Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome — An allostatic perspective

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

(2002) · New England Journal of Medicine · doi:10.1056/nejmoa012512 · Cited by 19,011

Role of Insulin Resistance in Human Disease

Reaven, G. M. (1988) · Diabetes · doi:10.2337/diab.37.12.1595 · Cited by 12,154

Obesity is associated with macrophage accumulation in adipose tissue

Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Hotamisligil, G. S., Shargill, N. S., & Spiegelman, B. M. (1993) · Science · doi:10.1126/science.7678183 · Cited by 7,518

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057

Banting lecture 1988. Role of insulin resistance in human disease.

Reaven, G. (1988) · Diabetes · doi:10.2337/diabetes.37.12.1595 · Cited by 3,801

TLR4 links innate immunity and fatty acid-induced insulin resistance

Shi, H., Kokoeva, M. V., Inouye, K., Tzameli, I., Yin, H., & Flier, J. S. (2006) · Journal of Clinical Investigation · doi:10.1172/jci28898 · Cited by 3,690

The concept of allostasis in biology and biomedicine

McEwen, B. S., & Wingfield, J. C. (2003) · Hormones and Behavior · doi:10.1016/s0018-506x(02)00024-7 · Cited by 3,302

10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study

Diabetes Prevention Program Research Group (2009) · The Lancet · doi:10.1016/s0140-6736(09)61457-4 · Cited by 3,020

Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

Kahn, S. E., Haffner, S. M., Heise, M. A., Herman, W. H., Holman, R. R., Jones, N. P., Kravitz, B. G., Lachin, J. M., O'Neill, M. C., Zinman, B., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa066224 · Cited by 2,962

Seipin Deficiency as a Model of Severe Adipocyte Dysfunction: Lessons from Rodent Models and Teaching for Human Disease

Magré, J., & Prieur, X. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23020740 · Cited by 23

PGAM5 regulates DRP1-mediated mitochondrial fission/mitophagy flux in lipid overload-induced renal tubular epithelial cell necroptosis

Sang, D., Duan, X., Yu, X., Zang, J., Liu, L., & Wu, G. (2022) · Toxicology Letters · doi:10.1016/j.toxlet.2022.10.003 · Cited by 22

Positive feedback loop of miR-320 and CD36 regulates the hyperglycemic memory-induced diabetic diastolic cardiac dysfunction

Zhan, J., Jin, K., Ding, N., Zhou, Y., Guo, H., Yuan, S., Xie, R., Zheng, W., Chen, C., Li, H., et al. (2022) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2022.12.009 · Cited by 23

Obesity, Dietary Fats, and Gastrointestinal Cancer Risk-Potential Mechanisms Relating to Lipid Metabolism and Inflammation

Mitchelson, K. A. J., O’Connell, F., O'Sullivan, J. N., & Roche, H. M. (2024) · Metabolites · doi:10.3390/metabo14010042 · Cited by 25

Thermoneutrality results in prominent diet‐induced body weight differences in C57BL/6J mice, not paralleled by diet‐induced metabolic differences

Hoevenaars, F. P. M., Bekkenkamp‐Grovenstein, M., Janssen, R. J. R. J., Heil, S. G., Bunschoten, A., den Hil, E. F. H.-V., Snaas‐Alders, S., Teerds, K. J., van Schothorst, E. M., & Keijer, J. (2013) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201300285 · Cited by 23

Metabolic Control by S6 Kinases Depends on Dietary Lipids

Castañeda, T. R., Abplanalp, W. A., Um, S. H., Pfluger, P. T., Schrott, B., Brown, K., Grant, E., Carnevalli, L. S., Benoit, S. C., Morgan, D. A., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032631 · Cited by 23

Adipose tissue hyperplasia with enhanced adipocyte-derived stem cell activity in Tc1(C8orf4)-deleted mice

Jang, H.-Y., Kim, M., Lee, S., Kim, J., Woo, D., Kim, K. W., Song, K., & Lee, I. (2016) · Scientific Reports · doi:10.1038/srep35884 · Cited by 24

Histone demethylase KDM1A represses inflammatory gene expression in preadipocytes

Hanzu, F. A., Musri, M. M., Sánchez‐Herrero, A., Claret, M., Esteban, Y., Kaliman, P., Gomis, R., & Párrizas, M. (2013) · Obesity · doi:10.1002/oby.20479 · Cited by 24

