Regulation of the acute production of steroids in steroidogenic cells
Abstract
The steroid hormones constitute a very important class of compounds and are present in most species. The hormones that are synthesized in the adrenal gland, namely the glucocorticoids and the mineralocorticoids, are important for the maintenance of carbohydrate metabolism, stress management, and salt balance. The “male” sex steroids, the androgens, which are responsible for the maintenance of reproductive function and secondary sex characteristics, are also an important member of this family and are synthesized in the testis. Lastly, the “female” sex steroids, the progestins and estrogens, are synthesized in the ovary and the placenta and function to induce secondary sex characteristics and are also essential for reproduction. An additional class of steroids, known as the neuroactive or neural steroids, are synthesized by the central nervous system (CNS) and appear to have specialized functions in this tissue. While neural steroids constitute an extremely interesting class of compounds, they will not be considered further in this review. Thus, the steroid hormones can be distinguished by their diverse physiological actions in the body. However, regardless of the tissue of origin, the steroid hormones are all synthesized from a common substrate, cholesterol; therefore, they are all structurally similar. The biosynthesis of all hormonal steroids in response to trophic hormone and other steroidogenic stimuli begins with the enzymatic cleavage of the side chain of cholesterol to form the first steroid synthesized in all steroidogenic tissues, pregnenolone.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
P450scc (CYP11A1) plays an essential role converting cholesterol to pregnenolone.
“The cholesterol side-chain cleavage enzyme, P450scc (CYP11A1), plays an essential role converting cholesterol to pregnenolone.”
From Congenital lipoid adrenal hyperplasia (2014) · cites this paper as [5]
BAs might act via TGR5 in a cAMP/PKA-dependent fashion to phosphorylate and activate StAR and HSL.
“BAs might act via TGR5 in a cAMP/protein kinase A (PKA)-dependent fashion phosphorylating and thus activating steroidogenic acute regulatory protein (StAR) and hormone sensitive lipase (HSL) (316).”
From Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis (2023) · cites this paper as [316]
Cites
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719 · see citing works
The Physiology of Reproduction
Legendre, M., & Jalabert, B. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-2-176_1 · Cited by 7,879 · see citing works
PROTEIN SERINE/THREONINE KINASES
Edelman, A. M., Blumenthal, D., & Krebs, E. G. (1987) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.56.070187.003031 · Cited by 1,435 · see citing works
Molecular biology of steroid hormone synthesis
MILLER, W. L. (1988) · Endocrine Reviews · doi:10.1210/edrv-9-3-295 · Cited by 1,397 · see citing works
PROTEIN IMPORT INTO MITOCHONDRIA
Neupert, W. (1997) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.66.1.863 · Cited by 1,060 · see citing works
Hormonal Regulation of the Differentiation of Cultured Ovarian Granulosa Cells*
Hsueh, A. J. W., Adashi, E. Y., JONES, P. B. C., & Welsh, T. H. (1984) · Endocrine Reviews · doi:10.1210/edrv-5-1-76 · Cited by 1,010 · see citing works
McEnery, M. W., Snowman, A. M., Trifiletti, R. R., & Snyder, S. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.8.3170 · Cited by 708 · see citing works
The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane.
Anholt, R. R. H., Pedersen, P. L., Souza, E. B. D., & Snyder, S. H. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36131-8 · Cited by 696 · see citing works
Ascoli, M. (1981) · Endocrinology · doi:10.1210/endo-108-1-88 · Cited by 582 · see citing works
Steroidogenic enzymes: Structure, function, and role in regulation of steroid hormone biosynthesis
Hanukoglu, I. (1992) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(92)90307-5 · Cited by 551 · see citing works
Mechanisms and consequences of cellular cholesterol exchange and transfer
Phillips, M. C., Johnson, W. J., & Rothblat, G. H. (1987) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(87)90013-x · Cited by 541 · see citing works
Mitochondrial contact sites. Lipid composition and dynamics.
Ardail, D., Privat, J., Egret-Charlier, M., Levrat, C., Lermé, F., & Louisot, P. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)30583-5 · Cited by 445 · see citing works
Stone, D. A., & Hechter, O. (1954) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(54)90501-9 · Cited by 445 · see citing works
PAPADOPOULOS, V. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-2-222 · Cited by 417 · see citing works
Garren, L. D., Ney, R. L., & Davis, W. W. (1965) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.53.6.1443 · Cited by 388 · see citing works
The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis
Papadopoulos, V, Mukhin, A. G., Costa, E., & Krueger, K. E. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39661-9 · Cited by 346 · see citing works
Krueger, K. E., & Papadopoulos, V. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)77217-7 · Cited by 345 · see citing works
Protein Synthesis and Adrenocorticotropin Responsiveness
Ferguson, J. J. (1963) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67893-7 · Cited by 343 · see citing works
Privalle, C. T., Crivello, J. F., & Jefcoate, C. R. E. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.3.702 · Cited by 338 · see citing works
Diazepam binding inhibitor (DBI): A peptide with multiple biological actions
Costa, E., & Guidotti, A. (1991) · Life Sciences · doi:10.1016/0024-3205(91)90440-m · Cited by 307 · see citing works
Peripheral Type Benzodiazepine Receptors
Verma, A. M., & Snyder, S. H. (1989) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.29.040189.001515 · Cited by 286 · see citing works
On the Mechanism of Action of ACTH
Garren, L. D., Gill, G. N., Masui, H., & Walton, G. M. (1971) · Elsevier eBooks · doi:10.1016/b978-0-12-571127-2.50035-3 · Cited by 260 · see citing works
Membrane Cholesterol Dynamics: Cholesterol Domains and Kinetic Pools
Schroeder, F., Jefferson, J. R., Kier, A. B., Knittel, J. J., Scallen, T. J., Wood, W. G., & Hapala, I. (1991) · Experimental Biology and Medicine · doi:10.3181/00379727-196-43185 · Cited by 257 · see citing works
Mitochondrial benzodiazepine receptors regulate steroid biosynthesis.
