The DOI matches its Crossref record; 236 of the 238 references it cites were found in a registry or an index.
Mitochondrial dysfunction and oxidative stress in metabolic disorders - A step towards mitochondria based therapeutic strategies
Open accessAbstract
Mitochondria are the powerhouses of the cell and are involved in essential functions of the cell, including ATP production, intracellular Ca 2+ regulation, reactive oxygen species production & scavenging, regulation of apoptotic cell death and activation of the caspase family of proteases. Mitochondrial dysfunction and oxidative stress are largely involved in aging, cancer, age-related neurodegenerative and metabolic syndrome. In the last decade, tremendous progress has been made in understanding mitochondrial structure, function and their physiology in metabolic syndromes such as diabetes, obesity, stroke and hypertension, and heart disease. Further, progress has also been made in developing therapeutic strategies, including lifestyle interventions (healthy diet and regular exercise), pharmacological strategies and mitochondria-targeted approaches. These strategies were mainly focused to reduce mitochondrial dysfunction and oxidative stress and to maintain mitochondrial quality in metabolic syndromes. The purpose of our article is to highlight the recent progress on the mitochondrial role in metabolic syndromes and also summarize the progress of mitochondria-targeted molecules as therapeutic targets to treat metabolic syndromes. This article is part of a Special Issue entitled: Oxidative Stress and Mitochondrial Quality in Diabetes/Obesity and Critical Illness Spectrum of Diseases - edited by P. Hemachandra Reddy.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“mitochondrial dysfunction is both a cause and a consequence of metabolic disorders (Bhatti et al., 2017).”
From Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact (2020) · cites this paper as Bhatti et al., 2017
In the citing paper
“A significant amount of ROS formed during mitochondrial dysfunction significantly contributes to the incidence of cardiovascular diseases (Bhatti et al. 2017).”
From Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging (2023) · cites this paper as Bhatti et al. 2017
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Free radicals in biology and medicine
Gutteridge, J. M. C. (1991) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178
Mootha, V. K., Lindgren, C. M., Eriksson, K.-F., Subramanian, A., Sihag, S., Lehar, J., Puigserver, P., Carlsson, E., Ridderstråle, M., Laurila, E., et al. (2003) · Nature Genetics · doi:10.1038/ng1180 · Cited by 10,197
Free Radicals in the Physiological Control of Cell Function
Dröge, W. (2002) · Physiological Reviews · doi:10.1152/physrev.00018.2001 · Cited by 9,855
Oxidants, oxidative stress and the biology of ageing
Finkel, T., & Holbrook, N. J. (2000) · Nature · doi:10.1038/35041687 · Cited by 9,413
Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association
Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Beaton, A. Z., Boehme, A. K., Buxton, A. E., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001123 · Cited by 8,300
How mitochondria produce reactive oxygen species
Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207
Free radicals, metals and antioxidants in oxidative stress-induced cancer
Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M., & Mazur, M. (2006) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2005.12.009 · Cited by 6,680
Mitochondrial Dysfunction and Oxidative Stress in Neurodegenerative Diseases
Lin, M. T., & Beal, M. F. (2006) · Nature · doi:10.1038/nature05292 · Cited by 6,455
Heart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association
Roger, V. L., Go, A. S., Lloyd-Jones, D. M., Adams, R. J., Berry, J. D., Brown, T. M., Carnethon, M. R., Dai, S., de Simone, G., Ford, E. S., et al. (2011) · Circulation · doi:10.1161/cir.0b013e3182009701 · Cited by 6,149
Increased oxidative stress in obesity and its impact on metabolic syndrome
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508
Cited by
Sorted by citations
Items 501–600 of 999
Impairment of Neuronal Mitochondrial Quality Control in Prion-Induced Neurodegeneration
Kim, M., Kim, H., Jang, B., Kim, H., Mostafa, M. N., Park, S., Kim, Y., & Choi, E. (2022) · Cells · doi:10.3390/cells11172744 · Cited by 21
Parksepp, M., Haring, L., Kilk, K., Taalberg, E., Kangro, R., Zilmer, M., & Vasar, E. (2022) · Metabolites · doi:10.3390/metabo12100983 · Cited by 21
NFIXing Cancer: The Role of NFIX in Oxidative Stress Response and Cell Fate
Ribeiro, V., Martins, S. G., Lopes, A. S., Þorsteinsdóttir, S., Zilhão, R., & Carlos, A. R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054293 · Cited by 21
Exercise and vascular function in sedentary lifestyles in humans
Fasipe, B., Li, S., & Laher, I. (2023) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-023-02828-6 · Cited by 22
Duisenbek, A., López-Armas, G. D. C., Pérez, M., Perez, M. D., Benítez, J. M. A., Pérez, V. R. P., Ortega, J. G., Yessenbekova, A., Аблайханова, Н. Т., Escames, G., et al. (2023) · Antioxidants · doi:10.3390/antiox12061290 · Cited by 24
Rigotti, M., Cerbaro, A. F., Silva, I. D. R., Agostini, F., Branco, C. S., Moura, S., & Salvador, M. M. (2020) · Journal of Food Biochemistry · doi:10.1111/jfbc.13147 · Cited by 21
Yao, Y., & Lawrence, D. A. (2020) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.22626 · Cited by 22
Lim, J., Kim, J. S., Kim, H. W., Kim, Y. H., Jung, S. S., Kim, J. W., Oh, J. Y., Lee, H., Kim, S. K., Kim, S., et al. (2023) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofad422 · Cited by 22
Munteanu, C., Galaction, A., Onose, G., Turnea, M. A., & Rotariu, M. (2025) · Antioxidants · doi:10.3390/antiox14030360 · Cited by 20
Mir, F. A., Lark, A. R. S., & Nehs, C. J. (2025) · Frontiers in Aging · doi:10.3389/fragi.2025.1605070 · Cited by 23
Montenegro, K. R., Pufal, M. A., & Newsholme, P. (2021) · Nutrients · doi:10.3390/nu13041110 · Cited by 21
Fernandes, C., Videira, A. J. C., Veloso, C. D., Benfeito, S., Soares, P., Martins, J. D., Gonçalves, B., Duarte, J. F. S., Santos, A. M. S., Oliveira, P. J., et al. (2021) · Biomolecules · doi:10.3390/biom11111605 · Cited by 20
Immune and Metabolic Alterations in Liver Fibrosis: A Disruption of Oxygen Homeostasis?
Li, X., Zhang, Q., Wang, Z., Zhuang, Q., & Zhao, M. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.802251 · Cited by 22
Gao, F., Zhao, Y., Zhang, B., Xiao, C., Sun, Z., Gao, Y., & Dou, X. (2022) · Journal of Biomaterials Applications · doi:10.1177/08853282221087102 · Cited by 20
Sun, Y.-M., Wang, X.-Y., Zhou, X.-R., Zhang, C., Liu, K.-J., Zhang, F.-Y., & Xiang, B. (2022) · Antioxidants · doi:10.3390/antiox11071414 · Cited by 20
