The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons
Open accessAbstract
In the neurological mutant mouse reeler, the histological organization of the neocortex develops abnormally and essentially results in an inversion of the relative positions of the cortical layers. The reeler mutation, therefore, provides an insight into the molecular mechanisms underlying the formation of the cortical layers. We have generated a monoclonal antibody (CR-50) that probes a distinct allelic antigen present in wild-type but not in reeler mutant mice. CR-50 reacted specifically with Cajal-Retzius neurons, one of the first cortical neurons to differentiate in the neocortex, but whose functional role is not known. When dissociated cerebral cortical cells were incubated with CR-50 in reaggregation culture, the genotype-dependent histogenetic assembly of wild-type cortical cells resembled that of reeler mutants. These findings revealed that the selective expression of a distinct molecule on Cajal-Retzius neurons is critical for the normal lamination of cortical neurons in the mammalian neocortex.
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In the citing paper
“These data suggest that Reelin proteins are assembled and anchored to the surface of a cell membrane of the Reelin-secreting cells.”
From Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody (2000) · cites this paper as [13]
In the citing paper
“The CR-50 antibody has neutralizing activity of Reelin both in vitro and in vivo (13, 19–21).”
From Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody (2000) · cites this paper as [13]
In the citing paper
“CR-50 antibody shows a function-blocking effect on Reelin from around this concentration (13)”
From Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody (2000) · cites this paper as [13]
In the citing paper
“some of the secreted Reelin is anchored to the surface of the Reelin-producing cells by an unknown mechanism.”
From Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody (2000) · cites this paper as [13]
In the citing paper
“This epitope region is essential for the Reelin functions, because CR-50 antibody inhibits laminar pattern formation in cortical reaggregation cultures (13), Purkinje cell alignment in cerebellar explant cultures (20), and an axonal branching pattern in the entorhinohippocampal pathway in vitro (19) and disrupts hippocampal development in vivo (21).”
From Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody (2000) · cites this paper as [13]
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“CR cells were first recognized through their expression of secretory glycoprotein, Reelin (Reln) (D’Arcangelo et al., 1995; Ogawa et al., 1995), and the functional study of CR cells has largely focused on their regulation of radial migration in subsequent-born projection neurons through diffusive…”
BackgroundMeyer, G. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.12.1225 · Cited by 65
“Reln is a large extracellular matrix glycoprotein, secreted by Cajal–Retzius cells in the MZ of the developing cortex (D’Arcangelo et al., 1995; Ogawa et al., 1995 ), where it plays a crucial role in the establishment of the inside-out gradient of the cortical plate (Caviness and Sidman, 1973).”
BackgroundMechanism and significance of specific proteolytic cleavage of Reelin
Kohno, S., Kohno, T., Nakano, Y., Suzuki, K. M., Ishii, M., Tagami, H., Baba, A., & Hattori, M. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.01.039 · Cited by 65
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Kanold, P. O. (2004) · Neuroreport · doi:10.1097/00001756-200410050-00001 · Cited by 65
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BackgroundCXCL12 Signaling in the Development of the Nervous System
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“Reelin-positive Cajal-Retzius neurons (Ogawa et al., 1995) developed normally in layer 1 in the E18.”
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“Many researchers suggest that layer 1, and particularly the Cajal–Retzius neurons, play an important role in attracting and guiding subsequent neurons to their proper positions (e.g. Caviness and Rakic, 1978; Marin-Padilla, 1984, 1998; Ogawa et al., 1995).”
BackgroundMethodDeller, T., Drakew, A., & Frotscher, M. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7020 · Cited by 61
Reelin mRNA expression during embryonic brain development in the turtleEmys orbicularis
Bernier, B., Bar, I., Pieau, C., de Rouvroit, C. L., & Goffinet, A. M. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19991025)413:3 · Cited by 62
Molecular Mechanisms Governing Competitive Synaptic Wiring in Cerebellar Purkinje Cells
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“…caused by deletion in a gene encoding extracellular matrix protein reelin that controls neuronal migration, and the resulting ectopia of reeler PCs in subcortical regions leads to spatial segregation from granule cell environment (D’Arcangelo et al. 1995; Hirotsune et al. 1995; Ogawa et al. 1995).”
