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Cancer stem cells: Radioresistance, prediction of radiotherapy outcome and specific targets for combined treatments
Open accessAbstract
Inactivation of cancer stem cells (CSCs) is of utmost importance for tumor cure after radiotherapy. An increasing body of evidence complies with a higher radioresistance of CSCs compared to the mass of tumor cells, supporting the use of CSC related biomarkers for prediction of radiotherapy outcome. Treatment individualization strategies for patient groups with vastly different risk of recurrence will most likely require application of more than one biomarker. Specifically, inclusion of established biomarkers like tumor size for primary radio(chemo)therapy or human papilloma virus (HPV) infection status in head and neck squamous cell carcinoma seems to be of very high relevance. The high heterogeneity of CSC subclones along with changes of the functional behavior of individual tumors under treatment underlines the importance of the selection of the optimal timepoint(s) of biomarker evaluation, but also provides a potential therapeutic target for combined treatment approaches with irradiation.
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Cites
Radiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma
Stupp, R., Mason, W. P., van den Bent, M. J., Weller, M., Fisher, B., Taphoorn, M. J. B., Belanger, K., Brandes, A. A., Marosi, C., Bogdahn, U., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043330 · Cited by 21,807
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
Gerlinger, M., Rowan, A. J., Horswell, S., Larkin, J., Endesfelder, D., Gronroos, E., Martinez, P., Matthews, N., Stewart, A., Tarpey, P., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1113205 · Cited by 7,774 · cited 1×
“spatially separated samples within primary tumors and their metastases, was not present in all investigated tumor regions [117].”
BackgroundIdentification of human brain tumour initiating cells
Singh, S. K., Hawkins, C., Clarke, I. D., Squire, J. A., Bayani, J., Hide, T., Henkelman, R. M., Cusimano, M. D., & Dirks, P. B. (2004) · Nature · doi:10.1038/nature03128 · Cited by 7,433
ROS function in redox signaling and oxidative stress
Schieber, M., & Chandel, N. S. (2014) · Current Biology · doi:10.1016/j.cub.2014.03.034 · Cited by 6,931
Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer
Ang, K. K., Harris, J., Wheeler, R., Weber, R., Rosenthal, D. I., Nguyen-Tân, P. F., Westra, W. H., Chung, C. H., Jordan, R. C., Lu, C., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0912217 · Cited by 6,566
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Bao, S., Wu, Q., McLendon, R. E., Hao, Y., Shi, Q., Hjelmeland, A. B., Dewhirst, M. W., Bigner, D. D., & Rich, J. N. (2006) · Nature · doi:10.1038/nature05236 · Cited by 6,379
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Trachootham, D., Alexandre, J., & Huang, P. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2803 · Cited by 5,452
Clarke, M. F., Dick, J. E., Dirks, P. B., Eaves, C. J., Jamieson, C. H. M., Jones, D. L., Visvader, J., Weissman, I. L., & Wahl, G. M. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-3126 · Cited by 3,051
Association of reactive oxygen species levels and radioresistance in cancer stem cells
Diehn, M., Cho, R. W., Lobo, N. A., Kalisky, T., Dorie, M. J., Kulp, A. N., Qian, D., Lam, J. S., Ailles, L. E., Wong, M., et al. (2009) · Nature · doi:10.1038/nature07733 · Cited by 2,555
Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
Mohyeldin, A., Garzón-Muvdi, T., & Quiñones-Hinojosa, A. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.07.007 · Cited by 1,535
Stem Cell–like Glioma Cells Promote Tumor Angiogenesis through Vascular Endothelial Growth Factor
