Cited by 127Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on BehaviorMemory and Neural Mechanisms

The DOI matches its Crossref record; 75 of the 76 references it cites were found in a registry or an index.

Efferent connections of the hypothalamic “aggression area” in the rat

Roeling, T.A.P., Veening, J.G., Kruk, M.R., Peters, J.P.W., Vermelis, M.E.J., Nieuwenhuys, R.·1994·Neuroscience

DOI 10.1016/0306-4522(94)90302-6

Open this paper in CoChat — free account

Abstract

The efferent connections of the hypothalamic area of the rat, where attack behaviour can be elicited by electrical stimulation, were studied using iontophoretic injections of Phaseolus vulgaris-leucoagglutinin. Specificity for the hypothalamic "attack area" was investigated by comparison with efferents of hypothalamic sites outside the attack area. The hypothalamic attack area consists of the intermediate hypothalamic area and the ventrolateral pole of the ventromedial hypothalamic nucleus. Fibres from the hypothalamic attack area, as well as fibres from several other hypothalamic sites, form diffuse fibre "streams" running rostrally or caudally. Many varicosities that are found on the fibres suggest, that these fibres are capable of influencing many brain sites along their way. Projection sites were found throughout the brain. In the comparison between attack area efferents and controls, many overlapping brain sites were found. Hypothalamic efferents preferentially originating in the largest part of the attack area, i.e. the intermediate hypothalamic area, were found in the mediodorsal and parataenial thalamic nuclei. Within the septum, a spatial organization of hypothalamic innervation was found. Fibres from the attack area formed specialized "pericellular baskets" in the dorsolateral aspect of the intermediate part of the lateral septal nucleus. Fibres from other hypothalamic sites were found in other septal areas and did not form these septal baskets. Within the mesencephalic central gray, fibres from the attack area were found specifically in the dorsal part and dorsal aspect of the lateral part of the central gray. Physiological and pharmacological studies have shown that several brain sites are involved in different aspects of aggressive behaviour. Some of these areas, as for instance the dorsomedial thalamic nucleus, septum and central gray, are innervated by efferents from the hypothalamic attack area, whereas other sites, like ventral premammillary nucleus and ventral tegmental area, are not. It is concluded from the present findings, that a number of brain sites, that are known to be involved in agonistic behaviour, receive hypothalamic information preferentially from the hypothalamic attack area through diffusely arranged varicose fibres. The function of each connection in the regulation of specific behaviours remains to be further investigated.

Integrity signals

Registry

Crossref · 10.1016/0306-4522(94)90302-6

Cites

75 of 75 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585
The Human Central Nervous System
Nieuwenhuys, R., Voogd, J., & van Huijzen, C. (2008) · doi:10.1007/978-3-540-34686-9 · Cited by 1,262
Self-citation
An anterograde neuroanatomical tracing method that shows the detailed morphology of neurons, their axons and terminals: Immunohistochemical localization of an axonally transported plant lectin, Phaseolus vulgaris-leucoagglutinin (PHA-L)
Gerfen, C. R., & Sawchenko, P. E. (1984) · Brain Research · doi:10.1016/0006-8993(84)90940-5 · Cited by 1,205
Organization of the afferent connections of the mediodorsal thalamic nucleus in the rat, related to the mediodorsal-prefrontal topography
Groenewegen, H. J. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90339-9 · Cited by 732
Chemoarchitecture of the Brain
Nieuwenhuys, R. (1985) · Springer eBooks · doi:10.1007/978-3-642-70426-0 · Cited by 500
Self-citation
The Human Central Nervous System
Nieuwenhuys, R., Voogd, J., & van Huijzen, C. (1988) · Springer eBooks · doi:10.1007/978-3-662-10343-2 · Cited by 477
Self-citation
Localization and pharmacological characterization of high affinity binding sites for vasopressin and oxytocin in the rat brain by light microscopic autoradiography
Tribollet, E., Barberis, C., Jard, S., Dubois-Dauphin, M., & Dreifuss, J. J. (1988) · Brain Research · doi:10.1016/0006-8993(88)91437-0 · Cited by 442
Efferent connections of the septal area in the rat: An analysis utilizing retrograde and anterograde transport methods
Meibach, R. C., & Siegel, A. (1977) · Brain Research · doi:10.1016/0006-8993(77)90088-9 · Cited by 438
Chemoarchitecture of the brain
(1987) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/0300-9629(87)90305-7 · Cited by 416
Some anatomical observations on the projections from the hypothalamus to brainstem and spinal cord: An HRP and autoradiographic tracing study in the cat
Holstege, G. (1987) · The Journal of Comparative Neurology · doi:10.1002/cne.902600109 · Cited by 366

