The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data
Abstract
In this paper we describe a new memory test in rats, based on the differential exploration of familiar and new objects. In a first trial (T1), rats are exposed to one or to two identical objects (samples) and in a second trial, to two dissimilar objects, a familiar (the sample) and a new one. For short intertrial intervals (approximately 1 min), most rats discriminate between the two objects in T2: they spend more time in exploring the new object than the familiar one. This test has several interesting characteristics: (1) it is similar to visual recognition tests widely used in subhuman primates, this allows interspecies comparisons; (2) it is entirely based on the spontaneous behavior of rats and can be considered as a 'pure' working-memory test completely free of reference memory component; (3) it does not involve primary reinforcement such as food or electric shocks, this makes it comparable to memory tests currently used in man.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Studies have reported that rodents can retain object information for at least 24 hours after the exposure (Ennaceur and Delacour, 1988).”
From The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties (2020) · cites this paper as Ennaceur and Delacour, 1988
In the citing paper
“The difference between the duration of exploration of a novel versus familiar object can be taken as an indication for memory, by the argument that animals tend to explore novel objects more because they remember the familiar ones (Ennaceur and Delacour, 1988).”
From The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties (2020) · cites this paper as Ennaceur and Delacour, 1988
In the citing paper
“NOP performance is variably dependent upon the time interval between the learning and test trials (Ennaceur and Delacour, 1988).”
From The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties (2020) · cites this paper as Ennaceur and Delacour, 1988
Citations
Cites
Statistical principles in experimental design.
Winer, B. J. (1962) · McGraw-Hill Book Company · doi:10.1037/11774-000 · Cited by 27,137
(1978) · UA Campus Repository (The University of Arizona) · Cited by 8,010
The hippocampus as a cognitive map
Passingham, R. E. (1979) · Neuroscience · doi:10.1016/0306-4522(79)90015-0 · Cited by 5,128
Squire, L. R. (1984) · Springer eBooks · doi:10.1007/978-3-642-70094-1_32 · Cited by 2,130
Hippocampus, space, and memory
Olton, D. S., Becker, J. T., & Handelmann, G. E. (1979) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00062713 · Cited by 2,018
Statistical Principles in Experimental Design.
Geisser, S., & Winer, B. J. (1963) · Journal of the American Statistical Association · doi:10.2307/2283359 · Cited by 1,934
Neurobiology of the hippocampus
Rawlins, J. N. P. (1984) · Neuroscience · doi:10.1016/0306-4522(84)90113-1 · Cited by 1,097
Neurobiology of learning and memory
Delacour, J. (1985) · Neuropsychologia · doi:10.1016/0028-3932(85)90073-9 · Cited by 1,026
Self-citationNeural mechanisms of learning and memory
Young, J. Z. (1977) · Endeavour · doi:10.1016/0160-9327(77)90013-8 · Cited by 862
Cermak, L. S. (1982) · Cited by 815
Cited by
Sorted by citations
Items 1,001–1,037 of 1,037
Protective effect of walnut on d ‐galactose‐induced aging mouse model
Liu, J., Chen, D., Wang, Z., Chen, C., Ning, D., & Zhao, S. (2019) · Food Science & Nutrition · doi:10.1002/fsn3.907 · Cited by 46
Janhunen, S. K., Svärd, H., Talpos, J., Kumar, G., Steckler, T., Plath, N., Lerdrup, L., Ruby, T., Haman, M., Wyler, R., et al. (2015) · Psychopharmacology · doi:10.1007/s00213-015-3954-6 · Cited by 43
Beer, Z., Vavra, P., Atucha, E., Rentzing, K., Heinze, H.-J., & Sauvage, M. M. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2006100 · Cited by 44