BackgroundMultisensory cortical processing and dysfunction across the neuropsychiatric spectrum
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“Reelin is an extracellular protein secreted by Cajal– Retzius cells in the marginal zone (MZ) and has critical roles in the formation of the laminar structure of the neocortex (Bar et al., 1995; D’Arcangelo et al., 1995; Ogawa et al., 1995).”
BackgroundReelin Induces Branching of Neurons and Radial Glial Cells during Corticogenesis
Chai, X., Fan, L., Shao, H., Lu, X., Zhang, W., Li, J., Wang, J., Chen, S., Frotscher, M., & Zhao, S. (2014) · Cerebral Cortex · doi:10.1093/cercor/bhu216 · Cited by 62
“Reelin, synthesized and secreted by CR cells, is located in the MZ of the developing cerebral cortex as revealed by in situ hybridization and immunocytochemistry for Reelin (D’Arcangelo et al. 1995, 1997; Ogawa et al. 1995; de Bergeyck et al. 1997; Schiffmann et al. 1997; Drakew et al. 1998).”
Hu, H., Li, J., Gagen, C. S., Gray, N. W., Zhang, Z., Qi, Y., & Zhang, P. (2010) · The Journal of Comparative Neurology · doi:10.1002/cne.22572 · Cited by 56
“CR-50 antibody specifically recognized Cajal-Retzius cells and its immunoreactivity was lost in the reeler mice deficient in Reelin (Ogawa et al., 1995).”
BackgroundReelin Glycoprotein in Autism and Schizophrenia
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“For instance, Reelin has been suggested to function as an inhibitory or stop signal for neuronal migration (Ogawa et al., 1995; D’Arcangelo et al., 1997; Curran and D’Arcangelo, 1998; Frotscher, 1998; Pearlman et al., 1998; Dulabon et al., 2000; Walsh and Goffinet, 2000; Yip et al., 2000; Nishikawa…”
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“…culture, reelin is secreted into the extracellular space independently of neurotransmitter release (Lacor et al., 2000) and influences the position of migrating neurons (D’Arcangelo et al., 1995, 1997; Ogawa et al., 1995; Rugarli and Ballabio, 1995; Curran and D’Arcangelo, 1998; Frotscher, 1998).”
BackgroundGli3 is required for the specification and differentiation of preplate neurons
Theil, T. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.08.033 · Cited by 51
“Lack of reelin, as in the reeler mouse mutant (Curran and D’Arcangelo, 1998; D’Arcangelo et al., 1995; Ogawa et al., 1995) and in human congenital lissencephaly patients (Hong et al., 2000), or disturbance of the reelin signalling pathway (Howell et al., 1997; Sheldon et al., 1997; Trommsdorff et…”
BackgroundKoliatsos, V. E., Dawson, T. M., Kecojević, A., Zhou, Y., Wang, Y.-F., & Huang, K.-X. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404364101 · Cited by 53
Reelin transiently promotes N-cadherin–dependent neuronal adhesion during mouse cortical development
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“Genotype-dependent differences in the cortical cell aggregation pattern between reeler and wild-type mice were previously analyzed using a rotation culture of dissociated cortical cells (6, 28).”
MethodSelf-citationPeriventricular Heterotopia and the Genetics of Neuronal Migration in the Cerebral Cortex
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Abellán, A., Menuet, A., Dehay, C., Medina, L. M., & Rétaux, S. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp242 · Cited by 56
“Indeed, in ‘‘reeler’’ mice (Falconer 1951) that lack functional reelin (Ogawa et al. 1995; D’Arcangelo et al. 1995; D’Arcangelo et al. 1996), cortical layers are inverted (reviewed in Tissir and Goffinet 2003) and this phenotype is rescued by providing exogenous reelin (Magdaleno et al. 2002;…”
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“Calcium imaging experiments were performed with a custom-built randomaccess two-photon laser-scanning microscope (Otsu et al., 2008).”