Obesity and psychotic disorders: uncovering common mechanisms through metabolomics

Orešič, M. (2012) · Disease Models & Mechanisms · doi:10.1242/dmm.009845 · Cited by 23

Nontraditional Risk Factors for Obesity in Modern Society

Han, S.-J., & Lee, S. (2021) · Journal of Obesity & Metabolic Syndrome · doi:10.7570/jomes21004 · Cited by 23

The Role of Individually Selected Diets in Obese Women with PCOS—A Review

Chudzicka-Strugała, I., Gołębiewska, I., Banaszewska, B., Brudecki, G. P., & Zwoździak, B. (2022) · Nutrients · doi:10.3390/nu14214555 · Cited by 25

Therapeutic potential of antisense oligonucleotides for the management of dyslipidemia

Carpentier, A. C., Labbé, S. M., Grenier–Larouche, T., & Noll, C. (2011) · Clinical Lipidology · doi:10.2217/clp.11.60 · Cited by 23

Mouse Models of Lipodystrophy and Their Significance in Understanding Fat Regulation

Rochford, J. J. (2014) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-397920-9.00005-6 · Cited by 23

Dietary calories and lipids synergistically shape adipose tissue cellularity during postnatal growth

Meln, I., Wolff, G., Gajek, T., Koddebusch, J., Lerch, S., Harbrecht, L., Hong, W., Bayindir‐Buchhalter, I., Krunic, D., Augustin, H. G., et al. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.03.012 · Cited by 22

Isoimperatorin enhances 3T3‑L1 preadipocyte differentiation by regulating PPARγ and C/EBPα through the Akt signaling pathway

Jiang, T., Shi, X., Yan, Z., Wang, X., & Gun, S. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.7820 · Cited by 22

The “adipose tissue expandability” hypothesis: a potential mechanism for insulin resistance in obese youth

Caprio, S., Pierpont, B. M., & Kursawe, R. (2018) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2018-0005 · Cited by 22

Adipose Tissue Dysfunction Determines Lipotoxicity and Triggers the Metabolic Syndrome: Current Challenges and Clinical Perspectives

Carobbio, S., Pellegrinelli, V., & Vidal‐Puig, A. (2024) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-63657-8_8 · Cited by 23

Preproghrelin expression is a key target for insulin action on adipogenesis

Gurriarán‐Rodríguez, U., Al–Massadi, O., Crujeiras, A. B., Mosteiro, C. S., Amil, M., Beiroa, D., Nogueiras, R., Seoane, L. M., Gallego, R., Pazos, Y., et al. (2011) · Journal of Endocrinology · doi:10.1530/joe-11-0233 · Cited by 21

A higher proportion of small adipocytes is associated with increased visceral and ectopic lipid accumulation during weight gain in response to overfeeding in men

White, U. A., Beyl, R. A., & Ravussin, É. (2022) · International Journal of Obesity · doi:10.1038/s41366-022-01150-y · Cited by 24

Influence of environment variations on anti-glycaemic, anti-cholesterolemic, antioxidant and antimicrobial activities of natural wild fruits of Ziziphus lotus (L.).

Dahlia, F., Barouagui, S., Hemida, H., Bousaadia, D., & Rahmoune, B. (2020) · South African Journal of Botany · doi:10.1016/j.sajb.2020.04.033 · Cited by 23

Additive Effects of Omega-3 Fatty Acids and Thiazolidinediones in Mice Fed a High-Fat Diet: Triacylglycerol/Fatty Acid Cycling in Adipose Tissue

Bardová, K., Funda, J., Pohl, R., Čajka, T., Hensler, M., Kuda, O., Janovská, P., Adamcová, K., Irodenko, I., Lenkova, L., et al. (2020) · Nutrients · doi:10.3390/nu12123737 · Cited by 24

Epicardial Steatosis, Insulin Resistance, and Coronary Artery Disease

Toth, P. P. (2012) · Heart Failure Clinics · doi:10.1016/j.hfc.2012.06.013 · Cited by 21

ApoB-lipoproteins and dysfunctional white adipose tissue: Relation to risk factors for type 2 diabetes in humans

Lamantia, V., Bissonnette, S., Wassef, H., Cyr, Y., Baass, A. W., Dufour, R., RABASA-LHORET, R. P. R., & Faraj, M. (2016) · Journal of clinical lipidology · doi:10.1016/j.jacl.2016.09.013 · Cited by 21

Obesity Defined as Excess Storage of Inert Triglycerides – Do We Need a Paradigm Shift?