Verma, R., Harris, N. M., Friedler, B. D., Crapser, J., Patel, A. R., Venna, V., & McCullough, L. D. (2016) · Scientific Reports · doi:10.1038/srep25176 · Cited by 43
MGlu5 antagonism impairs exploration and memory of spatial and non-spatial stimuli in rats
Christoffersen, G. R. J., Simonyi, A., Schachtman, T. R., Clausen, B., Clement, D., Bjerre, V. K., Mark, L. T., Reinholdt, M., Schmith-Rasmussen, K., & Zink, L. V. B. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.03.032 · Cited by 42
Optogenetic stimulation of prefrontal glutamatergic neurons enhances recognition memory
Benn, A., Barker, G. R. I., Stuart, S. A., Roloff, E. V. L., Teschemacher, A. G., Warburton, E. C., & Robinson, E. S. J. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.2933-15.2016 · Cited by 42
de Souza Silva, M. A., Huston, J. P., Wang, A.-L., Petri, D., & Chao, O. Y.-H. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhv112 · Cited by 41
Impairments of exploration and memory after systemic or prelimbic D1-receptor antagonism in rats
Clausen, B., Schachtman, T. R., Mark, L. T., Reinholdt, M., & Christoffersen, G. R. J. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.03.069 · Cited by 41
Reardon, A. J. F., Karathra, J., Ribbenstedt, A., Benskin, J. P., MacDonald, A. M., Kinniburgh, D. W., Hamilton, T. J., Fouad, K., & Martin, J. W. (2019) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.9b00192 · Cited by 40
Papp, M., Gruca, P., Lason-Tyburkiewicz, M., Litwa, E., Niemczyk, M., Tota-Glowczyk, K., & Willner, P. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4651-4 · Cited by 40
Chao, O. Y.-H., Pum, M. E., & Huston, J. P. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.01.003 · Cited by 39
De Bundel, D., Femenía, T., DuPont, C. M., Konradsson-Geuken, Å., Feltmann, K., Schilström, B., & Lindskog, M. (2013) · International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713000370 · Cited by 37
Chen, M., Huang, T., Kuo, Y., Yu, L., Chen, H., & Jen, C. J. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2012.241125 · Cited by 37
Hsieh, M.-H., Meng, W.-Y., Liao, W.-C., Weng, J.-C., Li, H.-H., Su, H.-L., Lin, C.-L., Hung, C.-S., & Ho, Y.-J. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.05.015 · Cited by 35
Cucinotta, F. A., & Cacao, E. (2020) · Life Sciences in Space Research · doi:10.1016/j.lssr.2019.10.004 · Cited by 34
Pezze, M. A., Marshall, H. J., Fone, K. C., & Cassaday, H. J. (2017) · Learning & Memory · doi:10.1101/lm.044784.116 · Cited by 35
Kim, J. M., Kim, D. H., Lee, Y., Park, S. J., & Ryu, J. H. (2014) · Brain Research · doi:10.1016/j.brainres.2014.01.024 · Cited by 35
Roman, E., & Karlsson, O. (2013) · Upsala Journal of Medical Sciences · doi:10.3109/03009734.2013.821191 · Cited by 34
CA1 inactivation impairs episodic-like memory in rats
Drieskens, D. C., Neves, L. R., Pugliane, K. C., de Souza, I. B. M. B., Lima, Á. D. C., Salvadori, M. G. D. S. S., Ribeiro, A. M., Silva, R. H., & Barbosa, F. F. (2017) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2017.08.008 · Cited by 31
Spaced initial stimulus familiarization enhances novelty preference in Long-Evans rats
Anderson, M. J., Jablonski, S. A., & Klimas, D. B. (2008) · Behavioural Processes · doi:10.1016/j.beproc.2008.02.005 · Cited by 30
Stoiljkovic, M., Leventhal, L., Chen, A., Chen, T., Driscoll, R., Flood, D., Hodgdon, H., Hurst, R., Nagy, D., Piser, T., et al. (2015) · Biochemical Pharmacology · doi:10.1016/j.bcp.2015.07.006 · Cited by 29
Seemiller, L. R., & Gould, T. J. (2020) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2020.107234 · Cited by 23
Chao, O. Y., Nikolaus, S., Huston, J. P., & de Souza Silva, M. A. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2014.06.009 · Cited by 24
