Proteomic and biophysical analyses reveal a metabolic shift in nitrogen deprived Nannochloropsis oculata

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Bligh, E. G., & Dyer, W. J. (1959) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/o59-099 · Cited by 54,751 · see citing works

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Bligh, E. G., & Dyer, W. J. (1959) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/y59-099 · Cited by 23,189 · see citing works

Studies of marine planktonic diatoms. I. Cyclotella nana Hustedt, and Detonula confervacea (cleve) Gran.

Guillard, R. R., & Ryther, J. (1962) · Canadian Journal of Microbiology (print) · doi:10.1139/m62-029 · Cited by 7,663 · see citing works

Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search.

Keller, A., Nesvizhskii, A., Kolker, E., & Aebersold, R. (2002) · Analytical Chemistry · doi:10.1021/ac025747h · Cited by 4,970 · see citing works

A statistical model for identifying proteins by tandem mass spectrometry.

Nesvizhskii, A., Keller, A., Kolker, E., & Aebersold, R. (2003) · Analytical Chemistry · doi:10.1021/ac0341261 · Cited by 4,902 · see citing works

Microalgal triacylglycerols as feedstocks for biofuel production: perspectives and advances

Hu, Q., Sommerfeld, M., Jarvis, E., Ghirardi, M., Posewitz, M., Seibert, M., & Darzins, A. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03492.x · Cited by 3,745 · see citing works

Microalgae for oil: Strain selection, induction of lipid synthesis and outdoor mass cultivation in a low-cost photobioreactor

Rodolfi, L., Chini Zittelli, G., Bassi, N., Padovani, G., Biondi, N., Bonini, G., & Tredici, M. R. (2009) · Biotechnology and Bioengineering · doi:10.1002/bit.22033 · Cited by 2,879 · see citing works

An outlook on microalgal biofuels

Wijffels, R. H., & Barbosa, M. J. (2010) · Science · doi:10.1126/science.1189003 · Cited by 1,886 · see citing works

Effect of temperature and nitrogen concentration on the growth and lipid content of Nannochloropsis oculata and Chlorella vulgaris for biodiesel production

Converti, A., Casazza, A. A., Ortiz, E. Y., Perego, P., & Del Borghi, M. (2009) · Chemical Engineering and Processing: Process Intensification · doi:10.1016/j.cep.2009.03.006 · Cited by 1,466 · see citing works

Lipid productivity as a key characteristic for choosing algal species for biodiesel production

Griffiths, M. J., & Harrison, S. T. L. (2009) · Journal of Applied Phycology · doi:10.1007/s10811-008-9392-7 · Cited by 1,421 · see citing works

Respiratory metabolism: glycolysis, the TCA cycle and mitochondrial electron transport

Fernie, A. R., Carrari, F., & Sweetlove, L. J. (2004) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2004.03.007 · Cited by 1,403 · see citing works

CO2 in Seawater: Equilibrium, Kinetics, Isotopes

Delille, B. (2002) · Journal of Marine Systems · doi:10.1016/s0924-7963(02)00179-3 · Cited by 1,298 · see citing works

Effects of nitrogen sources on cell growth and lipid accumulation of green alga Neochloris oleoabundans

Li, Y., Horsman, M., Wang, B., Wu, N., & Lan, C. Q. (2008) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-008-1681-1 · Cited by 1,116 · see citing works

Handbook of Microalgal Culture. Biotechnology and Applied Phycology

Moi, P. S. (2004) · Journal of Applied Phycology · doi:10.1023/b:japh.0000044943.45511.5e · Cited by 920 · see citing works

Handbook of Microalgal Culture: Biotechnology and Applied Phycology

(2003) · doi:10.1002/9780470995280 · Cited by 886 · see citing works

Photorespiration: players, partners and origin

Bauwe, H., Hagemann, M., & Fernie, A. R. (2010) · Trends in Plant Science · doi:10.1016/j.tplants.2010.03.006 · Cited by 652 · see citing works

The impact of nitrogen starvation on the dynamics of triacylglycerol accumulation in nine microalgae strains

Breuer, G., Lamers, P. P., Martens, D. E., Draaisma, R. B., & Wijffels, R. H. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.08.003 · Cited by 626 · see citing works

Advances and perspectives in using microalgae to produce biodiesel

Amaro, H. M., Guedes, A. C., & Malcata, F. X. (2011) · Applied Energy · doi:10.1016/j.apenergy.2010.12.014 · Cited by 572 · see citing works

Draft genome sequence and genetic transformation of the oleaginous alga Nannochloropsis gaditana

Radakovits, R., Jinkerson, R. E., Fuerstenberg, S. I., Tae, H., Settlage, R. E., Boore, J. L., & Posewitz, M. C. (2012) · Nature Communications · doi:10.1038/ncomms1688 · Cited by 520 · see citing works

Effects of Growth Irradiance and Nitrogen Limitation on Photosynthetic Energy Conversion in Photosystem II

Kolber, Z., Zehr, J. P., & Falkowski, P. G. (1988) · PLANT PHYSIOLOGY · doi:10.1104/pp.88.3.923 · Cited by 493 · see citing works

Enhanced lipid production of Chlorella vulgaris by adjustment of cultivation conditions