Hao, J., Liu, H., Wang, J., Wang, X., Huang, C., Liang, L., Chen, J., Wang, Y., & Liu, Y. (2022) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2022.111946 · Cited by 21
Wang, R., Santos, J. M., Dufour, J. M., Stephens, E. R., Miranda, J. M., Washburn, R. L., Hibler, T., Kaur, G., Lin, D., & Shen, C. (2022) · Nutrients · doi:10.3390/nu14204384 · Cited by 25
Ren, J., Wang, B., Li, L., Li, S., Ma, Y., Su, L., Liu, G., Liu, Y., & Dai, Y. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.114530 · Cited by 20
Li, K., Wan, B., Li, S., Chen, Z., Jia, H., Song, Y., Zhang, J., Ju, W., Ma, H., & Wang, Y. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1063556 · Cited by 21
Kobayashi, A., Takeiwa, T., Ikeda, K., & Inoue, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24119414 · Cited by 23
Robea, M. A., Balmuș, I.-M., Gîrleanu, I., Huiban, L., Muzica, C. M., Ciobica, A. S., Stanciu, C., Cimpoesu, C. D., & Trifan, A. V. (2023) · Medicina · doi:10.3390/medicina59091614 · Cited by 22
Mertens, J., Belva, F., van Montfoort, A. P. A., Regin, M., Zambelli, F., Seneca, S., de Deckersberg, E. C., Bonduelle, M., Tournaye, H. J., Stouffs, K., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-45446-1 · Cited by 21
The S. pombe mitochondrial transcriptome
Shang, J., Yang, Y., Wu, L., Zou, M., & Huang, Y. K. (2018) · RNA · doi:10.1261/rna.064477.117 · Cited by 19
Yang, C.-C., Wang, W., Lin, F., & Hou, C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20051148 · Cited by 20
McMurray, F., Macfarlane, M., Kim, K., Patten, D. A., Wei‐LaPierre, L., Fullerton, M. D., & Harper, M. (2019) · The FASEB Journal · doi:10.1096/fj.201901150r · Cited by 20
The Potential Roles of Ghrelin in Metabolic Syndrome and Secondary Symptoms of Alzheimer’s Disease
Kim, S., Nam, Y., Shin, S. J., Park, Y., Jeon, S. G., Kim, J.-I., Kim, M., & Moon, M. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.583097 · Cited by 20
Henderson, K. N., Killen, L. G., O'Neal, E. K., & Waldman, H. S. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18031105 · Cited by 21
Mazibuko-Mbeje, S. E., Mthembu, S. X. H., Dludla, P. V., Madoroba, E., Chellan, N., Kappo, A. P., & Muller, C. J. F. (2021) · Toxicology in Vitro · doi:10.1016/j.tiv.2021.105224 · Cited by 22
Use of Next-Generation Sequencing for Identifying Mitochondrial Disorders
Mahmud, S., Biswas, S., Afrose, S., Mita, M. A., Hasan, M. K., Shimu, M. S. S., Paul, G. K., Chung, S., Saleh, M. A., Alshehri, S., et al. (2022) · Current Issues in Molecular Biology · doi:10.3390/cimb44030074 · Cited by 23
Sweet Mitochondria: A Shortcut to Alzheimer’s Disease
Moreira, P. I. (2018) · Journal of Alzheimer’s Disease · doi:10.3233/jad-170931 · Cited by 20
Chavez, G. N., Jaworsky, K., & Basu, A. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20156534 · Cited by 22
Human Aging and Age-Related Diseases: From Underlying Mechanisms to Pro-Longevity Interventions
Chmielewski, P. P., Data, K., Strzelec, B., Farzaneh, M., Anbiyaiee, A., Zaheer, U., Uddin, S., Sheykhi-Sabzehpoush, M., Mozdziak, P. E., Zabel, M., et al. (2024) · Aging and Disease · doi:10.14336/ad.2024.0280 · Cited by 25
Kaur, A., & Aran, K. R. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.04.001 · Cited by 23
Liu, X., Li, Y., Wang, J., Meng, T., Song, L., Yang, L., Yu, J., & Ma, C. (2025) · Metabolic Brain Disease · doi:10.1007/s11011-025-01601-1 · Cited by 19
