Cited by 3,223Memory and Neural MechanismsMemory Processes and InfluencesCognitive Abilities and Testing

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A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

Ennaceur, A., Delacour, J.·1988·Behavioural Brain Research

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Abstract

In this paper we describe a new memory test in rats, based on the differential exploration of familiar and new objects. In a first trial (T1), rats are exposed to one or to two identical objects (samples) and in a second trial, to two dissimilar objects, a familiar (the sample) and a new one. For short intertrial intervals (approximately 1 min), most rats discriminate between the two objects in T2: they spend more time in exploring the new object than the familiar one. This test has several interesting characteristics: (1) it is similar to visual recognition tests widely used in subhuman primates, this allows interspecies comparisons; (2) it is entirely based on the spontaneous behavior of rats and can be considered as a 'pure' working-memory test completely free of reference memory component; (3) it does not involve primary reinforcement such as food or electric shocks, this makes it comparable to memory tests currently used in man.

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Statistical principles in experimental design.
Winer, B. J. (1962) · McGraw-Hill Book Company · doi:10.1037/11774-000 · Cited by 27,137
Untitled work
(1978) · UA Campus Repository (The University of Arizona) · Cited by 8,010
The hippocampus as a cognitive map
Passingham, R. E. (1979) · Neuroscience · doi:10.1016/0306-4522(79)90015-0 · Cited by 5,128
The Neuropsychology of Memory
Squire, L. R. (1984) · Springer eBooks · doi:10.1007/978-3-642-70094-1_32 · Cited by 2,130
Hippocampus, space, and memory
Olton, D. S., Becker, J. T., & Handelmann, G. E. (1979) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00062713 · Cited by 2,018
Statistical Principles in Experimental Design.
Geisser, S., & Winer, B. J. (1963) · Journal of the American Statistical Association · doi:10.2307/2283359 · Cited by 1,934
Neurobiology of the hippocampus
Rawlins, J. N. P. (1984) · Neuroscience · doi:10.1016/0306-4522(84)90113-1 · Cited by 1,097
Neurobiology of learning and memory
Delacour, J. (1985) · Neuropsychologia · doi:10.1016/0028-3932(85)90073-9 · Cited by 1,026
Self-citation
Neural mechanisms of learning and memory
Young, J. Z. (1977) · Endeavour · doi:10.1016/0160-9327(77)90013-8 · Cited by 862
Human memory and amnesia
Cermak, L. S. (1982) · Cited by 815

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Authors: Ennaceur, A., & Delacour, J.
Affiliations: Université Paris Diderot (FR)
Corresponding author: Ennaceur, A.
ORCID: Ennaceur, A.
Venue: Behavioural Brain Research
Publisher: Elsevier BV
Published: 1988-11
Volume: 31
Issue: 1
Pages: 47-59
ISSN: 0166-4328 (ISSN-L)
DOI: 10.1016/0166-4328(88)90157-x
OpenAlex: W2072441360
Cited by: 3,223
References: 46
Citations by year: 2026: 105 · 2025: 124 · 2024: 148 · 2023: 138 · 2022: 143 · 2021: 179 · 2020: 172 · 2019: 189 · 2018: 171 · 2017: 182 · 2016: 166 · 2015: 161 · 2014: 161 · 2013: 134 · 2012: 152
FWCI: 1.52
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Behavioural Brain Research (publishedVersion)
PubMed (publishedVersion)
Sunderland Repository (University of Sunderland) (acceptedVersion)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
Keywords: object recognition memory, rats, working memory, reference memory, visual recognition memory, cross-species comparison, spontaneous behavior
MeSH terms: Animals, Attention, Brain, Exploratory Behavior, Habituation, Psychophysiologic, Male, Memory, Orientation, Rats, Inbred Strains, Mental Recall, Retention, Psychology, Rats

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A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

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