Lv, J.-M., Cheng, L., Xu, X., Zhang, L., & Chen, H. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.03.120 · Cited by 464 · see citing works

Genome, Functional Gene Annotation, and Nuclear Transformation of the Heterokont Oleaginous Alga Nannochloropsis oceanica CCMP1779

Vieler, A., Wu, G., Tsai, C.-H., Bullard, B., Cornish, A. J., Harvey, C., Reca, I.-B., Thornburg, C., Achawanantakun, R., Buehl, C. J., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1003064 · Cited by 458 · see citing works

Engineering algae for biohydrogen and biofuel production

Beer, L. L., Boyd, E. S., Peters, J. W., & Posewitz, M. C. (2009) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2009.06.002 · Cited by 449 · see citing works

Microalgae: The Potential for Carbon Capture

Sayre, R. T. (2010) · BioScience · doi:10.1525/bio.2010.60.9.9 · Cited by 414 · see citing works

Choreography of Transcriptomes and Lipidomes of <i>Nannochloropsis</i> Reveals the Mechanisms of Oil Synthesis in Microalgae

Li, J., Han, D., Wang, D., Ning, K., Jia, J., Wei, L., Jing, X., Huang, S., Chen, J., Li, Y., et al. (2014) · The Plant Cell · doi:10.1105/tpc.113.121418 · Cited by 412 · see citing works

Metabolic and gene expression changes triggered by nitrogen deprivation in the photoautotrophically grown microalgae Chlamydomonas reinhardtii and Coccomyxa sp. C-169

Msanne, J., Xu, D., Konda, A. R., Casas-Mollano, J. A., Awada, T. N., Cahoon, E. B., & Cerutti, H. D. (2012) · Phytochemistry · doi:10.1016/j.phytochem.2011.12.007 · Cited by 389 · see citing works

The use of fluorescent Nile red and BODIPY for lipid measurement in microalgae

Rumin, J., Bonnefond, H., Saint-Jean, B., Rouxel, C., Sciandra, A., Bernard, O., Cadoret, J.-P., & Bougaran, G. (2015) · Biotechnology for Biofuels · doi:10.1186/s13068-015-0220-4 · Cited by 386 · see citing works

Sustainable biofuels from algae

Borowitzka, M. A., & Moheimani, N. R. (2013) · Mitigation and Adaptation Strategies for Global Change · doi:10.1007/s11027-010-9271-9 · Cited by 374 · see citing works

The response of diatom central carbon metabolism to nitrogen starvation is different from that of green algae and higher plants

Hockin, N. L., Mock, T., Mulholland, F., Kopriva, S., & Malin, G. (2012) · PLANT PHYSIOLOGY · doi:10.1104/pp.111.184333 · Cited by 372 · see citing works

Molecular and cellular mechanisms of neutral lipid accumulation in diatom following nitrogen deprivation

Yang, Z.-K., Niu, Y., Ma, Y.-H., Xue, J., Zhang, M.-H., Yang, W.-D., Liu, J.-S., Lu, S.-H., Guan, Y., & Li, H. (2013) · Biotechnology for Biofuels · doi:10.1186/1754-6834-6-67 · Cited by 366 · see citing works

The Response of Nannochloropsis gaditana to Nitrogen Starvation Includes De Novo Biosynthesis of Triacylglycerols, a Decrease of Chloroplast Galactolipids, and Reorganization of the Photosynthetic Apparatus

Simionato, D., Block, M. A., Rocca, N. L., Jouhet, J., Maréchal, É., Finazzi, G., & Morosinotto, T. (2013) · Eukaryotic Cell · doi:10.1128/ec.00363-12 · Cited by 366 · see citing works

Systematic investigation of biomass and lipid productivity by microalgae in photobioreactors for biodiesel application

Pruvost, J., Vooren, G. V., Gouic, B. L., Couzinet‐Mossion, A., & Legrand, J. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.06.153 · Cited by 331 · see citing works

Microalgae bioengineering: From CO2 fixation to biofuel production

Zeng, X., Danquah, M. K., Chen, X. D., & Lu, Y. (2011) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2011.04.014 · Cited by 299 · see citing works

Photosynthetic carbon partitioning and lipid production in the oleaginous microalga Pseudochlorococcum sp. (Chlorophyceae) under nitrogen-limited conditions

Li, Y., Han, D., Sommerfeld, M. R., & Hu, Q. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.06.036 · Cited by 294 · see citing works

Nannochloropsis Genomes Reveal Evolution of Microalgal Oleaginous Traits

Wang, D., Ning, K., Li, J., Hu, J., Han, D., Wang, H., Zeng, X., Jing, X., Zhou, Q., Su, X., et al. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004094 · Cited by 268 · see citing works

Manipulation of microalgal lipid production using genetic engineering

Dünahay, T. G., Jarvis, E. E., Dais, S. S., & Roessler, P. G. (1996) · Applied Biochemistry and Biotechnology · doi:10.1007/bf02941703 · Cited by 268 · see citing works

Differential Effects of Nitrogen Limitation on Photosynthetic Efficiency of Photosystems I and II in Microalgae

Berges, J. A., Charlebois, D., Mauzerall, D. C., & Falkowski, P. G. (1996) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.2.689 · Cited by 261 · see citing works

