Cited by 268Medication Adherence and ComplianceLipoproteins and Cardiovascular HealthSex and Gender in Healthcare

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Gender and racial disparities in adherence to statin therapy: A meta-analysis

Lewey, Jennifer, Shrank, William H., Bowry, Ashna D.K., Kilabuk, Elaine, Brennan, Troyen A., Choudhry, Niteesh K.·2013·American Heart Journal

DOI 10.1016/j.ahj.2013.02.011

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Abstract

Background Significant disparities exist in cardiovascular outcomes based on race/ethnicity and gender. Rates of evidence-based medication use and long-term medication adherence also appear to be lower in racial subgroups and women but have been subject to little attention. Our objective was to evaluate the effect of race/ethnicity and gender on adherence to statin therapy for primary or secondary prevention. Methods and results Studies were identified through a systematic search of MEDLINE, EMBASE, ClinicalTrials.gov, and the Cochrane Database of Systematic Reviews (through April 1, 2010) and manual examination of references in selected articles. Studies reporting on adherence to statins by men and women or patients of white and nonwhite race were included. Information on study design, adherence measurement, duration, geographic location, sample size, and patient demographics was extracted using a standardized protocol. From 3,022 potentially relevant publications, 53 studies were included. Compared with men, women had a 10% greater odds of nonadherence (odds ratio 1.10, 95% confidence interval [CI], 1.07-1.13). Nonwhite race patients had a 53% greater odds of nonadherence than white race patients (odds ratio 1.53, 95% CI 1.25-1.87). There was significant heterogeneity in the pooled estimate for gender (I(2) 0.95, P value for heterogeneity <.001) and race (I(2) 0.98, P value for heterogeneity <.001). The overall results remained unchanged in those subgroups that had significantly less heterogeneity. Conclusions Among patients prescribed statins, women and nonwhite patients are at increased risk for nonadherence. Further research is needed to identify interventions best suited to improve adherence in these populations.

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Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763
Untitled work
(2014) · Medical Entomology and Zoology · Cited by 17,633
Adherence to medication.
Osterberg, L., & Blaschke, T. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050100 · Cited by 7,974
Unequal treatment: confronting racial and ethnic disparities in health care
(2003) · Choice Reviews Online · doi:10.5860/choice.40-5843 · Cited by 7,043
Heart Disease and Stroke Statistics—2010 Update: A Report From the American Heart Association
WRITING GROUP MEMBERS, Lloyd-Jones, D., Adams, R. J., Brown, T. M., Carnethon, M., Dai, S., De Simone, G., Ferguson, T. B., Ford, E., Furie, K., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.192667 · Cited by 5,700
Health Care Disparities
Capps, L. (2003) · JAMA · doi:10.1001/jama.290.18.2487-b · Cited by 4,558
Explaining the decrease in U.S. deaths from coronary disease, 1980–2000
Ford, E. S., Ajani, U. A., Croft, J. B., Critchley, J. A., Labarthe, D. R., Kottke, T. E., Giles, W. H., & Capewell, S. (2007) · New England Journal of Medicine · doi:10.1056/nejmsa053935 · Cited by 2,757
A systematic review of the associations between dose regimens and medication compliance
Claxton, A. J., Cramer, J., & Pierce, C. (2001) · Clinical Therapeutics · doi:10.1016/s0149-2918(01)80109-0 · Cited by 2,388
Impact of Medication Adherence on Hospitalization Risk and Healthcare Cost
Sokol, M. C., McGuigan, K. A., Verbrugge, R. R., & Epstein, R. S. (2005) · Medical Care · doi:10.1097/01.mlr.0000163641.86870.af · Cited by 1,729
Effect of Statins on Risk of Coronary Disease: A Meta-analysis of Randomized Controlled Trials