Sørensen, T. I. A. (2011) · Obesity Facts · doi:10.1159/000328198 · Cited by 21

Isthmin-1 (ISM1), a novel adipokine that reflects abdominal adipose tissue distribution in individuals with obesity

Lopez‐Yus, M., Casamayor, C., Soriano-Godes, J. J., Ansón, S. B., Gonzalez-Irazabal, Y., García-Sobreviela, M. P., Garcia-Rodriguez, B., del Moral, R., Calmarza, P., Artigas, J. M., et al. (2023) · Cardiovascular Diabetology · doi:10.1186/s12933-023-02075-0 · Cited by 20

Role of systemic and epicardial adipose tissue in cardiometabolic disease

Khanna, S., Mann, G. V., Bhat, A., Lin, A., Patel, A., Nicholls, S. J., Sindone, A. P., Dey, D., Bhatt, D. L., Arnott, C. G., et al. (2026) · Nature Reviews Cardiology · doi:10.1038/s41569-026-01304-9 · Cited by 27

VLDL triglyceride accumulation in skeletal muscle and adipose tissue in type 2 diabetes

Søndergaard, E., & Nielsen, S. (2017) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000471 · Cited by 20

Whole-slide image analysis outperforms micrograph acquisition for adipocyte size quantification

Maguire, A. S., Woodie, L. N., Judd, R. L., Martin, D. R., Greene, M. W., & Graff, E. C. (2020) · Adipocyte · doi:10.1080/21623945.2020.1823139 · Cited by 20

Up‐Regulation of Stearoyl‐CoA Desaturase 1 Increases Liver MUFA Content in Obese Zucker but Not Goto‐Kakizaki Rats

Karahashi, M., Ishii, F., Yamazaki, T., Imai, K., Mitsumoto, A., Kawashima, Y., & Kudo, N. (2013) · Lipids · doi:10.1007/s11745-013-3786-2 · Cited by 20

The MRC1/CD68 Ratio Is Positively Associated with Adipose Tissue Lipogenesis and with Muscle Mitochondrial Gene Expression in Humans

Moreno‐Navarrete, J. M., Ortega, F. J., Gómez‐Serrano, M., García‐Santos, E., Ricart, W., Tinahones, F. J., Mingrone, G., Peral, B., & Fernández‐Real, J. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070810 · Cited by 21

Pathogenesis of the Metabolic Syndrome: Insights from Monogenic Disorders

Murphy, R., Carroll, R. W., & Krebs, J. D. (2013) · Mediators of Inflammation · doi:10.1155/2013/920214 · Cited by 22

Predominant Role of GIP in the Development of a Metabolic Syndrome-like Phenotype in Female Wistar Rats Submitted to Forced Catch-up Growth

de Toro‐Martín, J., Fernández‐Millán, E., Lizárraga-Mollinedo, E., López‐Oliva, M. E., Serradas, P., Escrivá, F., & Álvarez, C. (2014) · Endocrinology · doi:10.1210/en.2013-2043 · Cited by 20

Methods for Performing Lipidomics in White Adipose Tissue

Roberts, L. D., West, J. A., Vidal‐Puig, A., & Griffin, J. L. (2014) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-800280-3.00012-8 · Cited by 20

The Effects of Green Tea Consumption on Cardiometabolic Alterations Induced by Experimental Diabetes

Fiorino, P., Evangelista, F. S., dos Santos, F., Magri, F. M. M., Delorenzi, J. C. M. O. B., Ginoza, M., & Farah, V. (2012) · Experimental Diabetes Research · doi:10.1155/2012/309231 · Cited by 20

AdipoScan: A Novel Transient Elastography-Based Tool Used to Non-Invasively Assess Subcutaneous Adipose Tissue Shear Wave Speed in Obesity

Sasso, M., Liu, Y., Aron‐Wisnewsky, J., Bouillot, J., Abdennour, M., Clet, M., Sandrin, L., Naour, G. L., Bédossa, P., Tordjman, J., et al. (2016) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2016.06.016 · Cited by 20