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“In the absence of Reelin, later born cortical neurons fail to migrate past the earlier born neurons, resulting in inverted cortical layers (Ogawa and others 1995).”
Expression of neuronal nitric oxide synthase during embryonic development of the rat cerebral cortex
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“Reelin regulates neuron-neuron interactions ex vivo and in vivo (Kubo et al., 2010; Ogawa et al., 1995).”
BackgroundLatsari, M., Dori, I., Antonopoulos, J., Chiotelli, M., & Dinopoulos, A. (2002) · The Journal of Comparative Neurology · doi:10.1002/cne.10156 · Cited by 53
“Cajal-Retzius cells, the principal cells of the marginal zone, provide signals important for the migration of later born cells and lamination during neocortical development (D’Arcangelo et al., 1995; Ogawa et al., 1995; Frotscher, 1998).”
BackgroundEthanol Induces Heterotopias in Organotypic Cultures of Rat Cerebral Cortex
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Reelin and Disabled-1 Expression in Developing and Mature Human Cortical Neurons
Deguchi, K., Inoue, K., Avila, W. E., Lopez-Terrada, D. H., Antalffy, B. A., Quattrocchi, C. C., Sheldon, M., Mikoshiba, K., D’Arcangelo, G., & Armstrong, D. L. (2003) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/62.6.676 · Cited by 54
“In the immature mouse cortex and hippocampus, Reln, which is identified with the CR50 antibody (7, 8), is expressed in the marginal zone by Cajal-Retzius (CR) neurons, a population of early-generated cells, and it provides a positional cue that determines the development of the normal ‘‘inside-out’’ cortical layering…”
BackgroundMethodInfluentialGo or Stop? Divergent Roles of Reelin in Radial Neuronal Migration
Zhao, S., & Frotscher, M. (2010) · The Neuroscientist · doi:10.1177/1073858410367521 · Cited by 53
Neuronal Polarity in the Embryonic Mammalian Cerebral Cortex
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“Reelin is secreted by Cajal-Retzius cells located in the MZ right above the CP (D’Arcangelo et al., 1995; Ogawa et al., 1995).”
BackgroundNeuronal cell migration for the developmental formation of the mammalian striatum
Hamasaki, T., Goto, S., Nishikawa, S., & Ushio, Y. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(02)00216-3 · Cited by 57
Topical Review: Neuronal Migration in Developmental Disorders
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A novel mode of tangential migration of cortical projection neurons
Britanova, O. V., Alifragis, P., Junek, S., Jones, K. R., Gruß, P., & Tarabykin, V. S. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.06.040 · Cited by 54
“A key molecule in this process is Reelin, an extracellular matrix protein secreted by Cajal–Retzius cells in the MZ that when mutated, causes a disruption in neuronal migration (D'Arcangelo, 2001; D'Arcangelo et al., 1995; Drakew et al., 1998; Ogawa et al., 1995).”
BackgroundEarly Telencephalic Migration Topographically Converging in the Olfactory Cortex
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“…the cells described by Nomura et al. (2006) strongly express CB and Reln, whereas the dorsally generated cells that migrate by the PP and express Reln are Cajal-Retzius cells and they do not express CB (Ogawa et al. 1995; Schiffmann et al. 1997; Meyer and Goffinet 1998; Garcı́a-Moreno et al. 2007).”
BackgroundBorrell, V., Ruiz, M., del Rı́o, J. A., & Soriano, E. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7022 · Cited by 52
Reelin: Diverse roles in central nervous system development, health and disease
Armstrong, N. C., Anderson, R. C., & McDermott, K. W. G. (2019) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2019.04.009 · Cited by 52
“In 1994, an allele unique to the reeler mouse was identified by means of insertional mutagenesis (Miao et al., 1994), enabling the RELN gene to be mapped on chromosome 7q22 (D’Arcangelo et al., 1995; Ogawa et al, 1995).”