Mukhin, A. G., Papadopoulos, V., Costa, E., & Krueger, K. E. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.24.9813 · Cited by 256 · see citing works
Stocco, D. M., & Sodeman, T. C. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55053-5 · Cited by 249 · see citing works
Self-citationEpstein, L. F., & Orme-Johnson, N. R. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55054-7 · Cited by 247 · see citing works
Karaboyas, G. C., & Koritz, S. B. (1965) · Biochemistry · doi:10.1021/bi00879a014 · Cited by 247 · see citing works
Hartwig, W. (1984) · PubMed · Cited by 247 · see citing works
Besman, M. J., Yanagibashi, K., Lee, T. D., Kawamura, M., Hall, P. F., & Shively, J. E. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.13.4897 · Cited by 240 · see citing works
Intracellular movement of cholesterol in rat adrenal cells. Kinetics and effects of inhibitors
Crivello, J. F., & Jefcoate, C. R. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)70620-6 · Cited by 230 · see citing works
Chanderbhan, R. F., Noland, B. J., Scallen, T. J., & Vahouny, G. V. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34222-4 · Cited by 229 · see citing works
Papadopoulos, V., Guarneri, P., Kreuger, K. E., Guidotti, A., & Costa, E. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.11.5113 · Cited by 224 · see citing works
Characterization of translocation contact sites involved in the import of mitochondrial proteins.
Schwaiger, M., Herzog, V., & Neupert, W. (1987) · The Journal of Cell Biology · doi:10.1083/jcb.105.1.235 · Cited by 220 · see citing works
Simpson, E. R., McCarthy, J., & Peterson, J. A. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40813-1 · Cited by 215 · see citing works
Rassow, J., Guiard, B., Wienhues, U., Herzog, V., Hartl, F. U., & Neupert, W. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.109.4.1421 · Cited by 209 · see citing works
Papadopoulos, V., Berkovich, A., Krueger, K. E., Costa, E., & Guidotti, A. (1991) · Endocrinology · doi:10.1210/endo-129-3-1481 · Cited by 207 · see citing works
Kinnally, K. W., Zorov, D. B., Antonenko, Y. N., Snyder, S. H., McEnery, M. W., & Tedeschi, H. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.4.1374 · Cited by 205 · see citing works
Acute ACTH regulation of adrenal corticosteroid biosynthesis: rapid accumulation of a phosphoprotein
Pon, L. A., Hartigan, J. A., & Orme-Johnson, N. R. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69305-6 · Cited by 200 · see citing works
Intracellular cholesterol transport.
Liscum, L., & Dahl, N. (1992) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40539-5 · Cited by 195 · see citing works
Keller, G. A., Scallen, T. J., Clarke, D., Maher, P. A., Krisans, S. K., & Singer, S. J. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.108.4.1353 · Cited by 190 · see citing works
Regulation by ACTH of steroid hormone biosynthesis in the adrenal cortex
Simpson, E. R., & Waterman, M. R. (1983) · Canadian Journal of Biochemistry and Cell Biology · doi:10.1139/o83-088 · Cited by 189 · see citing works
Krueger, R. J., & ORME-JOHNSON, N. R. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44619-9 · Cited by 184 · see citing works
Regulation of cholesterol movement to mitochondrial cytochrome P450scc in steroid hormone synthesis
Jefcoate, C. R. E., McNamara, B. C., Artemenko, I. P., & Yamazaki, T. (1992) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(92)90305-3 · Cited by 184 · see citing works
Sala, G. B. L., Hayashi, K., Catt, K. J., & Dufau, M. L. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50666-9 · Cited by 177 · see citing works
Pon, L. A., Moll, T., Vestweber, D., Marshallsay, B., & Schatz, G. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.109.6.2603 · Cited by 166 · see citing works
Lambeth, J. D., Seybert, D. W., & Kamin, H. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50312-4 · Cited by 165 · see citing works
Detection of Trace Molecular Species Using Degenerate Four-Wave Mixing
Farrow, R. L., & Rakestraw, D. J. (1992) · Science · doi:10.1126/science.257.5078.1894 · Cited by 165 · see citing works
Snyder, S. H., Verma, A. M., & Trifiletti, R. R. (1987) · The FASEB Journal · doi:10.1096/fasebj.1.4.2820823 · Cited by 158 · see citing works
Pon, L. A., & Orme-Johnson, N. R. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)84604-5 · Cited by 151 · see citing works
Garnier, M. J., Boujrad, N., Oke, B. O., Brown, A., Riond, J., Ferrara, P., SHOYAB, M., Suarez‐Quian, C. A., & Papadopoulos, V. (1993) · Endocrinology · doi:10.1210/endo.132.1.8380386 · Cited by 146 · see citing works
Vahouny, G. V., Chanderbhan, R. F., Noland, B. J., Irwin, D. J., Dennis, P., Lambeth, J. D., & Scallen, T. J. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44290-6 · Cited by 143 · see citing works
Vestweber, D., & Schatz, G. (1988) · The Journal of Cell Biology · doi:10.1083/jcb.107.6.2037 · Cited by 142 · see citing works
The role of microfilaments in the response of adrenal tumor cells to adrenocorticotropic hormone.