Dietary fat differentially influences the lipids storage on the adipose tissue in metabolic syndrome patients

Camargo, A., Meneses, M. E. P. D., Pérez‐Martínez, P., Delgado‐Lista, J., Jiménez, Y., Cruz‐Teno, C., Tinahones, F. J., Paniagua, J. A., Pérez‐Jiménez, F., Roche, H. M., et al. (2013) · European Journal of Nutrition · doi:10.1007/s00394-013-0570-2 · Cited by 18

Is insulin resistance tissue-dependent and substrate-specific? The role of white adipose tissue and skeletal muscle

Calderón-DuPont, D., Torre-Villalvazo, I., & Díaz‐Villaseñor, A. (2022) · Biochimie · doi:10.1016/j.biochi.2022.08.021 · Cited by 23

The fat body cortical actin network regulates Drosophila inter-organ nutrient trafficking, signaling, and adipose cell size

Ugrankar, R., Tran, S., Bowerman, J., Коваленко, А., Paul, B., & Henne, W. M. (2023) · eLife · doi:10.7554/elife.81170 · Cited by 19

Progression to Obesity: Variations in Patterns of Metabolic Fluxes, Fat Accumulation, and Gastrointestinal Responses

Milhem, F., & Komarnytsky, S. (2023) · Metabolites · doi:10.3390/metabo13091016 · Cited by 21

Adipose Tissue, Inflammation (Meta-inflammation) and Obesity Management

Meiliana, A., Dewi, N. M., & Wijaya, A. (2015) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v7i3.185 · Cited by 19

Nilotinib-induced metabolic dysfunction: insights from a translational study using in vitro adipocyte models and patient cohorts

Sadiq, S., Owen, E., Foster, T., Knight, K., Wang, L., Pirmohamed, M., Clark, R. E., & Pushpakom, S. P. (2019) · Leukemia · doi:10.1038/s41375-018-0337-0 · Cited by 19

Myeloid sirtuin1 deficiency aggravates hippocampal inflammation in mice fed high-fat diets

Kim, K. E., Jeong, E. A., Lee, J. Y., Yi, C., Park, K.-A., Jin, Z. H., Lee, J. E., Horváth, T. L., & Roh, G. S. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.04.044 · Cited by 19

Optimal cut‐points of visceral adipose tissue areas for cardiometabolic risk factors in a Chinese population: a cross‐sectional study

Huo, L., Li, K., Deng, W., Wang, L., Xu, L., Shaw, J. E., Jia, P., Zhou, D., & Cheng, X. (2019) · Diabetic Medicine · doi:10.1111/dme.14060 · Cited by 19

The prothrombotic state associated with obesity-induced hypertension is reduced by cocoa and its main flavanols

Rabadán-Chávez, G. M., Reyes‐Maldonado, E., Quevedo-Corona, L., Paniagua‐Castro, N., Escalona-Cardoso, G. N., & Jaramillo‐Flores, M. E. (2016) · Food & Function · doi:10.1039/c6fo01165a · Cited by 19

Ceramide-induced FGF13 impairs systemic metabolic health

Naderi, J., Johnson, A. K., Thakkar, H., Chandravanshi, B., Ksiazek, A., Anand, A., Vincent, V., Tran, A., Kalimireddy, A., Singh, P., et al. (2025) · Cell Metabolism · doi:10.1016/j.cmet.2025.03.002 · Cited by 22

Dietary control of peripheral adipose storage capacity through membrane lipid remodelling

Tol, M. J., Shimanaka, Y., Bedard, A. H., Sapia, J. L., Cui, L., Colaço-Gaspar, M., Hofer, P., Ferrari, A., Qian, K., Kennelly, J. P., et al. (2025) · Nature Metabolism · doi:10.1038/s42255-025-01320-y · Cited by 21

Cardiometabolic Risk Assessments by Body Mass Indexz-Score or Waist-to-Height Ratio in a Multiethnic Sample of Sixth-Graders

Kahn, H. S., ghormli, L. K. E., Jago, R., Foster, G. D., McMurray, R. G., Buse, J. B., Stadler, D. D., Treviño, R. P., Baranowski, T., & Healthy Study Group (2014) · Journal of Obesity · doi:10.1155/2014/421658 · Cited by 19