Show all 76 references

Research works printed but not linked: 2

Millhouse, 1979, A Golgi anatomy of the rodent hypothalamus, Vol. 1, 221
Veening, 1991, Topography of hypothalamic projections to the periaqueductal grey (PAG) in the rat: a PHA-L study, Soc. Neurosci. Abstr., 17, 486.6

Sorted by citations

The Medial Extended Amygdala in Male Reproductive Behavior A Node in the Mammalian Social Behavior Network
NEWMAN, S. W. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09271.x · Cited by 1,189
Functional identification of an aggression locus in the mouse hypothalamus
Lin, D., Boyle, M. P., Dollar, P., Lee, H., Lein, E. S., Perona, P., & Anderson, D. J. (2011) · Nature · doi:10.1038/nature09736 · Cited by 914
Connections of the rat lateral septal complex 1Published on the World Wide Web on 2 June 1997. 1
Risold, P. Y., & Swanson, L. W. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00009-x · Cited by 671
Parallel, Redundant Circuit Organization for Homeostatic Control of Feeding Behavior
Betley, J. N., Cao, Z. F. H., Ritola, K., & Sternson, S. M. (2013) · Cell · doi:10.1016/j.cell.2013.11.002 · Cited by 591
Regulation of affect by the lateral septum: implications for neuropsychiatry
Sheehan, T. P., Chambers, R. A., & Russell, D. S. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.04.009 · Cited by 514
The medial hypothalamic defensive system: Hodological organization and functional implications
Canteras, N. S. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00685-2 · Cited by 463
Molecular Cloning and Functional Identification of Mouse Vesicular Glutamate Transporter 3 and Its Expression in Subsets of Novel Excitatory Neurons
Schäfer, M. K.-H., Varoqui, H., Defamie, N., Weihe, E., & Erickson, J. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206738200 · Cited by 410
Neuropharmacology of brain-stimulation-evoked aggression
Siegel, A., Roeling, T. A. P., Gregg, T. R., & Kruk, M. R. (1999) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(98)00040-2 · Cited by 381
Self-citation
The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y
Kask, A., Harro, J., von Hörsten, S., Redrobe, J. P., Dumont, Y., & Quirion, R. (2002) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(01)00066-5 · Cited by 358
Severe Reduction of Rat Defensive Behavior to a Predator by Discrete Hypothalamic Chemical Lesions
Canteras, N. S., Chiavegatto, S., do Valle, L. E. R., & Swanson, L. W. (1997) · Brain Research Bulletin · doi:10.1016/s0361-9230(97)00141-x · Cited by 274
Chemoarchitecture of the rat lateral septal nucleus 1Published on the World Wide Web on 2 June 1997. 1
Risold, P. Y., & Swanson, L. W. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00008-8 · Cited by 263
Multimodal analysis of cell types in a hypothalamic node controlling social behavior
Kim, D.-W., Yao, Z., Graybuck, L. T., Kim, T. K., Nguyen, T. N., Smith, K. A., Fong, O., Yi, L., Koulena, N., Pierson, N., et al. (2019) · Cell · doi:10.1016/j.cell.2019.09.020 · Cited by 259
Neural Connections of the Anterior Hypothalamus and Agonistic Behavior in Golden Hamsters
Delville, Y., Vries, G. J. D., & Ferris, C. F. (2000) · Brain Behavior and Evolution · doi:10.1159/000006642 · Cited by 251
Fast Positive Feedback Between the Adrenocortical Stress Response and a Brain Mechanism Involved in Aggressive Behavior.
Kruk, M. R., Halász, J., Meelis, W., & Haller, J. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.5.1062 · Cited by 212
Self-citation
The quartet theory of human emotions: An integrative and neurofunctional model
Koelsch, S., Jacobs, A. M., Menninghaus, W., Liebal, K., Klann-Delius, G., von Scheve, C., & Gebauer, G. (2015) · Physics of Life Reviews · doi:10.1016/j.plrev.2015.03.001 · Cited by 216
Interactions between the neural regulation of stress and aggression
Summers, C. H., & Winberg, S. (2006) · Journal of Experimental Biology · doi:10.1242/jeb.02565 · Cited by 202