Hall, P. F., Charponnier, C., Nakamura, M., & Gabbiani, G. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86812-6 · Cited by 135 · see citing works
Steroidogenesis-Activator Polypeptide Isolated from a Rat Leydig Cell Tumor
Pedersen, R. C., & Brownie, A. C. (1987) · Science · doi:10.1126/science.3563495 · Cited by 135 · see citing works
Pedersen, R. C., & Brownie, A. C. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.7.1882 · Cited by 132 · see citing works
Cellular Organization for Steroidogenesis
Hall, P. F. (1984) · International review of cytology · doi:10.1016/s0074-7696(08)60177-1 · Cited by 131 · see citing works
Crivello, J. F., & Jefcoate, C. R. E. (1978) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(78)90027-2 · Cited by 124 · see citing works
Ohlendieck, K., Riesinger, I., Adams, V., Krause, J., & Brdiczka, D. G. (1986) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(86)90567-5 · Cited by 117 · see citing works
Yanagibashi, K., Ohno, Y., Kawamura, M., & Hall, P. F. (1988) · Endocrinology · doi:10.1210/endo-123-4-2075 · Cited by 116 · see citing works
Mitochondrial Benzodiazepine Receptors and the Regulation of Steroid Biosynthesis
Krueger, K. E., & Papadopoulos, V. (1992) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.32.040192.001235 · Cited by 115 · see citing works
Yanagibashi, K., Ohno, Y., Nakamichi, N., Matsui, T., Hayashida, K., Takamura, M., Yamada, K., Shohei, T. O. U., & Kawamura, M. (1989) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a122958 · Cited by 114 · see citing works
Cloning and expression of a cDNA encoding human sterol carrier protein 2.
Yamamoto, R., Kallen, C. B., Babalola, G. O., Rennert, H. S., Billheimer, J. T., & Strauss, J. F. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.2.463 · Cited by 114 · see citing works
Response of adrenal tumor cells to adrenocorticotropin: site of inhibition by cytochalasin B
Mrotek, J. J., & Hall, P. F. (1977) · Biochemistry · doi:10.1021/bi00633a021 · Cited by 113 · see citing works
Papadopoulos, V., Nowzari, F. B., & Krueger, K. E. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)67848-8 · Cited by 111 · see citing works
ACTH regulation of cholesterol movement in isolated adrenal cells
Jefcoate, C. R. E., Dibartolomeis, M. J., Williams, C. A., & McNamara, B. C. (1987) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(87)90142-7 · Cited by 108 · see citing works
The role of cyclic AMP in gonadal function.
Marsh, J. M. (1975) · PubMed · Cited by 107 · see citing works
Hwang, S. T., Wachter, C., & Schatz, G. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54823-7 · Cited by 106 · see citing works
Stocco, D. M., & Chen, W. (1991) · Endocrinology · doi:10.1210/endo-128-4-1918 · Cited by 103 · see citing works
Self-citationAlberta, J. A., Epstein, L. F., Pon, L. A., & ORME-JOHNSON, N. R. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)94186-4 · Cited by 99 · see citing works
Induction of mitochondrial proteins in MA-10 Leydig tumour cells with human choriogonadotropin
Stocco, D. M., & Kilgore, M. W. (1988) · Biochemical Journal · doi:10.1042/bj2490095 · Cited by 99 · see citing works
Self-citationThe effects of hydrogen peroxide on steroidogenesis in mouse Leydig tumor cells.
Stocco, D. M., Wells, J. O., & Clark, B. J. (1993) · Endocrinology · doi:10.1210/endo.133.6.8243310 · Cited by 95 · see citing works
Self-citationHanukoglu, I., & HANUKOGLU, Z. (1986) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1986.tb09633.x · Cited by 94 · see citing works
van Amerongen, A., DEMEL, R. A., Westerman, J., & WIRTZ, K. W. A. (1989) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(89)90209-9 · Cited by 90 · see citing works
Sterol Carrier and Lipid Transfer Proteins
Vahouny, G. V., Chanderbhan, R. F., Kharroubi, A., Noland, B. J., Pastuszyn, A., & Scallen, T. J. (1987) · Advances in lipid research · doi:10.1016/b978-0-12-024922-0.50007-2 · Cited by 90 · see citing works
Cell surface localization of the peripheral-type benzodiazepine receptor (PBR) in adrenal cortex
Oke, B. O., Suarez‐Quian, C. A., Riond, J., Ferrara, P., & Papadopoulos, V. (1992) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(92)90248-5 · Cited by 87 · see citing works
COOKE, B. A., Lindh, M. L., & Janszen, F. H. A. (1976) · Biochemical Journal · doi:10.1042/bj1600439 · Cited by 87 · see citing works
Trzeciak, W. H., Simpson, E. R., Scallen, T. J., Vahouny, G. V., & Waterman, M. R. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)61413-9 · Cited by 86 · see citing works
Distinctive properties of adrenal cortex mitochondria
ORME-JOHNSON, N. R. (1990) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(90)90151-s · Cited by 85 · see citing works
Mendelson, C. R., Dufau, M. L., & Catt, K. J. (1975) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(75)90302-5 · Cited by 81 · see citing works
Regulation of pregnenolone synthesis in C6-2B glioma cells by 4'-chlorodiazepam.
Guarneri, P., Papadopoulos, V., Pan, B., & Costa, E. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.11.5118 · Cited by 80 · see citing works
Electrophysiological characterization of contact sites in brain mitochondria.
