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Mitochondrial dysfunction and oxidative stress in metabolic disorders - A step towards mitochondria based therapeutic strategies
Open accessAbstract
Mitochondria are the powerhouses of the cell and are involved in essential functions of the cell, including ATP production, intracellular Ca 2+ regulation, reactive oxygen species production & scavenging, regulation of apoptotic cell death and activation of the caspase family of proteases. Mitochondrial dysfunction and oxidative stress are largely involved in aging, cancer, age-related neurodegenerative and metabolic syndrome. In the last decade, tremendous progress has been made in understanding mitochondrial structure, function and their physiology in metabolic syndromes such as diabetes, obesity, stroke and hypertension, and heart disease. Further, progress has also been made in developing therapeutic strategies, including lifestyle interventions (healthy diet and regular exercise), pharmacological strategies and mitochondria-targeted approaches. These strategies were mainly focused to reduce mitochondrial dysfunction and oxidative stress and to maintain mitochondrial quality in metabolic syndromes. The purpose of our article is to highlight the recent progress on the mitochondrial role in metabolic syndromes and also summarize the progress of mitochondria-targeted molecules as therapeutic targets to treat metabolic syndromes. This article is part of a Special Issue entitled: Oxidative Stress and Mitochondrial Quality in Diabetes/Obesity and Critical Illness Spectrum of Diseases - edited by P. Hemachandra Reddy.
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“mitochondrial dysfunction is both a cause and a consequence of metabolic disorders (Bhatti et al., 2017).”
From Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact (2020) · cites this paper as Bhatti et al., 2017
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“A significant amount of ROS formed during mitochondrial dysfunction significantly contributes to the incidence of cardiovascular diseases (Bhatti et al. 2017).”
From Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging (2023) · cites this paper as Bhatti et al. 2017
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Citations
Cites
Free radicals in biology and medicine
Gutteridge, J. M. C. (1991) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178
Mootha, V. K., Lindgren, C. M., Eriksson, K.-F., Subramanian, A., Sihag, S., Lehar, J., Puigserver, P., Carlsson, E., Ridderstråle, M., Laurila, E., et al. (2003) · Nature Genetics · doi:10.1038/ng1180 · Cited by 10,197
Free Radicals in the Physiological Control of Cell Function
Dröge, W. (2002) · Physiological Reviews · doi:10.1152/physrev.00018.2001 · Cited by 9,855
Oxidants, oxidative stress and the biology of ageing
Finkel, T., & Holbrook, N. J. (2000) · Nature · doi:10.1038/35041687 · Cited by 9,413
Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association
Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Beaton, A. Z., Boehme, A. K., Buxton, A. E., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001123 · Cited by 8,300
How mitochondria produce reactive oxygen species
Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207
Free radicals, metals and antioxidants in oxidative stress-induced cancer
Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M., & Mazur, M. (2006) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2005.12.009 · Cited by 6,680
Mitochondrial Dysfunction and Oxidative Stress in Neurodegenerative Diseases