LaRosa, J. C., He, J., & Vupputuri, S. (1999) · JAMA · doi:10.1001/jama.282.24.2340 · Cited by 1,246
Long-term persistence in use of statin therapy in elderly patients
Benner, J. S. (2002) · JAMA · doi:10.1001/jama.288.4.455 · Cited by 1,232
Effect of Medication Nonadherence on Hospitalization and Mortality Among Patients With Diabetes Mellitus
Ho, P. M., Rumsfeld, J. S., Masoudi, F. A., McClure, D. L., Plomondon, M. E., Steiner, J. F., & Magid, D. J. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.17.1836 · Cited by 1,135
Adherence with statin therapy in elderly patients with and without acute coronary syndromes
Jackevicius, C. A. (2002) · JAMA · doi:10.1001/jama.288.4.462 · Cited by 1,077
Relationship between adherence to evidence-based pharmacotherapy and long-term mortality after acute myocardial infarction
Rasmussen, J. N., Chong, A., & Alter, D. A. (2007) · JAMA · doi:10.1001/jama.297.2.177 · Cited by 975
Thirty-Day Readmission Rates for Medicare Beneficiaries by Race and Site of Care
Joynt, K. E. (2011) · JAMA · doi:10.1001/jama.2011.123 · Cited by 729
Impact of Medication Therapy Discontinuation on Mortality After Myocardial Infarction
Ho, P. M., Spertus, J. A., Masoudi, F. A., Reid, K. J., Peterson, E. D., Magid, D. J., Krumholz, H. M., & Rumsfeld, J. S. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.17.1842 · Cited by 635
Persistence of Use of Lipid-Lowering Medications
Avorn, J., Monette, J., Lacour, A. S., Bohn, R. L., Monane, M., Mogun, H., & LeLorier, J. (1998) · JAMA · doi:10.1001/jama.279.18.1458 · Cited by 635
Hospital Admissions Resulting from Preventable Adverse Drug Reactions
Mcdonnell, P. J., & Jacobs, M. R. (2002) · Annals of Pharmacotherapy · doi:10.1345/aph.1a333 · Cited by 573
Racial Variation in the Use of Coronary-Revascularization Procedures — Are the Differences Real? Do They Matter?
Peterson, E. D., Shaw, L. K., DeLong, E. R., Pryor, D. B., Califf, R. M., & Mark, D. B. (1997) · New England Journal of Medicine · doi:10.1056/nejm199702133360706 · Cited by 550
Comparing Adherence and Persistence Across 6 Chronic Medication Classes
Yeaw, J., Benner, J. S., Walt, J. G., Sian, S., & Smith, D. B. (2009) · Journal of Managed Care Pharmacy · doi:10.18553/jmcp.2009.15.9.728 · Cited by 549
Sex and Racial Differences in the Management of Acute Myocardial Infarction, 1994 through 2002
Vaccarino, V., Rathore, S. S., WENGER, N. K., Frederick, P. D., Abramson, J. L., Barron, H. V., Manhapra, A., Mallik, S., & Krumholz, H. M. (2005) · New England Journal of Medicine · doi:10.1056/nejmsa032214 · Cited by 544
Predictors of Adherence With Antihypertensive and Lipid-Lowering Therapy
Chapman, R. H. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.10.1147 · Cited by 506
Prevalence, Predictors, and Outcomes of Primary Nonadherence After Acute Myocardial Infarction
Jackevicius, C. A., Li, P., & Tu, J. V. (2008) · Circulation · doi:10.1161/circulationaha.107.706820 · Cited by 481
Thinking Outside the Pillbox — Medication Adherence as a Priority for Health Care Reform
Cutler, D., & Everett, W. (2010) · New England Journal of Medicine · doi:10.1056/nejmp1002305 · Cited by 459
Trends in the Quality of Care and Racial Disparities in Medicare Managed Care
Trivedi, A. N., Zaslavsky, A. M., Schneider, E. C., & Ayanian, J. Z. (2005) · New England Journal of Medicine · doi:10.1056/nejmsa051207 · Cited by 369
Twelve-Year Follow-Up of American Women’s Awareness of Cardiovascular Disease Risk and Barriers to Heart Health
Mosca, L. J., Greenberger, H. M., Dolor, R. J., Newby, L. K., & Robb, K. J. (2010) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.109.915538 · Cited by 368
Interventions to improve adherence to lipid-lowering medication
van Driel, M. L., Morledge, M. D., Ulep, R., Shaffer, J. P., Davies, P., & Deichmann, R. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004371.pub4 · Cited by 333