Morán, Ó., Sandri, G., Panfili, E., et al. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)40136-1 · Cited by 78 · see citing works
Intracellular sterol trafficking
Reinhart, M. P. (1990) · Cellular and Molecular Life Sciences · doi:10.1007/bf01939699 · Cited by 78 · see citing works
Boujrad, N., Hudson, J. R., & Papadopoulos, V. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.12.5728 · Cited by 77 · see citing works
Arthur, J. R., & Boyd, G. S. (1974) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1974.tb03817.x · Cited by 77 · see citing works
Lambeth, J. D., Xu, X. X., & Glover, M. R. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48065-9 · Cited by 75 · see citing works
Pon, L. A., Epstein, L. F., & ORME-JOHNSON, N. R. (1986) · Endocrine Research · doi:10.3109/07435808609035449 · Cited by 74 · see citing works
Pon, L. A., & ORME-JOHNSON, N. R. (1988) · Endocrinology · doi:10.1210/endo-123-4-1942 · Cited by 71 · see citing works
Privalle, C. T., McNamara, B. C., Dhariwal, M. S., & Jefcoate, C. R. E. (1987) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(87)90195-x · Cited by 70 · see citing works
Amsterdam, A., & Suh, B. S. (1991) · Endocrinology · doi:10.1210/endo-129-1-503 · Cited by 70 · see citing works
Nagy, L., & Freeman, D. A. (1990) · Endocrinology · doi:10.1210/endo-126-5-2267 · Cited by 68 · see citing works
Attachment of steroidogenic lipid droplets to intermediate filaments in adrenal cells
Almahbobi, G., Williams, L. J., & Hall, P. F. (1992) · Journal of Cell Science · doi:10.1242/jcs.101.2.383 · Cited by 67 · see citing works
Elliott, M. E., Goodfriend, T. L., & Jefcoate, C. R. E. (1993) · Endocrinology · doi:10.1210/endo.133.4.8404608 · Cited by 64 · see citing works
Epstein, L. F., & ORME-JOHNSON, N. R. (1991) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(91)90210-j · Cited by 63 · see citing works
van Amerongen, A., van Noort, M., van Beckhoven, J. R. C. M., et al. (1989) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(89)90106-9 · Cited by 63 · see citing works
Modulatory action of benzodiazepines on human term placental steroidogenesis in vitro
Barnea, E. R., Fares, F., & Gavish, M. (1989) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(89)90141-x · Cited by 60 · see citing works
Stocco, D. M., & Ascoli, M. (1993) · Endocrinology · doi:10.1210/endo.132.3.8382603 · Cited by 58 · see citing works
Self-citationFreeman, D. A. (1989) · Endocrinology · doi:10.1210/endo-124-5-2527 · Cited by 58 · see citing works
Cavallaro, S., Korneyev, A., Guidotti, A., & Costa, E. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.22.10598 · Cited by 57 · see citing works
Stocco, D. M., & Clark, B. J. (1993) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(93)90223-j · Cited by 57 · see citing works
Self-citationPapadopoulos, V., Berkovich, A., & Krueger, K. E. (1991) · Neuropharmacology · doi:10.1016/s0028-3908(11)80011-0 · Cited by 56 · see citing works
The role of the cytoskeleton in hormone action
Hall, P. F. (1984) · Canadian Journal of Biochemistry and Cell Biology · doi:10.1139/o84-087 · Cited by 55 · see citing works
Sterol Carrier Protein2: Further Evidence for Its Role in Adrenal Steroidogenesis
Chanderbhan, R. F., Kharroubi, A., Noland, B. J., Scallen, T. J., & Vahouny, G. V. (1986) · Endocrine Research · doi:10.3109/07435808609035445 · Cited by 55 · see citing works
The role of cyclic AMP in the regulation of steroid biosynthesis in testis tissue
ROMMERTS, F. F. G., COOKE, B. A., & van der Molen, H. J. (1974) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(74)90143-5 · Cited by 54 · see citing works
Binding of lipid droplets and mitochondria to intermediate filaments in rat Leydig cells
Almahbobi, G., Williams, L. J., Han, X.-G., et al. (1993) · Reproduction · doi:10.1530/jrf.0.0980209 · Cited by 53 · see citing works
Soto, E. A. (1986) · Biology of Reproduction · doi:10.1095/biolreprod34.3.559 · Cited by 53 · see citing works
Tuls, J. L., Geren, L., Lambeth, J. D., & Millett, F. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)61068-3 · Cited by 52 · see citing works
Schulster, D., Richardson, M. C., & Palfreyman, J. W. (1974) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(74)90009-4 · Cited by 50 · see citing works
The role of intermediate filaments in adrenal steroidogenesis
Almahbobi, G., & Hall, P. F. (1990) · Journal of Cell Science · doi:10.1242/jcs.97.4.679 · Cited by 50 · see citing works
Brown, A., Hall, P. F., SHOYAB, M., & Papadopoulos, V. (1992) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(92)90189-d · Cited by 48 · see citing works
Python, C. P., Rossier, M. F., Vallotton, M. B., & Capponi, A. M. (1993) · Endocrinology · doi:10.1210/endo.132.4.8384990 · Cited by 48 · see citing works
Almahbobi, G., Williams, L. J., & Hall, P. F. (1992) · Experimental Cell Research · doi:10.1016/0014-4827(92)90184-a · Cited by 46 · see citing works
Fujiki, Y., Tsuneoka, M., & Tashiro, Y. (1989) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a122977 · Cited by 45 · see citing works
The kinetics of steroidogenesis activator polypeptide in the rat adrenal cortex
Mertz, L. M., & Pedersen, R. C. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)84821-4 · Cited by 44 · see citing works
Stocco, D. M. (1992) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(92)90167-h · Cited by 44 · see citing works
Self-citationRNA synthesis and adrenocorticotropin responsiveness
Ferguson, J. J., & Morita, Y. (1964) · Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects · doi:10.1016/0926-6550(64)90234-8 · Cited by 44 · see citing works
Hormone-stimulated Steroidogenesis Is Coupled to Mitochondrial Benzodiazepine Receptors
PapadopoulosS, V., Nowzari, F. B., & Krueger, K. E. (1991) · Cited by 44 · see citing works
Chaudhary, L. R., & Stocco, D. M. (1991) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/0167-4889(91)90006-j · Cited by 40 · see citing works
Self-citationTranslocation arrest by reversible folding of a precursor protein imported into mitochondria
