Bile acids and glucocorticoid metabolism in health and disease

Identification of a nuclear receptor for bile acids

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Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor

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Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

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Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline

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An oxysterol signalling pathway mediated by the nuclear receptor LXRα

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβPreprint

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Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

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Endogenous Bile Acids Are Ligands for the Nuclear Receptor FXR/BAR

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A G Protein-coupled Receptor Responsive to Bile Acids

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Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα

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Activation of the Nuclear Receptor LXR by Oxysterols Defines a New Hormone Response Pathway

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Identification of a nuclear receptor that is activated by farnesol metabolites

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LXR, a nuclear receptor that defines a distinct retinoid response pathway.Preprint

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Regulation of the acute production of steroids in steroidogenic cells

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Corticosteroid insufficiency in acutely ill patients

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A 3-Level Prognostic Classification in Septic Shock Based on Cortisol Levels and Cortisol Response to Corticotropin

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Sterol-dependent Transactivation of theABC1 Promoter by the Liver X Receptor/Retinoid X Receptor

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Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of Critical Care Medicine

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A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism

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Regulation of ATP-binding Cassette Sterol Transporters ABCG5 and ABCG8 by the Liver X Receptors α and β

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Adrenal insufficiency

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LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

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Adrenal insufficiency

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Regulation of the acute production of steroids in steroidogenic cells

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Endocrine functions of bile acids

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Reduced Cortisol Metabolism during Critical Illness

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Adrenocorticotropin Stimulation Test: Effects of Basal Cortisol Level, Time of Day, and Suggested New Sensitive Low Dose Test*

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Circadian variation in basal plasma corticosterone and adrenocorticotropin in the rat: sexual dimorphism and changes across the estrous cycle

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Corticotropin tests for hypothalamic-pituitary- adrenal insufficiency: a metaanalysis

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Human White/Murine ABC8 mRNA Levels Are Highly Induced in Lipid-loaded Macrophages

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Diagnosis of Adrenal Insufficiency

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Characterization of CLA-1, a Human Homologue of Rodent Scavenger Receptor BI, as a Receptor for High Density Lipoprotein and Apoptotic Thymocytes

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A rapid test of adrenocortical function

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Clinical use of unbound plasma cortisol as calculated from total cortisol and corticosteroid-binding globulin

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Natural Structural Variants of the Nuclear Receptor Farnesoid X Receptor Affect Transcriptional Activation

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The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain

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Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency

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New therapeutic concepts in bile acid transport and signaling for management of cholestasis

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The clinical importance of adrenal insufficiency in acute hepatic dysfunction

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Cortisol Response in Relation to the Severity of Stress and Illness

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Mechanisms of Cholestasis

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The hepatoadrenal syndrome: A common yet unrecognized clinical condition*

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Measurement of salivary cortisol in 2012 – laboratory techniques and clinical indications

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Recent insights into organogenesis of the adrenal cortex

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Reproducibility of the circadian rhythms of serum cortisol and melatonin in healthy subjects: a study of three different 24-h cycles over six weeks

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Serum bile acids in liver disease

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FXR regulates organic solute transporters α and β in the adrenal gland, kidney, and intestine

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RE‐EVALUATION OF THE CLINICAL VALUE OF THE 30 MIN ACTH TEST IN ASSESSING THE HYPOTHALAMIC‐PITUITARY‐ADRENOCORTICAL FUNCTION

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Liver X receptors regulate adrenal cholesterol balance

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Adrenal cholesterol utilization

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Regulation of CYP3A4 by the bile acid receptor FXR

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Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimers

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SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance

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Mechanisms of disease: inborn errors of bile acid synthesis

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Minireview: Transcriptional Regulation of Adrenocortical Development

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Novel pathways of bile acid metabolism involving CYP3A4

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Factors influencing the adrenocorticotropin test: role of contemporary cortisol assays, body composition, and oral contraceptive agents

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Adrenarche in the rat

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Adrenocortical dysfunction in liver disease: A systematic review

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Assessment of adrenal function in cirrhotic patients: salivary cortisol should be preferred.

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The Effect of Hypotension in Obstructive Jaundice

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Role of glucocorticoids and the glucocorticoid receptor in metabolism: Insights from genetic manipulations

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Potential Reversibility of Rheumatoid Arthritis

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Characterising adrenal function using directly measured plasma free cortisol in stable severe liver disease.

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The Effects of Proopiomelanocortin Deficiency on Murine Adrenal Development and Responsiveness to Adrenocorticotropin

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MOLECULAR EVOLUTION OF GPCRS: Melanocortin/melanocortin receptors

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Absence of HDL cholesteryl ester uptake in mice via SR-BI impairs an adequate adrenal glucocorticoid-mediated stress response to fasting

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Bile acids modulate glucocorticoid metabolism and the hypothalamic–pituitary–adrenal axis in obstructive jaundice

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Adrenal-exhaustion syndrome in patients with liver disease

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Immediate neuroendocrine signaling after partial hepatectomy through acute portal hyperpressure and cholestasis

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The melanocortin receptors and their accessory proteins

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Advantage of salivary cortisol measurements in the diagnosis of glucocorticoid related disorders

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Adrenal Function in Heterozygous and Homozygous Hypobetalipoproteinemia*

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Suppression of the HPA axis during cholestasis can be attributed to hypothalamic bile acid signaling

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Is a 0900-h serum cortisol useful prior to a short Synacthen test in outpatient assessment?

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Impact of Duration of Critical Illness on the Adrenal Glands of Human Intensive Care Patients

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The heteromeric organic solute transporter, OSTα–OSTβ/SLC51: A transporter for steroid-derived molecules

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High density lipoprotein in patients with liver failure; relation to sepsis, adrenal function and outcome of illness

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Melanocortin receptors and their accessory proteins

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Circulating bile acids predict outcome in critically ill patients

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