Lin, M. T., & Beal, M. F. (2006) · Nature · doi:10.1038/nature05292 · Cited by 6,455
Heart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association
Roger, V. L., Go, A. S., Lloyd-Jones, D. M., Adams, R. J., Berry, J. D., Brown, T. M., Carnethon, M. R., Dai, S., de Simone, G., Ford, E. S., et al. (2011) · Circulation · doi:10.1161/cir.0b013e3182009701 · Cited by 6,149
Increased oxidative stress in obesity and its impact on metabolic syndrome
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508
Cited by
Sorted by citations
Items 201–300 of 999
Yang, J., Guo, Y., Henning, S. M., Chan, B. C., Long, J., Zhong, J., Acín‐Pérez, R., Petcherski, A., Shirihai, O. S., Heber, D., et al. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202000091 · Cited by 54
Nyunt, T., Britton, M., Wanichthanarak, K., Budamagunta, M. S., Voss, J. C., Wilson, D. W., Rutledge, J. C., & Aung, H. H. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.07.024 · Cited by 51
Deciphering the mechanisms, biochemistry, physiology, and social habits in the process of aging
Asejeje, F. O., & Ogunro, O. B. (2023) · Archives of Gerontology and Geriatrics Plus · doi:10.1016/j.aggp.2023.100003 · Cited by 58
Zhou, H., Wu, C., Jin, Y., Wu, O., Chen, L., Guo, Z., Xinzhou, W., Chen, Q., Kwan, K. Y.-H., Li, Y. M., et al. (2024) · Journal of Orthopaedic Translation · doi:10.1016/j.jot.2024.08.016 · Cited by 60
Redox control of non-shivering thermogenesis
Lettieri‐Barbato, D. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.04.002 · Cited by 52
Mo, F., Tang, Y., Du, P. F., Shen, Z., Yang, J., Cai, M., Zhang, Y., Li, H., & Shen, H. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.03.137 · Cited by 51
Winiarska‐Mieczan, A., Tomaszewska, E., & Jachimowicz-Rogowska, K. (2021) · Nutrients · doi:10.3390/nu13113972 · Cited by 51
Common methods in mitochondrial research (Review)
Yin, Y., & Shen, H. (2022) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2022.5182 · Cited by 52
Reframing the link between metabolism and NLRP3 inflammasome: therapeutic opportunities
Ortega, M. A., León-Oliva, D. D., Montero, C. G., Fraile‐Μartinez, O., Boaru, D. L., de Castro, A. V., Sáez, M. A., López-González, L., Buján, J., Álvarez-Mon, M. Á., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1232629 · Cited by 58
Zhang, R., Zhang, L., Ran, H., Li, P., Huang, J., Tan, M., Yang, Y., & Wang, Z. (2020) · Biomaterials Science · doi:10.1039/d0bm00408a · Cited by 50
Yan, L., Peng, X., Hu, Y., Xue, M., Li, T., Liu, L., & Yang, G. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/4132785 · Cited by 49
Fuller, K. N. Z., McCoin, C. S., Schulze, A. T. V., Houchen, C. J., Choi, M., & Thyfault, J. P. (2021) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00013.2021 · Cited by 45
Dobson, G. P., Morris, J. L., & Letson, H. L. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.968453 · Cited by 51
Ra, K., Park, S. C., & Lee, B. C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24055053 · Cited by 55
Molecular mechanisms and therapeutic potential of icariin in the treatment of Alzheimer's disease
Zheng, L., Wu, S., Jin, H., Wu, J., Wang, X., Cao, Y., Zhou, Z., Jiang, Y., Li, L., Yang, X., et al. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154890 · Cited by 48
Gál, R., Halmosi, R., Gallyas, F., Tschida, M., Mutirangura, P., Tóth, K., Alexy, T., & Czopf, L. (2023) · Biomedicines · doi:10.3390/biomedicines11112888 · Cited by 58
Clemente‐Suárez, V. J., Martín-Rodríguez, A., Beltrán-Velasco, A. I., Rubio-Zarapuz, A., Martínez‐Guardado, I., Valcárcel‐Martín, R., & Tornero-Aguilera, J. F. (2025) · Antioxidants · doi:10.3390/antiox14060725 · Cited by 70
