Apneic Sleep, Insufficient Sleep, and Hypertension
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The temporal distribution, night-to-night variability, and degree of desaturation or autonomic response associated with sleep-disordered breathing events may affect an individual's risk of developing hypertension.
“Finally, the temporal distribution, night-to-night variability, and degree of desaturation and/or autonomic response associated with SDB events may ultimately affect an individual’s risk of developing HTN.681”
From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [681]
Among adverse cardiovascular consequences, the evidence linking OSA and hypertension is the most robust.
“While OSA has been associated with several adverse CV consequences, the evidence linking OSA and HTN is the most robust.680,681”
From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [681]
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Self-citation
Flagged first, then by citations
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International Consensus Statement on Obstructive Sleep Apnea
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Hypertension and Cognitive Decline: Implications of Obstructive Sleep Apnea
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Extended afternoon naps are associated with hypertension in women but not in men
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“Moreover, 70% use is also inadequate as nondipping of BP and increased sympathetic tone on average of 8 nights per month can still have a protracted effect, as the effect on vasculature is effectively plastic [51].”
BackgroundAssociation between night sleep latency and hypertension: A cross-sectional study
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“29 Insomnia is regarded as a state of hyperarousal, with changes in hormonal balance, increased sympathetic activity, and hypothalamus-pituitary-adrenal axis activation, leading to metabolic changes and hypertension.”
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“health benefits, including cardiovascular abnormalities (8), hypertension (9), diabetes (10), and a higher risk of death (11).”
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“sleep problems and prevalence or incidence of HTN(36,37).”
Profile of gut flora in hypertensive patients with insufficient sleep duration
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“In brief, a large body of evidence comprising longitudinal and cross-sectional studies reveals an increased risk of hypertension in individuals with insufficient sleep (3, 9, 10).”
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“24,25 It is possible that the neuropsychiatric side effects and detrimental sleep qualify effects of EFV contributed to the increased risk of HTN observed in our analysis.”
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“Additionally, unhealthy sleep is associated with obesity, diabetes, and hypertension, which are established independent risk factors for CKD [46–48].”
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“S3E ; Supplementary Data 6).”
InfluentialHealthy Sleep Pattern, Metabolic Diseases, and Risk of Stroke: The Kailuan Cohort Study
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“13,36 3–5,37–39 However, the moderate mediation proportion (21.9”
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“[29] The Pennsylvania State University dataset showed that insomniacs who slept 5 hours had a five-fold greater risk of developing hypertension than did those who slept normally, whereas insomnia with a normal sleep schedule did not portend a significant increase in risk.”
Quality of life and psychological comorbidities in patients with migraine and hypertension
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Relationship Between Sleep and Hypertension: A Narrative Review
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Cardiovascular Benefits of Continuous Positive Airway Pressure: The Quest Continues…
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“…nighttime SBP and DBP further support the International Journal of Hypertension hypothesis that sleep disturbances associated with OSA negatively impact nocturnal BP regulation [100], a critical fnding given the importance of nighttime BP as a predictor of long-term cardiovascular outcomes [101].”
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“The STOP-Bang questionnaire includes both subjective and objective parameters and is used for screening of patients with significant risk of OSA.13 Subjective parameters are used to assess the history of snoring, observed apnea, and tiredness whereas objective parameters includes body mass index, blood pressure, neck…”
BackgroundInfluentialHarnessing the power of a good night's sleep
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Relationship Between Hypertension and Sleep: An Overview
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Research Progress in Renal Injury in Hypertensive Patients with Sleep Apnea Hypopnea Syndrome
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“…breathing, and decreased sleep quality are associated with higher daytime blood pressure and an increased risk of incident hypertension, 23 whereas pregnancy-related research has mostly focused on the effects of late-pregnancy sleep on the occurrence of preeclampsia or gestational…”
- Authors
- Mansukhani, M. P., Covassin, N., & Somers, V. K.
- Affiliations
- Mayo Clinic (US)
- Venue
- Hypertension
- Published
- 2019-04
- Volume
- 73
- Issue
- 4
- Pages
- 744-756
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- PMC
- PMC6513351
- OpenAlex
- W2916154289
- Semantic Scholar
- 16326b8914e0ef3c3fe60080b89c78c1f0cf4487
- Cited by
- 52
- References
- 227
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 3 · 2023: 4 · 2022: 14 · 2021: 8 · 2020: 10 · 2019: 3
- FWCI
- 1.03
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Hypertension (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R01HL134808, R01HL065176, R01HL134885)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Keywords
- insufficient sleep, sleep-disordered breathing, sleep deprivation
- MeSH terms
- Blood Pressure, Humans, Hypertension, Risk Factors, Sleep, Sleep Apnea, Obstructive, Vascular Stiffness
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