Bao, S., Wu, Q., Sathornsumetee, S., Hao, Y., Li, Z., Hjelmeland, A. B., Shi, Q., McLendon, R. E., Bigner, D. D., & Rich, J. N. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-1010 · Cited by 1,345
Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
Schwitalla, S., Fingerle, A. A., Cammareri, P., Nebelsiek, T., Göktuna, S. I., Ziegler, P. K., Canli, O., Heijmans, J., Huels, D. J., Moreaux, G., et al. (2013) · Cell · doi:10.1016/j.cell.2012.12.012 · Cited by 1,068
Harris, I. S., Treloar, A. E., Inoue, S., Sasaki, M., Gorrini, C., Lee, K. C., Yung, K. Y., Brenner, D., Knobbe-Thomsen, C. B., Cox, M. A., et al. (2015) · Cancer Cell · doi:10.1016/j.ccell.2014.11.019 · Cited by 993
Nordsmark, M., Bentzen, S. M., Rudat, V., Brizel, D., Lartigau, E., Stadler, P., Becker, A., Adam, M., Molls, M., Dunst, J., et al. (2005) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2005.06.038 · Cited by 953
Stupp, R., Dietrich, P.-Y., Ostermann, S., Pica, A., Maillard, I. P., Maeder, P., Meuli, R. A., Janzer, R. C., Pizzolato, G., Miralbell, R., et al. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.20.5.1375 · Cited by 856
Exploring the role of cancer stem cells in radioresistance
Baumann, M., Krause, M., & Hill, R. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2419 · Cited by 815
Self-citationVariable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer
Kreso, A., O'Brien, C. A., van Galen, P., Gan, O. I., Notta, F., Brown, A. M. K., Ng, K., Ma, J., Wienholds, E., Dunant, C., et al. (2013) · Science · doi:10.1126/science.1227670 · Cited by 744
Murat, A., Migliavacca, E., Gorlia, T., Lambiv, W. L., Shay, T., Hamou, M.-F., de Tribolet, N., Regli, L., Wick, W., Kouwenhoven, M. C. M., et al. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.15.7164 · Cited by 721
Defining the mode of tumour growth by clonal analysis
Driessens, G., Beck, B., Caauwe, A., Simons, B. D., & Blanpain, C. (2012) · Nature · doi:10.1038/nature11344 · Cited by 717
Radiation-induced cell death mechanisms
Eriksson, D., & Stigbrand, T. (2010) · Tumor Biology · doi:10.1007/s13277-010-0042-8 · Cited by 666
Notch Promotes Radioresistance of Glioma Stem Cells
Wang, J., Wakeman, T. P., Lathia, J. D., Hjelmeland, A. B., Wang, X.-F., White, R. R., Rich, J. N., & Sullenger, B. A. (2010) · Stem Cells · doi:10.1002/stem.261 · Cited by 656
WNT/β-catenin mediates radiation resistance of mouse mammary progenitor cells
Woodward, W. A., Chen, M. S., Behbod, F., Alfaro, M. P., Buchholz, T. A., & Rosen, J. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0606599104 · Cited by 603
Understanding cancer stem cell heterogeneity and plasticity
Tang, D. G. (2012) · Cell Research · doi:10.1038/cr.2012.13 · Cited by 563
Rischin, D., Hicks, R. J., Fisher, R., Binns, D., Corry, J., Porceddu, S., & Peters, L. J. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2005.05.2878 · Cited by 541
CD44 is required for two consecutive steps in HGF/c-Met signaling
Orian-Rousseau, V., Chen, L., Sleeman, J. P., Herrlich, P., & Ponta, H. (2002) · Genes & Development · doi:10.1101/gad.242602 · Cited by 518
Cancer stem cell niche: the place to be
Borovski, T., De Sousa E Melo, F., Vermeulen, L., & Medema, J. P. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-3220 · Cited by 518
HIF Induces Human Embryonic Stem Cell Markers in Cancer Cells
Mathieu, J., Zhang, Z., Zhou, W., Wang, A. J., Heddleston, J. M., Pinna, C. M. A., Hubaud, A., Stadler, B., Choi, M., Bar, M., et al. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-3320 · Cited by 508
The radioresponsiveness of human tumours and the initial slope ofthe cell survival curve
Deacon, J., Peckham, M. J., & Steel, G. G. (1984) · Radiotherapy and Oncology · doi:10.1016/s0167-8140(84)80074-2 · Cited by 467
Overgaard, J. (2011) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2011.03.004 · Cited by 456
ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1
