Characterization of Autophagic Responses in Drosophila melanogaster

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Brand, A. H., & Perrimon, N. (1993) · Development · doi:10.1242/dev.118.2.401 · Cited by 9,510 · see citing works

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy · doi:10.1080/15548627.2015.1100356 · Cited by 5,894 · see citing works

Autophagy and the Integrated Stress Response

Kroemer, G., Mariño, G., & Levine, B. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.09.023 · Cited by 3,506 · see citing works

Dissection of the Autophagosome Maturation Process by a Novel Reporter Protein, Tandem Fluorescent-Tagged LC3

Kimura, S., Noda, T., & Yoshimori, T. (2007) · Autophagy · doi:10.4161/auto.4451 · Cited by 2,278 · see citing works

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Klionsky, D. J., Abeliovich, H., Agostinis, P., Agrawal, D. K., Aliev, G., Askew, D. S., Baba, M., Baehrecke, E. H., Bahr, B. A., Ballabio, A., et al. (2008) · Autophagy · doi:10.4161/auto.5338 · Cited by 2,230 · see citing works

Analysis of genetic mosaics in developing and adult Drosophila tissues

Xu, T., & Rubin, G. M. (1993) · Development · doi:10.1242/dev.117.4.1223 · Cited by 2,067 · see citing works

Role and Regulation of Starvation-Induced Autophagy in the Drosophila Fat Body

Scott, R. C., Schuldiner, O., & Neufeld, T. P. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.07.009 · Cited by 963 · see citing works

Direct Induction of Autophagy by Atg1 Inhibits Cell Growth and Induces Apoptotic Cell Death

Scott, R. C., Juhász, G., & Neufeld, T. P. (2007) · Current Biology · doi:10.1016/j.cub.2006.10.053 · Cited by 852 · see citing works

CYTOPLASMIC COMPONENTS IN HEPATIC CELL LYSOSOMES

Ashford, T. P., & Porter, K. R. (1962) · The Journal of Cell Biology · doi:10.1083/jcb.12.1.198 · Cited by 849 · see citing works

Autophagy: assays and artifacts

Barth, S., Glick, D. R., & Macleod, K. F. (2010) · The Journal of Pathology · doi:10.1002/path.2694 · Cited by 794 · see citing works

Growth Arrest and Autophagy Are Required for Salivary Gland Cell Degradation in Drosophila

Berry, D. L., & Baehrecke, E. H. (2007) · Cell · doi:10.1016/j.cell.2007.10.048 · Cited by 602 · see citing works

Programmed Autophagy in the Drosophila Fat Body Is Induced by Ecdysone through Regulation of the PI3K Pathway

Rusten, T. E., Lindmo, K., Juhász, G., Sass, M., Seglen, P. O., Brech, A., & Stenmark, H. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.07.005 · Cited by 487 · see citing works

Autophagy Is an Essential Component of Drosophila Immunity against Vesicular Stomatitis Virus

Shelly, S. S., Lukinova, N. I., Bambina, S., Berman, A., & Cherry, S. R. (2009) · Immunity · doi:10.1016/j.immuni.2009.02.009 · Cited by 471 · see citing works

An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation

Chang, Y.-Y., & Neufeld, T. P. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-12-1250 · Cited by 418 · see citing works

Autophagy and other vacuolar protein degradation mechanisms

Seglen, P. O., & Bohley, P. (1992) · Cellular and Molecular Life Sciences · doi:10.1007/bf01923509 · Cited by 405 · see citing works

Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila

Denton, D., Shravage, B., Simin, R., Mills, K., Berry, D. L., Baehrecke, E. H., & Kumar, S. (2009) · Current Biology · doi:10.1016/j.cub.2009.08.042 · Cited by 385 · see citing works

Ref(2)P, the <i>Drosophila melanogaster</i> homologue of mammalian p62, is required for the formation of protein aggregates in adult brain

Nezis, I. P., Simonsen, A., Sagona, A. P., Finley, K., Gaumer, S., Contamine, D., Rusten, T. E., Stenmark, H., & Brech, A. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200711108 · Cited by 370 · see citing works

Steroid regulation of autophagic programmed cell death during development

Lee, C.-Y., & Baehrecke, E. H. (2001) · Development · doi:10.1242/dev.128.8.1443 · Cited by 336 · see citing works

ESCRTs and Fab1 Regulate Distinct Steps of Autophagy

Rusten, T. E., Vaccari, T., Lindmo, K., Rodahl, L. M., Nezis, I. P., Sem-Jacobsen, C., Wendler, F., Vincent, J., Brech, A., Bilder, D. H., et al. (2007) · Current Biology · doi:10.1016/j.cub.2007.09.032 · Cited by 332 · see citing works

The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila

Juhász, G., Hill, J. H., Yan, Y., Sass, M., Baehrecke, E. H., Backer, J., & Neufeld, T. P. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200712051 · Cited by 311 · see citing works