Health Care for Black and Poor Hospitalized Medicare Patients
Kahn, K. L. (1994) · JAMA · doi:10.1001/jama.1994.03510390039027 · Cited by 331
Predictors of Nonadherence to Statins: A Systematic Review and Meta-Analysis
Mann, D. M., Woodward, M., Muntner, P., Falzon, L., & Kronish, I. (2010) · Annals of Pharmacotherapy · doi:10.1345/aph.1p150 · Cited by 329
Suboptimal statin adherence and discontinuation in primary and secondary prevention populations
Ellis, J. J., Erickson, S. R., Stevenson, J. G., Bernstein, S. J., Stiles, R. A., & Fendrick, A. M. (2004) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2004.30516.x · Cited by 320
Antidepressant-Induced Sexual Dysfunction
Gregorian, R. S., Golden, K. A., Bahce, A., Goodman, C., Kwong, W. J., & Khan, Z. M. (2002) · Annals of Pharmacotherapy · doi:10.1345/aph.1a195 · Cited by 320
Differences in control of cardiovascular disease and diabetes by race, ethnicity, and education: U.S. trends from 1999 to 2006 and effects of medicare coverage
McWilliams, J. M., Meara, E., Zaslavsky, A. M., & Ayanian, J. Z. (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-150-8-200904210-00005 · Cited by 315
The Implications of Therapeutic Complexity on Adherence to Cardiovascular Medications
Choudhry, N. K., Fischer, M. A., Avorn, J., Liberman, J. N., Schneeweiß, S., Pakes, J., Brennan, T. A., & Shrank, W. H. (2011) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.495 · Cited by 314
Self-citation
The Role Of Health Insurance Coverage In Reducing Racial/Ethnic Disparities In Health Care
Lillie-Blanton, M., & Hoffman, C. (2005) · Health Affairs · doi:10.1377/hlthaff.24.2.398 · Cited by 308
Racial and Ethnic Differences in Time to Acute Reperfusion Therapy for Patients Hospitalized With Myocardial Infarction
Bradley, E. H. (2004) · JAMA · doi:10.1001/jama.292.13.1563 · Cited by 287
Long-term adherence with cardiovascular drug regimens
Kulkarni, S. P., Alexander, K. P., Lytle, B. L., HEISS, G. M., & Peterson, E. D. (2005) · American Heart Journal · doi:10.1016/j.ahj.2005.02.038 · Cited by 242
Sex Differences in Mortality After Acute Myocardial Infarction
Vaccarino, V., Parsons, L. S., Peterson, E. D., Rogers, W. J., Kiefe, C. I., & Canto, J. G. (2009) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.332 · Cited by 235
Racial Variations in Treatment and Outcomes of Black and White Patients With High-Risk Non–ST-Elevation Acute Coronary Syndromes
Sonel, A. F., Good, C. B., Mulgund, J., Roe, M. T., Gibler, W. B., Smith, S. C., Cohen, M. G., Pollack, C. V., Ohman, E. M., & Peterson, E. D. (2005) · Circulation · doi:10.1161/01.cir.0000157732.03358.64 · Cited by 231
Adherence to evidence-based therapies after discharge for acute coronary syndromes: an ongoing prospective, observational study
Eagle, K. A., Kline-Rogers, E. M., Goodman, S. G., Gurfinkel, E., Avezum, Á., Flather, M. D., Granger, C. B., Erickson, S. R., White, K., & Steg, P. G. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2003.12.041 · Cited by 230
Patient, Physician, and Payment Predictors of Statin Adherence
Chan, D. C., Shrank, W. H., Cutler, D., Jan, S., Fischer, M. A., Liu, J., Avorn, J., Solomon, D. H., Brookhart, M. A., & Choudhry, N. K. (2010) · Medical Care · doi:10.1097/mlr.0b013e3181c132ad · Cited by 184
Self-citation
Long-term Medication Adherence after Myocardial Infarction: Experience of a Community
Shah, N. D., Dunlay, S. M., Ting, H. H., Montori, V. M., Thomas, R. J., Wagie, A. E., & Roger, V. L. (2009) · The American Journal of Medicine · doi:10.1016/j.amjmed.2008.12.021 · Cited by 179
Race and sex differences in the management of coronary artery disease
Sheifer, S. E., Escarce, J. J., & Schulman, K. A. (2000) · American Heart Journal · doi:10.1016/s0002-8703(00)90017-6 · Cited by 170
Statin induced myopathy
Sathasivam, S., & Lecky, B. R. F. (2008) · BMJ · doi:10.1136/bmj.a2286 · Cited by 164