Unravelling the neurophysiological basis of aggression in a fish model
Filby, A. L., Paull, G. C., Hickmore, T. F., & Tyler, C. R. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-498 · Cited by 206
Neuroanatomical Circuitry for Mammalian Maternal Behaviora
Numan, M., & Sheehan, T. P. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb51915.x · Cited by 194
Behavioral effects of α-MSH and MCH after central administration in the female rat
González, M. I., Vaziri, S. M., & Wilson, C. A. (1996) · Peptides · doi:10.1016/0196-9781(95)02092-6 · Cited by 193
Heat stress and poultry production: a comprehensive review
Oluwagbenga, E. M., & Fraley, G. S. (2023) · Poultry Science · doi:10.1016/j.psj.2023.103141 · Cited by 168
Monoamine-sensitive developmental periods impacting adult emotional and cognitive behaviors
Suri, D., Teixeira, C. M., Cagliostro, M. K. C., Mahadevia, D., & Ansorge, M. S. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2014.231 · Cited by 167
Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states
Picciotto, M. R., Lewis, A. S., van Schalkwyk, G. I., & Mineur, Y. S. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.12.028 · Cited by 157
The role of oxytocin in male and female reproductive behavior
Veening, J. G., A, T. R. D. J., Waldinger, M. D., Korte, S. M., & Olivier, B. (2014) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.07.045 · Cited by 156
Self-citation
Do similar neural systems subserve aggressive and sexual behaviour in male rats? Insights from c-Fos and pharmacological studies
Veening, J. G., Coolen, L. M., A, T. R. D. J., Joosten, H. W. J., de Boer, S. F., Koolhaas, J. M., & Olivier, B. (2005) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2005.09.041 · Cited by 156
Self-citation
Are periaqueductal gray and dorsal raphe the foundation of appetitive and aversive control? A comprehensive review
Silva, C., & McNaughton, N. (2019) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2019.02.001 · Cited by 166
Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility
Homberg, J. R., Pattij, T., Janssen, M. C. W., Ronken, E., de Boer, S. F., Schoffelmeer, A. N. M., & Cuppen, E. P. J. G. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05839.x · Cited by 151
Connectional architecture of a mouse hypothalamic circuit node controlling social behavior
Lo, L., Yao, S., Kim, D., Cetin, A. H., Harris, J. A., Zeng, H., Anderson, D. J., & Weissbourd, B. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1817503116 · Cited by 141
The neural circuitry of social homeostasis: Consequences of acute versus chronic social isolation
Lee, C. R., Chen, A., & Tye, K. M. (2021) · Cell · doi:10.1016/j.cell.2021.02.028 · Cited by 148
Chapter 33 The greater limbic system, the emotional motor system and the brain
Nieuwenhuys, R. (1996) · Progress in brain research · doi:10.1016/s0079-6123(08)61887-7 · Cited by 134
Self-citation
Optogenetics, Sex, and Violence in the Brain: Implications for Psychiatry
Anderson, D. J. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.11.012 · Cited by 129
Oxytocin-messages via the cerebrospinal fluid: Behavioral effects; a review
Veening, J. G., A, T. R. D. J., & Barendregt, H. P. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.05.004 · Cited by 129
Self-citation
Imaging the neural circuitry and chemical control of aggressive motivation
Ferris, C. F., Stolberg, T. L., Kulkarni, P. P., Murugavel, M., Blanchard, R. J., Blanchard, D. C., Febo, M., Brevard, M. E., & Simon, N. G. (2008) · BMC Neuroscience · doi:10.1186/1471-2202-9-111 · Cited by 124
The hypothalamus: cross-roads of endocrine and behavioural regulation in grooming and aggression
Kruk, M. R., Westphal, K. G. C., van Erp, A. M. M., van Asperen, J., Cave, B. J., Slater, E., de Koning, J., & Haller, J. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(98)00018-9 · Cited by 123