Backgroundp73 and Reelin in Cajal-Retzius Cells of the Developing Human Hippocampal Formation
Ábrahám, H. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh010 · Cited by 51
“The presence of reelin-positive interneurons in adult life (Pesold et al., 1998; Pérez-García et al., 2001; Abraham and Meyer, 2003) indicates that reelin fulfills multiple functions, from a role in the establishment of the radial glia scaffold at the onset of corticogenesis (Förster et al., 2002)…”
BackgroundPatterning, Regionalization, and Cell Differentiation in the Forebrain
Marín, Ó., & Rubenstein, J. L. R. (2002) · Elsevier eBooks · doi:10.1016/b978-012597951-1/50007-x · Cited by 50
Step by step: cells with multiple functions in cortical circuit assembly
Cossart, R., & Garel, S. (2022) · Nature reviews. Neuroscience · doi:10.1038/s41583-022-00585-6 · Cited by 54
Quattrocolo, G., & Maccaferri, G. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1407-14.2014 · Cited by 50
“The discovery of their immunoreactivity to the allelic antigen missing in the reeler mouse (Ogawa et al., 1995), together with the identification of this gene as reelin (D’Arcangelo et al., 1995), led to the proposal that Cajal-Retzius cells are critical for the correct assembly of maturing…”
BackgroundAnstötz, M., Huang, H., Marchionni, I., Haumann, I., Maccaferri, G., & Lübke, J. H. R. (2015) · Cerebral Cortex · doi:10.1093/cercor/bhv271 · Cited by 54
“This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.”
BackgroundMethodInfluentialItoh, Y., Higuchi, M., Oishi, K., Kishi, Y., Okazaki, T., Sakai, H., Miyata, T., Nakajima, K., & Gotoh, Y. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1516321113 · Cited by 54
Self-citationSobue, A., Kushima, I., Nagai, T., Shan, W., Kohno, T., Aleksić, B., Aoyama, Y., Mori, D., Arioka, Y., Kawano, N., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-31390-w · Cited by 49
Ignatova, N. G., Sindic, C., & Goffinet, A. M. (2004) · Neurobiology of Disease · doi:10.1016/j.nbd.2003.11.008 · Cited by 49
Differential gene expression in migratory streams of cortical interneurons
Antypa, M., Faux, C., Eichele, G., Parnavelas, J. G., & Andrews, W. D. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07896.x · Cited by 49
“Similarly, Reelin, which is predominantly expressed by CR cells in the PPL ⁄ MZ and is known to act as a chemoattractant for migrating neurons (Ogawa et al., 1995), may also contribute to a permissive environment that promotes the migration of interneurons.”
BackgroundMethodLászló, Z. I., & Lele, Z. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.972059 · Cited by 49
“…synaptic activity strengthens synaptic adhesion and spine morphology and vice versa, strong synaptic adhesion leads to maturation of dendritic spines and elevated synaptic transmission (Tanaka et al., 2000; Togashi et al., 2002; Okamura et al., 2004; Bozdagi et al., 2010; Mendez et al., 2010).”
BackgroundRole of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons
Wines-Samuelson, M., Handler, M., & Shen, J. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.09.024 · Cited by 49
“For detection of Reelin, slides were processed using the Histomouse SP kit (Zymed Laboratories, San Francisco, CA) following the manufacturer’s suggestions, except that the brain sections were incubated with anti-Reelin monoclonal antibodies CR50 (1:400) (Ogawa et al., 1995) or G10 (1:1000) (de Bergeyck et al.”
