Advanced anterior vaginal wall prolapse is highly correlated with apical prolapse
Abstract
Objective The purpose of this study was to determine the relationship between the most prolapsed portion of the anterior and posterior vaginal walls and the apex.Study design After obtaining institutional review board approval, demographic data and pelvic organ prolapse quantification findings from consecutive new patients who were seen at our urogynecologic practice between January 2004 and February 2005 were reviewed.Results Three hundred twenty-five women were included in this cohort. The support of the vaginal apex (pelvic organ prolapse quantification point C) correlated strongly with the most prolapsed portion of the anterior vaginal wall, Ba (Spearman's rho = 0.835; P < .001) and correlated moderately with the most prolapsed portion of the posterior vaginal wall, Bp (Spearman's rho = 0.556; P < .001). A strong linear relationship was found between C and Ba, which is best modeled by the following regression equation: C = Ba(1.4) - 4.4 (r = .869).Conclusion Anterior vaginal wall prolapse is associated strongly with apical prolapse. Anterior vaginal wall defects that are surgically repaired usually require a concomitant repair of the apex.
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Recurrence at the same site may be because the primary surgery did not address the underlying neuromuscular and connective tissue dysfunction responsible for the primary prolapse.
“The recurrence at the same site may be because the primary surgery to correct the anatomical defect may not have taken care of the underlying neuromuscular and connective tissue dysfunction that was responsible for the primary prolapse and this could have played a significant role in the recurrence [8, 28].”
From Risk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort study (2022) · cites this paper as [28]
The preferred surgical approach for uterine prolapse amongst many urogynaecologists remains vaginal hysterectomy with apical suspension.
“The preferred surgical approach for uterine prolapse amongst many urogynaecologists remains vaginal hysterectomy (VH) with apical suspension [3], recognising the association between the more common anterior wall prolapse and apical descent [3, 4].”
From Laparoscopic sacrohysteropexy versus vaginal hysterectomy and apical suspension: 7-year follow-up of a randomized controlled trial (2022) · cites this paper as [4]
Cites
The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction
Bump, R. C., Mattiasson, A., Bø, K., Brubaker, L. P., DeLancey, J. O. L., Klarskov, P., Shull, B. L., & Smith, A. R. B. (1996) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(96)70243-0 · Cited by 4,275 · see citing works
Self-citationEpidemiology of surgically managed pelvic organ prolapse and urinary incontinence
OLSEN, A., SMITH, V, BERGSTROM, J., COLLING, J., & CLARK, A. (1997) · Obstetrics & Gynecology · doi:10.1016/s0029-7844(97)00058-6 · Cited by 3,335 · see citing works
Swift, S., Woodman, P., O'Boyle, A., Kahn, M., Valley, M., Bland, D., Wang, W., & Schaffer, J. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.10.602 · Cited by 752 · see citing works
Barber, M. D., Kuchibhatla, M. N., Pieper, C. F., & Bump, R. C. (2001) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2001.118659 · Cited by 617 · see citing works
Procedures for pelvic organ prolapse in the United States, 1979-1997
Boyles, S. H., Weber, A. M., & Meyn, L. (2003) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2003.101 · Cited by 501 · see citing works
Cost of pelvic organ prolapse surgery in the United States
Subak, L. L. (2001) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(01)01472-7 · Cited by 495 · see citing works
A new look at pelvic relaxation
Richardson, A. C., Lyon, J. B., & Williams, N. L. (1976) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(76)90751-1 · Cited by 380 · see citing works
Risk factors for prolapse recurrence after vaginal repair
Whiteside, J. L., Weber, A. M., Meyn, L. A., & Walters, M. D. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.06.109 · Cited by 329 · see citing works
Clark, A. L., Gregory, T., Smith, V. J., & Edwards, R. (2003) · American Journal of Obstetrics and Gynecology · doi:10.1067/s0002-9378(03)00829-9 · Cited by 290 · see citing works
Pelvic organ prolapse surgery in the United States, 1997
Brown, J. S., Waetjen, L. E., Subak, L. L., Thom, D. H., Eeden, S. K. V. D., & Vittinghoff, E. (2002) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2002.121897 · Cited by 245 · see citing works
Risk Factors for Prolapse Recurrence After Vaginal Repair
Whitesides, J. L., Weber, A. M., Meyn, L. A., & Walters, M. D. (2005) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000154427.36673.90 · Cited by 37 · see citing works
A comparison of women with primary and recurrent pelvic prolapse
Kenton, K. S., Sadowski, D. L., Shott, S., & Brubaker, L. T. (1999) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(99)70027-x · Cited by 33 · see citing works
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Outcomes of Vaginal Prolapse Surgery Among Female Medicare Beneficiaries: The Role of Apical Support
Eilber, K. S., Alperin, M., Khan, A., Wu, N., Pashos, C. L., Clemens, J. Q., & Anger, J. T. (2013) · Obstetrics & Gynecology · doi:10.1097/aog.0b013e3182a8a5e4 · Cited by 177 · see citing works
What's new in the functional anatomy of pelvic organ prolapse?