Sex differences in white adipose tissue expansion: emerging molecular mechanisms

Bond, S. T., Calkin, A. C., & Drew, B. G. (2021) · Clinical Science · doi:10.1042/cs20210086 · Cited by 18

Therapeutic ketosis decreases methacholine hyperresponsiveness in mouse models of inherent obese asthma

Mank, M. M., Reed, L. F., Walton, C. J., Barup, M. L. T., Ather, J. L., & Poynter, M. E. (2021) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00309.2021 · Cited by 17

Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice

Morine, M. J., Toomey, S., McGillicuddy, F. C., Reynolds, C. M., Power, K. A., Browne, J. A., Loscher, C. E., Mills, K. H. G., & Roche, H. M. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2012.04.012 · Cited by 18

Liver-specific insulin receptor isoform A expression enhances hepatic glucose uptake and ameliorates liver steatosis in a mouse model of diet-induced obesity

López‐Pastor, A. R., Gómez‐Hernández, A., Díaz-Castroverde, S., González‐Aseguinolaza, G., Gonzalez-Rodriguez, A., Garcia, G., Fernández, S., Escribano, Ó., & Benito, M. (2019) · Disease Models & Mechanisms · doi:10.1242/dmm.036186 · Cited by 18

Acute Aerobic Exercise Remodels the Adipose Tissue Progenitor Cell Phenotype in Obese Adults

Ludzki, A. C., Krueger, E. M., Baldwin, T. C., Schleh, M. W., Porsche, C. E., Ryan, B. J., Muir, L. A., Singer, K., Lumeng, C. N.-K., & Horowitz, J. F. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00903 · Cited by 17

Reprint of: Recent Updates on Obesity Treatments: Available Drugs and Future Directions

Dragano, N. R. V., Fernø, J., Diéguez, C., López, M., & Milbank, E. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.08.009 · Cited by 18

The Influence of Obesity and Weight Loss on the Bioregulation of Innate/Inflammatory Responses: Macrophages and Immunometabolism

Gálvez, I., Navarro, M. D. C., Martín-Cordero, L., Otero, E., Hinchado, M. D., & Ortega, E. (2022) · Nutrients · doi:10.3390/nu14030612 · Cited by 21

Effects of Neonatal Programming on Hypothalamic Mechanisms Controlling Energy Balance

Contreras, C., Novelle, M. G., Leis, R., Diéguez, C., Skrede, S., & López, M. (2013) · Hormone and Metabolic Research · doi:10.1055/s-0033-1351281 · Cited by 18

Prostaglandin F2α Inhibits Adipogenesis Via an Autocrine‐Mediated Interleukin‐11/Glycoprotein 130/STAT1‐Dependent Signaling Cascade

Annamalai, D., & Clipstone, N. A. (2014) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24785 · Cited by 19

Predictors of Insulin Resistance in Pediatric Burn Injury Survivors 24 to 36 Months Postburn

Chondronikola, M., Meyer, W. J., Sidossis, L. S., Ojeda, S., Huddleston, J., Stevens, P., Børsheim, E., Suman-Vejas, O. E., Finnerty, C. C., & Herndon, D. N. (2014) · Journal of Burn Care & Research · doi:10.1097/bcr.0000000000000017 · Cited by 17

The effects of muscle mass and muscle quality on cardio-metabolic risk in peripubertal girls: a longitudinal study from childhood to early adulthood

Cheng, S., & Wiklund, P. (2017) · International Journal of Obesity · doi:10.1038/ijo.2017.267 · Cited by 20

Resistin Increases Ectopic Deposition of Lipids Through miR-696 in C2C12 Cells

Wen, F., Zhang, H., Bao, C., Yang, M., Wang, N., Zhang, J., Hu, Y., Yang, X., Geng, J., & Yang, Z. (2015) · Biochemical Genetics · doi:10.1007/s10528-015-9672-2 · Cited by 18

Reduced Number of Adipose Lineage and Endothelial Cells in Epididymal fat in Response to Omega-3 PUFA in Mice Fed High-Fat Diet

Adamcová, K., Horakova, O., Bardová, K., Janovská, P., Březinová, M., Kuda, O., Rossmeisl, M., & Kopecký, J. (2018) · Marine Drugs · doi:10.3390/md16120515 · Cited by 17