Nam, H., Park, H., Son, M. K., Kang, I., Choi, Y., Lee, S., Kim, S., Kim, S. R., Kim, H., Chang, J., et al. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.113775 · Cited by 19
Alzarea, E. A., Al-Kuraishy, H. M., Al-Gareeb, A. I., Alexiou, A. T., Papadakis, M., Beshay, O. N., & Batiha, G. E. (2025) · NeuroMolecular Medicine · doi:10.1007/s12017-025-08832-6 · Cited by 21
Fan, Y., Zhao, H., Lu, L., & Wu, W. (2025) · Nutrients · doi:10.3390/nu17111855 · Cited by 21
The role of mitochondrial dysfunction in ovarian granulosa cells in polycystic ovary syndrome
Yan, X., Ma, D., Li, R., Xu, J., Zou, Y., & He, M. (2025) · Endocrine Connections · doi:10.1530/ec-25-0186 · Cited by 19
Vitiligo: The Association With Metabolic Syndrome and the Role of Simvastatin as an Immunomodulator
Verma, D., Hussain, K., Namiq, K. S., Firoz, A., Bouchama, M., Raza, M., Haris, M., & Khan, S. (2021) · Cureus · doi:10.7759/cureus.14029 · Cited by 19
Ca2+ Dyshomeostasis Links Risk Factors to Neurodegeneration in Parkinson’s Disease
Xu, J., Minobe, E., & Kameyama, M. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.867385 · Cited by 20
Figueiredo-Junior, A. T., Valença, S. S., Finotelli, P. V., dos Anjos, F. D. F., de Brito‐Gitirana, L., Takiya, C. M., & Lanzetti, M. (2022) · Antioxidants · doi:10.3390/antiox11071293 · Cited by 20
Salman, M., Akram, M. V., Shahrukh, M., Ishrat, T., & Parvez, S. (2022) · NeuroToxicology · doi:10.1016/j.neuro.2022.07.006 · Cited by 19
Zhao, T., Alder, N. N., Starkweather, A. R., Chen, M., Matson, A. P., Xu, W., Balsbaugh, J. L., & Cong, X. S. (2022) · Developmental Neuroscience · doi:10.1159/000526491 · Cited by 20
Liu, T., Wang, L., Chen, G., Tong, L., Ye, X., Yang, H. M., Liu, H., Zhang, H., Lu, W., Zhang, S., et al. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106173 · Cited by 20
Guerrero‐Wyss, M., Yans, C., Boscan, A., Durán, P., Parra-Soto, S. L., & Angarita, L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241310779 · Cited by 19
Hu, J., Xu, L., Panga, M. J., Appiah, C., Retyunskiy, V., Zhu, L., & Zhao, Y. (2023) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2023.132575 · Cited by 19
Arjmand, S., Ilaghi, M., Sisakht, A. K., Guldager, M. B., Wegener, G., Landau, A. M., & GJEDDE, A. H. (2024) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.14035 · Cited by 23
The Dual Burden: Exploring Cardiovascular Complications in Chronic Kidney Disease
Caturano, A., Galiero, R., Rocco, M. P., Tagliaferri, G., Piacevole, A., Nilo, D., Lorenzo, G. D., Sardu, C., Russo, V., Vetrano, E., et al. (2024) · Biomolecules · doi:10.3390/biom14111393 · Cited by 25
Adrenic acid: A promising biomarker and therapeutic target (Review)
Wang, Z., Gao, H., Ma, X., Zhu, D., Zhao, L., & Xiao, W. (2024) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2024.5461 · Cited by 21
p62/sequestosome-1 knockout delays neurodegeneration induced by Drp1 loss
Yamada, T., Adachi, Y., Yanagawa, T., Iijima, M., & Sesaki, H. (2017) · Neurochemistry International · doi:10.1016/j.neuint.2017.05.012 · Cited by 18
Tan, B. L., Norhaizan, M. E., & Chan, L. C. (2018) · Pharmaceutics · doi:10.3390/pharmaceutics10040198 · Cited by 19
Bourebaba, L., Bedjou, F., Röcken, M., & Marycz, K. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1292-z · Cited by 19