Xu, D., Jiang, Z., Sun, Z., Wang, L., Zhao, G., Hassan, H. M., Fan, S., Zhou, W., Han, S., Zhang, L., et al. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27512 · Cited by 50
Natural products: Potential therapeutic agents to prevent skeletal muscle atrophy
Yadav, A., Yadav, S. S., Singh, S., & Dabur, R. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.174995 · Cited by 54
Lanzillotta, C., Tramutola, A., Di Giacomo, G., Marini, F., Butterfield, D. A., Di Domenico, F., Perluigi, M., & Barone, E. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.01.042 · Cited by 47
Fullerenol protects cornea from ultraviolet B exposure
Chen, X., Yang, J., Li, M., Zhu, S., Zhao, M., Cao, Y., Liu, B., Gao, H., Lu, A., Ge, L., et al. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102360 · Cited by 49
Aran, K. R., & Singh, S. (2023) · Aging and Health Research · doi:10.1016/j.ahr.2023.100169 · Cited by 48
Ortega, M. A., Fraile‐Μartinez, O., León-Oliva, D. D., Boaru, D. L., López-González, L., Montero, C. G., Álvarez-Mon, M. Á., Guijarro, L. G., Torres‐Carranza, D., Sáez, M. A., et al. (2024) · International Journal of Biological Sciences · doi:10.7150/ijbs.95122 · Cited by 54
Rebollo‐Hernanz, M., Zhang, Q., Aguilera, Y., Martin-Cabrejas, M. A., & de Mejı́a, E. G. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201801413 · Cited by 49
Líšková, A., Samec, M., Koklesová, L., Kúdela, E., Kubatka, P., & Golubnitschaja, O. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22042007 · Cited by 48
Cioffi, F., Giacco, A., Petito, G., Matteis, R. D., Senese, R., Lombardi, A., de Lange, P., Moreno, M., Goglia, F., Lanni, A., et al. (2022) · Genes · doi:10.3390/genes13020315 · Cited by 49
Standpoints in mitochondrial dysfunction: Underlying mechanisms in search of therapeutic strategies
Videla, L. A., Mariman, A. P., Ramos, B., Silva, M. J., & del Campo, A. (2022) · Mitochondrion · doi:10.1016/j.mito.2021.12.006 · Cited by 54
Li, Y., Li, X., Chu, Q., Jia, R., Chen, W., Wang, Y., Yu, X., & Zheng, X. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.12.218 · Cited by 48
Effect of Panax notoginseng Saponins and Major Anti-Obesity Components on Weight Loss
Zhang, X., Zhang, B., Zhang, C., Sun, G., & Sun, X. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.601751 · Cited by 49
Mishra, A., Wang, Y., Yin, F., Vitali, F., Rodgers, K. E., Soto, M., Mosconi, L., Wang, T., & Brinton, R. D. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101542 · Cited by 48
Wang, J., Zhang, J., Yu, Z., Chung, S. K., & Xu, B. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102416 · Cited by 52
Nagayach, A., Bhaskar, R., Ghosh, S., Singh, D. K. K., Han, S. S., & Sinha, J. K. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102450 · Cited by 51
New Insights into Mitochondria in Health and Diseases
Li, Y., Zhang, H., Yu, C., Dong, X., Yang, F., Wang, M., Wen, Z., Su, M., Li, B., & Yang, L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189975 · Cited by 48
Rappeneau, V., Wilmes, L., & Touma, C. (2020) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2020.103555 · Cited by 47
Zhang, Z., Nam, H. K., Crouch, S., & Hatch, N. E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031140 · Cited by 46
Immunometabolism in the pathogenesis of vitiligo
Lyu, C., & Sun, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1055958 · Cited by 49
Xia, Y., Guan, Y.-Q., Liang, J., & Wu, W. (2024) · Renal Failure · doi:10.1080/0886022x.2024.2313176 · Cited by 48