New concepts in the roles of AMPK in adipocyte stem cell biology

Pollard, A. E. (2024) · Essays in Biochemistry · doi:10.1042/ebc20240008 · Cited by 11

A possible role of cystatin C in adipose tissue homeostasis may impact kidney function estimation in metabolic syndrome

de Vries, A. P. J., & Rabelink, T. J. (2012) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfs571 · Cited by 17

Chronic and degenerative diseases Obesity, inflammation and the immune system

de Heredia, F. P., NEZ, S. G. O. M.-M. I., & Marcos, A. (2012) · Cited by 17

Fat, yet fit

Vasan, S. K., & Karpe, F. (2016) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.77 · Cited by 17

Genetic risk scores for body fat distribution attenuate weight loss in women during dietary intervention

Svendstrup, M., Allin, K. H., Sørensen, T. I. A., Hansen, T. H., Grarup, N., Hansen, T. H., & Vestergaard, H. (2017) · International Journal of Obesity · doi:10.1038/ijo.2017.279 · Cited by 17

Impact of Progerin Expression on Adipogenesis in Hutchinson—Gilford Progeria Skin-Derived Precursor Cells

Najdi, F., Krüger, P., & Djabali, K. (2021) · Cells · doi:10.3390/cells10071598 · Cited by 19

Fatty acid composition of commercially available nutrition supplements

Staňková, B., Kremmyda, L.-S., TVRZICKÁ, E., & Žák, A. (2013) · Czech Journal of Food Sciences · doi:10.17221/276/2012-cjfs · Cited by 17

In-vivo metabolic studies of regional adipose tissue

Melvin, A., & McQuaid, S. (2018) · Cardiovascular Endocrinology & Metabolism · doi:10.1097/xce.0000000000000154 · Cited by 16

The Involvement of Selenium in Type 2 Diabetes Development Related to Obesity and Low Grade Inflammation

Wongdokmai, R., Shantavasinkul, P. C., Chanprasertyothin, S., Panpunuan, P., Matchariyakul, D., Sritara, P., & Sirivarasai, J. (2021) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s303146 · Cited by 15

Markers of adipose tissue fibrogenesis associate with clinically significant liver fibrosis and are unchanged by synbiotic treatment in patients with NAFLD

Bilson, J., Oquendo, C. J., Read, J., Scorletti, E., Afolabi, P. R., Lord, J., Bindels, L. B., Targher, G., Mahajan, S., Baralle, D., et al. (2023) · Metabolism · doi:10.1016/j.metabol.2023.155759 · Cited by 16

The role of PCSK9 in glomerular lipid accumulation and renal injury in diabetic kidney disease

Wu, M., Yoon, C.-Y., Park, J., Kim, G., Nam, B. Y., Kim, S., Park, J. T., Han, S. H., Kang, S., & Yoo, T. (2024) · Diabetologia · doi:10.1007/s00125-024-06191-8 · Cited by 16

Searching for ways to switch on brown fat: are we getting warmer?

Whittle, A. J. (2012) · Journal of Molecular Endocrinology · doi:10.1530/jme-12-0080 · Cited by 16

Fat storage‐inducing transmembrane protein 2 (FIT2) is less abundant in type 2 diabetes, and regulates triglyceride accumulation and insulin sensitivity in adipocytes

Agrawal, M., Yeo, C. R., Shabbir, A., Chhay, V., Silver, D. L., Magkos, F., Vidal‐Puig, A., & Toh, S.-A. E. S. (2018) · The FASEB Journal · doi:10.1096/fj.201701321rr · Cited by 16

Exercise reduced the formation of new adipocytes in the adipose tissue of mice in vivo

Allerton, T. D., Savoie, J. J., Fitch, M. D., Hellerstein, M. K., Stephens, J. M., & White, U. A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0244804 · Cited by 16

Psychoneuroimmunology of mental disorders

Soria, V., Uribe, J., Salvat‐Pujol, N., Palao, D. J., Menchón, J. M., & Labad, J. (2018) · Revista de Psiquiatría y Salud Mental (English Edition) · doi:10.1016/j.rpsmen.2017.07.002 · Cited by 17