Zhang, P., Wei, Y., Wang, L., Debeb, B. G., Yuan, Y., Zhang, J., Yuan, J., Wang, M., Chen, D., Sun, Y., et al. (2014) · Nature Cell Biology · doi:10.1038/ncb3013 · Cited by 454
Lim, D. A., Cha, S., Mayo, M. C., Chen, M.-H., Keles, E., VandenBerg, S., & Berger, M. S. (2007) · Neuro-Oncology · doi:10.1215/15228517-2007-023 · Cited by 442
Radiation‐Induced Reprogramming of Breast Cancer Cells
Lagadec, C., Vlashi, E., Della Donna, L., Dekmezian, C., & Pajonk, F. (2012) · STEM CELLS · doi:10.1002/stem.1058 · Cited by 401
Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer
Ward, M. J., Thirdborough, S. M., Mellows, T., Riley, C., Harris, S., Suchak, K., Webb, A., Hampton, C., Patel, N. N., Randall, C. J., et al. (2014) · British Journal of Cancer · doi:10.1038/bjc.2013.639 · Cited by 391
Chang, L., Graham, P. H., Hao, J., Ni, J., Bucci, J., Cozzi, P. J., Kearsley, J. H., & Li, Y. (2013) · Cell Death & Disease · doi:10.1038/cddis.2013.407 · Cited by 377
Inflammation and prostate cancer: the role of interleukin 6 ( IL ‐6)
Nguyen, D. P., Li, J., & Tewari, A. K. (2014) · BJU International · doi:10.1111/bju.12452 · Cited by 359
Cancer Stem Cell Analysis and Clinical Outcome in Patients with Glioblastoma Multiforme
Pallini, R., Ricci-Vitiani, L., Banna, G. L., Signore, M., Lombardi, D., Todaro, M., Stassi, G., Martini, M., Maira, G., Larocca, L. M., et al. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-0644 · Cited by 355
Minniti, G., Amelio, D., Amichetti, M., Salvati, M., Muni, R., Bozzao, A., Lanzetta, G., Scarpino, S., Arcella, A., & Enrici, R. M. (2010) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2010.08.020 · Cited by 323
Qiang, L., Wu, T., Zhang, H.-W., Lu, N., Hu, R., Wang, Y.-J., Zhao, L., Chen, F.-H., Wang, X.-T., You, Q.-D., et al. (2012) · Cell Death & Differentiation · doi:10.1038/cdd.2011.95 · Cited by 313
Rieckmann, T., Tribius, S., Grob, T. J., Meyer, F., Busch, C.-J., Petersen, C., Dikomey, E., & Kriegs, M. (2013) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2013.03.013 · Cited by 312
Mortensen, L. S., Johansen, J., Kallehauge, J., Primdahl, H., Busk, M., Lassen, P., Alsner, J., Sørensen, B. S., Toustrup, K., Jakobsen, S., et al. (2012) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2012.09.015 · Cited by 308
Mladenov, E., Magin, S., Soni, A., & Iliakis, G. (2013) · Frontiers in Oncology · doi:10.3389/fonc.2013.00113 · Cited by 290
Zips, D., Zöphel, K., Abolmaali, N., Perrin, R., Abramyuk, A., Haase, R., Appold, S., Steinbach, J., Kotzerke, J., & Baumann, M. (2012) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2012.08.019 · Cited by 280
Self-citationRedox regulation in stem-like cancer cells by CD44 variant isoforms
Nagano, O., Okazaki, S., & Saya, H. (2013) · Oncogene · doi:10.1038/onc.2012.638 · Cited by 280
Overgaard, J., Eriksen, J. G., Nordsmark, M., Alsner, J., & Horsman, M. R. (2005) · The Lancet Oncology · doi:10.1016/s1470-2045(05)70292-8 · Cited by 274
Oxidatively induced DNA damage and its repair in cancer
Dizdaroglu, M. (2015) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2014.11.002 · Cited by 254
Molecular Pathways: Overcoming Radiation Resistance by Targeting DNA Damage Response Pathways
Morgan, M. A., & Lawrence, T. S. (2015) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-13-3229 · Cited by 250
Eustace, A., Mani, N., Span, P. N., Irlam, J. J., Taylor, J., Betts, G. N. J., Denley, H., Miller, C. J., Homer, J. J., Rojas, A. M., et al. (2013) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-13-0542 · Cited by 240
Bradley, J. D., Ieumwananonthachai, N., Purdy, J. A., Wasserman, T. H., Lockett, M. A., Graham, M. V., & Perez, C. A. (2002) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(01)01772-2 · Cited by 236
Szumiel, I. (2015) · International Journal of Radiation Biology · doi:10.3109/09553002.2014.934929 · Cited by 232
Gomez-Casal, R., Bhattacharya, C., Ganesh, N., Bailey, L., Basse, P., Gibson, M., Epperly, M., & Levina, V. (2013) · Molecular Cancer · doi:10.1186/1476-4598-12-94 · Cited by 225