DeLancey, J. O. L. (2016) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000312 · Cited by 159 · see citing works
Genital hiatus size is associated with and predictive of apical vaginal support loss
Lowder, J. L., Oliphant, S. S., Shepherd, J. P., Ghetti, C., & Sutkin, G. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.12.027 · Cited by 83 · see citing works
Surgical interventions for uterine prolapse and for vault prolapse: the two VUE RCTs
Hemming, C., Constable, L., Goulao, B., Kilonzo, M., Boyers, D., Elders, A., Cooper, K., Smith, A., Freeman, R., Breeman, S., et al. (2020) · Health Technology Assessment · doi:10.3310/hta24130 · Cited by 35 · see citing works
Siahkal, S. F., Iravani, M., Mohaghegh, Z., Sharifipour, F., Zahedian, M., & Nasab, M. B. (2021) · International Urogynecology Journal · doi:10.1007/s00192-020-04639-0 · Cited by 33 · see citing works
Consistently inconsistent, the posterior vaginal wall
Hale, D. S., & Fenner, D. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.09.001 · Cited by 26 · see citing works
Izett-Kay, M. L., Rahmanou, P., Cartwright, R. J., Price, N., & Jackson, S. R. (2022) · International Urogynecology Journal · doi:10.1007/s00192-021-04932-6 · Cited by 26 · see citing works
Risk factors for vaginal mesh erosion after sacrocolpopexy in Korean women
Kim, T. Y., & Jeon, M. J. (2020) · PLOS ONE · doi:10.1371/journal.pone.0228566 · Cited by 18 · see citing works
Kayondo, M., Geissbüehler, V., Migisha, R., Kajabwangu, R., Njagi, J., Kato, P. K., Fajardo, Y., Lugobe, H. M., & Kaye, D. K. (2022) · International Urogynecology Journal · doi:10.1007/s00192-021-04930-8 · Cited by 15 · see citing works
DeLancey, J. O. L., Mastrovito, S., Masteling, M., Hong, C. X., Ashton-Miller, J. A., & Chen, L. (2025) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2025.01.011 · Cited by 13 · see citing works
Pelvic organ prolapse recurrence after apical prolapse repair: does obesity matter?
Metcalfe, N. D., Shandley, L. M., Young, M. R., Higgins, M., Abanulo, C., & Northington, G. M. (2022) · International Urogynecology Journal · doi:10.1007/s00192-021-04806-x · Cited by 8 · see citing works
Hafedh, B., Idris, S., Nadreen, F., Banasser, A., Iskandarani, R., & Baradwan, S. (2024) · International Journal of Women's Health · doi:10.2147/ijwh.s474835 · Cited by 1 · see citing works
Maher, C. (2021) · Pelvic Floor Disorders · doi:10.1007/978-3-030-40862-6_55 · Cited by 1 · see citing works
- Authors
- Rooney, K., Kenton, K., Mueller, E. R., FitzGerald, M. P., & Brubaker, L.
- Affiliations
- Loyola University Medical Center (US)
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2006-12
- Volume
- 195
- Issue
- 6
- Pages
- 1837-1840
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W1988929526
- Cited by
- 281
- References
- 12
- Citations by year
- 2026: 12 · 2025: 10 · 2024: 10 · 2023: 16 · 2022: 18 · 2021: 18 · 2020: 25 · 2019: 11 · 2018: 19 · 2017: 27 · 2016: 22 · 2015: 12 · 2014: 19 · 2013: 16 · 2012: 14
- FWCI
- 2.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Keywords
- cystocele, apical prolapse, POP-Q, posterior vaginal wall prolapse, pelvic organ prolapse, surgical repair, urogynecology
- MeSH terms
- Adult, Aged, Aged, 80 and over, Female, Humans, Medical Records, Middle Aged, Physical Examination, Severity of Illness Index, Uterine Prolapse, Vagina, Cohort Studies, Linear Models
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