Filippov, M. A., Tatarnikova, O. G., Pozdnyakova, N. V., & Vorobyov, V. (2020) · Neural Regeneration Research · doi:10.4103/1673-5374.290878 · Cited by 21
The Influence of Obesity and Associated Fatty Acids on Placental Inflammation
Eastman, A. J., Moore, R. E., Townsend, S. D., Gaddy, J. A., & Aronoff, D. M. (2021) · Clinical Therapeutics · doi:10.1016/j.clinthera.2020.12.018 · Cited by 24
Relationships Between Aerobic Fitness Levels and Cognitive Performance in Swedish Office Workers
Pantzar, A., Jonasson, L. S., Ekblom, Ö. B., Boraxbekk, C., & Ekblom, M. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.02612 · Cited by 21
Jiang, S., Hao, B., Song, X., Jiang, Y., Guo, J., Wang, Y., Wang, Q., Wang, X., Xu, T., Wu, X., et al. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202403866 · Cited by 18
Nutraceutical Strategies for Targeting Mitochondrial Dysfunction in Neurodegenerative Diseases
Davì, F., Iaconis, A., Cordaro, M., Paola, R. D., & Fusco, R. (2025) · Foods · doi:10.3390/foods14132193 · Cited by 20
Type 3 Diabetes: Linking Insulin Resistance to Cognitive Decline
Chapple, B. E., Bayliss, E., Woodfin, S., Smith, M., Winter, J., & Moore, W. (2025) · Diseases · doi:10.3390/diseases13110359 · Cited by 22
Zhu, S., Chen, C., Wu, Y. N., Ahmed, M., Kitmitto, A., Greenstein, A. S., Kim, S. J., Shao, Y., & Zhang, Y. H. (2020) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-020-02355-8 · Cited by 18
Albini, A., Festa, M., Ring, N., Baci, D., Rehman, M., Finzi, G., Sessa, F., Zacchigna, S., Bruno, A., & Noonan, D. M. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.694762 · Cited by 18
Antioxidant Mitoquinone Alleviates Chronic Pancreatitis via Anti-Fibrotic and Antioxidant Effects
Li, M., Yuan, Y., Han, X., Liu, X., Zhang, W., & Hao, J. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s357394 · Cited by 18
Sriwichaiin, S., Apaijai, N., Phrommintikul, A., Jaiwongkam, T., Kerdphoo, S., Pratchayasakul, W., Thongmung, N., Mahantassanapong, U., Vathesatogkit, P., Kitiyakara, C., et al. (2022) · The Journals of Gerontology Series A · doi:10.1093/gerona/glac201 · Cited by 18
He, L., & Maheshwari, A. (2022) · Current Pediatric Reviews · doi:10.2174/1573396319666221221110728 · Cited by 17
Khatun, M., Lundin, K., Naillat, F., Loog, L., Saarela, U., Tuuri, T., Salumets, A., Piltonen, T., & Tapanainen, J. S. (2023) · Stem Cell Reviews and Reports · doi:10.1007/s12015-023-10627-w · Cited by 20
Qi, X., Liu, C., Si, J., Yin, B., Huang, J., Wang, X., Huang, J., Sun, H. M., Zhu, C., & Zhang, W. (2024) · Cell Proliferation · doi:10.1111/cpr.13613 · Cited by 17
Dysfunctional mitochondria elicit bioenergetic decline in the aged heart
Mone, P., Agyapong, E. D., Morciano, G., Jankauskas, S. S., Luca, A. D., Varzideh, F., Pinton, P., & Santulli, G. (2024) · The Journal of Cardiovascular Aging · doi:10.20517/jca.2023.50 · Cited by 19
Viebahn-Haensler, R., & Fernández, O. (2024) · Molecules · doi:10.3390/molecules29122738 · Cited by 18
Ccrn4l as a pre-dose marker for prediction of cisplatin-induced hepatotoxicity susceptibility
Hwang, D., Won, D., Shin, Y. S., Kim, S.-Y., Kang, B.-C., Lim, K., Che, J., Nam, K. T., & Yun, J.-W. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.01.003 · Cited by 18
Trinity, J. D., Drummond, M. J., Fermoyle, C. C., McKenzie, A. I., Supiano, M. A., & Richardson, R. S. (2022) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00607.2021 · Cited by 18