Cojoc, M., Peitzsch, C., Kurth, I., Trautmann, F., Kunz-Schughart, L. A., Telegeev, G. D., Stakhovsky, E. A., Walker, J. R., Simin, K., Lyle, S., et al. (2015) · Cancer Research · doi:10.1158/0008-5472.can-14-1924 · Cited by 223
Self-citationToustrup, K., Sørensen, B. S., Lassen, P., Wiuf, C., Alsner, J., & Overgaard, J. (2012) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2011.09.010 · Cited by 221
Wang, W.-J., Wu, S.-P., Liu, J.-B., Shi, Y.-S., Huang, X., Zhang, Q.-B., & Yao, K.-T. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-1408 · Cited by 212
Lassen, P., Eriksen, J. G., Hamilton-Dutoit, S., Tramm, T., Alsner, J., & Overgaard, J. (2010) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2009.10.008 · Cited by 210
Bourguignon, L. Y. W., Gilad, E., Brightman, A., Diedrich, F., & Singleton, P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m507734200 · Cited by 207
Comparative Analysis of DNA Repair in Stem and Nonstem Glioma Cell Cultures
Ropolo, M., Daga, A., Griffero, F., Foresta, M., Casartelli, G., Zunino, A., Poggi, A., Cappelli, E., Zona, G., Spaziante, R., et al. (2009) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-08-0409 · Cited by 198
Key Roles of Hyaluronan and Its CD44 Receptor in the Stemness and Survival of Cancer Stem Cells
Chanmee, T., Ontong, P., Kimata, K., & Itano, N. (2015) · Frontiers in Oncology · doi:10.3389/fonc.2015.00180 · Cited by 195
Ahmed, S. U., Carruthers, R., Gilmour, L., Yildirim, S., Watts, C., & Chalmers, A. J. (2015) · Cancer Research · doi:10.1158/0008-5472.can-14-3790 · Cited by 194
Malaise, E. P., Fertil, B., Chavaudra, N., & Guichard, M. (1986) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/0360-3016(86)90071-4 · Cited by 192
Discovery of the cancer stem cell related determinants of radioresistance
Peitzsch, C., Kurth, I., Kunz-Schughart, L., Baumann, M., & Dubrovska, A. (2013) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2013.06.003 · Cited by 189
Self-citationWest, C., Davidson, S., Roberts, S., & Hunter, R. (1993) · British Journal of Cancer · doi:10.1038/bjc.1993.434 · Cited by 185
CD44 Expression Predicts Local Recurrence after Radiotherapy in Larynx Cancer
de Jong, M. C., Pramana, J., van der Wal, J. E., Lacko, M., Peutz-Kootstra, C. J., de Jong, J. M., Takes, R. P., Kaanders, J. H., van der Laan, B. F., Wachters, J., et al. (2010) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-0799 · Cited by 185
Lassen, P., Primdahl, H., Johansen, J., Kristensen, C. A., Andersen, E., Andersen, L. J., Evensen, J. F., Eriksen, J. G., & Overgaard, J. (2014) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2014.11.032 · Cited by 168
Antibody Against CD44s Inhibits Pancreatic Tumor Initiation and Postradiation Recurrence in Mice
Li, L., Hao, X., Qin, J., Tang, W., He, F., Smith, A., Zhang, M., Simeone, D. M., Qiao, X. T., Chen, Z.-N., et al. (2014) · Gastroenterology · doi:10.1053/j.gastro.2013.12.035 · Cited by 161
Intratumoral Heterogeneity: From Diversity Comes Resistance
Pribluda, A., de la Cruz, C. C., & Jackson, E. L. (2015) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-14-1213 · Cited by 160
Yaromina, A., Krause, M., Thames, H. D., Rosner, A., Krause, M., Hessel, F., Grenman, R. A., Zips, D., & Baumann, M. A. (2007) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2007.04.020 · Cited by 153
Self-citationHypoxia and anemia: effects on tumor biology and treatment resistance
Vaupel, P. W., & Mayer, A. (2005) · Transfusion Clinique et Biologique · doi:10.1016/j.tracli.2004.11.005 · Cited by 153
Lohaus, F., Linge, A., Tinhofer, I., Budach, V., Gkika, E., Stuschke, M., Balermpas, P., Rödel, C. M., Avlar, M., Grosu, A., et al. (2014) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2014.11.011 · Cited by 151
Self-citationDNA Damage in Cancer Therapeutics: A Boon or a Curse?
