Cited by 40Traumatic Brain Injury ResearchLong-Term Effects of COVID-19Medical Practices and Rehabilitation

Feasibility of Concussion Rehabilitation Approaches Tailored to Psychological Coping Styles: A Randomized Controlled Trial

Silverberg, Noah D., Cairncross, Molly, Brasher, Penelope M.A., Vranceanu, Ana-Maria, Snell, Deborah L., Yeates, Keith Owen, Panenka, William J., Iverson, Grant L. +5 more·2022·Archives of Physical Medicine and Rehabilitation

Abstract

Objective To evaluate the feasibility of a clinical trial involving participants with concussion randomized to treatments designed to address fear avoidance or endurance coping, which are risk factors for disability. A secondary objective was to evaluate whether each treatment could affect selective change on targeted coping outcomes.Design Randomized controlled trial.Setting Outpatient concussion clinics.Participants Adults (N=73, mean age=42.5y) who had persistent postconcussion symptoms and high avoidance or endurance behavior were enrolled at a mean of 12.9 weeks post injury. Ten participants did not complete treatment.Interventions Participants were randomized to an interdisciplinary rehabilitation program delivered via videoconferencing and tailored to avoidance coping (graded exposure therapy [GET]) or endurance coping (operant condition-based pacing strategies plus mindfulness training [Pacing+]).Main outcome measures Feasibility outcomes included screening efficiency, accrual, credibility, treatment fidelity, adherence, and retention. Avoidance was measured with the Fear Avoidance Behavior after Traumatic Brain Injury Questionnaire and endurance behavior with the Behavioral Response to Illness Questionnaire.Results Screening efficiency, or the proportion of clinic patients who were assessed for eligibility, was 44.5% (275 of 618). A total of 65.8% (73 of 111) of eligible patients were randomized (37 to GET, 36 to Pacing+), meeting accrual targets; 91.7% (55 of 60) of participants perceived treatment as credible. Therapists covered a mean of 96.8% of essential prescribed elements, indicating excellent fidelity. The majority (71.2%; 47 of 66) of participants consistently attended treatment sessions and completed between-session homework. Retention was strong, with 65 of 73 (89%) randomized participants completing the outcome assessment. GET was associated with greater posttreatment reductions in avoidance behavior compared with Pacing+ (Cohen's d repeated measures, 0.81), whereas the treatment approach-specific effect of Pacing+ on endurance behavior was less pronounced (Cohen's d repeated measures, 0.39).Conclusions These findings support a future efficacy-focused clinical trial. GET has the potential to selectively reduce fear avoidance behavior after concussion, and, via this mechanism, to prevent or reduce disability.

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Crossref · 10.1016/j.apmr.2021.12.005

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Authors
Silverberg, N. D., Cairncross, M., Brasher, P. M. A., Vranceanu, A.-M., Snell, D. L., Yeates, K. O., Panenka, W. J., Iverson, G. L., Debert, C. T., Bayley, M. T., Hunt, C., Baker, A., & Burke, M. J.
Affiliations
  • University of British Columbia (CA)
  • Vancouver Coastal Health Research Institute (CA)
  • Harvard University (US)
  • Canterbury District Health Board (NZ)
  • University of Calgary (CA)
  • University Health Network (CA)
  • St. Michael's Hospital (CA)
  • Sunnybrook Health Science Centre (CA)
Corresponding author
Silverberg, Noah D.
Venue
Archives of Physical Medicine and Rehabilitation
Publisher
Elsevier BV
Published
2022-08
Volume
103
Issue
8
Pages
1565-1573.e2
ISSN
0003-9993 (ISSN-L)
OpenAlex
W4200032830
Cited by
40
References
68
Citations by year
2026: 4 · 2025: 14 · 2024: 10 · 2023: 8 · 2022: 4
FWCI
3.96
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Physical Medicine and Rehabilitation (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Michael Smith Foundation for Health Research
  • Alberta Children's Hospital Foundation
  • NFL Foundation
  • Spaulding Research Institute
  • Canadian Institutes of Health Research
  • National Football League Players Association
Topics
  • Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
  • Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Medical Practices and Rehabilitation
Keywords
concussion, post-concussion symptoms, fear avoidance, pacing strategy, mindfulness training, interdisciplinary rehabilitation, videoconferencing, intervention fidelity, trial feasibility, treatment retention, medication adherence
MeSH terms
Adaptation, Psychological, Adult, Brain Concussion, Feasibility Studies, Humans, Surveys and Questionnaires, Post-Concussion Syndrome

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