Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome — An allostatic perspective

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

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Role of Insulin Resistance in Human Disease

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Obesity is associated with macrophage accumulation in adipose tissue

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Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

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Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

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Banting lecture 1988. Role of insulin resistance in human disease.

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TLR4 links innate immunity and fatty acid-induced insulin resistance

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The concept of allostasis in biology and biomedicine

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10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study

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Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

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A Maternal High Fat Diet Has Long‐Lasting Effects on Skeletal Muscle Lipid and PLIN Protein Content in Rat Offspring at Young Adulthood

MacPherson, R. E. K., Castelli, L. M., Miotto, P. M., Frendo‐Cumbo, S., Milburn, A., Roy, B. D., LeBlanc, P. J., Ward, W. E., & Peters, S. J. (2014) · Lipids · doi:10.1007/s11745-014-3985-5 · Cited by 14

PRDM16 sustains white fat gene expression profile in human adipocytes in direct relation with insulin action

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Adipose Tissue Plasticity in Response to Pathophysiological Cues: A Connecting Link between Obesity and Its Associated Comorbidities

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Reaching the Tipping Point: Identification of Thresholds at which Visceral Adipose Tissue May Steeply Increase in Youth

Kelly, A. S., Kaizer, A. M., Bosch, T. A., Rudser, K. D., Ryder, J. R., Gross, A. C., Chow, L. S., Fox, C. K., & Dengel, D. R. (2019) · Obesity · doi:10.1002/oby.22679 · Cited by 13

Loss of Stearoyl-CoA desaturase 1 leads to cardiac dysfunction and lipotoxicity

Tuthill, B. F., Quaglia, C. J., O'Hara, E., & Musselman, L. P. (2021) · Journal of Experimental Biology · doi:10.1242/jeb.240432 · Cited by 12

The Parathyroid Hormone-Related Protein/Parathyroid Hormone 1 Receptor Axis in Adipose Tissue

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Antiobesity and Hepatoprotective Effects of Protein Hydrolysates Derived from Protaetia brevitarsis in an Obese Mouse Model

Lee, E. H., Chun, S. Y., Yoon, B. H., Han, M., Chung, J.-W., Ha, Y., Lee, J. N., Kim, H. T., Kim, D. H., Beik, G. Y., et al. (2022) · BioMed Research International · doi:10.1155/2022/4492132 · Cited by 13

The multifaceted functions of NFE2L1 in metabolism and associated disorders

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The Intestinal Thread of Fate: How the Microbiota Shapes the Story of Liver Disease

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A Contemporary Rationale for Agonism of the GIP Receptor in the Treatment of Obesity

Samms, R. J., & Sloop, K. W. (2025) · Diabetes · doi:10.2337/dbi24-0026 · Cited by 22

Characteristics of adipose tissue macrophages and macrophage-derived insulin-like growth factor-1 in virus-induced obesity

Park, S., Park, H.-L., Lee, S.-Y., & Jh, N. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.194 · Cited by 13

Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice

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Fillers and Facial Fat Pads

Wollina, U., Goldman, A., & Tchernev, G. (2017) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2017.117 · Cited by 14

RNA-Sequencing Analysis of Paternal Low-Protein Diet-Induced Gene Expression Change in Mouse Offspring Adipocytes

Ly, N. H., Maekawa, T., Yoshida, K., Liu, Y., Muratani, M., & Ishii, S. (2019) · G3 Genes Genomes Genetics · doi:10.1534/g3.119.400181 · Cited by 15

Vulpinic Acid Controls Stem Cell Fate toward Osteogenesis and Adipogenesis

Yi, S. A., Nam, K. H., Kim, S., So, H. M., Ryoo, R., Han, J., Kim, K. H., & Lee, J. (2019) · Genes · doi:10.3390/genes11010018 · Cited by 13

Beyond the Extracellular Vesicles: Technical Hurdles, Achieved Goals and Current Challenges When Working on Adipose Cells

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The Relation Between Adult Weight Gain, Adipocyte Volume, and the Metabolic Profile at Middle Age

Verkouter, I., Noordam, R., Loh, N. Y., van Dijk, K. W., Zock, P. L., Mook-Kanamori, D. O., le Cessie, S., Rosendaal, F. R., Karpe, F., Christodoulides, C., et al. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab477 · Cited by 11

Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes

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Delta-6 desaturase (Fads2) deficiency alters triacylglycerol/fatty acid cycling in murine white adipose tissue

Wang, C., Hucik, B., Sarr, O., Brown, L. H., Wells, K. R. D., Brunt, K. R., Nakamura, M., Harasim‐Symbor, E., Chabowski, A., & Mutch, D. M. (2023) · Journal of Lipid Research · doi:10.1016/j.jlr.2023.100376 · Cited by 13

Increased urinary aldosterone excretion is associated with subcutaneous not visceral, adipose tissue area in obese individuals: a possible manifestation of dysfunctional subcutaneous adipose tissue