Self-citation
An insular view of the social decision-making network
Rogers-Carter, M. M., & Christianson, J. P. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.06.005 · Cited by 121
Glucocorticoid interaction with aggression in non-mammalian vertebrates: Reciprocal action
Summers, C. H., Watt, M. J., Ling, T. J., Forster, G. L., Carpenter, R. E., Korzan, W. J., Lukkes, J. L., & Øverli, Ø. (2005) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2005.09.059 · Cited by 106
Projections from the subfornical region of the lateral hypothalamic area
Goto, M., Canteras, N. S., Burns, G., & Swanson, L. W. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20764 · Cited by 95
Brain mechanisms of aggressive behavior: an updated review.
Adams, D. B. (2006) · Neuroscience and Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.09.004 · Cited by 97
Neurochemical characterization of hypothalamic neurons involved in attack behavior: Glutamatergic dominance and co-expression of thyrotropin-releasing hormone in a subset of glutamatergic neurons
Hrabovszky, E., Halász, J., Meelis, W., Kruk, M. R., Liposits, Z., & Haller, J. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.03.042 · Cited by 78
Self-citation
Brain mechanisms involved in predatory aggression are activated in a laboratory model of violent intra‐specific aggression
Tulogdi, A., Toth, M., Halasz, J., Mikics, E., Fuzesi, T., & Haller, J. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07429.x · Cited by 76
Hippocampal mossy fiber distributions and intermale aggression in seven inbred mouse strains
Guillot, P. V., Roubertoux, P. L., & Crusio, W. E. (1994) · Brain Research · doi:10.1016/0006-8993(94)90852-4 · Cited by 76
Lack of aggression and anxiolytic-like behavior in TNF receptor (TNF-R1 and TNF-R2) deficient mice
Patel, A., Siegel, A., & Zalcman, S. S. (2010) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2010.05.005 · Cited by 77
Ventral premammillary nucleus as a critical sensory relay to the maternal aggression network
Motta, S. C., Guimarães, C. C., Furigo, I. C., Sukikara, M. H., Baldo, M. V. C., Lonstein, J. S., & Canteras, N. S. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1305581110 · Cited by 75
Neural inputs of the hypothalamic "aggression area" in the rat.
Tóth, M., Fuzesi, T., Halasz, J., Tulogdi, Á., & Haller, J. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.05.050 · Cited by 70
Hypothalamic attack area-mediated activation of the forebrain in aggression
Hal??sz, J., Liposits, Z., Meelis, W., Kruk, M. R., & Haller, J. (2002) · Neuroreport · doi:10.1097/00001756-200207190-00010 · Cited by 71
Self-citation
The neurobiology of offensive aggression: Revealing a modular view
de Boer, S. F., Olivier, B., Veening, J., & Koolhaas, J. M. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.04.040 · Cited by 70
Self-citation
Activation of corticotropin-releasing factor receptor 2 in lateral septum negatively regulates maternal defense.
D'Anna‐Hernandez, K., & Gammie, S. C. (2009) · Behavioral Neuroscience · doi:10.1037/a0014987 · Cited by 64
Predominant information transfer from layer III pyramidal neurons to corticospinal neurons
Kaneko, T., Cho, R.-H., Li, Y.-Q., Nomura, S., & Mizuno, N. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20000717)423:1 · Cited by 59
Recent advances in understanding the role of the hypothalamic circuit during aggression
Falkner, A. L., & Lin, D. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00168 · Cited by 60
Adrenergic innervation of forebrain neurons that project to the paraventricular thalamic nucleus in the rat
Otake, K., Ruggiero, D. A., & Nakamura, Y. (1995) · Brain Research · doi:10.1016/0006-8993(95)00749-g · Cited by 60
Ictogenesis and symptomatogenesis of gelastic seizures in hypothalamic hamartomas: An ictal SPECT study