BackgroundMethodInfluentialReelin and apoE actions on signal transduction, synaptic function and memory formation
Rogers, J. T., & Weeber, E. J. (2008) · Neuron Glia Biology · doi:10.1017/s1740925x09990184 · Cited by 48
“Reelin secretion is required for ventricular migrating neurons to form the highly laminated structures within the neocortex, hippocampus and cerebellum (D’Arcangelo et al., 1995; Ogawa et al., 1995; Aguilo et al., 1999; Soda et al., 2003).”
BackgroundMolecular Pathways Controlling the Sequential Steps of Cortical Projection Neuron Migration
Hippenmeyer, S. (2013) · Advances in experimental medicine and biology · doi:10.1007/978-94-007-7687-6_1 · Cited by 48
Hamre, K. M., & Goldowitz, D. (1997) · Development · doi:10.1242/dev.124.21.4201 · Cited by 49
Supèr, H., Martı́nez, A., & Soriano, E. (1997) · Developmental Brain Research · doi:10.1016/s0165-3806(96)00155-1 · Cited by 49
Role of Fgf8 signalling in the specification of rostral Cajal-Retzius cells
Zimmer, C., Lee, J., Griveau, A., Arber, S., Pierani, A., Garel, S., & Guillemot, F. (2009) · Development · doi:10.1242/dev.041178 · Cited by 51
“…Borello et al., 2008; Chi et al., 2003; Cholfin and Rubenstein, 2008; FukuchiShimogori and Grove, 2001; Fukuchi-Shimogori and Grove, 2003; Gimeno and Martinez, 2007; Gutin et al., 2006; Lee et al., 2000; Ohkubo et al., 2002; Shanmugalingam et al., 2000; Storm et al., 2006; Storm et al., 2003).”
BackgroundAbsence of Tangentially Migrating Glutamatergic Neurons in the Developing Avian Brain
García‐Moreno, F., Anderton, E., Jankowska, M., Begbie, J., Encinas, J. M., Irimia, M., & Molnár, Z. (2018) · Cell Reports · doi:10.1016/j.celrep.2017.12.032 · Cited by 51
“The neurogenesis-related functions of Cajal-Retzius cells (Ogawa et al., 1995; Supèr et al., 2000) and the control of early circuitry by subplate cells (Hoerder-Suabedissen and Molnár, 2015) are essential platforms for the subsequent developmental program of the mammalian DP.”
BackgroundInfluentialAn Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System
Donato, V. D., Santis, F. D., Albadri, S., Auer, T. O., Duroure, K., Charpentier, M., Concordet, J., Gebhardt, C., & Bene, F. D. (2018) · Neuron · doi:10.1016/j.neuron.2018.01.030 · Cited by 48
“, 1997), a repellent cue to subplate neurons (Ogawa et al., 1995), or as detachment/stop signal from radial glia for neurons during the terminal phase of migration (Dulabon et al.”
Chapter 21 Evolving concepts of cortical radial and areal specification
RAKIC, P. T. (2002) · Progress in brain research · doi:10.1016/s0079-6123(02)36023-0 · Cited by 48
Kerr, M. L., & Small, D. H. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20408 · Cited by 48
“Dab1 is almost exclusively expressed in the brain (Howell et al., 1997) and is a downstream messenger of the Reelin pathway, which is involved in neuronal migration to cortical layers during development (Ogawa et al., 1995).”
BackgroundHammond, V. E., Howell, B. W., Godinho, L., & Tan, S. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-22-08798.2001 · Cited by 45
Gleeson, J. G. (2001) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.1024 · Cited by 48
Ina, A., Sugiyama, M., Konno, J., Yoshida, S., Ohmomo, H., Nogami, H., Shutoh, F., & Hisano, S. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05703.x · Cited by 48
Chevassus-au-Louis, N., & Represa, A. (1999) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050367 · Cited by 47
Naqui, S. Z. H., Harris, B. S., Thomaidou, D., & Parnavelas, J. G. (1999) · Developmental Brain Research · doi:10.1016/s0165-3806(99)00003-6 · Cited by 47
Martinez-Galan, J. R., del Rey, F. E., de Escobar, G. M., Santacana, M., & Ruiz‐Marcos, A. (2004) · Developmental Brain Research · doi:10.1016/j.devbrainres.2004.08.002 · Cited by 45
Genes that regulate neuronal migration in the cerebral cortex
Allen, K. M., & Walsh, C. A. (1999) · Epilepsy Research · doi:10.1016/s0920-1211(99)00048-0 · Cited by 46
“Reelin is synthesized and secreted by the Cajal-Retzius cells of layer 1 of the cerebral cortex, at a distance from the migrating cells which appear to require Reelin for appropriate guidance (Ogawa et al., 1995).”