Rassow, J., Guiard, B., Wienhues, U., et al. (1989) · Open access LMU (Ludwid Maxmilian's Universitat Munchen) · Cited by 40 · see citing works
The role of the cytoskeleton in the regulation of steroidogenesis
Hall, P. F., & Almahbobi, G. (1992) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(92)90306-4 · Cited by 39 · see citing works
Evidence for the functional coupling of cyclic AMP in MA-10 mouse Leydig tumour cells
Stocco, D. M., & Chaudhary, L. R. (1990) · Cellular Signalling · doi:10.1016/0898-6568(90)90019-7 · Cited by 38 · see citing works
Self-citationStudies on Peroxisomes of the Adult Rat Leydig Cell
Mendis-Handagama, S. M. L. C., Zirkin, B. R., Scallen, T. J., et al. (1990) · Journal of Andrology · doi:10.1002/j.1939-4640.1990.tb03239.x · Cited by 37 · see citing works
Heterogeneity of Template RNA in Adrenal Glands
Ney, R. L., Davis, W. W., & Garren, L. D. (1966) · Science · doi:10.1126/science.153.3738.896 · Cited by 37 · see citing works
Cholesterol Ester Hydrolase and Sterol Carrier Proteins
Vahouny, G. V., Chanderbhan, R. F., Noland, B. J., et al. (1984) · Endocrine Research · doi:10.1080/07435808409036512 · Cited by 37 · see citing works
Contact sites between inner and outer membranes
Pfanner, N., Rassow, J., Wienhues, U., Hergersberg, C., Söllner, T. H., Becker, K., & Neupert, W. (1990) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(90)90257-5 · Cited by 37 · see citing works
Li, X., Warren, D. W., Gregoire, J., Pedersen, R. C., & Lee, A. S. (1989) · Molecular Endocrinology · doi:10.1210/mend-3-12-1944 · Cited by 33 · see citing works
Sandri, G., Siagri, M., & Panfili, E. (1988) · Cell Calcium · doi:10.1016/0143-4160(88)90020-6 · Cited by 32 · see citing works
Diazepam-binding inhibitor: a neuropeptide and/or an acyl-CoA ester binding protein?
Knudsen, J., & Nielsen, M. B. (1990) · Biochemical Journal · doi:10.1042/bj2650927 · Cited by 32 · see citing works
Polypeptide Activators of Cholesterol Side-Chain Cleavage
Pedersen, R. C. (1984) · Endocrine Research · doi:10.1080/07435808409036515 · Cited by 31 · see citing works
Nagy, L., & Freeman, D. A. (1990) · Biochemical Journal · doi:10.1042/bj2710809 · Cited by 31 · see citing works
Stimulation by endozepine of the side-chain cleavage of cholesterol in a reconstituted enzyme system
Brown, A., & Hall, P. F. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(05)81109-x · Cited by 30 · see citing works
Cholesterol trafficking in steroidogenic cells
Stevens, V. L., Xu, T., & Lambeth, J. D. (1993) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1993.tb18174.x · Cited by 29 · see citing works
Diazepam inhibits potassium-induced aldosterone secretion in adrenal glomerulosa cell
Shibata, H., Kojima, I., & Ogata, E. (1986) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(86)91026-0 · Cited by 29 · see citing works
Steroidogenesis activator polypeptide (SAP) in the rat ovary and testi
Pedersen, R. C. (1987) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(87)90143-9 · Cited by 28 · see citing works
Krueger, R. J., & ORME-JOHNSON, N. R. (1988) · Endocrinology · doi:10.1210/endo-122-5-1869 · Cited by 26 · see citing works
van Noort, M., ROMMERTS, F. F. G., van Amerongen, A., & WIRTZ, K. W. A. (1988) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(88)90017-2 · Cited by 25 · see citing works
Evidence for the involvement of lutropin-independent RNA synthesis in Leydig cell steroidogenesis
COOKE, B. A., Janszen, F. H. A., Driel, M. J. A. V., et al. (1979) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(79)90043-1 · Cited by 23 · see citing works
On the role of protein synthesis in the response of adrenal tumor cells to ACTH
Nakamura, M., Watanuki, M., & Hall, P. F. (1978) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(78)90115-6 · Cited by 22 · see citing works
Holloway, C. D., Kenyon, C. J., Dowie, L. J., Corrie, J. E. T., GRAY, C. E., & Fraser, R. (1989) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(89)90297-5 · Cited by 22 · see citing works
Subcellular Localization of a Protein Produced in Adrenal Cortex Cells in Response to Acth
Epstein, L. F., Alberta, J. A., Pon, L. A., & ORME-JOHNSON, N. R. (1989) · Endocrine Research · doi:10.1080/07435808909039092 · Cited by 22 · see citing works
Inhibition of steroidogenesis in rat adrenal cortex cells by a threonine analogue
Green, E. G., & ORME-JOHNSON, N. R. (1991) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(91)90211-m · Cited by 21 · see citing works
Steroidogenesis activator polypeptide (SAP) in the guinea pig adrenal cortex
Frustaci, J. M., Mertz, L. M., & Pedersen, R. C. (1989) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(89)90139-1 · Cited by 20 · see citing works
Corticosteroid and ribonucleic acid synthesis in isolated adrenal cells: Inhibition by actinomycin D
Schulster, D. (1974) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(74)90038-0 · Cited by 20 · see citing works
Steroidogenesis Activator Polypeptide May be a Product of Glucose Regulated Protein 78 (GRP78)
Mertz, L. M., & Pedersen, R. C. (1989) · Endocrine Research · doi:10.1080/07435808909039091 · Cited by 18 · see citing works
Cavallaro, S., Pani, L., Guidotti, A., & Costa, E. (1993) · Life Sciences · doi:10.1016/0024-3205(93)90550-m · Cited by 17 · see citing works
Thomson, I., Fräser, R., & Kenyon, C. J. (1992) · Journal of Endocrinology · doi:10.1677/joe.0.1350361 · Cited by 14 · see citing works
Calvo, D. J., Ritta, M. N., Calandra, R. S., & Medina, J. H. (2008) · Neuroendocrinology · doi:10.1159/000125606 · Cited by 11 · see citing works
Acute stimulation by lutropin of mitochondrial protein synthesis in small luteal cells
Mittre, H., Aunai, P., Benhaïm, A., & Leymarie, P. (1990) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1990.tb15359.x · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
Miller, W. L., & Auchus, R. J. (2011) · Endocrine Reviews · doi:10.1210/er.2010-0013 · Cited by 2,458 · see citing works
StAR protein and the regulation of steroid hormone biosynthesis.