Lipid mediators and inflammation in glucose intolerance and insulin resistance

Iyer, A., & Brown, L. (2010) · Drug Discovery Today Disease Mechanisms · doi:10.1016/j.ddmec.2010.12.001 · Cited by 16

Harveian Oration 2016: Some observations on the causes and consequences of obesity

O’Rahilly, S. (2016) · Clinical Medicine · doi:10.7861/clinmedicine.16-6-551 · Cited by 16

GATA-3 as a Potential Therapeutic Target for Insulin Resistance and Type 2 Diabetes Mellitus

Al-Jaber, H., Al-Mansoori, L., & Elrayess, M. A. (2020) · Current Diabetes Reviews · doi:10.2174/1573399816666200705210417 · Cited by 17

Breaking barriers in obesity research: 3D models of dysfunctional adipose tissue

Negrini, N. C., Pellegrinelli, V., Salem, V., Celiz, A. D., & Vidal‐Puig, A. (2024) · Trends in biotechnology · doi:10.1016/j.tibtech.2024.09.017 · Cited by 16

Cytoskeletal transgelin 2 contributes to gender‐dependent adipose tissue expandability and immune function

Ortega, F. J., Moreno‐Navarrete, J. M., Mercader, J. M., Gómez‐Serrano, M., García‐Santos, E., Latorre, J., Lluch, A., Sabater, M., Caballano‐Infantes, E., Guzmán‐Ruiz, R., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201900479r · Cited by 15

Calorie Restriction and SIRT1 Overexpression Induce Different Gene Expression Profiles in White Adipose Tissue in Association with Metabolic Improvement

Pardo, R., Velilla, M., Herrero, L., Cervela‐Cardona, L., Ribeiro, M. L., Simó, R., & Villena, J. A. (2021) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202000672 · Cited by 15

Postprandial consequences of lipid absorption in the onset of obesity: Role of intestinal CD36

Lebrun, L. J., Milheiro, S. M., Tavernier, A., & Niot, I. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2022.159154 · Cited by 16

Exploring the sequential accumulation of metabolic syndrome components in adults

Fernández‐Verdejo, R., & Galgani, J. E. (2022) · Scientific Reports · doi:10.1038/s41598-022-19510-z · Cited by 15

Depot-specific adipose tissue modulation by SGLT2 inhibitors and GLP1 agonists mediates their cardioprotective effects in metabolic disease

Bakkar, N. Z., AlZaim, I., & EL‐Yazbi, A. F. (2022) · Clinical Science · doi:10.1042/cs20220404 · Cited by 19

Maternal Exercise Protects Male Offspring From Maternal Diet–Programmed Nonalcoholic Fatty Liver Disease Progression

Hinrichs, H., Faerber, A., Young, M., Ballentine, S. J., & Thompson, M. D. (2023) · Endocrinology · doi:10.1210/endocr/bqad010 · Cited by 15

Chemoprevention of obesity-related liver carcinogenesis by using pharmaceutical and nutraceutical agents

Sakai, H. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i1.394 · Cited by 15

Long-Term Improvement in Aortic Pulse Wave Velocity After Weight Loss Can Be Predicted by White Adipose Tissue Factors

Bäckdahl, J., Andersson, D. P., Hogling, D. E., Caidahl, K., Thorell, A., Mileti, E., Daub, C. O., Arner, P., & Rydén, M. (2017) · American Journal of Hypertension · doi:10.1093/ajh/hpx201 · Cited by 15

Pathophysiological Features of Obesity and its Impact on Cognition: Exercise Training as a Non-Pharmacological Approach

Inoue, D. S., Antunes, B. M., Maideen, M. F. B., & Lira, F. S. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200114102524 · Cited by 17

Naringin treatment improved main clozapine‐induced adverse effects in rats; emphasis on weight gain, metabolic abnormalities, and agranulocytosis

George, M. Y., Menze, E. T., Esmat, A., Tadros, M. G., & El‐Demerdash, E. (2021) · Drug Development Research · doi:10.1002/ddr.21800 · Cited by 15

Changes in mechanical properties of adipose tissue after bariatric surgery driven by extracellular matrix remodelling and neovascularization are associated with metabolic improvements

Unamuno, X., Gómez‐Ambrosi, J., Becerril, S., Cienfuegos, F. J. Á., Ramírez, B., Rodrı́guez, A., Ezquerro, S., Valentí, V., Moncada, R., Mentxaka, A., et al. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.01.007 · Cited by 16