Kameyama, S., Masuda, H., & Murakami, H. (2010) · Epilepsia · doi:10.1111/j.1528-1167.2010.02739.x · Cited by 58
Unravelling cortico-hypothalamic pathways regulating unconditioned fear-induced antinociception and defensive behaviours
Falconi‐Sobrinho, L. L., dos Anjos‐Garcia, T., Elias-Filho, D. H., & Coimbra, N. C. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.10.001 · Cited by 57
Mammals
Voogd, J., Nieuwenhuys, R., van Dongen, P. A. M., & ten Donkelaar, H. J. (1998) · Springer eBooks · doi:10.1007/978-3-642-18262-4_22 · Cited by 46
Self-citation
Behavioral effects of neuropeptide E-I (NEI) in the female rat: interactions with α-MSH, MCH and dopamine
González, M. I., Baker, B. I., Hole, D. R., & Wilson, C. A. (1998) · Peptides · doi:10.1016/s0196-9781(98)00045-x · Cited by 45
Sexual Dimorphism of Inputs to the Lateral Habenula in Mice
Liu, X., Huang, H., Zhang, Y., Wang, L., & Wang, F. (2022) · Neuroscience Bulletin · doi:10.1007/s12264-022-00885-y · Cited by 44
Neurobiology of Aggression—Review of Recent Findings and Relationship with Alcohol and Trauma
Fritz, M., Soravia, S.-M., Dudeck, M., Malli, L., & Fakhoury, M. (2023) · Biology · doi:10.3390/biology12030469 · Cited by 44
Mineralocorticoid receptor blockade during a rat’s first violent encounter inhibits its subsequent propensity for violence.
Kruk, M. R., Haller, J., Meelis, W., & de Kloet, E. R. (2013) · Behavioral Neuroscience · doi:10.1037/a0033553 · Cited by 41
Self-citation
The dopaminergic system and aggression in laying hens
Dennis, R. L., & Cheng, H. W. (2011) · Poultry Science · doi:10.3382/ps.2011-01513 · Cited by 40
Neural mechanisms of female sexual behavior in the rat; comparison with male ejaculatory control
Veening, J. G., Coolen, L. M., & Gerrits, P. O. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.11.025 · Cited by 38
Self-citation
Substance P neurotransmission and violent aggression: The role of tachykinin NK1 receptors in the hypothalamic attack area
Halász, J., Zelena, D., Tóth, M., Tulogdi, Á., Mikics, É., & Haller, J. (2009) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2009.03.050 · Cited by 39
Hypothalamic Attack: A Wonderful Artifact or a Useful Perspective on Escalation and Pathology in Aggression? A Viewpoint
Kruk, M. R. (2014) · Current topics in behavioral neurosciences · doi:10.1007/7854_2014_313 · Cited by 38
Self-citation
The role of lateral septal NK1 receptors in mediating anxiogenic effects induced by intracerebroventricular injection of substance P
Gavioli, E. C., Canteras, N. S., & de Lima, T. C. M. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(02)00054-2 · Cited by 37
Brainstem projections of neurons located in various subdivisions of the dorsolateral hypothalamic area – an anterograde tract-tracing study
Papp, R. S. (2014) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2014.00034 · Cited by 37
Cocaine treatment alters oxytocin receptor binding but not mRNA production in postpartum rat dams
Jarrett, T. M., McMurray, M. S., Walker, C. H., & Johns, J. M. (2006) · Neuropeptides · doi:10.1016/j.npep.2006.03.002 · Cited by 35
The benefits of magnetic resonance imaging methods to extend the knowledge of the anatomical organisation of the periaqueductal gray in mammals
Menant, O., Andersson, F., Zelena, D., & Chaillou, É. (2016) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2016.06.003 · Cited by 37
Septal projections to nucleus incertus in the rat: Bidirectional pathways for modulation of hippocampal function
Sánchez‐Pérez, A. M., Arnal-Vicente, I., dos Santos, F. N., Pereira, C. W., Mlili, N. E., Sanjuán, J., Ma, S., Gundlach, A. L., & Olucha-Bordonau, F. E. (2014) · The Journal of Comparative Neurology · doi:10.1002/cne.23687 · Cited by 31
Excitatory projections from the anterior hypothalamus to periaqueductal gray neurons that project to the medulla: a functional anatomical study