Effects of Increased Patient Cost Sharing on Socioeconomic Disparities in Health Care
Chernew, M. E., Gibson, T. B., Yu-Isenberg, K. S., Sokol, M. C., Rosen, A. B., & Fendrick, A. M. (2008) · Journal of General Internal Medicine · doi:10.1007/s11606-008-0614-0 · Cited by 160
Interventions to improve adherence to lipid lowering medication
Schedlbauer, A., Davies, P. A., & Fahey, T. P. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004371.pub3 · Cited by 152
Persistence and determinants of statin therapy among middle‐aged patients for primary and secondary prevention
Perreault, S., Blais, L., Lamarre, D., Dragomir, A., Berbiche, D., Lalonde, L., Laurier, C., St-Maurice, F., & Collin, J. (2005) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2005.02355.x · Cited by 146
Long-term persistence with statin treatment in a not-for-profit health maintenance organization: a population-based retrospective cohort study in Israel
Chodick, G., Shalev, V., Gerber, Y., Heymann, A. D., Silber, H., Simah, V., & Kokia, E. (2008) · Clinical Therapeutics · doi:10.1016/j.clinthera.2008.11.012 · Cited by 145
Predictors of medication nonadherence among patients with diabetes in Medicare Part D programs: A retrospective cohort study
Yang, Y., Thumula, V., Pace, P. F., Banahan, B. F., Wilkin, N. E., & Lobb, W. B. (2009) · Clinical Therapeutics · doi:10.1016/j.clinthera.2009.10.002 · Cited by 143
Adherence to Statin Therapy Under Drug Cost Sharing in Patients With and Without Acute Myocardial Infarction
Schneeweiß, S., Patrick, A. R., Maclure, M., Dormuth, C. R., & Glynn, R. J. (2007) · Circulation · doi:10.1161/circulationaha.106.665992 · Cited by 132
Differences in Mortality and Use of Revascularization in Black and White Patients With Acute MI Admitted to Hospitals With and Without Revascularization Services
Popescu, I., Vaughan‐Sarrazin, M., & Rosenthal, G. E. (2007) · JAMA · doi:10.1001/jama.297.22.2489 · Cited by 123
Adherence to statins, beta-blockers and angiotensin-converting enzyme inhibitors following a first cardiovascular event: a retrospective cohort study.
Blackburn, D. F., Dobson, R. T., Blackburn, J. L., Wilson, T. W., Stang, M. R., & Semchuk, W. (2005) · PubMed · Cited by 122
Race, ethnicity, and sociocultural characteristics predict noncompliance with lipid-lowering medications
Kaplan, R. C., Bhalodkar, N. C., Brown, E. J., White, J. R., & Brown, D. L. (2004) · Preventive Medicine · doi:10.1016/j.ypmed.2004.04.041 · Cited by 121
Factors Related to Adherence to Statin Therapy
McGinnis, B., Olson, K. L., Magid, D. J., Bayliss, E., Korner, E. J., Brand, D. W., & Steiner, J. F. (2007) · Annals of Pharmacotherapy · doi:10.1345/aph.1k209 · Cited by 121
Predictors of Adherence to Concomitant Antihypertensive and Lipid-Lowering Medications in Older Adults
Chapman, R. H., Petrilla, A. A., Benner, J. S., Schwartz, J. S., & Tang, S. S. K. (2008) · Drugs & Aging · doi:10.2165/00002512-200825100-00008 · Cited by 121
Statin induced myopathy.
Frank, R. E. (2009) · PubMed · Cited by 120
Racial differences in adherence to cardiac medications.
Charles, H., Good, C. B., Hanusa, B. H., Chang, C. H., & Whittle, J. (2003) · PubMed Central · Cited by 120
At Pitney Bowes, Value-Based Insurance Design Cut Copayments And Increased Drug Adherence
Choudhry, N. K., Fischer, M. A., Avorn, J., Schneeweiß, S., Solomon, D. H., Berman, C., Jan, S., Liu, J., Lii, J., Brookhart, M. A., et al. (2010) · Health Affairs · doi:10.1377/hlthaff.2010.0336 · Cited by 115
Self-citation
Follow-up lipid tests and physician visits are associated with improved adherence to statin therapy
Benner, J. S., Tierce, J. C., Ballantyne, C. M., Prasad, C., Bullano, M. F., Willey, V. J., Erbey, J., & Sugano, D. S. (2004) · PharmacoEconomics · doi:10.2165/00019053-200422003-00003 · Cited by 115
Factors affecting patient compliance with antihyperlipidemic medications in an HMO population.