Harada, E., Mizuno, Y., Katoh, D., Kashiwagi, Y., Morita, S., Nakayama, Y., Yoshimura, M., Masuzaki, H., Saito, Y., & Yasue, H. (2012) · Clinical Endocrinology · doi:10.1111/cen.12083 · Cited by 13

Adipose tissue metabolism and inflammation in obesity

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Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice

Ren, S., Hou, Y., Zuo, Z., Liu, Z., Wang, H., Xu, Y., Yamamoto, M. P., Zhang, Q., Fu, J., & Pi, J. (2020) · Food and Chemical Toxicology · doi:10.1016/j.fct.2020.111836 · Cited by 13

Impaired white adipose tissue fatty acid metabolism in mice fed a high-fat diet worsened by arsenic exposure, primarily affecting retroperitoneal adipose tissue

Calderón-DuPont, D., Romero-Cordoba, S. L., Tello, J. K., Espinosa, A., Guerrero, B., Contreras, A. V., Morán‐Ramos, S., & Díaz‐Villaseñor, A. (2023) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2023.116428 · Cited by 12

Alteration of BDNF, SPARC, FGF-21, and GDF-15 circulating levels after 1 year of anti-obesity treatments and their association with 1-year weight loss

Chaiyasoot, K., Khumkhana, N., Deekum, W., Chaichana, C., Taweerutchana, V., Srisuworanan, N., & Pramyothin, P. (2023) · Endocrine · doi:10.1007/s12020-023-03435-2 · Cited by 12

The Impact of Maternal Obesity on Adipose Progenitor Cells

Lecoutre, S., Maqdasy, S., Lambert, M., & Breton, C. (2023) · Biomedicines · doi:10.3390/biomedicines11123252 · Cited by 14

The Intersection of Genetic Factors, Aberrant Nutrient Metabolism and Oxidative Stress in the Progression of Cardiometabolic Disease

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Clinical and molecular insights into cardiovascular disease in psoriatic patients and the potential protective role of apremilast

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Bidirectional Mendelian Randomization Highlights Causal Relationships Between Circulating INHBC and Multiple Cardiometabolic Diseases and Traits

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Biology of metabolic syndrome in a vascular patient

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Ectopic Fat Deposition on Insulin Sensitivity: Correlation of Hepatocellular Lipid Content andMValue

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A Cecropia peltata ethanolic extract reduces insulin resistance and hepatic steatosis in rats fed a high-fat diet

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Adipocyte-specific deletion of zinc finger protein 407 results in lipodystrophy and insulin resistance in mice

Charrier, A., Xu, X., Guan, B., Ngo, J., Wynshaw-Boris, A. J., Hatzoglou, M., & Buchner, D. A. (2020) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2020.111109 · Cited by 11

The Combined Partial Knockdown of CBS and MPST Genes Induces Inflammation, Impairs Adipocyte Function-Related Gene Expression and Disrupts Protein Persulfidation in Human Adipocytes

Latorre, J., Aroca, Á., Fernández‐Real, J. M., Romero, L. C., & Moreno‐Navarrete, J. M. (2022) · Antioxidants · doi:10.3390/antiox11061095 · Cited by 12

Identification of novel targets in adipose tissue involved in non‐alcoholic fatty liver disease progression

Lopez‐Yus, M., Lorente‐Cebrián, S., del Moral, R., Hörndler, C., García-Sobreviela, M. P., Casamayor, C., Sanz‐París, A., Monterde, V. B., & Arbonés-Mainar, J. M. (2022) · The FASEB Journal · doi:10.1096/fj.202200118rr · Cited by 13

An adipocentric perspective of pancreatic lipotoxicity in diabetes pathogenesis

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Ethnic differences in the effects of hepatic fat deposition on insulin resistance in nonobese middle school girls

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Harnessing the beneficial properties of adipogenic microbes for improving human health

Dhurandhar, N. V., Geurts, L., Atkinson, R. L., Casteilla, L., Clément, K., Gérard, P., Vijay‐Kumar, M., Nam, J. H., Nieuwdorp, M., Trovato, G. M., et al. (2013) · Obesity Reviews · doi:10.1111/obr.12045 · Cited by 13

Adipogenic effect of calcium sensing receptor activation

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Mediators of Impaired Adipogenesis in Obesity-Associated Insulin Resistance and T2DM

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Effects of Lifestyle Intervention in Tissue-Specific Lipidomic Profile of Formerly Obese Mice

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Syndromes lipodystrophiques

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Arginine, soy isoflavone and hydroxypropylmethylcellulose have protective effects against obesity in broiler breeder hens fed on high-energy diets

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CRISPR/Cas9-mediated deletion of adipocyte genes associated with NAFLD alters adipocyte lipid handling and reduces steatosis in hepatocytes in vitro

Lopez‐Yus, M., Frendo‐Cumbo, S., del Moral, R., García-Sobreviela, M. P., Monterde, V. B., Rydén, M., Lorente‐Cebrián, S., & Arbonés-Mainar, J. M. (2023) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00291.2023 · Cited by 11

Diet-Induced Obesity Modulates Close-Packing of Triacylglycerols in Lipid Droplets of Adipose Tissue