Semenenko, F. M., & Lumb, B. M. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00317-6 · Cited by 29
Participation of the Medial and Anterior Hypothalamus in the Modulation of Tonic Immobility in Guinea Pigs
Oliveira, L., Hoffmann, A., & Menescal-de-Oliveira, L. (1997) · Physiology & Behavior · doi:10.1016/s0031-9384(97)00351-x · Cited by 28
Photoperiod alters central distribution of estrogen receptor α in brain regions that regulate aggression
Kramer, K. M., Simmons, J. L., & Freeman, D. A. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.11.002 · Cited by 28
Pattern of c-Fos expression induced by tail suspension test in the mouse brain
Hiraoka, K., Motomura, K., Yanagida, S., Ohashi, A., Ishisaka-Furuno, N., & Kanba, S. (2017) · Heliyon · doi:10.1016/j.heliyon.2017.e00316 · Cited by 26
TheFoxb1‐expressing neurons of the ventrolateral hypothalamic parvafox nucleus project to defensive circuits
Bilella, A., Álvarez-Bolado, G., & Celio, M. R. (2016) · The Journal of Comparative Neurology · doi:10.1002/cne.24057 · Cited by 24
In the ventral tegmental area picrotoxin blocks FGIN 1-27-induced increases in sexual behavior of rats and hamsters
Petralia, S. M., & Frye, C. A. (2004) · Psychopharmacology · doi:10.1007/s00213-004-2001-9 · Cited by 22
A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats
Narváez, M., Borroto‐Escuela, D. O., Santín, L. J., Millón, C., Gago, B., Flores‐Burgess, A., Barbancho, M. Á., de la Mora, M. P., Narváez, J. Á., Dı́az-Cabiale, Z., et al. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00119 · Cited by 22
Two parts of the nucleus prepositus hypoglossi project to two different subdivisions of the dorsolateral periaqueductal gray in cat
Klop, E. M., Mouton, L. J., Ehling, T., & Holstege, G. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20728 · Cited by 21
Effect of acute imipramine administration on the pattern of forced swim-induced c-Fos expression in the mouse brain
Yanagida, S., Motomura, K., Ohashi, A., Hiraoka, K., Miura, T., & Kanba, S. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.06.059 · Cited by 20
Y chromosomal effects on hippocampal mossy fiber distributions in mice selected for aggression
Hensbroek, R. A., Sluyter, F., Guillot, P. V., van Oortmerssen, G. A., & Crusio, W. E. (1995) · Brain Research · doi:10.1016/0006-8993(95)00270-z · Cited by 20
Pheromonal Signals Access the Medial Extended Amygdala
Newman, S. W. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50019-6 · Cited by 19
Large-Scale Gene Expression Profiling of Discrete Brain Regions: Potential, Limitations, and Application in Genetics of Aggressive Behavior
Feldker, D. E. M., de Kloet, E. R., Kruk, M. R., & Datson, N. A. (2003) · Behavior Genetics · doi:10.1023/a:1025726801047 · Cited by 19
Self-citation
Low-dose perinatal diethylstilbestrol exposure affected behaviors and hypothalamic estrogen receptor-α-positive cells in the mouse
Tanaka, M., Ohtani‐Kaneko, R., Yokosuka, M., & Watanabe, C. (2004) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2003.11.003 · Cited by 18
Structure and Organisation of Fibre Systems
Nieuwenhuys, R. (1998) · Springer eBooks · doi:10.1007/978-3-642-18262-4_3 · Cited by 15
Self-citation
Angry Rats and Scaredy Cats: Lessons from Competing Cognitive Homologies
Wiegman, I. (2016) · Biological Theory · doi:10.1007/s13752-016-0249-z · Cited by 12
Epileptic hypothalamic hamartomas impact of topography on clinical presentation and radiosurgical outcome
Hamdi, H., Ferrante, P., Spatola, G., Clawson, W. P., McGonigal, A., Daquin, G., Villeneuve, N., Laguitton, V., Bartoloméi, F., & Régis, J. M. (2021) · Epilepsy Research · doi:10.1016/j.eplepsyres.2021.106624 · Cited by 12
Pair Bond-Induced Affiliation and Aggression in Male Prairie Voles Elicit Distinct Functional Connectivity in the Social Decision-Making Network