Sung, J. C., Nichol, M. B., Venturini, F., Bailey, K. L., McCombs, J. S., & Cody, M. (1998) · PubMed · Cited by 111
Impact of statin copayments on adherence and medical care utilization and expenditures.
Gibson, T. B., Mark, T. L., Axelsen, K. J., Baser, O., Rublee, D. A., & McGuigan, K. A. (2006) · PubMed · Cited by 110
Determinants of compliance with statin therapy and low-density lipoprotein cholesterol goal attainment in a managed care population.
Schultz, J. S., O’Donnell, J. C., McDonough, K. L., Sasané, R., & Meyer, J. W. (2005) · PubMed · Cited by 107
Predictors of Early Discontinuation of Evidence-Based Medicine After Acute Coronary Syndrome
Melloni, C., Alexander, K. P., Ou, F., LaPointe, N. M. A., Roe, M. T., Newby, L. K., Baloch, K. N., Ho, P. M., Rumsfeld, J. S., & Peterson, E. D. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.03.013 · Cited by 102
Impact of better adherence to statin agents in the primary prevention of coronary artery disease
Perreault, S., Dragomir, A., Blais, L., Bérard, A., Lalonde, L., White, M., & Pilon, D. (2009) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-009-0673-0 · Cited by 96
The Coalition to Reduce Racial and Ethnic Disparities in Cardiovascular Disease Outcomes (credo)
Yancy, C. W., Wang, T. Y., Ventura, H. O., Piña, I. L., Vijayaraghavan, K., Ferdinand, K. C., & Hall, L. L. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.09.027 · Cited by 94
Modes of delivery for interventions to improve cardiovascular medication adherence.
Cutrona, S. L., Choudhry, N. K., Fischer, M. A., Servi, A. D., Liberman, J. N., Brennan, T. A., & Shrank, W. H. (2010) · PubMed · Cited by 94
Self-citation
Racial differences in long-term adherence to oral antidiabetic drug therapy: a longitudinal cohort study
Trinacty, C. M., Adams, A. S., Soumerai, S. B., Zhang, F., Meigs, J. B., Piette, J. D., & Ross‐Degnan, D. (2009) · BMC Health Services Research · doi:10.1186/1472-6963-9-24 · Cited by 93
Compliance with a statin treatment in a usual-care setting:Retrospective database analysis over 3 years after treatment initiation in health maintenance organization enrollees with dyslipidemia
Caspard, H., Chan, K. A., & Walker, A. M. (2005) · Clinical Therapeutics · doi:10.1016/j.clinthera.2005.10.005 · Cited by 92
Results of a retrospective database analysis of adherence to statin therapy and risk of nonfatal ischemic heart disease in daily clinical practice in Italy
Corrao, G., Conti, V., Merlino, L. G., Catapano, A. L., & Mancia, G. (2010) · Clinical Therapeutics · doi:10.1016/j.clinthera.2010.02.004 · Cited by 91
Long‐term adherence to statin treatment in diabetes
Donnelly, L. A., Doney, A. S. F., Morris, A. D., Palmer, C. N. A., & Donnan, P. T. (2008) · Diabetic Medicine · doi:10.1111/j.1464-5491.2008.02476.x · Cited by 84
Long-term persistence with statin therapy: A nationwide register study in Finland
Helin-Salmivaara, A., Lavikainen, P., Korhonen, M. J., Halava, H., Junnila, S. Y. T., Kettunen, R., Neuvonen, P. J., Martikainen, J. E., Ruokoniemi, P., & Saastamoinen, L. K. (2008) · Clinical Therapeutics · doi:10.1016/j.clinthera.2008.12.003 · Cited by 76
Association between short-term effectiveness of statins and long-term adherence to lipid-lowering therapy
Benner, J. S., Pollack, M. F., Smith, T. W., Bullano, M. F., Willey, V. J., & Williams, S. A. (2005) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp040419 · Cited by 70
Individualising the risks of statins in men and women in England and Wales: population-based cohort study
Hippisley‐Cox, J., & Coupland, C. A. C. (2010) · Heart · doi:10.1136/hrt.2010.199034 · Cited by 68
Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular disease
Perreault, S., Blais, L., Dragomir, A., Bouchard, M.-H., Lalonde, L., Laurier, C., & Collin, J. (2005) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-005-0980-z · Cited by 67
Site of medical care: do racial and ethnic differences persist?