Oil accumulation is controlled by carbon precursor supply for fatty acid synthesis in Chlamydomonas reinhardtii

Fan, J., Yan, C., Andre, C., Shanklin, J., Schwender, J., & Xu, C. (2012) · Plant and Cell Physiology · doi:10.1093/pcp/pcs082 · Cited by 248 · see citing works

Manipulation of Microalgal Lipid Production Using Genetic Engineering

Dünahay, T. G., Jarvis, E. E., Dais, S. S., & Roessler, P. G. (1996) · Humana Press eBooks · doi:10.1007/978-1-4612-0223-3_20 · Cited by 246 · see citing works

Molecular mechanisms for photosynthetic carbon partitioning into storage neutral lipids in Nannochloropsis oceanica under nitrogen-depletion conditions

Jia, J., Han, D., Gerken, H. G., Li, Y., Sommerfeld, M. R., Hu, Q., & Xu, J. (2014) · Algal Research · doi:10.1016/j.algal.2014.11.005 · Cited by 239 · see citing works

Examination of Triacylglycerol Biosynthetic Pathways via De Novo Transcriptomic and Proteomic Analyses in an Unsequenced Microalga

Guarnieri, M. T., Nag, A., Smolinski, S. L., Darzins, A., Seibert, M., & Pienkos, P. T. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025851 · Cited by 234 · see citing works

Determination of nitrate plus nitrite in small volume marine water samples using vanadium(III)chloride as a reduction agent

Schnetger, B., & Lehners, C. (2014) · Marine Chemistry · doi:10.1016/j.marchem.2014.01.010 · Cited by 226 · see citing works

Characterization and optimization of carbohydrate production from an indigenous microalga Chlorella Vulgaris FSP-E

Ho, S.-H., Huang, S.-W., Chen, C.-Y., Hasunuma, T., Kondo, A., & Chang, J.-S. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2012.10.100 · Cited by 216 · see citing works

Chromosome Scale Genome Assembly and Transcriptome Profiling of Nannochloropsis gaditana in Nitrogen Depletion

Carpinelli, E. C., Telatin, A., Vitulo, N., Forcato, C., D’Angelo, M., Schiavon, R., Vezzi, A., Giacometti, G. M., Morosinotto, T., & Valle, G. (2013) · Molecular Plant · doi:10.1093/mp/sst120 · Cited by 213 · see citing works

Potential role of multiple carbon fixation pathways during lipid accumulation in Phaeodactylum tricornutum

Valenzuela, J. J., Mazurie, A., Carlson, R. P., Gerlach, R., Cooksey, K. E., Peyton, B., & Fields, M. W. (2012) · Biotechnology for Biofuels · doi:10.1186/1754-6834-5-40 · Cited by 204 · see citing works

Responses of the photosynthetic apparatus of Dunaliella tertiolecta (Chlorophyceae) to nitrogen and phosphorus limitation

Geider, R. J., MacIntyre, H. L., Graziano, L. M., & McKay, R. M. L. (1998) · European Journal of Phycology · doi:10.1080/09670269810001736813 · Cited by 176 · see citing works

Responses of<i>Nannochloropsis oceanica</i>IMET1 to Long-Term Nitrogen Starvation and Recovery

Dong, H.-P., Williams, E., Wang, D.-Z., Xie, Z.-X., Hsia, R.-C., Jenck, A., Halden, R., Li, J., Chen, F., & Place, A. R. (2013) · Plant Physiology · doi:10.1104/pp.113.214320 · Cited by 173 · see citing works

Gene Regulation of Carbon Fixation, Storage, and Utilization in the DiatomPhaeodactylum tricornutumAcclimated to Light/Dark Cycles

Chauton, M. S., Winge, P., Brembu, T., Vadstein, Ô., & Bones, A. M. (2012) · PLANT PHYSIOLOGY · doi:10.1104/pp.112.206177 · Cited by 164 · see citing works

Impact of nitrogen limitation on biomass, photosynthesis, and lipid accumulation in Chlorella sorokiniana

Negi, S., Barry, A. N., Friedland, N., Sudasinghe, N., Subramanian, S., Pieris, S., Holguin, F. O., Dungan, B., Schaub, T., & Sayre, R. (2016) · Journal of Applied Phycology · doi:10.1007/s10811-015-0652-z · Cited by 156 · see citing works

Effects of nitrogen supplementation of the culture medium on the growth, total lipid content and fatty acid profiles of three microalgae (Tetraselmis subcordiformis, Nannochloropsis oculata and Pavlova viridis)

Huang, X., Huang, Z., Wen, W., & Yan, J. (2012) · Journal of Applied Phycology · doi:10.1007/s10811-012-9846-9 · Cited by 150 · see citing works

Integrated Quantitative Analysis of Nitrogen Stress Response inChlamydomonas reinhardtiiUsing Metabolite and Protein Profiling

Wase, N. V., Black, P. N., Stanley, B. A., & Dirusso, C. (2014) · Journal of Proteome Research · doi:10.1021/pr400952z · Cited by 148 · see citing works

Investigation of fatty acids accumulation in Nannochloropsis oculata for biodiesel application

Vooren, G. V., Grand, F. L., Legrand, J., Cuiné, S., Peltier, G., & Pruvost, J. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.08.009 · Cited by 142 · see citing works