Munakarmi, S., Gurau, Y., Shrestha, J., Risal, P., Park, H. S., Shin, H. B., & Jeong, Y. J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911407 · Cited by 18
EXPRESSION OF CONCERN: Mitophagy protects against statin‐mediated skeletal muscle toxicity
Ramesh, I., Campos, J. C., Lee, P., Song, Y., Hernandez, G., Sin, J., Tucker, K. C., Saadaeijahromi, H., Gurney, M., Ferreira, J. C. B., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201900807rr · Cited by 17
Fu, L., Wang, S., Zhang, N., Lin, Y., Zhang, S., Mao, Y., & Zhou, P. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.158540 · Cited by 17
He, Y., Liu, T., Peng, X., Yao, C., Zhou, D., Song, C., Wei, Z., Chen, J., Liu, Z., & Jiang, F. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2025.167685 · Cited by 18
Algal and Fungal Antioxidants Alleviate Oxidative Stress‐Induced Reproductive Defects
Arslan, N. P., Albayrak, S., Savaş, A., Hacımüftüoğlu, A., Orak, T., Ozdemir, A., Karadagoglu, O., Yildirim, S., Yılmaz, H. Ç., & Taşkın, M. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70301 · Cited by 19
Wang, M., Yang, Q., Li, Y., Zhao, Y., Zou, J., Luan, F., Peng, X., Huang, Z., & Liu, F. (2025) · Chinese Medicine · doi:10.1186/s13020-025-01222-x · Cited by 17
Singh, P. N. D., Mishra, G., Molla, M., Yimer, Y. S., Zewdu, W. S., Ferede, Y. A., & Ewunetie, A. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105047 · Cited by 19
Mechanistic insights into the role of FOXO in diabetic retinopathy.
Behl, T., Wadhwa, M., Sehgal, A., Singh, S., Sharma, N., Bhatia, S., Al‐Harrasi, A., Aleya, L., & BUNGAU, S. G. (2022) · PubMed Central · Cited by 15
The Bidirectional Relationship of NPY and Mitochondria in Energy Balance Regulation
Sousa, D., Lopes, E., Silva, D., & Matafome, P. N. (2023) · Biomedicines · doi:10.3390/biomedicines11020446 · Cited by 19
Zhen, C., Li, J., Liu, J., Lyu, Y., Xie, L., & Lv, H. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166740 · Cited by 17
Platelet mitochondria, a potent immune mediator in neurological diseases
Ma, Y., Jiang, Q., Yang, B., Hu, X., Shen, G., Shen, W., & Xu, J. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1210509 · Cited by 18
Jeon, S., Jeong, P., Kim, M. J., Kang, H., Song, B., Kim, S., Cho, S., & Sim, B. (2023) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-023-00947-9 · Cited by 17
George, M., Reddy, A. P., Reddy, P. H., & Kshirsagar, S. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102353 · Cited by 19
Self-citationInferrera, F., Marino, Y., D’Amico, R., Impellizzeri, D., Cordaro, M., Siracusa, R., Gugliandolo, E., Fusco, R., Cuzzocrea, S., & Paola, R. D. (2024) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2024.110083 · Cited by 19
Emerging interactions between mitochondria and NAD+ metabolism in cardiometabolic diseases
Nasuhidehnavi, A., Zarzycka, W., Gorecki, I., Chiao, Y. A., & Lee, C. F. (2024) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2024.07.010 · Cited by 20
Hong, J. Y., Kim, H., Lee, J., Jeon, W., Baek, S. H., & Ha, I. (2021) · Antioxidants · doi:10.3390/antiox10030375 · Cited by 17
Rakhshandeh, H., Pourbagher‐Shahri, A. M., Hasanpour, M., Iranshahi, M., & Forouzanfar, F. (2022) · Metabolic Brain Disease · doi:10.1007/s11011-022-01094-2 · Cited by 17
Ye, Z., Wang, S., Wan, Z., Huang, B., & Guo, J. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1610429 · Cited by 16
