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The concentration of 8-anilino-1-naphthalene sulfonic acid required for healthy male and nonpregnant female samples may be inadequate for samples with increased cortisol-binding globulin.
“Hence, the concentration of ANS required for healthy male and nonpregnant female samples may be inadequate for samples with increased CBG (19 ).”
From Serum cortisol: an up-to-date assessment of routine assay performance (2016) · cites this paper as [19]
Manufacturers may displace cortisol from cortisol-binding globulin by adjusting temperature, lowering pH, or using agents such as salicylate or 8-anilino-1-naphthalene sulfonic acid.
“Nevertheless, it has been reported that manufacturers may displace cortisol from CBG by adjusting temperature, lowering pH or alternatively using agents such as salicylate or 8-anilino-1-napthalene sulfonic acid (ANS) (19 ).”
From Serum cortisol: an up-to-date assessment of routine assay performance (2016) · cites this paper as [19]
The efficiency of 8-anilino-1-naphthalene sulfonic acid is influenced by the concentration of binding proteins.
“However, the efficiency of ANS is influenced by the concentration of binding proteins.”
From Serum cortisol: an up-to-date assessment of routine assay performance (2016) · cites this paper as [19]
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Serum cortisol: an up-to-date assessment of routine assay performance
Hawley, J. M., Owen, L. J., Lockhart, S. J., Monaghan, P. J., Armston, A., Chadwick, C. A., Wilshaw, H., Freire, M., Perry, L., & Keevil, B. G. (2016) · Clinical Chemistry · doi:10.1373/clinchem.2016.255034 · Cited by 95 · see citing works
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The Laboratory Diagnosis of Renal Disease
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Growth Hormone and Steroid Assays’ Problems in Childhood and Puberty
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- Elsevier eBooks (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
- Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
- Keywords
- adrenal cortex, adrenal gland, steroid hormones, glucocorticoids, mineralocorticoids
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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