Stocco, D. M. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.193 · Cited by 917 · see citing works
Self-citationNeurosteroids: biosynthesis and function of these novel neuromodulators
Compagnone, N. A., & Mellon, S. H. (2000) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1999.0188 · Cited by 820 · see citing works
Stocco, D. M., Wang, X., Jo, Y., & Manna, P. R. (2005) · Molecular Endocrinology · doi:10.1210/me.2004-0532 · Cited by 538 · see citing works
Self-citationControl and biochemical nature of the ecdysteroidogenic pathway
Gilbert, L. I., Rybczynski, R., & Warren, J. T. (2002) · Annual Review of Entomology · doi:10.1146/annurev.ento.47.091201.145302 · Cited by 532 · see citing works
Enigma of the peripheral benzodiazepine receptor
Gavish, M., Bachman, I., Shoukrun, R., Katz, Y., Veenman, L., Weisinger, G., & Weizman, A. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01424-8 · Cited by 512 · see citing works
Control of aldosterone secretion: a model for convergence in cellular signaling pathways
SPÄT, A., & HUNYADY, L. (2004) · Physiological Reviews · doi:10.1152/physrev.00030.2003 · Cited by 494 · see citing works
Caron, K. M., Soo, S.-C., Wetsel, W. C., Stocco, D. M., Clark, B. J., & Parker, K. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11540 · Cited by 449 · see citing works
Self-citationDNA binding and transcriptional repression by DAX-1 blocks steroidogenesis
Zazopoulos, E., Lalli, E., Stocco, D. M., & Sassone-Corsi, P. (1997) · Nature · doi:10.1038/36899 · Cited by 433 · see citing works
Self-citationSignalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis
Rusch, J. A., Layden, B. T., & Dugas, L. R. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1130689 · Cited by 415 · see citing works
Arakane, F., King, S. R., Du, Y., Kallen, C. B., Walsh, L. P., Watari, H., Stocco, D. M., & Strauss, J. F. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.51.32656 · Cited by 391 · see citing works
Self-citationSteroidogenesis in the skin: Implications for local immune functions
Slominski, A., Zbytek, B., Nikolakis, G., Manna, P. R., Skobowiat, C., Zmijewski, M., Li, W., Janjetovic, Z., Postlethwaite, A., Zouboulis, C. C., et al. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.02.006 · Cited by 369 · see citing works
Rapid regulation of steroidogenesis by mitochondrial protein import
Bose, H. S., Lingappa, V. R., & Miller, W. L. (2002) · Nature · doi:10.1038/417087a · Cited by 357 · see citing works
Lacapère, J.-J., & Papadopoulos, V. (2003) · Steroids · doi:10.1016/s0039-128x(03)00101-6 · Cited by 342 · see citing works
Sherlock, M., Scarsbrook, A., Abbas, A., Fraser, S., Limumpornpetch, P., Dineen, R., & Stewart, P. M. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa008 · Cited by 347 · see citing works
“Glucocorticoids are secreted in relatively high amounts (cortisol 10-20 mg/day) from the zona fasciculata cells under the control of ACTH secreted from the anterior pituitary (92).”
BackgroundInfluentialMinireview: Regulation of Steroidogenesis by Electron Transfer
Miller, W. L. (2005) · Endocrinology · doi:10.1210/en.2005-0096 · Cited by 324 · see citing works
Arakane, F., Sugawara, T., Nishino, H., Liu, Z., Holt, J. A., Pain, D., Stocco, D. M., Miller, W. L., & Strauss, J. F. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.13731 · Cited by 304 · see citing works
Self-citationSpiga, F., Walker, J. J., Terry, J. R., & Lightman, S. L. (2014) · Comprehensive Physiology · doi:10.1002/cphy.c140003 · Cited by 267 · see citing works
Transcriptional regulation of steroidogenic genes: StARD1, CYP11A1 and HSD3B
LaVoie, H. A., & King, S. R. (2009) · Experimental Biology and Medicine · doi:10.3181/0903-mr-97 · Cited by 261 · see citing works
Hauet, T., Yao, Z.-X., Bose, H. S., Wall, C. T., Han, Z., Li, W., Hales, D. B., Miller, W. L., Culty, M., & Papadopoulos, V. (2005) · Molecular Endocrinology · doi:10.1210/me.2004-0307 · Cited by 252 · see citing works
Watari, H., Arakane, F., Moog-Lutz, C., Kallen, C. B., Tomasetto, C., Gerton, G. L., Rio, M.-C., Baker, M. E., & Strauss, J. F. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.16.8462 · Cited by 247 · see citing works
Caron, K. M., Ikeda, Y., Soo, S.-C., Stocco, D. M., Parker, K. L., & Clark, B. J. (1997) · Molecular Endocrinology · doi:10.1210/mend.11.2.9880 · Cited by 243 · see citing works
Self-citationThe active form of the steroidogenic acute regulatory protein, StAR, appears to be a molten globule
Bose, H. S., Whittal, R. M., Baldwin, M. A., & Miller, W. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.13.7250 · Cited by 227 · see citing works
Manna, P. R., Dyson, M. T., Eubank, D. W., Clark, B. J., Lalli, E., Sassone-Corsi, P., Zeleznik, A. J., & Stocco, D. M. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.1.0759 · Cited by 232 · see citing works
Self-citation11-Oxygenated androgens in health and disease
Turcu, A. F., Rege, J., Auchus, R. J., & Rainey, W. E. (2020) · Nature Reviews Endocrinology · doi:10.1038/s41574-020-0336-x · Cited by 217 · see citing works
Disorders in the initial steps of steroid hormone synthesis
Miller, W. L. (2017) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2016.03.009 · Cited by 205 · see citing works
Tajima, T., Fujieda, K., Kouda, N., Nakae, J., & Miller, W. L. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.8.7748 · Cited by 196 · see citing works