The metabolic blueprint of Phaeodactylum tricornutum reveals a eukaryotic Entner–Doudoroff glycolytic pathway

Fabris, M., Matthijs, M., Rombauts, S., Vyverman, W., Goossens, A., & Baart, G. J. E. (2012) · The Plant Journal · doi:10.1111/j.1365-313x.2012.04941.x · Cited by 138 · see citing works

Nutrient deprivation enhances lipid content in marine microalgae

Gao, Y., Yang, M., & Wang, C. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2013.08.066 · Cited by 131 · see citing works

A Lipid Droplet Protein of Nannochloropsis with Functions Partially Analogous to Plant Oleosins

Vieler, A., Brubaker, S. B., Vick, B., & Christoph Benning, A. (2012) · PLANT PHYSIOLOGY · doi:10.1104/pp.111.193029 · Cited by 126 · see citing works

Factors in mass cultivation of microalgae for biodiesel

Zhu, J., Rong, J., & Zong, B. (2013) · CHINESE JOURNAL OF CATALYSIS (CHINESE VERSION) · doi:10.1016/s1872-2067(11)60497-x · Cited by 120 · see citing works

Omics in algae: Paving the way for a systems biological understanding of algal stress phenomena?

Jamers, A., Blust, R., & Coen, W. D. (2009) · Aquatic Toxicology · doi:10.1016/j.aquatox.2009.02.012 · Cited by 120 · see citing works

Genetic Engineering Approaches for Enhanced Production of Biodiesel Fuel from Microalgae

Roessler, P. G., Brown, L. M., Dünahay, T. G., Heacox, D. A., Jarvis, E., Schneider, J. C., Talbot, S., & Zeiler, K. G. (1994) · ACS symposium series · doi:10.1021/bk-1994-0566.ch013 · Cited by 106 · see citing works

Metabolic profiles of Nannochloropsis oceanica IMET1 under nitrogen-deficiency stress

Xiao, Y., Zhang, J., Cui, J., Feng, Y., & Cui, Q. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2012.11.116 · Cited by 101 · see citing works

Genomic insights from the oleaginous model alga Nannochloropsis gaditana

Jinkerson, R. E., Radakovits, R., & Posewitz, M. C. (2012) · Bioengineered · doi:10.4161/bioe.21880 · Cited by 97 · see citing works

Effects of nitrogen concentration and media replacement on cell growth and lipid production of oleaginous marine microalga Nannochloropsis oceanica DUT01

Wan, C., Bai, F., & Zhao, X. (2013) · Biochemical Engineering Journal · doi:10.1016/j.bej.2013.04.014 · Cited by 88 · see citing works

Lipidomic profiling and discovery of lipid biomarkers in snow alga Chlamydomonas nivalis under salt stress

Lu, N., Wei, D., Chen, F., & Yang, S. (2011) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201100248 · Cited by 81 · see citing works

Knockdown of phosphoenolpyruvate carboxykinase increases carbon flux to lipid synthesis in Phaeodactylum tricornutum

Yang, J., Pan, Y., Bowler, C., Zhang, L., & Hu, H. (2016) · Algal Research · doi:10.1016/j.algal.2016.02.004 · Cited by 80 · see citing works

Comparison of two-dimensional electrophoresis patterns of heat shock protein Hsp27 species in normal and cardiomyopathic hearts

Scheler, C., Li, X., Salnikow, J., Dunn, M. J., & Jungblut, P. R. (1999) · Electrophoresis · doi:10.1002/(sici)1522-2683(19991201)20:18 · Cited by 72 · see citing works

Variations in Lipid and Fatty Acid Content in Relation to Acetyl CoA Carboxylase in the Marine Prymnesiophyte Isochrysis galbana

Sukenik, A., & Livne, A. (1991) · Plant and Cell Physiology · doi:10.1093/oxfordjournals.pcp.a078090 · Cited by 70 · see citing works

Comparative proteomics reveals proteins impacted by nitrogen deprivation in wild-type and high lipid-accumulating mutant strains of Tisochrysis lutea

Garnier, M., Carrier, G., Rogniaux, H., Nicolau, É., Bougaran, G., Saint‐Jean, B., & Cadoret, J. (2014) · Journal of Proteomics · doi:10.1016/j.jprot.2014.02.022 · Cited by 70 · see citing works

The use of Trizol reagent (phenol/guanidine isothiocyanate) for producing high quality two-dimensional gel electrophoretograms (2-DE) of dinoflagellates

Lee, F. W. F., & Lo, S. C. (2008) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2008.01.006 · Cited by 67 · see citing works

Proteomic Analysis of Cadmium-Induced Protein Profile Alterations from Marine Alga Nannochloropsis oculata

KIM, Y. K., Yoo, W., Lee, S. H., & LEE, M. Y. (2005) · Ecotoxicology · doi:10.1007/s10646-005-0009-5 · Cited by 65 · see citing works

Simultaneous estimation of chlorophyll a and lipid contents in microalgae by three‐color analysis

Su, C., Fu, C., Chang, Y., Giridhar, R., Ye, J., Chu, I., & Wu, W. (2007) · Biotechnology and Bioengineering · doi:10.1002/bit.21623 · Cited by 59 · see citing works

A pangenomic analysis of the Nannochloropsis organellar genomes reveals novel genetic variations in key metabolic genes

Starkenburg, S. R., Kwon, K. J., Jha, R. K., McKay, C., Jacobs, M., Chertkov, O., Twary, S. N., Rocap, G., & Cattolico, R. A. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-212 · Cited by 57 · see citing works

Improving the reliability of fluorescence-based neutral lipid content measurements in microalgal cultures

De la Hoz Siegler, H., Ayidzoe, W., Ben-Zvi, A., Burrell, R. E., & McCaffrey, W. C. (2012) · Algal Research · doi:10.1016/j.algal.2012.07.004 · Cited by 57 · see citing works

Ubiquitin family proteins and their relationship to the proteasome: a structural perspective.