Deletion of TNF-like weak inducer of apoptosis (TWEAK) protects mice from adipose and systemic impacts of severe obesity

Bennett, G., Strissel, K. J., DeFuria, J., Wang, J., Wu, D., Burkly, L. C., & Obin, M. S. (2014) · Obesity · doi:10.1002/oby.20726 · Cited by 14

Glycemic index differences of high-fat diets modulate primarily lipid metabolism in murine adipose tissue

van Schothorst, E. M., Bunschoten, A., Verlinde, E., Schrauwen, P., & Keijer, J. (2011) · Physiological Genomics · doi:10.1152/physiolgenomics.00042.2011 · Cited by 15

Waist Circumference Is an Anthropometric Parameter That Identifies Women with Metabolically Unhealthy Phenotypes

Torres‐Castillo, N., Campos-Perez, W. Y., González‐Becerra, K., Hernández‐Cañaveral, I., Vizmanos-Lamotte, B., Muñóz-Valle, J. F., & Martínez‐López, E. (2018) · Nutrients · doi:10.3390/nu10040447 · Cited by 15

Tackling the effects of extracellular vesicles in fibrosis

Martín-Taboada, M., Corrales, P., Medina‐Gómez, G., & Vila‐Bedmar, R. (2022) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2022.151221 · Cited by 14

High Plasma Levels of Soluble Lectin‐like Oxidized Low‐Density Lipoprotein Receptor‐1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity

Stinson, S. E., Jonsson, A. E., Andersen, M. K., Lund, M. A. V., Holm, L. A., Fonvig, C. E., Huang, Y., Stankevič, E., Juel, H. B., Ängquist, L. H., et al. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.122.027042 · Cited by 14

Aquaporins in Obesity

da Silva, I. V., & Soveral, G. (2023) · Advances in experimental medicine and biology · doi:10.1007/978-981-19-7415-1_20 · Cited by 14

Associations of Trunk Fat Depots with Insulin Resistance, β Cell Function and Glycaemia - A Multiple Technique Study

Ganpule-Rao, A., Joglekar, C. V., Patkar, D. P., Chinchwadkar, M. C., Bhat, D., Lubree, H., Rege, S., Uradey, B. S., Yajnik, C. S., & Yudkin, J. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075391 · Cited by 14

Mitochondrial energetics in liver and skeletal muscle after energy restriction in young rats

Crescenzo, R., Bianco, F., Falcone, I., Coppola, P., Dulloo, A. G., Liverini, G., & Iossa, S. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511005903 · Cited by 14

The Triglyceride Content in Skeletal Muscle Is Associated with Hepatic But Not Peripheral Insulin Resistance in Elderly Twins

Grunnet, L. G., Laurila, E., Hansson, O., Almgren, P., Groop, L., Brøns, C., Poulsen, P., & Vaag, A. A. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-2061 · Cited by 14

Polycystic ovary syndrome in adolescent girls

Baldauff, N. H., & Witchel, S. F. (2016) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000309 · Cited by 14

An adipocentric perspective of pancreatic lipotoxicity in diabetes pathogenesis

Risi, R., Vidal‐Puig, A., & Bidault, G. (2024) · Journal of Endocrinology · doi:10.1530/joe-23-0313 · Cited by 18

Adipose Tissue Expandability in the Maintenance of Metabolic Homeostasis

Gray, S. L., & Vidal‐Puig, A. (2007) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00331.x · Cited by 231

Adipose tissue expandability and the metabolic syndrome

Slawik, M., & Vidal‐Puig, A. (2007) · Genes & Nutrition · doi:10.1007/s12263-007-0014-9 · Cited by 80

The Role of Adipose Tissue and Lipotoxicity in the Pathogenesis of Type 2 Diabetes

Cusi, K. J. (2010) · Current Diabetes Reports · doi:10.1007/s11892-010-0122-6 · Cited by 311

MECHANISMS IN ENDOCRINOLOGY: Skeletal muscle lipotoxicity in insulin resistance and type 2 diabetes: a causal mechanism or an innocent bystander?

Brøns, C., & Grunnet, L. G. (2016) · European Journal of Endocrinology · doi:10.1530/eje-16-0488 · Cited by 114