BackgroundTesfaye, M., Jaholkowski, P., Hindley, G. F. L., Shadrin, A. A., Rahman, Z., Bahrami, S., Lin, A., Holen, B., Parker, N., Cheng, W., et al. (2023) · Genome Medicine · doi:10.1186/s13073-023-01212-4 · Cited by 46
“RELN-ApoER2 pathway regulates neurodevelopmental processes in the central [71], and peripheral nervous system [72], and may have a role in the maintenance of the intestinal epithelial barrier [73, 74].”
BackgroundPolarity Regulation in Migrating Neurons in the Cortex
Reiner, O., & Sapir, T. (2009) · Molecular Neurobiology · doi:10.1007/s12035-009-8065-0 · Cited by 48
Developmental disorders of the midbrain and hindbrain
Barkovich, A. J. (2012) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2012.00007 · Cited by 48
Acute inactivation of the serine-threonine kinase Stk25 disrupts neuronal migration
Matsuki, T., Chen, J., & Howell, B. W. (2013) · Neural Development · doi:10.1186/1749-8104-8-21 · Cited by 46
“The dab1 mutant mice and the Reeler mutant, which fails to make or secrete the Reelin protein, have very similar lamination defects in the neocortex, hippocampus and cerebellum, among other regions of the central nervous system [5-8].”
Hayashi, S., Okamoto, N., Chinen, Y., Takanashi, J., Makita, Y., Hata, A., Imoto, I., & Inazawa, J. (2011) · Human Genetics · doi:10.1007/s00439-011-1047-0 · Cited by 45
“RELN plays an important role in neural migration and brain development (D’Arcangelo et al. 1995; Ogawa et al. 1995; Rice et al. 1998), and its mutation is associated with lissencephaly with cerebellar hypoplasia (Hong et al. 2000).”
Background
Metadata
- Authors
- Ogawa, M., Miyata, T., Nakajimat, K., Yagyu, K., Seike, M., Ikenaka, K., Yamamoto, H., & Mikoshibat, K.
- Affiliations
- Kochi Medical School Hospital (JP)
- National Institute for Physiological Sciences (JP)
- National Institute of Neuroscience (JP)
- Institute of Medical Science, The University of Tokyo (JP)
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 1995-05
- Volume
- 14
- Issue
- 5
- Pages
- 899-912
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2036838270
- Cited by
- 889
- References
- 61
- Citations by year
- 2026: 4 · 2025: 12 · 2024: 5 · 2023: 20 · 2022: 16 · 2021: 21 · 2020: 22 · 2019: 25 · 2018: 20 · 2017: 23 · 2016: 22 · 2015: 25 · 2014: 18 · 2013: 32 · 2012: 25
- FWCI
- 10.60
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Axon Guidance and Neuronal Signaling
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- Cajal-Retzius neurons, cortical lamination, neocortex development, histogenesis
- MeSH terms
- Reelin Protein, Animals, Antibodies, Monoclonal, Cell Adhesion, Cell Communication, Cerebral Cortex, Extracellular Space, Hybridomas, Immunohistochemistry, Mice, Neurologic Mutants, Mutation, Nerve Tissue Proteins, Neurons, Serine Endopeptidases, Tissue Distribution, Cell Adhesion Molecules, Neuronal, Extracellular Matrix Proteins, Mice
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