Gossman, K. R., Dykstra, B., García, B. H., Swopes, A. P., Kimbrough, A., & Smith, A. S. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.748431 · Cited by 12
A Hypothalamic Perspective of Human Socioemotional Behavior
Carìa, A. (2023) · The Neuroscientist · doi:10.1177/10738584221149647 · Cited by 10
Functional diversity along the anteroposterior axis of the ventromedial hypothalamus
Gutiérrez‐Castellanos, N., Dias, I. C., Husain, B. F. A., & Lima, S. Q. (2024) · Journal of Neuroendocrinology · doi:10.1111/jne.13447 · Cited by 9
Defense and Aggression
Blanchard, D. C., Litvin, Y., Pentkowski, N. S., & Blanchard, R. J. (2009) · Wiley eBooks · doi:10.1002/9780470478509.neubb002049 · Cited by 9
Sexually dimorphic oxytocin receptor‐expressing ( OXTR ) neurons in the anteroventral periventricular nucleus ( AVPV ) in the postpartum female mouse are involved in maternal behavior
Sharma, K., Govar, A. A., Ghimire, B., Nishimori, K., Hammock, E. A. D., & Teruyama, R. (2023) · Journal of Neuroendocrinology · doi:10.1111/jne.13337 · Cited by 8
Hypothalamic resting-state functional connectivity and self-evaluated aggression in young adults
Yao, Y. J., Chen, Y., & Li, C.-S. R. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.01.045 · Cited by 7
Effects of serta and sertb knockout on aggression in zebrafish (Danio rerio)
Tea, M., Pan, Y. K., Lister, J. G. R., Perry, S. F., & Gilmour, K. M. (2024) · Journal of Comparative Physiology A · doi:10.1007/s00359-024-01693-7 · Cited by 6
Hypothalamic aggression area under serotonergic control in mouse-killing behaviour of rats
Ueda, S., Ishizuya‐Oka, A., Nishimura, A., Takeuchi, Y., & Yoshimoto, K. (1999) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145799001571 · Cited by 6
The sex ratio of a gilt’s birth litter can affect her fitness as a breeding female
Seyfang, J., Kirkwood, R. N., Tilbrook, A. J., & Ralph, C. R. (2018) · Animal Production Science · doi:10.1071/an17192 · Cited by 5
First evidence of neuronal connections between specific parts of the periaqueductal gray (PAG) and the rest of the brain in sheep: placing the sheep PAG in the circuit of emotion
Menant, O., Prima, M., Morisse, M., Cornilleau, F., Moussu, C., Gautier, A., Blanchon, H., Meurisse, M., Delagrange, P., Tillet, Y., et al. (2018) · Brain Structure and Function · doi:10.1007/s00429-018-1689-y · Cited by 5
Vasopressin: Roles in Modulating Social Behaviors
Williams, S. K., & Cymerblit‐Sabba, A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803592-4.00057-2 · Cited by 5
Diencephalon: Hypothalamus
(2007) · Springer eBooks · doi:10.1007/978-3-540-34686-9_10 · Cited by 5
Greater Limbic System
(2007) · Springer eBooks · doi:10.1007/978-3-540-34686-9_23 · Cited by 4
The Hypothalamus and Hypothalamohypophysial Systems
ten Donkelaar, H. J. (2011) · Springer eBooks · doi:10.1007/978-3-642-19134-3_13 · Cited by 4
Aggression and Defense, Neurohormonal Mechanisms of
Blanchard, R. J., Markham, C. M., & Blanchard, D. C. (2005) · Wiley eBooks · doi:10.1002/0470018860.s00440 · Cited by 3
Modeling Anger-Like Responses in Animals: Denial of Food in Sight
Subhedar, N. K., Dudhabhate, B. B., & Kokare, D. M. (2023) · Springer eBooks · doi:10.1007/978-3-031-31547-3_143 · Cited by 2
Fos expression in the periaqueductal gray, but not the ventromedial hypothalamus, is correlated with psychosocial stress-induced cocaine-seeking behavior in rats
Hinds, N. M., Wojtas, I. D., Pulley, D. M., McDonald, S. J., Spencer, C. D., Sudarikov, M., Hubbard, N. E., Kulick-Soper, C. M., de Guzman, S., Hayden, S., et al. (2025) · Addiction Neuroscience · doi:10.1016/j.addicn.2025.100217 · Cited by 3
Sensible or senseless violence from the brain
Kruk, M. R., & Haller, J. (2001) · Springer eBooks · doi:10.1007/978-1-4757-6238-9_1 · Cited by 2
Self-citation
The Vasopressin V1A Receptor and Aggression
Tan, O., & Bowen, M. T. (2023) · Springer eBooks · doi:10.1007/978-3-030-98711-4_90-1 · Cited by 2