Walters, K., Goh, A. M., Wang, Q.-H., Wagner, G., & Howley, P. (2004) · Biochimica et Biophysica Acta · doi:10.1016/j.bbamcr.2004.10.005 · Cited by 55 · see citing works

The Effect of Diel Temperature and Light Cycles on the Growth of Nannochloropsis oculata in a Photobioreactor Matrix

Tamburic, B., Guruprasad, S., Radford, D. T., Szabó, M., Lilley, R. M., Larkum, A. W. D., Franklin, J. B., Kramer, D., Blackburn, S. I., Raven, J. A., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086047 · Cited by 53 · see citing works

Transcriptome sequencing, annotation and expression analysis of Nannochloropsis sp. at different growth phases

Zheng, M., Tian, J., Yang, G., Zheng, L., Chen, G., Chen, J., & Wang, B. (2013) · Gene · doi:10.1016/j.gene.2013.04.005 · Cited by 41 · see citing works

Molecular ecological responses of dinoflagellate, Karenia mikimotoi to environmental nitrate stress

Lei, Q.-Y., & Lü, S. (2011) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.09.021 · Cited by 31 · see citing works

Gas Transfer Controls Carbon Limitation During Biomass Production by Marine Microalgae

Tamburic, B., Evenhuis, C. R., Suggett, D. J., Larkum, A. W. D., Raven, J. A., & Ralph, P. J. (2015) · ChemSusChem · doi:10.1002/cssc.201500332 · Cited by 21 · see citing works

Bioengineering of Microalgae: Recent Advances, Perspectives, and Regulatory Challenges for Industrial Application

Kumar, G., Shekh, A., Jakhu, S., Sharma, Y., Kapoor, R., & Sharma, T. R. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00914 · Cited by 315 · see citing works

Microalgae Chlorella vulgaris biomass harvesting by natural flocculant: effects on biomass sedimentation, spent medium recycling and lipid extraction

Zhu, L., Li, Z., & Hiltunen, E. (2018) · Biotechnology for Biofuels · doi:10.1186/s13068-018-1183-z · Cited by 215 · see citing works

Microalgae biofuels: illuminating the path to a sustainable future amidst challenges and opportunities

Wang, M., Ye, X., Bi, H., & Shen, Z. (2024) · Biotechnology for Biofuels and Bioproducts · doi:10.1186/s13068-024-02461-0 · Cited by 201 · see citing works

Isolation of Industrial Important Bioactive Compounds from Microalgae

Balasubramaniam, V. R. M. T., Rathi, D.-N. G., Mustar, S., Lee, J. C., & Noh, M. F. M. (2021) · Molecules · doi:10.3390/molecules26040943 · Cited by 159 · see citing works

Omics approaches for microalgal applications: Prospects and challenges

Mishra, A., Medhi, K., Malaviya, P., & Thakur, I. S. (2019) · Bioresource Technology · doi:10.1016/j.biortech.2019.121890 · Cited by 141 · see citing works

Leveraging algal omics to reveal potential targets for augmenting TAG accumulation

Arora, N., Pienkos, P. T., Pruthi, V., Poluri, K. M., & Guarnieri, M. T. (2018) · Biotechnology Advances · doi:10.1016/j.biotechadv.2018.04.005 · Cited by 98 · see citing works

Insights into the genetic and metabolic engineering approaches to enhance the competence of microalgae as biofuel resource: A review

Brar, A., Kumar, M., Soni, T., Vivekanand, V., & Pareek, N. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.125597 · Cited by 96 · see citing works

Algal Biomass Utilization toward Circular Economy

Zabochnicka-Świątek, M., Krzywonos, M., Romanowska‐Duda, Z., Szufa, S., Darkalt, A., & Mubashar, M. (2022) · Life · doi:10.3390/life12101480 · Cited by 79 · see citing works

Recent advances in biotechnology and bioengineering for efficient microalgal biofuel production

Zhang, C., Singh, R. P., Yadav, P., Kumar, I., Kaushik, A., Roychowdhury, R., Mubeen, M., Singh, S. K., Kumar, A., & Wang, J. (2025) · Fuel Processing Technology · doi:10.1016/j.fuproc.2025.108199 · Cited by 71 · see citing works

Photoprotection mechanisms of Nannochloropsis oceanica in response to light stress

Wang, B., & Jia, J. (2020) · Algal Research · doi:10.1016/j.algal.2019.101784 · Cited by 64 · see citing works

Can Omics Approaches Improve Microalgal Biofuels under Abiotic Stress?