Lillie-Blanton, M., Martinez, R. M., & Salganicoff, A. N. (2001) · PubMed · Cited by 65
Medication Adherence Following Coronary Artery Bypass Graft Surgery: Assessment of Beliefs and Attitudes
Khanderia, U., Townsend, K., Erickson, S. R., Vlasnik, J. J., Prager, R. L., & Eagle, K. A. (2008) · Annals of Pharmacotherapy · doi:10.1345/aph.1k497 · Cited by 64
Adherence with statins over 8 years in a usual care setting.
Vinker, S., Shani, M., Baevsky, T., & Elhayany, A. (2008) · PubMed · Cited by 62
Impact of prescription size on statin adherence and cholesterol levels
Batal, H. A., Krantz, M. J., Dale, R. A., Mehler, P. S., & Steiner, J. F. (2007) · BMC Health Services Research · doi:10.1186/1472-6963-7-175 · Cited by 62
Association between copayment and adherence to statin treatment initiated after coronary heart disease hospitalization: A longitudinal, retrospective, cohort study
YE, X., GROSS, C., Schommer, J. C., Cline, R. R., & Peter, W. L. S. (2007) · Clinical Therapeutics · doi:10.1016/j.clinthera.2007.12.022 · Cited by 61
RACIAL VARIATION IN THE USE OF CORONARY-REVASCULARIZATION PROCEDURES
Ric, E., Eterson, D. P., Haw, L. I. K. S., Ong, E. L., Ryor, D. A. B. P., Aliff, R. O. M. C., & Ark, D. A. B. M. (2008) · Cited by 61
Analysis of Factors Associated With Statin Adherence in a Hierarchical Model Considering Physician,Pharmacy, Patient, and Prescription Characteristics
Pedan, A., Varasteh, L. T., & Schneeweiß, S. (2007) · Journal of Managed Care Pharmacy · doi:10.18553/jmcp.2007.13.6.487 · Cited by 60
Healthcare information technology interventions to improve cardiovascular and diabetes medication adherence.
Misono, A. S., Cutrona, S. L., Choudhry, N. K., Fischer, M. A., Stedman, M. R., Liberman, J. N., Brennan, T. A., JAIN, S. H., & Shrank, W. H. (2010) · PubMed · Cited by 59
Self-citation
Compliance with Fluvastatin Treatment Characterization of the Noncompliant Population within a Population of 3845 Patients with Hyperlipidemia
Bruckert, É., Simonetta, C., & Giral, P. (1999) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(99)00019-0 · Cited by 51
Statin adherence and mortality in patients enrolled in a secondary prevention program.
McGinnis, B., Olson, K. L., Delate, T., & Stolcpart, R. S. (2009) · PubMed · Cited by 49
Association between adherence to statin therapy and lipid control in Hong Kong Chinese patients at high risk of coronary heart disease
Cheng, C. W. R., Woo, K.-S., Chan, J. C. N., Tomlinson, B., & You, J. H. S. (2004) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2004.02202.x · Cited by 46
Recognizing and Improving Health Care Disparities in the Prevention of Cardiovascular Disease in Women
Jarvie, J. L., & Foody, J. M. (2010) · Current Cardiology Reports · doi:10.1007/s11886-010-0135-4 · Cited by 46
Discontinuation and switching of therapy after initiation of lipid‐lowering drugs: the effects of comorbidities and patient characteristics
Yang, C., Jick, S. S., & Testa, M. A. (2003) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.2003.01818.x · Cited by 44
Persistence of atorvastatin and simvastatin among patients with and without prior cardiovascular diseases: a US managed care study
Foody, J. M., Joyce, A. T., Rudolph, A. E., Liu, L. Z., & Benner, J. S. (2008) · Current Medical Research and Opinion · doi:10.1185/03007990802203279 · Cited by 43
Racial differences in reaching target low-density lipoprotein goal among individuals treated with prescription statin therapy
Yood, M. U., McCarthy, B. D., Kempf, J., Kucera, G. P., Wells, K. E., Oliveria, S. A., & Stang, P. (2006) · American Heart Journal · doi:10.1016/j.ahj.2006.02.036 · Cited by 43
Parabolas of medication use and discontinuation after myocardial infarction—are we closing the treatment gap?