Seeing is believing: The impact of electron microscopy on autophagy research

Eskelinen, E.-L., Reggiori, F., Baba, M., Kovács, A. L., & Seglen, P. O. (2011) · Autophagy · doi:10.4161/auto.7.9.15760 · Cited by 281 · see citing works

Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late <i>Drosophila melanogaster</i> oogenesis

Nezis, I. P., Shravage, B. V., Sagona, A. P., Lamark, T., Bjørkøy, G., Johansen, T., Rusten, T. E., Brech, A., Baehrecke, E. H., & Stenmark, H. (2010) · Journal of Cell Biology · doi:10.1083/jcb.201002035 · Cited by 252 · see citing works

p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects

Bartlett, B. J., Isakson, P., Lewerenz, J., Sanchez, H., Kotzebue, R. W., Cumming, R. C., Harris, G. L., Nezis, I. P., Schubert, D. R., Simonsen, A., et al. (2011) · Autophagy · doi:10.4161/auto.7.6.14943 · Cited by 215 · see citing works

Steroid Regulation of Midgut Cell Death during Drosophila Development

Lee, C.-Y., Cooksey, B. A. K., & Baehrecke, E. H. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0784 · Cited by 214 · see citing works

Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during <i>Drosophila melanogaster</i> oogenesis

Hou, Y.-C. C., Chittaranjan, S., Barbosa, S. G., McCall, K., & Gorski, S. M. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200712091 · Cited by 180 · see citing works

Autophagy as a pro‐death pathway

Denton, D., Xu, T., & Kumar, S. (2015) · Immunology and Cell Biology · doi:10.1038/icb.2014.85 · Cited by 168 · see citing works

Autophagy in Drosophila ovaries is induced by starvation and is required for oogenesis

Barth, J. M. I., Szabad, J., Hafen, E., & Köhler, K. (2011) · Cell Death &amp; Differentiation · doi:10.1038/cdd.2010.157 · Cited by 165 · see citing works

Chapter 29 Methods for Quantitative Analysis of Transcription in Larvae and Prepupae

Andres, A. J., & Thummel, C. S. (1994) · Methods in cell biology · doi:10.1016/s0091-679x(08)60932-2 · Cited by 155 · see citing works

Cell death during<i>Drosophila melanogaster</i>early oogenesis is mediated through autophagy

Nezis, I. P., Lamark, T., Velentzas, A. D., Rusten, T. E., Bjørkøy, G., Johansen, T., Papassideri, I. S., Stravopodis, D. J., Margaritis, L. H., Stenmark, H., et al. (2009) · Autophagy · doi:10.4161/auto.5.3.7454 · Cited by 132 · see citing works

HDAC6 at the Intersection of Autophagy, the Ubiquitin-proteasome System, and Neurodegeneration

Pandey, U. B., Batlevi, Y., Baehrecke, E. H., & Taylor, J. P. (2007) · Autophagy · doi:10.4161/auto.5050 · Cited by 124 · see citing works

Activation of the cAMP/PKA signaling pathway is required for post-ecdysial cell death in wing epidermal cells ofDrosophila melanogaster

Kimura, K., Kodama, A., Hayasaka, Y., et al. (2004) · Development · doi:10.1242/dev.01049 · Cited by 120 · see citing works

The Drosophila homolog of Aut1 is essential for autophagy and development

Juhász, G., Csikós, G., Sinka, R., Erdélyi, M., & Sass, M. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00431-9 · Cited by 105 · see citing works

Eaten alive: novel insights into autophagy from multicellular model systems

Zhang, H., & Baehrecke, E. H. (2015) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.03.001 · Cited by 102 · see citing works

Ecdysone-induced expression of the caspase DRONC during hormone-dependent programmed cell death in Drosophila is regulated by Broad-Complex

Cakouros, D., Daish, T., Martin, D. N., Baehrecke, E. H., & Kumar, S. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200201034 · Cited by 99 · see citing works

Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila

Denton, D., Chang, T.-K., Nicolson, S., Shravage, B., Simin, R., Baehrecke, E. H., & Kumar, S. (2012) · Cell Death &amp; Differentiation · doi:10.1038/cdd.2012.43 · Cited by 81 · see citing works

The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates

Lindmo, K., Brech, A., Finley, K. D., Gaumer, S., Contamine, D., Rusten, T. E., & Stenmark, H. (2008) · Autophagy · doi:10.4161/auto.5829 · Cited by 76 · see citing works

Distinct requirements of Autophagy-related genes in programmed cell death

Xu, T., Nicolson, S., Denton, D., & Kumar, S. (2015) · Cell Death &amp; Differentiation · doi:10.1038/cdd.2015.28 · Cited by 75 · see citing works

Dopaminergic expression of the Parkinsonian gene LRRK2-G2019S leads to non-autonomous visual neurodegeneration, accelerated by increased neural demands for energy