Baker, B. Y., Lin, L., Kim, C. J., Raza, J., Smith, C. P., Miller, W. L., & Achermann, J. C. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1565 · Cited by 194 · see citing works
Azhar, S., & Reaven, E. (2002) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(02)00222-8 · Cited by 192 · see citing works
Nakae, J. (1997) · Human Molecular Genetics · doi:10.1093/hmg/6.4.571 · Cited by 188 · see citing works
The origin of glucocorticoid hormone oscillations
Walker, J. J., Spiga, F., Waite, E., Zhao, Z., Kershaw, Y., Terry, J. R., & Lightman, S. L. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001341 · Cited by 189 · see citing works
Miller, W. L., & Strauss, J. F. (1999) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(98)00153-8 · Cited by 184 · see citing works
Androgen biosynthesis from cholesterol to DHEA
Miller, W. L. (2002) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(02)00363-5 · Cited by 179 · see citing works
Cherradi, N., Rossier, M. F., Vallotton, M. B., Timberg, R., Friedberg, I., Orly, J., Wang, X. J., Stocco, D. M., & Capponi, A. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.12.7899 · Cited by 175 · see citing works
Self-citationAdrenal cholesterol utilization
Kraemer, F. B. (2007) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.12.001 · Cited by 171 · see citing works
Fujieda, K., Tajima, T., Nakae, J., Sageshima, S., Tachibana, K., Suwa, S., Sugawara, T., & Strauss, J. F. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119284 · Cited by 162 · see citing works
Prasad, M., Kaur, J., Pawlak, K. J., Bose, M., Whittal, R. M., & Bose, H. S. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.605808 · Cited by 163 · see citing works
Profiling transcript levels for steroidogenic enzymes in fetal tissues
Pezzi, V., Mathis, J. M., Rainey, W. E., & Carr, B. R. (2003) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2003.07.006 · Cited by 156 · see citing works
Steroid deficiency syndromes in mice with targeted disruption of Cyp11a1
Hu, M.-C., Hsu, N.-C., El Hadj, N. B., Pai, C.-I., Chu, H.-P., Wang, C.-K. L., & Chung, B.-C. (2002) · Molecular Endocrinology · doi:10.1210/me.2002-0055 · Cited by 153 · see citing works
Miller, W. (1997) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0190227 · Cited by 147 · see citing works
Steroidogenic Acute Regulatory Protein
Christenson, L. K., & Strauss, J. F. (2001) · Archives of Medical Research · doi:10.1016/s0188-4409(01)00338-1 · Cited by 146 · see citing works
Raff, H., Sharma, S. T., & Nieman, L. K. (2014) · Comprehensive Physiology · doi:10.1002/cphy.c130035 · Cited by 141 · see citing works
Bose, M., Whittal, R. M., Miller, W. L., & Bose, H. S. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709221200 · Cited by 143 · see citing works
The adrenal peripheral clock: Glucocorticoid and the circadian timing system
Son, G. H., Chung, S., & Kim, K. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2011.07.003 · Cited by 136 · see citing works
Androgen synthesis in adrenarche
Miller, W. L. (2009) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-008-9102-4 · Cited by 127 · see citing works
Manna, P., Eubank, D., Lalli, E., Sassone-Corsi, P., & Stocco, D. (2003) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0300381 · Cited by 122 · see citing works
Self-citationKatsumata, N., Ohtake, M., Hojo, T., Ogawa, E., Hara, T., Sato, N., & Tanaka, T. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.8.8763 · Cited by 125 · see citing works
Current knowledge on the acute regulation of steroidogenesis
Selvaraj, V., Stocco, D. M., & Clark, B. J. (2018) · Biology of Reproduction · doi:10.1093/biolre/ioy102 · Cited by 118 · see citing works
Self-citationAdrenal Androgens and Androgen Precursors-Definition, Synthesis, Regulation and Physiologic Actions
Turcu, A., Smith, J. M., Auchus, R., & Rainey, W. E. (2014) · Comprehensive physiology · doi:10.1002/cphy.c140006 · Cited by 113 · see citing works
Narasaka, T., Suzuki, T., Moriya, T., & Sasano, H. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00445-7 · Cited by 109 · see citing works
Congenital lipoid adrenal hyperplasia
Kim, C. J. (2014) · Annals of Pediatric Endocrinology & Metabolism · doi:10.6065/apem.2014.19.4.179 · Cited by 105 · see citing works
Steroid Hormone Biosynthesis and Actions in the Materno Fetoplacental Unit
Miller, W. L. (1998) · Clinics in Perinatology · doi:10.1016/s0095-5108(18)30084-8 · Cited by 98 · see citing works
Biason-Lauber, A., Zachmann, M., & Schoenle, E. J. (2000) · Endocrinology · doi:10.1210/endo.141.4.7402 · Cited by 98 · see citing works
Cholesterol binding does not predict activity of the steroidogenic acute regulatory protein, StAR
Baker, B. Y., Epand, R. F., Epand, R. M., & Miller, W. L. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611221200 · Cited by 89 · see citing works
Sahakitrungruang, T., Soccio, R. E., Lang-Muritano, M., Walker, J. M., Achermann, J. C., & Miller, W. L. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0437 · Cited by 91 · see citing works
Mathieu, A., Fleury, A., Ducharme, L., Lavigne, P., & LeHoux, J. (2002) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0290327 · Cited by 82 · see citing works
