Brachial artery endothelial function in residents and fellows working night shifts
Abstract
Brachial artery endothelial function, which is measured as responsiveness to reactive hyperemia (flow-mediated dilation [FMD]) was abnormal in residents and house staff after a 24-hour shift, including night duty. The greatest decrease in FMD was observed in physicians with a longer history of night-shift duty and in those reporting fewer sleeping hours during the shift. The finding that FMD is decreased after night duty raises the issue of the effects of shift duty on cardiovascular function in healthcare personnel, particularly in those undertaking night duty for a prolonged period of time.
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Acute total sleep deprivation altered endothelial-dependent arterial and microvascular activities in healthy participants.
“Similarly, acute total sleep deprivation (TSD) also altered endothelial-dependent arterial [77] and microvascular activities [78] in healthy participants.”
From Association between sleep deficiency and cardiometabolic disease: implications for health disparities (2016) · cites this paper as [77]
Cites
Rozanski, A., Blumenthal, J. A., & Kaplan, J. (1999) · Circulation · doi:10.1161/01.cir.99.16.2192 · Cited by 2,846 · see citing works
Close Relation of Endothelial Function in the Human Coronary and Peripheral Circulations
Anderson, T. J., Uehata, A., Gerhard, M. D., Meredith, I. T., Knab, S., Delagrange, D., Lieberman, E. H., Ganz, P., Creager, M. A., Yeung, A. C., et al. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(95)00327-4 · Cited by 2,033 · see citing works
Vita, J. A., & Keaney, J. F. (2002) · Circulation · doi:10.1161/01.cir.0000028581.07992.56 · Cited by 743 · see citing works
Mental Stress Induces Transient Endothelial Dysfunction in Humans
Ghiadoni, L., Donald, A. E., Cropley, M., Mullen, M. J., Oakley, G. R., Taylor, M., O'Connor, G. M. F. A. C. M., Betteridge, J. D., Klein, N. J., Steptoe, A., et al. (2000) · Circulation · doi:10.1161/01.cir.102.20.2473 · Cited by 669 · see citing works
Prospective study of shift work and risk of coronary heart disease in women
Kawachi, I., Colditz, G. A., Stampfer, M. J., Willett, W. C., Manson, J. E., Speizer, F. E., & Hennekens, C. H. (1995) · Circulation · doi:10.1161/01.cir.92.11.3178 · Cited by 524 · see citing works
Endothelial function and nitric oxide: clinical relevance
Vallance, P. J., & Chan, N. N. (2001) · Heart · doi:10.1136/heart.85.3.342 · Cited by 389 · see citing works
Technical aspects of evaluating brachial artery vasodilatation using high-frequency ultrasound
Corretti, M. C., Plotnick, G. D., & Vogel, R. A. (1995) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1995.268.4.h1397 · Cited by 283 · see citing works
HASHIMOTO, M., Kozaki, K., Eto, M., Akishita, M., Ako, J., Iijima, K., Kim, S., Toba, K., Yoshizumi, M., & Ouchi, Y. (2000) · Hypertension Research · doi:10.1291/hypres.23.233 · Cited by 72 · see citing works
Bøttcher, M., Madsen, M. M., Refsgaard, J. C., Buus, N. H., Dørup, I., Nielsen, T. T., & Sørensen, K. E. (2001) · Circulation · doi:10.1161/01.cir.103.8.1109 · Cited by 72 · see citing works
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Shift work and cardiovascular disease – pathways from circadian stress to morbidity
Puttonen, S., Härmä, M., & Hublin, C. (2010) · Scandinavian Journal of Work, Environment & Health · doi:10.5271/sjweh.2894 · Cited by 560 · see citing works
Effect of acute sleep deprivation on vascular function in healthy subjects
Sauvet, F., Leftheriotis, G., Gomez-Merino, D., Langrume, C., Drogou, C., Van Beers, P., Bourrilhon, C., Florence, G., & Chennaoui, M. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00851.2009 · Cited by 268 · see citing works
Reed, D. A., Fletcher, K. E., & Arora, V. M. (2010) · Annals of Internal Medicine · doi:10.7326/0003-4819-153-12-201012210-00010 · Cited by 149 · see citing works
Experimental sleep restriction causes endothelial dysfunction in healthy humans
Calvin, A. D., Covassin, N., Kremers, W. K., Adachi, T., Macedo, P., Albuquerque, F. N., Bukartyk, J., Davison, D. E., Levine, J. A., Singh, P., et al. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.114.001143 · Cited by 123 · see citing works
Rangaraj, V. R., & Knutson, K. L. (2016) · Sleep Medicine · doi:10.1016/j.sleep.2015.02.535 · Cited by 120 · see citing works
Atherosclerotic risk and social jetlag in rotating shift-workers: First evidence from a pilot study
Kantermann, T., Duboutay, F., Haubruge, D., Kerkhofs, M., Schmidt-Trucksäss, A., & Skene, D. J. (2013) · Work · doi:10.3233/wor-121531 · Cited by 55 · see citing works
Apneic Sleep, Insufficient Sleep, and Hypertension
Mansukhani, M. P., Covassin, N., & Somers, V. K. (2019) · Hypertension · doi:10.1161/hypertensionaha.118.11780 · Cited by 52 · see citing works
Circadian clocks, obesity and cardiometabolic function
Scott, E. M. (2015) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.12518 · Cited by 25 · see citing works
- Authors
- Amir, O., Alroy, S., Schliamser, J. E., Asmir, I., Shiran, A., Flugelman, M. Y., Halon, D. A., & Lewis, B. S.
- Affiliations
- Technion – Israel Institute of Technology (IL)
- Corresponding author
- Lewis, Basil S.
- ORCID
- Venue
- The American Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2004-04
- Volume
- 93
- Issue
- 7
- Pages
- 947-949
- ISSN
- 0002-9149 (ISSN-L)
- OpenAlex
- W2127475663
- Cited by
- 92
- References
- 9
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 5 · 2023: 2 · 2021: 6 · 2020: 4 · 2019: 2 · 2018: 5 · 2017: 5 · 2016: 4 · 2015: 8 · 2014: 5 · 2013: 7 · 2012: 7
- FWCI
- 5.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Emergency Medicine › Hospital Admissions and Outcomes
- Keywords
- brachial artery endothelial function, flow-mediated dilation, reactive hyperemia, night shift work, shift work, physicians, medical residents, house staff, sleep duration, cardiovascular function, vascular dysfunction
- MeSH terms
- Adult, Brachial Artery, Endothelium, Vascular, Female, Humans, Hyperemia, Internship and Residency, Life Style, Male, Middle Aged, Stress, Physiological, Ultrasonography, Vasodilation, Work Schedule Tolerance
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