Hindle, S. J., Afsari, F., Stark, M., Middleton, C. A., Evans, G. J., Sweeney, S. T., & Elliott, C. J. H. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt061 · Cited by 71 · see citing works

Autophagy promotes caspase-dependent cell death during Drosophila development

Mohseni, N., McMillan, S. C., Chaudhary, R., Mok, J., & Reed, B. H. (2009) · Autophagy · doi:10.4161/auto.5.3.7444 · Cited by 70 · see citing works

LysoTracker Staining to Aid in Monitoring Autophagy in DrosophilaPreprint

DeVorkin, L., & Gorski, S. M. (2014) · Cold Spring Harbor Protocols · doi:10.1101/pdb.prot080325 · Cited by 62 · see citing works

UTX coordinates steroid hormone-mediated autophagy and cell death

Denton, D., Aung-Htut, M. T., Lorensuhewa, N., Nicolson, S., Zhu, W., Mills, K., Cakouros, D., Bergmann, A., & Kumar, S. (2013) · Nature Communications · doi:10.1038/ncomms3916 · Cited by 58 · see citing works

Cutting a fine figure

Lucocq, J. M., & Hacker, C. (2013) · Autophagy · doi:10.4161/auto.25570 · Cited by 56 · see citing works

Ecdysone receptor (EcR) suppresses lipid accumulation in the Drosophila fat body via transcription control

Kamoshida, Y., Fujiyama, S., Kimura, S., Suzuki, E., Lim, J., Shiozaki-Sato, Y., Kato, S., & Takeyama, K. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.03.135 · Cited by 52 · see citing works

Ecdysone-mediated programmed cell death in Drosophila

Nicolson, S., Denton, D., & Kumar, S. (2015) · The International Journal of Developmental Biology · doi:10.1387/ijdb.150055sk · Cited by 52 · see citing works

Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis

Kim, M., Semple, I. A., Kim, B. Y., Kiers, A., Nam, S., Park, H., Park, H., Ro, S., Kim, J.-S., Juhász, G., et al. (2015) · Autophagy · doi:10.1080/15548627.2015.1063766 · Cited by 48 · see citing works

Atg9 is required for intraluminal vesicles in amphisomes and autolysosomes

Bader, C. A., Shandala, T., Ng, Y., Johnson, I. R., & Brooks, D. A. (2015) · Biology Open · doi:10.1242/bio.013979 · Cited by 47 · see citing works

Ultrastructure of the preparative phase of cell death in the larval fat body of Drosophila melanogaster

Butterworth, F. M., & Forrest, E. C. (1984) · Tissue and Cell · doi:10.1016/0040-8166(84)90047-8 · Cited by 33 · see citing works

Distinct promoter regions regulate spatial and temporal expression of the Drosophila caspase dronc

Daish, T., Cakouros, D., & Kumar, S. (2003) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401312 · Cited by 32 · see citing works

Immunological cross-reactions and interactions between the Drosophila melanogaster ref(2)P protein and sigma rhabdovirus proteins

Wyers, F., Dru, P., Simonet, B., & Contamine, D. (1993) · Journal of Virology · doi:10.1128/jvi.67.6.3208-3216.1993 · Cited by 27 · see citing works

Chapter Thirty‐Five Quantitative Analysis of Autophagic Activity in Drosophila Neural Tissues by Measuring the Turnover Rates of Pathway Substrates

Cumming, R. C., Simonsen, A., & Finley, K. D. (2008) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(08)03235-7 · Cited by 21 · see citing works

Genetic Manipulation of Autophagy in the Drosophila OvaryPreprint

DeVorkin, L., & Gorski, S. M. (2014) · Cold Spring Harbor Protocols · doi:10.1101/pdb.prot080358 · Cited by 10 · see citing works

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death &amp; Differentiation · doi:10.1038/s41418-017-0012-4 · Cited by 6,680 · see citing works

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) ¹

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy · doi:10.1080/15548627.2020.1797280 · Cited by 2,622 · see citing works

Drosophilids with darker cuticle have higher body temperature under light

Freoa, L., Chevin, L., Christol, P., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-30652-6 · Cited by 14 · see citing works

Drosophilid cuticle pigmentation impacts body temperaturePreprint

Freoa, L., Chevin, L., Christol, P., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.12.03.518031 · Cited by 1 · see citing works

Analysis of Drosophila melanogaster Lifespan

Landis, G. N., Doherty, D. V., & Tower, J. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0592-9_4 · Cited by 33 · see citing works

The art and design of genetic screens: Drosophila melanogaster

St Johnston, D. (2002) · Nature Reviews Genetics · doi:10.1038/nrg751 · Cited by 644 · see citing works

Methods to Assay the Behavior of Drosophila melanogaster for Toxicity Study

Xiao, G. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1514-0_4 · Cited by 6 · see citing works