Salama, E., Govindwar, S. P., Khandare, R. V., Roh, H., Jeon, B., & Li, X. (2019) · Trends in Plant Science · doi:10.1016/j.tplants.2019.04.001 · Cited by 62 · see citing works

Transcriptomic survey on the microcystins production and growth of Microcystis aeruginosa under nitrogen starvation

Zhou, Y., Li, X., Xia, Q., & Dai, R. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.134501 · Cited by 54 · see citing works

Microalgae stress sensing through oxidative phosphorylation drives bioenergy potential: Deciphering mechanisms and future opportunities

Ugya, A. Y., Li, X., Chen, H., & Wang, Q. (2024) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2024.114266 · Cited by 48 · see citing works

Integration of proteome and transcriptome refines key molecular processes underlying oil production in Nannochloropsis oceanica

You, W., Wei, L., Gong, Y., Hajjami, M. E., Xu, J., & Poetsch, A. (2020) · Biotechnology for Biofuels · doi:10.1186/s13068-020-01748-2 · Cited by 45 · see citing works

Use of magnetic fields and nitrate concentration to optimize the growth and lipid yield of Nannochloropsis oculata

Chu, F.-J., Wan, T., Pai, T., Lin, H., Liu, S., & Huang, C.-F. (2019) · Journal of Environmental Management · doi:10.1016/j.jenvman.2019.109680 · Cited by 37 · see citing works

Algal Biofuels: An Economic and Effective Alternative of Fossil Fuels

Bhardwaj, N., Agrawal, K., & Verma, P. (2020) · Clean Energy Production Technologies · doi:10.1007/978-981-15-7190-9_7 · Cited by 36 · see citing works

Evaluation of changes in Microcystis aeruginosa growth and microcystin production by urea via transcriptomic surveys

Zhou, Y., Zhang, X., Li, X., Jia, P., & Dai, R. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.11.100 · Cited by 30 · see citing works

Winery waste valorisation as microalgae culture medium: A step forward for food circular economy

Spennati, E., Casazza, A. A., Converti, A., Padula, M. P., Dehghani, F., Perego, P., & Valtchev, P. (2022) · Separation and Purification Technology · doi:10.1016/j.seppur.2022.121088 · Cited by 28 · see citing works

Multiomics and optobiotechnological approaches for the development of microalgal strain for production of aviation biofuel and biorefinery

Kumar, A., Baldia, A., Rajput, D., Kateriya, S., Babu, V., & Dubey, K. K. (2022) · Bioresource Technology · doi:10.1016/j.biortech.2022.128457 · Cited by 28 · see citing works

An empirical process model to predict microalgal carbon fixation rates in photobioreactors

Tamburic, B., Evenhuis, C. R., Crosswell, J. R., & Ralph, P. J. (2018) · Algal Research · doi:10.1016/j.algal.2018.02.014 · Cited by 24 · see citing works

Life-cycle assessment of flue gas CO2 fixation from coal-fired power plant and coal chemical plant by microalgae

Ye, Q., Shen, Y., Zhang, Q., Wu, X., & Guo, W. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.157728 · Cited by 23 · see citing works

Development of New Antiproliferative Compound against Human Tumor Cells from the Marine Microalgae Nannochloropsis gaditana by Applied Proteomics

Carrasco-Reinado, R., Escobar-Niño, A., Fajardo, C., Bermejo, I. M. M., Amil‐Ruíz, F., Martı́nez-Rodrı́guez, G., Fuentes-Almagro, C. A., Capilla, V., Tomás‐Cobos, L., Soriano-Romaní, L., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010096 · Cited by 21 · see citing works

Comparative Proteomics Reveals Evidence of Enhanced EPA Trafficking in a Mutant Strain of Nannochloropsis oculata

Razali, W. A. W., Evans, C. A., & Pandhal, J. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.838445 · Cited by 20 · see citing works

Transcriptome analysis of lipid metabolism in response to cerium stress in the oleaginous microalga Nannochloropsis oculata

Wu, D., Hou, Y., Cheng, J., Han, T., Hao, N., Zhang, B., Fan, X., Ji, X., Chen, F., Gong, D., et al. (2022) · Science of The Total Environment · doi:10.1016/j.scitotenv.2022.156420 · Cited by 20 · see citing works

Outdoor pilot-scale cultivation and techno economic assessment of a novel omega-3 eicosapentaenoic acid over-producing Nannochloropsis oculata strain

Razali, W. A. W., & Pandhal, J. (2023) · Bioresource Technology Reports · doi:10.1016/j.biteb.2023.101682 · Cited by 20 · see citing works

Insight into the mechanism of nitrogen sufficiency conversion strategy for microalgae-based ammonium-rich wastewater treatment

Song, H., Li, J., Su, Q., Li, H., Guo, X., Shao, S., Fan, L., Xu, P., Zhou, W., & Qian, J. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.140904 · Cited by 20 · see citing works

Microalgal Biomass of Industrial Interest: Methods of Characterization

Dupré, C., Burrows, H. D., Campos, M. G., Delattre, C., Encarnação, T., Fauchon, M., Gaignard, C., Hellio, C., Ito, J., Laroche, C., et al. (2020) · Springer eBooks · doi:10.1007/978-3-030-35020-8_4 · Cited by 16 · see citing works

