Effects of nitrogen sources on cell growth and lipid accumulation of green alga Neochloris oleoabundans
Abstract
Microalgal lipids are the oils of future for sustainable biodiesel production. However, relatively high production costs due to low lipid productivity have been one of the major obstacles impeding their commercial production. We studied the effects of nitrogen sources and their concentrations on cell growth and lipid accumulation of Neochloris oleoabundans, one of the most promising oil-rich microalgal species. While the highest lipid cell content of 0.40 g/g was obtained at the lowest sodium nitrate concentration (3 mM), a remarkable lipid productivity of 0.133 g l(-1) day(-1) was achieved at 5 mM with a lipid cell content of 0.34 g/g and a biomass productivity of 0.40 g l(-1) day(-1). The highest biomass productivity was obtained at 10 mM sodium nitrate, with a biomass concentration of 3.2 g/l and a biomass productivity of 0.63 g l(-1) day(-1). It was observed that cell growth continued after the exhaustion of external nitrogen pool, hypothetically supported by the consumption of intracellular nitrogen pools such as chlorophyll molecules. The relationship among nitrate depletion, cell growth, lipid cell content, and cell chlorophyll content are discussed.
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Klanchui et al. analyzed depletion of NO3−, PO4−, and SO4− to obtain glycogen-enriched biomass of A. platensis; reduction in SO4− increased yield of glycogen production 300% compared to control after 24 h, but after 96 h amounts of glycogen were similar to NO3− depletion (60% DW).
“Klanchui et al. [60] analyzed the effect of depletion of NO 3-, PO4 3-, and SO4 2-to obtain a glycogen-enriched biomass of Arthrospira platensis, where it seems that the reduction in SO4 2-increased the yield of glycogen production 300% compared to the control after just 24 h of incubation, nevertheless, after 96 h of incubation, the amounts of glycogen obtained were similar to NO 3-depletion (60%”
From Arthrospira platensis as a Feasible Feedstock for Bioethanol Production (2021) · cites this paper as [60]
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- Authors
- Li, Y., Horsman, M., Wang, B., Wu, N., & Lan, C. Q.
- Affiliations
- University of Ottawa (CA)
- Corresponding author
- Lan, Christopher Q.
- Venue
- Applied Microbiology and Biotechnology
- Published
- 2008-12
- Volume
- 81
- Issue
- 4
- Pages
- 629-636
- ISSN
- 0175-7598 (ISSN-L)
- 1432-0614
- OpenAlex
- W2047281856
- Cited by
- 1,116
- References
- 31
- Citations by year
- 2026: 18 · 2025: 24 · 2024: 30 · 2023: 47 · 2022: 52 · 2021: 61 · 2020: 78 · 2019: 76 · 2018: 81 · 2017: 91 · 2016: 98 · 2015: 86 · 2014: 103 · 2013: 94 · 2012: 74
- FWCI
- 19.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Applied Microbiology and Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Natural Sciences and Engineering Research Council of Canada
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Keywords
- Neochloris oleoabundans, nitrogen source, sodium nitrate, lipid accumulation, biomass productivity, cell growth, microalgae oil, biodiesel feedstock
- MeSH terms
- Chlorophyta, Chlorophyll, Nitrogen, Biomass, Lipid Metabolism
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