Zhao, Y., Wu, Y., Zhang, X., Zhu, X., Hou, Y., Chen, J., Cui, K., Li, X., & Wu, W. (2024) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2024.113303 · Cited by 45
Mitophagy and Mitochondrial Quality Control Mechanisms in the Heart
Gottlieb, R. A., & Thomas, A. (2017) · Current Pathobiology Reports · doi:10.1007/s40139-017-0133-y · Cited by 50
Molecular and cellular bases of diabetes: Focus on type 2 diabetes mouse model-TallyHo
Tamarai, K., Bhatti, J. S., & Reddy, P. H. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2019.05.004 · Cited by 48
Self-citationCheng, Y., Mai, Q., Zeng, X., Wang, H., Xiao, Y., Tang, L., Li, J., Zhang, Y., & Ding, H. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.08.009 · Cited by 45
Epigenetic Remodeling in Obesity-Related Vascular Disease
Masi, S., Ambrosini, S., Mohammed, S. A., Sciarretta, S., Lüscher, T. F., Paneni, F., & Costantino, S. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8040 · Cited by 49
Naringin‐generated ROS promotes mitochondria‐mediated apoptosis in Candida albicans
Kim, H., & Lee, D. G. (2021) · IUBMB Life · doi:10.1002/iub.2476 · Cited by 44
Genetically Encoded ATP Biosensors for Direct Monitoring of Cellular ATP Dynamics
White, D., & Yang, Q. (2022) · Cells · doi:10.3390/cells11121920 · Cited by 48
Oxidative stress and metabolism meet epigenetic modulation in physical exercise
García‐Giménez, J. L., Cánovas‐Cervera, I., & Pallardó, F. V. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.01.008 · Cited by 50
Depression and obesity: Focus on factors and mechanistic links
Selman, A., Dai, J., Driskill, J., Reddy, A. P., & Reddy, P. H. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2024.167561 · Cited by 48
Self-citationHamamah, S., Iatcu, O. C., & Covașă, M. (2024) · Nutrients · doi:10.3390/nu17010143 · Cited by 52
Mitochondria: the hidden engines of traumatic brain injury-driven neurodegeneration
Olatona, O. A., Sterben, S. P., Kansakar, S. B. S., Symes, A. J., & Liaudanskaya, V. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2025.1570596 · Cited by 46
Sun, X., & Qiu, H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21113842 · Cited by 44
Dietary protein and amino acid restriction: Roles in metabolic health and aging-related diseases
Wang, D., Ye, J., Shi, R., Zhao, B., Liu, Z., Lin, W. J., & Liu, X. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.12.009 · Cited by 46
Docosahexaenoic Acid Alleviates Brain Damage by Promoting Mitophagy in Mice with Ischaemic Stroke
Sun, E., Zhang, J., Deng, Y., Wang, J., Wu, Q., Chen, W., Ma, X., Chen, S., Xiang, X., Chen, Y., et al. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/3119649 · Cited by 45
Kim, W. S., Kim, Y.-E., Cho, E.-J., Byun, E.-B., Park, W. Y., Song, H.-Y., Kim, K., Park, S.-H., & Byun, E.-H. (2020) · Bioscience, Biotechnology, and Biochemistry · doi:10.1080/09168451.2020.1715201 · Cited by 37
Paul, S. C., Saha, D., & Binukumar, B. K. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02365-2 · Cited by 43
Metabolomics in asthma: A platform for discovery
Xu, S., Panettieri, R. A., & Jude, J. A. (2021) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2021.100990 · Cited by 45
Leman, G., Pavel, P., Hermann, M., Crumrine, D. A., Elias, P. M., Minzaghi, D., Goudounèche, D., Prieto, N. M. R., Cavinato, M. S., Wanner, A., et al. (2022) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2022.01.035 · Cited by 43
Ozone Pollution, Oxidative Stress, Regulatory T Cells and Antioxidants
