The DOI matches its Crossref record; 69 of the 69 references it cites were found in a registry or an index.
The impact of postsynaptic calcium on synaptic transmission — its role in long-term potentiation
Abstract
Recent studies have gone a long way to explain the steps involved in generating long-term potentiation (LTP). This review focuses on the triggering role of postsynaptic calcium, the sequence of events which might be initiated by calcium, and where the persistent change may ultimately occur during LTP.
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In the citing paper
“Importantly, this same depolarization in the absence of synaptic stimulation fails to induce LTP.”
From Synaptic memory and CaMKII (2023) · cites this paper as [41]
In the citing paper
“However, it is now known that LTP can be induced by just depolarizing the postsynaptic cell with current through the recording electrode combined with low-frequency synaptic stimulation (40, 41).”
From Synaptic memory and CaMKII (2023) · cites this paper as [41]
Citations
Cites
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Magnesium gates glutamate-activated channels in mouse central neurones
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Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones
Mayer, M. L., Westbrook, G. L., & Guthrie, P. B. (1984) · Nature · doi:10.1038/309261a0 · Cited by 2,941
Excitatory Amino Acid Transmitters
Watkins, J. C., & Evans, R. H. (1981) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.21.040181.001121 · Cited by 2,497
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NMDA receptors - their role in long-term potentiation
Collingridge, G. L., & Bliss, T. (1987) · Trends in Neurosciences · doi:10.1016/0166-2236(87)90175-5 · Cited by 1,178
Intracellular injections of EGTA block induction of hippocampal long-term potentiation
Lynch, G., Larson, J., Kelso, S., Barrionuevo, G., & Schottler, F. (1983) · Nature · doi:10.1038/305719a0 · Cited by 1,116
An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation
Malenka, R. C., Kauer, J. A., Perkel, D. J., Mauk, M. D., Kelly, P. T., Nicoll, R. A., & Waxham, M. N. (1989) · Nature · doi:10.1038/340554a0 · Cited by 1,025
Self-citationMayer, M. L., & Westbrook, G. L. (1987) · The Journal of Physiology · doi:10.1113/jphysiol.1987.sp016883 · Cited by 943
Research works printed but not linked: 12
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Cited by
Sorted by citations
A synaptic model of memory: long-term potentiation in the hippocampus
Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566
The Amygdaloid Complex: Anatomy and Physiology
SAH, P., FABER, E. S. L., LOPEZ DE ARMENTIA, M., & POWER, J. (2003) · Physiological Reviews · doi:10.1152/physrev.00002.2003 · Cited by 1,745
Pathophysiology and treatment of focal cerebral ischemia
Siesjö, B. K. (1992) · Journal of neurosurgery · doi:10.3171/jns.1992.77.2.0169 · Cited by 1,296
A Brief History of Long-Term Potentiation
Nicoll, R. A. (2017) · Neuron · doi:10.1016/j.neuron.2016.12.015 · Cited by 841
Self-citationMalinow, R., & Tsien, R. W. (1990) · Nature · doi:10.1038/346177a0 · Cited by 797
Metadata
- Authors
- Malenka, R. C., Kauer, J. A., Perkel, D. J., & Nicoll, R. A.
- Affiliations
- University of California, San Francisco (US)
- Stanford University (US)
- Corresponding author
- Nicoll, R.A.
- Venue
- Trends in Neurosciences
- Publisher
- Elsevier BV
- Published
- 1989-01
- Volume
- 12
- Issue
- 11
- Pages
- 444-450
- ISSN
- 0166-2236 (ISSN-L)
- OpenAlex
- W2072731296
- Cited by
- 275
- References
- 69
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 2 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 4 · 2018: 1 · 2017: 3 · 2016: 2 · 2015: 3 · 2014: 1 · 2013: 4 · 2012: 5
- FWCI
- 3.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Neurosciences (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- U.S. Public Health Service (N524205)
- National Institute of Mental Health (MH00437)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- postsynaptic calcium, synaptic transmission, long-term potentiation, synaptic plasticity
- MeSH terms
- Animals, Calcium, Synaptic Transmission, Synapses, Synaptic Membranes, Time Factors, Receptors, N-Methyl-D-Aspartate, Receptors, Neurotransmitter
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