Khanna, A. (2015) · Cancer Research · doi:10.1158/0008-5472.can-14-3247 · Cited by 143
Hypoxia as a biomarker for radioresistant cancer stem cells
Peitzsch, C., Perrin, R. L., Hill, R. P., Dubrovska, A., & Kurth, I. (2014) · International Journal of Radiation Biology · doi:10.3109/09553002.2014.916841 · Cited by 143
Self-citationKim, Y., Lee, Y., Choe, J., Lee, H., Kim, Y., & Jeoung, D. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m708319200 · Cited by 142
Abrogation of radioresistance in glioblastoma stem‐like cells by inhibition of ATM kinase
Carruthers, R., Ahmed, S. U., Strathdee, K. E., Gomez-Roman, N., Amoah-Buahin, E., Watts, C., & Chalmers, A. J. (2014) · Molecular Oncology · doi:10.1016/j.molonc.2014.08.003 · Cited by 139
Chen, L., Guerrero‐Cazares, H., Ye, X., Ford, E., McNutt, T., Kleinberg, L. R., Lim, M. K., Chaichana, K. L., Quiñones‐Hinojosa, A., & Redmond, K. J. (2013) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2013.02.014 · Cited by 137
Yin, H., & Glass, J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024080 · Cited by 135
Yoshimoto, K., Mizoguchi, M., Hata, N., Murata, H., Hatae, R., Amano, T., Nakamizo, A., & Sasaki, T. (2012) · Frontiers in Oncology · doi:10.3389/fonc.2012.00186 · Cited by 126
Evers, P. D., Lee, P. P., DeMarco, J. J., Agazaryan, N., Sayre, J. W., Selch, M. T., & Pajonk, F. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-384 · Cited by 123
Desai, A. B., Webb, B. M., & Gerson, S. L. (2014) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2013.10.040 · Cited by 122
The proportion of stem cells in murine tumors
Hill, R. P., & Milas, L. (1989) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/0360-3016(89)90353-2 · Cited by 116
Findlay, V. J., Wang, C., Watson, D. K., & Camp, E. R. (2014) · Cancer Gene Therapy · doi:10.1038/cgt.2014.15 · Cited by 114
Baumann, M. A., DuBois, W., & Suit, H. D. (1990) · Radiation Research · doi:10.2307/3577740 · Cited by 114
Self-citationChang, C.-W., Chen, Y., Chou, S.-H., Han, C., Chen, Y., Yang, C.-C., Huang, C., & Lo, J. (2014) · Cancer Research · doi:10.1158/0008-5472.can-14-0626 · Cited by 113
Blocking the formation of radiation-induced breast cancer stem cells
Wang, Y., Li, W., Patel, S. S., Cong, J., Zhang, N., Sabbatino, F., Liu, X., Qi, Y., Huang, P., Lee, H., et al. (2014) · Oncotarget · doi:10.18632/oncotarget.1992 · Cited by 109
Cancer stem cell related markers of radioresistance in head and neck squamous cell carcinoma
Kurth, I., Hein, L., Mäbert, K., Peitzsch, C., Koi, L., Cojoc, M., Kunz‐Schughart, L. A., Baumann, M. A., & Dubrovska, A. (2015) · Oncotarget · doi:10.18632/oncotarget.5417 · Cited by 107
Self-citationTumor Cell Radiosensitivity Is a Major Determinant of Tumor Response to Radiation
Gerweck, L. E., Vijayappa, S., Kurimasa, A., Ogawa, K., & Chen, D. J. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-0533 · Cited by 106
Clinical perspectives of cancer stem cell research in radiation oncology
Bütof, R., Dubrovska, A., & Baumann, M. A. (2013) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2013.06.002 · Cited by 100
Self-citationServagi-Vernat, S., Differding, S., Hanin, F., Labar, D., Bol, A., Lee, J. A., & Grégoire, V. (2014) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-014-2730-x · Cited by 100
Hypoxia induces a hedgehog response mediated by HIF‐1α
Bijlsma, M. F., Groot, A. P., Oduro, J. P., Franken, R. J., Schoenmakers, S. H. H. F., Peppelenbosch, M. P., & Spek, C. A. (2008) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2008.00491.x · Cited by 100
CD44: A Cancer Stem Cell–Related Biomarker with Predictive Potential for Radiotherapy
Baumann, M. A., & Krause, M. (2010) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-2244 · Cited by 91