Rivas-Arancibia, S., Hernández-Orozco, E., Rodrı́guez-Martı́nez, E., Valdés‐Fuentes, M., Cornejo-Trejo, V., Pérez-Pacheco, N., Dorado-Martı́nez, C., Zequeida-Carmona, D., & Caleti, I. E. (2022) · Antioxidants · doi:10.3390/antiox11081553 · Cited by 45
Zhou, D. R., Eid, R., Miller, K. A., Boucher, É. L., Mandato, C. A., & Greenwood, M. T. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2019.01.016 · Cited by 43
Li, J., Wu, N., Cheng, X. J., Chen, H., Yang, X., & Liu, C. (2019) · Islets · doi:10.1080/19382014.2019.1690944 · Cited by 43
Szűcs, G., Sója, A., Péter, M., Sárközy, M., Bruszel, B., Siska, A., Földesi, I., Szabó, Z., Janáky, T., Vı́gh, L., et al. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/3218275 · Cited by 43
Wang, M., Wang, K., Deng, G., Liu, X., Wu, X., Hu, H., Zhang, Y., Gao, W., & Li, Q. (2020) · International Journal of Nanomedicine · doi:10.2147/ijn.s240301 · Cited by 42
Fang, C., Xu, H., Yuan, L., Zhu, Z., Wang, X., Liu, Y., Zhang, A., Shao, A., & Lou, M. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/1949718 · Cited by 46
The effect of chromium intake on oxidative stress parameters: A systematic review and meta-analysis
Morvaridzadeh, M., Estêvão, M. D., Qorbani, M., Heydari, H., Hoseini, A. S., Fazelian, S., Belančić, A., Persad, E., Rezamand, G., & Heshmati, J. (2021) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2021.126879 · Cited by 44
Mitochondrial Function and Reactive Oxygen/Nitrogen Species in Skeletal Muscle
Chen, M., Li, Y., Deng, S., Zhao, Y., Lian, Z., & Yu, K. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.826981 · Cited by 49
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Simon, L., & Molina, P. E. (2022) · Function · doi:10.1093/function/zqac039 · Cited by 45
Nandi, S., Sikder, R., Rapior, S., Arnould, S., Simal‐Gándara, J., & Acharya, K. (2023) · Fitoterapia · doi:10.1016/j.fitote.2023.105681 · Cited by 42
Tong, Z., Du, X., Zhou, Y., Jing, F., Ma, J., Feng, Y., Lou, S., Wang, Q. A., & Dong, Z. (2024) · Cellular Signalling · doi:10.1016/j.cellsig.2024.111075 · Cited by 42
Anghel, L., Ciubară, A., Pătraș, D., & Ciubară, A. B. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14061809 · Cited by 48
Baicalein decreases uric acid and prevents hyperuricemic nephropathy in mice
Meng, X., Mao, Z., Li, X., Zhong, D., Li, M., Jia, Y., Wei, J., Yang, B., & Zhou, H. (2017) · Oncotarget · doi:10.18632/oncotarget.16928 · Cited by 42
Chen, Y., Sung, H., Chuang, T., Lee, T.-L., Lee, C., Lee, I.-T., Lee, I.-T., & Chen, Y. (2021) · Cell Biology and Toxicology · doi:10.1007/s10565-021-09629-6 · Cited by 44
Souza‐Neto, F. V., Jiménez‐González, S., Delgado‐Valero, B., Jurado-López, R., Genty, M., Romero‐Miranda, A., Rodrı́guez, C., Nieto, M. L., Martínez‐Martínez, E., & Cachofeiro, V. (2021) · Antioxidants · doi:10.3390/antiox10081274 · Cited by 41
Potential of Sorghum Polyphenols to Prevent and Treat Alzheimer’s Disease: A Review Article
Rezaee, N., Fernando, W. M. A. D. B., Hone, E., Sohrabi, H. R., Johnson, S. K., Gunzburg, S. T., & Martins, R. N. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.729949 · Cited by 46
Mitochondrial Targeting and Imaging with Small Organic Conjugated Fluorophores: A Review
Crawford, H., Dimitriadi, M., Bassin, J. P., Cook, M. T., Abelha, T. F., & Calvo‐Castro, J. (2022) · Chemistry - A European Journal · doi:10.1002/chem.202202366 · Cited by 41
Bhatti, J. S., Thamarai, K., Kandimalla, R., Manczak, M., Yin, X., Kumar, S., Vijayan, M., & Reddy, P. H. (2021) · Molecular Neurobiology · doi:10.1007/s12035-020-02142-7 · Cited by 41
Self-citationOxidative Stress and Vascular Damage in the Context of Obesity: The Hidden Guest
