Cited by 142Phytochemicals and Medicinal PlantsMedicinal Plants and Bioactive CompoundsGinseng Biological Effects and Applications

A comparative pharmacological investigation of Ashwagandha and Ginseng

Grandhi, Anuradha, Mujumdar, A.M., Patwardhan, Bhushan·1994·Journal of Ethnopharmacology

Abstract

The aqueous suspensions of roots of an Indian drug Ashwagandha and the Korean drug Ginseng were tested comparatively for 2 pharmacological activities, namely the anti-stress activity by the 'mice swimming endurance test' and anabolic activity by noting gain in body weights and levator ani muscle in rats. A significant increase in mice swimming time was shown by Ginseng (P < 0.001) and Ashwagandha (P < 0.01) as compared to the control group. Significant increase in body weights in the Ashwagandha treated group (P < 0.05) was better than Ginseng (P < 0.5). Gain in wet weights of the levator ani muscle were also significant in Ginseng (P < 0.001) and Ashwagandha (P < 0.01) treated groups, however, the weight gain of dried levator ani muscles showed comparable results for both these drugs (P < 0.01).

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Registry

Crossref · 10.1016/0378-8741(94)01119-2

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4 of 4 references verified0 citation errors · 0 not checkable

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Authors
Grandhi, A., Mujumdar, A. M., & Patwardhan, B.
Affiliations
Savitribai Phule Pune University (IN)
Corresponding author
Patwardhan, Bhushan
Venue
Journal of Ethnopharmacology
Publisher
Elsevier BV
Published
1994-12
Volume
44
Issue
3
Pages
131-135
ISSN
0378-8741 (ISSN-L)
OpenAlex
W2088319882
Cited by
142
References
8
Citations by year
2026: 2 · 2025: 2 · 2024: 4 · 2023: 6 · 2022: 2 · 2021: 10 · 2020: 8 · 2019: 3 · 2018: 4 · 2017: 7 · 2016: 7 · 2015: 5 · 2014: 7 · 2013: 9 · 2012: 7
FWCI
3.71
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Ethnopharmacology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Phytochemicals and Medicinal Plants
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Medicinal Plants and Bioactive Compounds
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ginseng Biological Effects and Applications
Keywords
Withania somnifera, ginseng, Panax ginseng, anti-stress activity, swimming endurance, anabolic activity, weight gain, levator ani muscle, aqueous root extract, comparative pharmacology
MeSH terms
Administration, Oral, Animals, Body Weight, Chromatography, Thin Layer, Physical Exertion, Panax, Male, Muscles, Plant Extracts, Plants, Medicinal, Stress, Physiological, Swimming, Withania, Mice, Rats

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