de Bruin, N. M. W. J., van Loevezijn, A., Wicke, K. M., de Haan, M., Venhorst, J., Lange, J. H. M., de Groote, L., van der Neut, M. A. W., Prickaerts, J., Andriambeloson, E., et al. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.06.020 · Cited by 22
Kinnavane, L., Amin, E., Horne, M., & Aggleton, J. P. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12740 · Cited by 21
Iwamura, E., Yamada, K., & Ichitani, Y. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.03.048 · Cited by 20
Olarte-Sánchez, C. M., Kinnavane, L., Amin, E., & Aggleton, J. P. (2014) · Behavioral Neuroscience · doi:10.1037/a0037055 · Cited by 18
Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model
Reinitz, F., Chen, E. Y., Nicolis di Robilant, B., Chuluun, B., Antony, J., Jones, R. C., Gubbi, N., Lee, K., Ho, W. H. D., Kolluru, S. S., et al. (2022) · eLife · doi:10.7554/elife.66037 · Cited by 18
Location and temporal memory of objects declines in aged marmosets (Callithrix jacchus)
De Castro, V., & Girard, P. (2021) · Scientific Reports · doi:10.1038/s41598-021-88357-7 · Cited by 17
Belblidia, H., Abdelouadoud, A., Jozet-Alves, C., Dumas, H., Freret, T., Leger, M., & Schumann-Bard, P. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.02.043 · Cited by 17
Social behavior in prepubertal neurexin 1α deficient rats: A model of neurodevelopmental disorders.
Kight, K. E., Argue, K. J., Bumgardner, J. G., Bardhi, K., Waddell, J., & McCarthy, M. M. (2021) · Behavioral Neuroscience · doi:10.1037/bne0000482 · Cited by 17
McLean, S. L., Harte, M. K., Neill, J. C., & Young, A. M. (2017) · Journal of Psychopharmacology · doi:10.1177/0269881117704988 · Cited by 16
Tam, S. K. E., Robinson, J., Jennings, D. J., & Bonardi, C. (2014) · Journal of Experimental Psychology Animal Learning and Cognition · doi:10.1037/xan0000003 · Cited by 15
O'Connor, S. M., Sleebs, B. E., Street, I. P., Flynn, B. L., Baell, J. B., Coles, C., Quazi, N., Paul, D., Poiraud, E., Huyard, B., et al. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.109836 · Cited by 15
Neugebauer, N. M., Miyauchi, M., Sato, T., Tadano, J., Akal, H., Ardehali, H., & Meltzer, H. Y. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.12.033 · Cited by 7
Tang, Y.-F., Duan, Y.-J., Ge, R.-D., Lu, X., Gao, B.-Y., Guo, J.-W., & Jiang, S. (2022) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2201005 · Cited by 5
A temporal context repetition effect in rats during a novel object recognition memory task
Manns, J. R., Galloway, C. R., & Sederberg, P. B. (2015) · Animal Cognition · doi:10.1007/s10071-015-0871-3 · Cited by 4
Metadata
- Authors
- Ennaceur, A., & Delacour, J.
- Affiliations
- Université Paris Diderot (FR)
- Corresponding author
- Ennaceur, A.
- ORCID
- Ennaceur, A.
- Venue
- Behavioural Brain Research
- Publisher
- Elsevier BV
- Published
- 1988-11
- Volume
- 31
- Issue
- 1
- Pages
- 47-59
- ISSN
- 0166-4328 (ISSN-L)
- OpenAlex
- W2072441360
- Cited by
- 3,223
- References
- 46
- Citations by year
- 2026: 105 · 2025: 124 · 2024: 148 · 2023: 138 · 2022: 143 · 2021: 179 · 2020: 172 · 2019: 189 · 2018: 171 · 2017: 182 · 2016: 166 · 2015: 161 · 2014: 161 · 2013: 134 · 2012: 152
- FWCI
- 1.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behavioural Brain Research (publishedVersion)
- PubMed (publishedVersion)
- Sunderland Repository (University of Sunderland) (acceptedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Keywords
- object recognition memory, rats, working memory, reference memory, visual recognition memory, cross-species comparison, spontaneous behavior
- MeSH terms
- Animals, Attention, Brain, Exploratory Behavior, Habituation, Psychophysiologic, Male, Memory, Orientation, Rats, Inbred Strains, Mental Recall, Retention, Psychology, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