Self-citationCancer stem cells and radiotherapy
Baumann, M. A., Krause, M., Thames, H. D., et al. (2009) · International Journal of Radiation Biology · doi:10.1080/09553000902836404 · Cited by 91
Self-citationEpithelial stem cell mutations that promote squamous cell carcinoma metastasis
White, R. A., Neiman, J. M., Reddi, A. H., Han, G., Birlea, S. A., Mitra, D., Dionne, L., Fernandez, P., Murao, K., Bian, L., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci65856 · Cited by 90
Yaromina, A., Thames, H. D., Zhou, X., Hering, S., Eicheler, W., Dörfler, A., Leichtner, T., Zips, D., & Baumann, M. A. (2010) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2010.04.020 · Cited by 88
Self-citationTinhofer, I., Konschak, R., Stromberger, C., Raguse, J. D., Dreyer, J. H., Jöhrens, K., Keilholz, U., & Budach, V. (2014) · Annals of Oncology · doi:10.1093/annonc/mdu271 · Cited by 87
Lacerda, L., Reddy, J. P., Liu, D., Larson, R. A., Li, L., Masuda, H., Brewer, T. M., Debeb, B. G., Xu, W., Hortobágyi, G. N., et al. (2014) · Stem Cells Translational Medicine · doi:10.5966/sctm.2013-0204 · Cited by 86
Melguizo, C., Prados, J. C., González, B., Ortíz, R., Concha, Á., Alvarez, P. J., Madeddu, R., Perazzoli, G., Oliver, J. A., López, R., et al. (2012) · Journal of Translational Medicine · doi:10.1186/1479-5876-10-250 · Cited by 84
Al‐Assar, O., Demiciorglu, F., Lunardi, S., Gaspar-Carvalho, M. M., McKenna, W. G., Muschel, R. J., & Brunner, T. B. (2014) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2014.03.014 · Cited by 82
The presence of stem cell marker‐expressing cells is not prognostically significant in glioblastomas
Kim, K., Lee, K., Kim, H., Moon, K., Jung, T., Jung, S., & Lee, M. (2011) · Neuropathology · doi:10.1111/j.1440-1789.2010.01194.x · Cited by 80
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Angelastro, J. M., & Lamé, M. W. (2010) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-09-0383 · Cited by 80
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Choi, H., Chun, Y.-S., Kim, T.-Y., & Park, J.-W. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-0505 · Cited by 79
The Proteasome in Cancer Biology and Treatment
Pajonk, F., & McBride, W. H. (2001) · Radiation Research · doi:10.1667/0033-7587(2001)156[0447:tpicba]2.0.co;2 · Cited by 77
Bittner, M.-I., Wiedenmann, N. E., Bucher, S., Hentschel, M., Mix, M. D., Weber, W., & Grosu, A. (2013) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2013.06.012 · Cited by 74
Lagadec, C. H., Vlashi, E., Bhuta, S. M., Lai, C. K., Mischel, P. S., Werner, M., Henke, M., & Pajonk, F. (2014) · BMC Cancer · doi:10.1186/1471-2407-14-152 · Cited by 72
Ball, D., Fisher, R., Burmeister, B. H., Poulsen, M. G., Graham, P., Penniment, M. G., Vinod, S. K., Krawitz, H., Joseph, D. J., Wheeler, G., et al. (2013) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2012.12.003 · Cited by 70
Prediction of response to radiotherapy in the treatment of esophageal cancer using stem cell markers
Smit, J. K., Faber, H., Niemantsverdriet, M., Baanstra, M., Bussink, J., Hollema, H., van Os, R. P., Plukker, J. T. M., & Coppes, R. P. (2013) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2013.03.027 · Cited by 69
Chk1 knockdown confers radiosensitization in prostate cancer stem cells
WANG, X., Ma, Z., XIAO, Z., Liu, H., Dou, Z., Feng, X., & Shi, H. (2012) · Oncology Reports · doi:10.3892/or.2012.2068 · Cited by 66
Influence of Tumor Cell and Stroma Sensitivity on Tumor Response to Radiation
Ogawa, K., Boucher, Y., Kashiwagi, S., Fukumura, D., Chen, D. J., & Gerweck, L. E. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-4498 · Cited by 66
Yaromina, A., Kroeber, T., Meinzer, A., Boeke, S., Thames, H. D., Baumann, M. A., & Zips, D. (2011) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2011.02.015 · Cited by 65