Hudson, M., Richard, H., & Pilote, L. (2007) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.1414 · Cited by 42
Effectiveness of two statin prescribing strategies with respect to adherence and cardiovascular outcomes: observational study
Li, W., MacDonald, T. M., Watson, A., & Murphy, M. J. (2006) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.1297 · Cited by 41
Adherence to statin therapy and patients’ cardiovascular risk: a pharmacoepidemiological study in Italy
Poluzzi, E., Strahinja, P., Lanzoni, M., Vargiu, A., Silvani, M. C., Motola, D., Gaddi, A. V., Vaccheri, A., & Montanaro, N. (2008) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-007-0428-8 · Cited by 40
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Abraha, I., Montedori, A., Stracci, F., Rossi, M., & Romagnoli, C. (2003) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-003-0675-2 · Cited by 40
Efficacy of intradialytic parenteral nutrition in malnourished hemodialysis patients
Cherry, N., & Shalansky, K. (2002) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/59.18.1736 · Cited by 35
Delay in filling the initial prescription for a statin: A potential early indicator of medication nonpersistence
Yu, A. P., Yu, Y., Nichol, M. B., & Gwadry-Sridhar, F. H. (2008) · Clinical Therapeutics · doi:10.1016/j.clinthera.2008.04.015 · Cited by 24
Association of medical noncompliance and long-term adverse outcomes, after myocardial infarction in a minority and uninsured population
Amin, A. P., Mukhopadhyay, E., Nathan, S., Napan, S., & Kelly, R. F. (2009) · Translational research · doi:10.1016/j.trsl.2009.05.004 · Cited by 21
Adherence-adjusted efficacy with intensive versus standard statin therapy in patients with acute myocardial infarction in the IDEAL study
Holme, I., Szarek, M. J., Cater, N. B., Færgeman, O., Kastelein, J. J. P., OLSSON, A. G., Tikkanen, M. J., Larsen, M. L., Lindahl, C., Pedersen, T. R., et al. (2009) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e32832130f5 · Cited by 19
Adherence to Lipid-Lowering Drug Therapy among Members of the Canadian Forces
Ma, J., Vaillancourt, R., & Bennett, C. L. (2008) · Military Medicine · doi:10.7205/milmed.173.7.666 · Cited by 3

Research works printed but not linked: 1

Shalansky, 2002, Effect of number of medications on cardiovascular therapy adherence, Ann Pharmacother, 36, 1532, 10.1345/aph.1C044 · DOI · Paper page

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See all 268

Authors: Lewey, J., Shrank, W. H., Bowry, A. D. K., Kilabuk, E., Brennan, T. A., & Choudhry, N. K.
Affiliations: Brigham and Women's Hospital (US)
St. Michael's Hospital (CA)
CVS Health (United States) (US)
Corresponding author: Choudhry, Niteesh K.
ORCID: Lewey, Jennifer
Choudhry, Niteesh K.
Venue: American Heart Journal
Publisher: Elsevier BV
Published: 2013-05
Volume: 165
Issue: 5
Pages: 665-678.e1
ISSN: 0002-8703 (ISSN-L)
DOI: 10.1016/j.ahj.2013.02.011
OpenAlex: W2100554124
Cited by: 267
References: 98
Citations by year: 2026: 14 · 2025: 22 · 2024: 17 · 2023: 13 · 2022: 26 · 2021: 26 · 2020: 27 · 2019: 21 · 2018: 16 · 2017: 21 · 2016: 22 · 2015: 20 · 2014: 19 · 2013: 3
FWCI: 2.82
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: American Heart Journal (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
Keywords: statin therapy, medication adherence, non-compliance, gender disparities, racial disparities, ethnic minorities, women, cardiovascular disease prevention, secondary prevention, health disparities
MeSH terms: Cardiovascular Diseases, Humans, Morbidity, Sex Factors, Global Health, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Racial Groups, Medication Adherence

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Gender and racial disparities in adherence to statin therapy: A meta-analysis

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