The aphrodisiac and adaptogenic properties of ginseng
Abstract
Ginseng is the root of the perennial herbs of Panax quinquefolium and Panax ginseng which contain a series of tetracyclic triterpenoid saponins (ginsenosides) as active ingredients. It is considered a tonic or adaptogenic that enhances physical performance (including sexual), promotes vitality and increases resistance to stress and ageing. The adaptogenic properties of ginseng are believed to be due to its effects on hypothalamic-pituitary-adrenal axis, resulting in elevated plasma corticotropin and corticosteroids levels. When used appropriately, ginseng appears to be safe. Nevertheless, documented side effects include hypertension, diarrhoea, restlessness, mastalgia and vaginal bleeding.
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The adaptogenic properties of Panax ginseng extract are considered to be due to the ginsenosides.
“It is considered that the adaptogenic properties of Panax ginseng extract are due to the ginsenosides [27].”
From Plant Adaptogens—History and Future Perspectives (2021) · cites this paper as [27]
The exact mechanism of adaptogenic action of Panax ginseng is unknown, but it is supposed to affect the hypothalamic-pituitary-adrenal axis and have an antioxidant effect.
“The exact mechanism of adaptogenic action of Panax ginseng is unknown, but it is supposed that it affects the hypothalamic-pituitary-adrenal axis in Figure 2 and the antioxidant effect [24,27,28,29].”
From Plant Adaptogens—History and Future Perspectives (2021) · cites this paper as [27]
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- Authors
- Nocerino, E., Amato, M., & Izzo, A. A.
- Affiliations
- University of Naples Federico II (IT)
- Corresponding author
- Izzo, Angelo A
- ORCID
- Izzo, Angelo A
- Venue
- Fitoterapia
- Publisher
- Elsevier BV
- Published
- 2000-08
- Volume
- 71
- Pages
- S1-S5
- ISSN
- 0367-326X (ISSN-L)
- OpenAlex
- W2150490050
- Cited by
- 229
- References
- 26
- Citations by year
- 2026: 2 · 2025: 10 · 2024: 8 · 2023: 11 · 2022: 7 · 2021: 12 · 2020: 10 · 2019: 10 · 2018: 11 · 2017: 10 · 2016: 15 · 2015: 7 · 2014: 9 · 2013: 16 · 2012: 18
- FWCI
- 0.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Fitoterapia (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ginseng Biological Effects and Applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Medicinal Plants and Bioactive Compounds
- Health Sciences › Medicine › Complementary and alternative medicine › Traditional Chinese Medicine Analysis
- Keywords
- ginseng, Panax quinquefolius, Panax ginseng, ginsenosides, triterpenoid saponins, aphrodisiac effect, adaptogenic properties, hypothalamic-pituitary-adrenal axis, corticosteroids, stress tolerance, aging, sexual performance, adverse effects, safety
- MeSH terms
- Aphrodisiacs, Drugs, Chinese Herbal, Panax, Humans, Phytotherapy, Plant Roots
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