Self-citationZschaeck, S., Haase, R., Abolmaali, N., Perrin, R. L., Stützer, K., Appold, S., Steinbach, J., Kotzerke, J., Zips, D., Richter, C., et al. (2015) · Acta Oncologica · doi:10.3109/0284186x.2015.1074720 · Cited by 64
Self-citationCancer stem cell characteristics of circulating tumor cells
Tinhofer, I., Saki, M. R., Niehr, F., Keilholz, U., & Budach, V. (2014) · International Journal of Radiation Biology · doi:10.3109/09553002.2014.886798 · Cited by 63
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Zhang, Y., & Martin, S. G. (2014) · Clinical Oncology · doi:10.1016/j.clon.2014.02.003 · Cited by 61
Métellus, P., Nanni‐Metellus, I., Delfino, C., Colin, C., Tchogandjian, A., Coulibaly, B., Fina, F., Loundou, A., Barrie, M., Chinot, O. L., et al. (2011) · Annals of Surgical Oncology · doi:10.1245/s10434-011-1703-6 · Cited by 61
Petersen, C., Eicheler, W., Frömmel, A., Krause, M., Balschukat, S., Zips, D., & Baumann, M. A. (2003) · International Journal of Radiation Biology · doi:10.1080/09553000310001609224 · Cited by 60
Self-citationBuffa, F. M., Davidson, S. E., Hunter, R. D., Nahum, A. E., & West, C. (2001) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(01)01584-x · Cited by 58
Rovida, E., Peppicelli, S., Bono, S., Bianchini, F., Tusa, I., Cheloni, G., Marzi, I., Cipolleschi, M. G., Calorini, L., & Sbarba, P. D. (2014) · Cell Cycle · doi:10.4161/15384101.2014.964107 · Cited by 53
Improving external beam radiotherapy by combination with internal irradiation
Dietrich, A., Koi, L., Zöphel, K., Sihver, W., Kotzerke, J., Baumann, M. A., & Krause, M. (2015) · British Journal of Radiology · doi:10.1259/bjr.20150042 · Cited by 49
Self-citationDíaz, R., Nguewa, P., Redrado, M., Manrique, I., & Calvo, A. (2015) · The Prostate · doi:10.1002/pros.22980 · Cited by 38
Characterization of the Stem Cell Niche and Its Importance in Radiobiological Response
Pajonk, F., & Vlashi, E. (2013) · Seminars in Radiation Oncology · doi:10.1016/j.semradonc.2013.05.007 · Cited by 35
Lin, J., Zhang, X., Yang, J., Ye, Y.-B., & Luo, S.-Q. (2010) · Archives of Medical Research · doi:10.1016/j.arcmed.2010.10.006 · Cited by 35
Intratumoral Hypoxia as the Genesis of Genetic Instability and Clinical Prognosis in Prostate Cancer
Taiakina, D., Pra, A. D., & Bristow, R. G. (2013) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-5915-6_9 · Cited by 34
The potential origin of glioblastoma initiating cells
David, A. C. (2011) · Frontiers in Bioscience-Scholar · doi:10.2741/261 · Cited by 33
Bensimon, J., Biard, D. S. F., Paget, V., Goislard, M., Altmeyer‐Morel, S., Konge, J. C., Chevillard, S., & Lebeau, J. (2015) · Molecular Carcinogenesis · doi:10.1002/mc.22273 · Cited by 29
Chen, H., Goodus, M. T., de Toledo, S. M., Azzam, E. I., Levison, S. W., & Souayah, N. (2015) · ASN NEURO · doi:10.1177/1759091415578026 · Cited by 24
Impact of CD133 positive stem cell proportion on survival in patients with glioblastoma multiforme
Kase, M., Minajeva, A., Niinepuu, K., Kase, S., Vardja, M., Asser, T., & Jaal, J. (2013) · Radiology and Oncology · doi:10.2478/raon-2013-0055 · Cited by 20
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Wang, H., Mu, X., He, H., & Zhang, X.-D. (2018) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2017.11.003 · Cited by 572
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Metadata
- Authors
- Krause, M., Dubrovska, A., Linge, A., & Baumann, M.
- Venue
- Advanced Drug Delivery Reviews
- Publisher
- Elsevier BV
- Published
- 2017-01
- Volume
- 109
- Pages
- 63-73
- ISSN
- 0169-409X (ISSN-L)
- OpenAlex
- W2258673083
- Cited by
- 305
- References
- 122
- FWCI
- 4.42
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.