Shea-Eaton, W. K., Trinidad, M. J., Lopez, D., Nackley, A., & McLean, M. P. (2001) · Endocrinology · doi:10.1210/endo.142.4.8075 · Cited by 80 · see citing works
Baker, B. Y., Yaworsky, D. C., & Miller, W. L. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m510241200 · Cited by 79 · see citing works
Duarte, A., Castillo, A. F., Podestá, E. J., & Poderoso, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100387 · Cited by 79 · see citing works
New insights into the controversy of adrenal function during critical illness
Boonen, E., Bornstein, S. R., & Van den Berghe, G. (2015) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(15)00224-7 · Cited by 77 · see citing works
Skin steroidogenesis in health and disease
Nikolakis, G., Stratakis, C. A., Kanaki, T., Slominski, A., & Zouboulis, C. C. (2016) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-016-9390-z · Cited by 76 · see citing works
Yaworsky, D. C., Baker, B. Y., Bose, H. S., Best, K. B., Jensen, L. B., Bell, J. D., Baldwin, M. A., & Miller, W. L. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m410937200 · Cited by 68 · see citing works
Tuckey, R. C., Headlam, M. J., Bose, H. S., & Miller, W. L. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206965200 · Cited by 67 · see citing works
Ragazzon, B., Lefrançois-Martinez, A.-M., Val, P., Sahut-Barnola, I., Tournaire, C., Chambon, C., Gachancard-Bouya, J.-L., Begue, R.-J., Veyssière, G., & Martinez, A. (2006) · Endocrinology · doi:10.1210/en.2005-1279 · Cited by 67 · see citing works
The molecular basis of premature adrenarche: an hypothesis
Miller, W. L. (1999) · Acta Paediatrica · doi:10.1111/j.1651-2227.1999.tb14405.x · Cited by 60 · see citing works
Anuka, E., Gal, M., Stocco, D. M., & Orly, J. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.02.003 · Cited by 60 · see citing works
Self-citationFlück, C. E., Martens, J. W. M., Conte, F. A., & Miller, W. L. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020501 · Cited by 57 · see citing works
Role of Mitochondria in Steroidogenesis
Miller, W. L. (2011) · Endocrine Development · doi:10.1159/000321204 · Cited by 57 · see citing works
Sasaki, G., Ishii, T., Jeyasuria, P., Jo, Y., Bahat, A., Orly, J., Hasegawa, T., & Parker, K. L. (2008) · Molecular Endocrinology · doi:10.1210/me.2007-0493 · Cited by 53 · see citing works
Jo, Y., & Stocco, D. M. (2004) · Endocrinology · doi:10.1210/en.2004-0941 · Cited by 45 · see citing works
Self-citationA brief history of adrenal research
Miller, W. L. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.10.023 · Cited by 44 · see citing works
Midzak, A., & Papadopoulos, V. (2014) · Traffic · doi:10.1111/tra.12177 · Cited by 38 · see citing works
Yoo, H.-W., & Kim, G.-H. (1998) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.1998.11.6.707 · Cited by 35 · see citing works
Glucocorticoid metabolism in the developing lung: adrenal-like synthesis pathway
Provost, P. R., Boucher, E., & Tremblay, Y. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.03.004 · Cited by 31 · see citing works
Bile acids and glucocorticoid metabolism in health and disease
Theiler-Schwetz, V., Zaufel, A., Schlager, H., Obermayer-Pietsch, B., Fickert, P., & Zollner, G. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.08.001 · Cited by 31 · see citing works
Neurosteroid influences on sensitivity to ethanol
Helms, C. M., Rossi, D. J., & Grant, K. A. (2012) · Frontiers in Endocrinology · doi:10.3389/fendo.2012.00010 · Cited by 30 · see citing works
Fudulu, D. P., Horn, G., Hazell, G., Lefrançois-Martinez, A.-M., Martinez, A., Angelini, G. D., Lightman, S. L., & Spiga, F. (2021) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2021.111195 · Cited by 11 · see citing works
Luo, Y., Bai, R., Wang, Z., Zhu, X., Xing, J., & Li, X. (2020) · Molecular Medicine Reports · doi:10.3892/mmr.2020.11140 · Cited by 7 · see citing works
Dynamics of the HPA Axis: A Systems Modeling Approach
Terry, J. R., Walker, J. J., Spiga, F., & Lightman, S. L. (2016) · Computational Neuroendocrinology · doi:10.1002/9781119159438.ch8 · Cited by 5 · see citing works
- Authors
- STOCCO, D. M., & CLARK, B. J.
- Affiliations
- Texas Tech University Health Sciences Center (US)
- Texas Tech University (US)
- Corresponding author
- STOCCO, DOUGLAS M.
- ORCID
- CLARK, BARBARA J.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 1996-06
- Volume
- 17
- Issue
- 3
- Pages
- 221-244
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2165101701
- Cited by
- 1,057
- References
- 147
- Citations by year
- 2026: 2 · 2025: 16 · 2024: 17 · 2023: 15 · 2022: 18 · 2021: 18 · 2020: 17 · 2019: 26 · 2018: 27 · 2017: 29 · 2016: 35 · 2015: 29 · 2014: 54 · 2013: 30 · 2012: 36
- FWCI
- 42.64
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Endocrine Reviews (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (1f32hd007688-01a1)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD17481, HD 07688)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
- Keywords
- steroidogenesis, steroidogenic cells, glucocorticoids, mineralocorticoids, androgens, progestins, estrogen, cholesterol side-chain cleavage, pregnenolone, trophic hormones
- MeSH terms
- Steroidogenic Acute Regulatory Protein, Adrenal Hyperplasia, Congenital, Animals, Gene Expression Regulation, Humans, Phosphoproteins, Steroids
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review