Effect of biphasic temperature regime on therapeutic recombinant protein production in the green alga Chlamydomonas reinhardtii

Commault, A. S., Walia, N. K., Fabris, M., Barolo, L., Siboni, N., Adriaans, J., Ralph, P. J., & Pernice, M. (2020) · Algal Research · doi:10.1016/j.algal.2020.101997 · Cited by 14 · see citing works

Reconstruction of Long-Chain Polyunsaturated Acid Synthesis Pathways in Marine Red Microalga Porphyridium cruentum Using Lipidomics and Transcriptomics

Li, T., Li, C., Wang, W., Wu, H., Wu, H., Xu, J. H., & Xiang, W. (2024) · Marine Drugs · doi:10.3390/md22020082 · Cited by 10 · see citing works

Hydrothermal liquefaction of swine wastewater-cultivated Chlorella sorokiniana SU-1 biomass for sustainable biofuel production

Kusmayadi, A., Ong, H. C., Amir, F., Riayatsyah, T. M. I., Leong, Y. K., & Chang, J. (2024) · Biochemical Engineering Journal · doi:10.1016/j.bej.2024.109383 · Cited by 10 · see citing works

Advanced Gene Technology and Synthetic Biology Approaches to Custom Design Microalgae for Biodiesel Production

Arora, N., Tripathi, S., Poluri, K. M., & Pruthi, V. (2019) · Springer eBooks · doi:10.1007/978-981-13-2264-8_8 · Cited by 9 · see citing works

In situ monitoring of chlorophyll <i>a</i> fluorescence in <i>Nannochloropsis oceanica</i> cultures to assess photochemical changes and the onset of lipid accumulation during nitrogen deprivation

Carneiro, M., Chini Zittelli, G., Cicchi, B., Touloupakis, E., Faraloni, C., Maia, I. B., Pereira, H., Santos, T., Malcata, F. X., Otero, A., et al. (2021) · Biotechnology and Bioengineering · doi:10.1002/bit.27906 · Cited by 10 · see citing works

From Upstream Assessment to Downstream Energy Conversion: A Systematic Review of Advances in Biomass Residue Utilization Techniques

Kabir, M., Cortés, I. L., Gisbert, C. M. F., Moposita-Vasquez, D.-D., & Velázquez-Martí, B. (2026) · Biomass · doi:10.3390/biomass6020024 · Cited by 8 · see citing works

Variation in the fatty acid composition of microalgal lipids due to the effect of the extraction method

Pérez-Barradas, F. V., Ortega‐Clemente, L. A., Pérez‐Legaspi, I. A., Jiménez‐García, M. I., Huerta‐Heredia, A. A., & Quintana‐Castro, R. (2023) · Journal of Applied Phycology · doi:10.1007/s10811-023-03092-y · Cited by 8 · see citing works

Omics Approaches for Algal Applications

Faisal, S., Dixit, D., Elsayed, M., & Behera, D. P. (2023) · Springer eBooks · doi:10.1007/978-3-031-42026-9_12 · Cited by 7 · see citing works

Next Generation Biofuel Production in the Omics Era: Potential and Prospects

Kumar, S., Singh, N. K., Kumar, A., & Shukla, P. (2021) · Springer eBooks · doi:10.1007/978-981-16-2956-3_11 · Cited by 7 · see citing works

Effect of Heterologous Expression of Key Enzymes Involved in Astaxanthin and Lipid Synthesis on Lipid and Carotenoid Production in Aurantiochytrium sp.

Shao, Y., Gao, Z., Sun, F., Cui, Y., Zou, X., Ma, J., Wang, Q., Zhang, H., Wu, Y., & Meng, C. (2025) · Marine Drugs · doi:10.3390/md23040164 · Cited by 6 · see citing works

Strain Improvement Through Genetic Engineering and Synthetic Biology for the Creation of Microalgae with Enhanced Lipid Accumulation, Stress Tolerance, and Production of High-value

Molla, A., & Abebe, G. M. (2025) · Science Frontiers · doi:10.11648/j.sf.20250603.14 · Cited by 5 · see citing works

The pivotal role of omics technologies in the production of third and fourth generation biodiesel

Ijoma, G. N., Mannie, T., Lokwe, G. N., Ogola, H. J. O., Kalu, C. M., & Tekere, M. (2025) · Biofuels · doi:10.1080/17597269.2025.2564504 · Cited by 5 · see citing works

Effect of the deficiency of nitrate and silicate on the growth and composition of the benthic diatom Navicula incerta

Encinas-Arzate, J. D. J., Márquez‐Ríos, E., López‐Elías, J. A., Torres‐Arreola, W., Huerta‐Ocampo, J. Á., & Ramírez‐Suárez, J. C. (2020) · Latin American Journal of Aquatic Research · doi:10.3856/vol48-issue2-fulltext-2314 · Cited by 5 · see citing works

A Mathematical Model of Neutral Lipid Content in terms of Initial Nitrogen Concentration and Validation in Coelastrum sp. HA-1 and Application in Chlorella sorokiniana

Yang, Z., Zhao, Y., Liu, Z., Liu, C., Hu, Z., & Hou, Y. (2017) · BioMed Research International · doi:10.1155/2017/9253020 · Cited by 5 · see citing works