Martínez‐Martínez, E., Souza‐Neto, F. V., Jiménez‐González, S., & Cachofeiro, V. (2021) · Antioxidants · doi:10.3390/antiox10030406 · Cited by 45
Ethalfluralin induces developmental toxicity in zebrafish via oxidative stress and inflammation
Hong, T., Park, H., An, G., Song, G., & Lim, W. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.158780 · Cited by 41
Pivotal role of vitamin D in mitochondrial health, cardiac function, and human reproduction
Reddy, A. M., Iqbal, M., Chopra, H., Urmi, S., Junapudi, S., Bibi, S., Gupta, S. K., Pangi, V. N., Singh, I., & Abdel‐Daim, M. M. (2022) · EXCLI journal · doi:10.17179/10.17179/excli2022-4935 · Cited by 47
Impact of Bisphenol A on Structure and Function of Mitochondria: A Critical Review
Nayak, D., Adiga, D., Khan, N. G., Rai, P. S., Dsouza, H. S., Chakrabarty, S., Gassman, N. R., & Kabekkodu, S. P. (2022) · Reviews of Environmental Contamination and Toxicology · doi:10.1007/s44169-022-00011-z · Cited by 44
Lipid bilayer-based biological nanoplatforms for sonodynamic cancer therapy
Li, S., Mok, G. S. P., & Dai, Y. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.115110 · Cited by 41
Second-generation antipsychotics and metabolic syndrome: a role for mitochondria
Mortimer, K. R. H., Katshu, M. Z. U. H., & Chakrabarti, L. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1257460 · Cited by 46
Feng, X., Qiu, F. X., Zheng, L., Zhang, Y., Wang, Y., Wang, M., Han, X., Tang, B., Yan, C., & Liang, R. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.172512 · Cited by 41
Sebghatollahi, Z., Yogesh, R., Mahato, N., Kumar, V., Mohanta, Y. K., Baek, K.-H., & Mishra, A. K. (2025) · Antioxidants · doi:10.3390/antiox14040457 · Cited by 46
Qiu, J., Li, J., Xu, S. M., Yang, J., Zeng, H., Zhang, Y., Yang, S., Fang, L., Huang, J., Zhou, H., et al. (2025) · Cardiovascular Diabetology · doi:10.1186/s12933-025-02873-8 · Cited by 45
Chung, E., Joiner, H. E., Skelton, T., Looten, K. D., Mańczak, M., & Reddy, P. H. (2017) · Physiological Reports · doi:10.14814/phy2.13184 · Cited by 42
Self-citationPeripheral modulation of the endocannabinoid system in metabolic disease
Shrestha, N., Cuffe, J. S. M., Hutchinson, D. S., Headrick, J. P., Perkins, A. V., McAinch, A. J., & Hryciw, D. H. (2018) · Drug Discovery Today · doi:10.1016/j.drudis.2018.01.029 · Cited by 43
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Metadata
- Authors
- Bhatti, J. S., Bhatti, G. K., & Reddy, P. H.
- Affiliations
- Sri Guru Gobind Singh College (IN)
- Panjab University (IN)
- Texas Tech University (US)
- Corresponding author
- Bhatti, Jasvinder Singh
- Venue
- Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 1863
- Issue
- 5
- Pages
- 1066-1077
- ISSN
- 0925-4439 (ISSN-L)
- PMC
- PMC5423868
- OpenAlex
- W2553902009
- Cited by
- 1,655
- References
- 238
- Citations by year
- 2026: 168 · 2025: 319 · 2024: 293 · 2023: 235 · 2022: 246 · 2021: 151 · 2020: 115 · 2019: 65 · 2018: 34 · 2017: 29
- FWCI
- 3.86
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH (AG042178, AG047812)
- Garrison Family Foundation
- University Grants Commission, India (5-82/2016)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Keywords
- mitochondrial dysfunction, oxidative stress, metabolic syndrome, mitochondrial-targeted therapy, reactive oxygen species, apoptosis, caspases, diabetes mellitus, obesity, hypertension, stroke, heart disease, mitochondrial quality, lifestyle intervention, pharmacotherapy
- MeSH terms
- Animals, Humans, Metabolic Diseases, Mitochondria, Oxidative Stress
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