Authors: Roeling, T. A. P., Veening, J. G., Kruk, M. R., Peters, J. P. W., Vermelis, M. E. J., & Nieuwenhuys, R.
Affiliations: Radboud University Nijmegen (NL)
Leiden University (NL)
Corresponding author: Roeling, T.A.P.
ORCID: Peters, J.P.W.
Nieuwenhuys, R.
Venue: Neuroscience
Publisher: Elsevier BV
Published: 1994-04
Volume: 59
Issue: 4
Pages: 1001-1024
ISSN: 0306-4522 (ISSN-L)
DOI: 10.1016/0306-4522(94)90302-6
OpenAlex: W2034313355
Cited by: 126
References: 76
Citations by year: 2025: 3 · 2024: 4 · 2023: 7 · 2022: 2 · 2021: 4 · 2020: 3 · 2019: 4 · 2018: 4 · 2017: 2 · 2016: 6 · 2015: 4 · 2014: 8 · 2013: 4
FWCI: 7.23
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords: efferent projections, aggression, ventromedial hypothalamus, lateral septal nucleus, mediodorsal thalamus, periaqueductal gray, agonistic behavior, rats
MeSH terms: Agonistic Behavior, Animals, Brain Mapping, Brain Stem, Efferent Pathways, Electric Stimulation, Grooming, Hypothalamus, Male, Periaqueductal Gray, Septal Nuclei, Serotonin, Thalamic Nuclei, Ventromedial Hypothalamic Nucleus, Rats, Wistar, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Efferent connections of the hypothalamic “aggression area” in the rat

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks