. G. J., Wiegant, V. M., Vry, J. D., & van Ree, J. M. (1989) · Life Sciences · doi:10.1016/0024-3205(89)90341-x · Cited by 61 · see citing works
de Waele, J., Kiianmaa, K., & Gianoulakis, C. (1994) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1994.tb01452.x · Cited by 60 · see citing works
Minireview: Characterization of Influence of Central Nociceptin/Orphanin FQ on Consummatory Behavior
Olszewski, P. K., & Levine, A. S. (2004) · Endocrinology · doi:10.1210/en.2004-0016 · Cited by 59 · see citing works
- Authors
- Khachaturian, H., Lewis, M. E., Schäfer, M. K.-H., & Watson, S. J.
- Affiliations
- Universität Ulm (DE)
- Venue
- Trends in Neurosciences
- Publisher
- Elsevier BV
- Published
- 1985-01
- Volume
- 8
- Pages
- 111-119
- ISSN
- 0166-2236 (ISSN-L)
- OpenAlex
- W2053051844
- Cited by
- 428
- References
- 42
- Citations by year
- 2023: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2018: 1 · 2016: 5 · 2014: 3 · 2013: 2 · 2012: 7
- FWCI
- 5.09
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Trends in Neurosciences (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Funders
- National Institute of Mental Health
- National Institute on Drug Abuse
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- endogenous opioids
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review