Modulation of Nrf2 and Mitochondrial Function: Pharmacological Implications
Saso, L., Ateş, İ., Tunc, R., Yılmaz, B., Gallorini, M., Carradori, S., & Süzen, S. (2025) · Pharmaceuticals · doi:10.3390/ph18111698 · Cited by 18
Ni, F.-X., Hu, J., Chen, P.-S., Chen, H., Huang, D.-H., & Ze-Bo, J. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1714608 · Cited by 17
Heras, N. D. L., & Lahera, V. (2021) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-021-02638-8 · Cited by 19
Mitochondrial DNA Depletion Syndrome and Its Associated Cardiac Disease
Wang, H., Han, Y., Li, S., Chen, Y., Chen, Y., Wang, J., Zhang, Y., Zhang, Y., Wang, J., Xia, Y., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.808115 · Cited by 18
Development and Functions of Mitochondria in Early Life
Maheshwari, A., Peng, J., Ramatchandirin, B., Pearah, A., & He, L. (2022) · Newborn · doi:10.5005/jp-journals-11002-0013 · Cited by 17
Rizk, F. H., Soliman, N. A., Kashef, S. M., & Saadany, A. A. E. (2022) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-022-00925-1 · Cited by 19
Lee, H., An, G., Lim, W., & Song, G. (2022) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2022.105254 · Cited by 19
López‐Soldado, I., Torres, A. G., Ventura, R., Martínez-Ruíz, I., Díaz‐Ramos, A., Planet, E., Cooper, D., Pazderska, A., Wanic, K., O’Hanlon, D., et al. (2023) · Redox Biology · doi:10.1016/j.redox.2023.102630 · Cited by 16
Thủy, L. T. T., Lee, S., Dongquoc, V., & Choi, J. S. (2023) · Antioxidants · doi:10.3390/antiox12020437 · Cited by 16
Mitochondrial dysfunction in heart diseases: Potential therapeutic effects of Panax ginseng
Cao, X., Yao, F., Zhang, B., & Sun, X. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1218803 · Cited by 15
Sahadevan, R., Binoy, A., Shajan, I., & Sadhukhan, S. (2023) · RSC Advances · doi:10.1039/d3ra04527g · Cited by 16
Prasad, K., Sasi, S., Weerasinghe, J., Levchenko, I., & Bazaka, K. (2023) · Molecules · doi:10.3390/molecules28227481 · Cited by 19
Rojas-Solé, C., Pinilla-González, V., Lillo‐Moya, J., González-Fernández, T., Saso, L., & Rodrigo, R. (2023) · Redox Report · doi:10.1080/13510002.2023.2289740 · Cited by 21
Metadata
- Authors
- Bhatti, J. S., Bhatti, G. K., & Reddy, P. H.
- Affiliations
- Sri Guru Gobind Singh College (IN)
- Panjab University (IN)
- Texas Tech University (US)
- Corresponding author
- Bhatti, Jasvinder Singh
- Venue
- Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 1863
- Issue
- 5
- Pages
- 1066-1077
- ISSN
- 0925-4439 (ISSN-L)
- PMC
- PMC5423868
- OpenAlex
- W2553902009
- Cited by
- 1,655
- References
- 238
- Citations by year
- 2026: 168 · 2025: 319 · 2024: 293 · 2023: 235 · 2022: 246 · 2021: 151 · 2020: 115 · 2019: 65 · 2018: 34 · 2017: 29
- FWCI
- 3.86
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH (AG042178, AG047812)
- Garrison Family Foundation
- University Grants Commission, India (5-82/2016)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Keywords
- mitochondrial dysfunction, oxidative stress, metabolic syndrome, mitochondrial-targeted therapy, reactive oxygen species, apoptosis, caspases, diabetes mellitus, obesity, hypertension, stroke, heart disease, mitochondrial quality, lifestyle intervention, pharmacotherapy
- MeSH terms
- Animals, Humans, Metabolic Diseases, Mitochondria, Oxidative Stress
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