Enhancing lipid accumulation in marine microalgae for sustainable biofuel applications: A review of Nannochloropsis and Tetraselmis

Doan, L., Tran, A. Q. V., Ong, Q. K. L., Huynh, K. G., Tran, K., & Phung, T. K. (2026) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2026.109210 · Cited by 4 · see citing works

Targeted microalgal bioenergy production from the perspective of photosynthetic electron transport chain

Liu, Y., Zheng, M., Wang, W., Chen, Z., Zhang, X., Wu, B., Hu, Z., & Han, H. (2026) · Biotechnology Advances · doi:10.1016/j.biotechadv.2026.108875 · Cited by 3 · see citing works

Nitrogen excess induces cytokinesis arrest and alters lipid metabolism in the bloom-forming desmid Cosmarium tinctum

Kang, S., Kim, K.-H., Shin, H. H., Kim, J.-H., Kim, B.-H., & Li, Z. (2025) · Water Research X · doi:10.1016/j.wroa.2025.100394 · Cited by 2 · see citing works

Global Status of Microbial Engineering for Biofuel Production - Advances, Challenges, and Roadmap

Semalty, S., Bhardwaj, A., & Karn, S. K. (2024) · Environmental science and engineering · doi:10.1007/978-3-031-52167-6_24 · Cited by 2 · see citing works

Biphasic optimization approach for maximization of lipid production by the microalga Chlorella pyrenoidosa

Sukačová, K., Búzová, D., & Červený, J. (2020) · Folia Microbiologica · doi:10.1007/s12223-020-00800-w · Cited by 2 · see citing works

Polyploid Induction Enhance Pigment Production in Nannochoropsis oculata: A study using a mutagenesis agent.Preprint

Rahmawati, K., Yunianta, Y., & Risjani, Y. (2023) · Research Square · doi:10.21203/rs.3.rs-2493793/v1 · Cited by 1 · see citing works

The Use of Omics Technologies, Random Mutagenesis, and Genetic Transformation Techniques to Improve Algae for Biodiesel Industry

Adıgüzel, A. O. (2022) · Clean Energy Production Technologies · doi:10.1007/978-981-19-6806-8_2

Mass spectrometry

Naira, V. R., Kareya, M. S., Nesamma, A. A., & Jutur, P. P. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91684-4.00012-8

Protease secreting Nannochloropsis limnetica can valorise invasive plants through circular water-use and accumulate neutral lipidsPreprint

Iyer, A. B., Heneghan, P. G., Dillion, E. T., & Halim, R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.11.29.691304

A state-of-the-art in exploring microalgal vitamins: Advancements in production, extraction, market potential, applications, and perspectives for a sustainable future

Maity, S., & Yadav, A. K. (2026) · Preparative Biochemistry & Biotechnology · doi:10.1080/10826068.2026.2625200

Enhancing the Recovery of Antioxidant Compounds from Microalgae-Cyanobacteria Consortia Through Alcalase Hydrolysis: A Focus on Bioactive Peptides

de Donlebún, B. P., del Álamo, R., Águila-Carricondo, P., de la Roche, J. P., Gómez‐Cortés, P., & Hernández‐Ledesma, B. (2026) · Marine Drugs · doi:10.3390/md24050184

Enhancing desalination and biomass accumulation of Nannochloropsis sp. in brackish water reverse osmosis concentrate using indole-3-acetic acid and gibberellic acid

Xu, H., Guo, M., Yue, B., Chen, F., Li, X., Hu, T., & Yang, Y. (2026) · Algal Research · doi:10.1016/j.algal.2026.104982

Proteomics to reveal metabolic network shifts towards lipid accumulation following nitrogen deprivation in the diatom Phaeodactylum tricornutum

Yang, Z.-K., Ma, Y., Zheng, J.-W., Yang, W., Liu, J., & Li, H. (2013) · Journal of Applied Phycology · doi:10.1007/s10811-013-0050-3 · Cited by 129 · see citing works

Proteomic and Transcriptomic Patterns during Lipid Remodeling in Nannochloropsis gaditana

Hulatt, C. J., Smolina, I., Dowle, A., Kopp, M., Vasanth, G. K., Hoarau, G. G., Wijffels, R. H., & Kiron, V. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186946 · Cited by 38 · see citing works

Real-time iTRAQ-based proteome profiling revealed the central metabolism involved in nitrogen starvation induced lipid accumulation in microalgae

Rai, V., Muthuraj, M., Gandhi, M., Das, D., & Srivastava, S. (2017) · Scientific Reports · doi:10.1038/srep45732 · Cited by 82 · see citing works

Proteome response of Phaeodactylum tricornutum, during lipid accumulation induced by nitrogen depletion

Longworth, J., Wu, D., Huete‐Ortega, M., Wright, P. C., & Vaidyanathan, S. (2016) · Newcastle University ePrints (Newcastle Univesity) · doi:10.25405/ncl.34287216

A nitrogen-deprivation-activated gene promotes oil production in an oleaginous microalga Nannochloropsis oceanica

Gan, Q., Wang, X., Liang, S., Lei, S., Lu, X., Xin, Y., & Lu, Y. (2026) · Industrial Crops and Products · doi:10.1016/j.indcrop.2025.122553 · Cited by 2 · see citing works