Ko, K., Bandara, S. R., Zhou, W., Svenningsson, L., Porras-Gómez, M., Kambar, N., Dreher-Threlkeld, J., Topgaard, D., Hernández‐Saavedra, D., Anakk, S., et al. (2024) · Journal of the American Chemical Society · doi:10.1021/jacs.4c13420 · Cited by 11

Childhood obesity: The threatening apprentice of the adiposity empire

Cárdenas, J. K. Z., Gómez‐Ambrosi, J., & Frühbeck, G. (2025) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-025-09959-4 · Cited by 14

Gene expression of different adipose tissues of severely obese women with or without a dysmetabolic profile

Mauriège, P., Joanisse, D. R., Caspar‐Bauguil, S., Cartier, A., Lemieux, I., Bergeron, J., Biron, S., Marceau, P., & Richard, D. (2015) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-015-0436-6 · Cited by 11

Generation of a Novel Transgenic Zebrafish for Studying Adipocyte Development and Metabolic Control

Mao, Y., Hong, K., Liao, W., Li, L., Kim, S., Xiong, Y., Nam, I.-K., Choe, S., & Kwak, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22083994 · Cited by 11

New perspectives on obesity-induced adipose tissue fibrosis and related clinical manifestations

Hasegawa, Y. (2022) · Endocrine Journal · doi:10.1507/endocrj.ej22-0035 · Cited by 10

B Lymphocyte Stimulator (BLyS) Is Expressed in Human Adipocytes In Vivo and Is Related to Obesity but Not to Insulin Resistance

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Postprandial hypertriglyceridemia predicts improvement in insulin resistance in obese patients after bariatric surgery

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Lipophagy: A New Perspective of Natural Products in Type 2 Diabetes Mellitus Treatment

Huang, M., Yang, X., Wang, Z., Long, J., Wang, A., Zhang, Y., & Yan, D. (2021) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s310166 · Cited by 12

Sex differences in androgen regulation of metabolism in nonhuman primates

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Metabolic dysfunction-associated steatotic liver disease, cardiometabolic risk factors, and cardiovascular disease

Kyhl, L. K., Nordestgaard, B. G., Tybjærg‐Hansen, A., & Nielsen, S. F. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2025.120551 · Cited by 13

Tumoral acidosis promotes adipose tissue depletion by fostering adipocyte lipolysis

Lefevre, C., Thibaut, M. M., Loumaye, A., Thissen, J., Neyrinck, A. M., Navez, B., Delzenne, N. M., Féron, O., & Bindels, L. B. (2024) · Molecular Metabolism · doi:10.1016/j.molmet.2024.101930 · Cited by 10

Preventing White Adipocyte Browning during Differentiation In Vitro: The Effect of Differentiation Protocols on Metabolic and Mitochondrial Phenotypes

Herbers, E., Patrikoski, M., Wagner, A., Jokinen, R., Hassinen, A., Heinonen, S., Miettinen, S., Peltoniemi, H. H., Pirinen, E., & Pietiläinen, K. H. (2022) · Stem Cells International · doi:10.1155/2022/3308194 · Cited by 11

Discrepancies Between BMI and Classic Cardiovascular Risk Factors

van Mil, S. R., Vijgen, G. H. E. J., van Huisstede, A., Klop, B., van de Geijn, G. M., Birnie, E., Braunstahl, G., Mannaerts, G. H. H., Biter, L. U., & Cabezas, M. C. (2018) · Obesity Surgery · doi:10.1007/s11695-018-3359-9 · Cited by 10

CETP-derived Peptide Seq-1, the Key Component of HB-ATV-8 Vaccine Prevents Stress Responses, and Promotes Downregulation of Pro-Fibrotic Genes in Hepatocytes and Stellate Cells

Calixto-Tlacomulco, S., Luna-Reyes, I., Delgado‐Coello, B., Gutiérrez‐Vidal, R., Reyes‐Grajeda, J. P., & Mas‐Oliva, J. (2024) · Archives of Medical Research · doi:10.1016/j.arcmed.2023.102937 · Cited by 9

Type 2 diabetes: a sacrifice program handling energy surplus

Ye, J., & Yin, J. (2024) · Life Metabolism · doi:10.1093/lifemeta/loae033 · Cited by 9

Adipose tissue NLRP3 inflammasome: a therapeutic target in obesity and type 2 diabetes mellitus

Nnolum-Orji, N. F., Kumar, P., Ngema, L. M., & Choonara, Y. E. (2025) · Drug Discovery Today · doi:10.1016/j.drudis.2025.104456 · Cited by 13

On the Intimate Relationship of Adiposity to Polycystic Ovary Syndrome

Rosenfield, R. L., & Dumesic, D. A. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf527 · Cited by 11

Visceral adipose tissue and hepatic fat as determinants of carotid atherosclerosis

de Souza, R. J., Pigeyre, M., Schulze, K. M., Lamri, A., Al‐Khazraji, B. K., Awadalla, P., Beyene, J., Desai, D., Després, J., Dummer, T., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-01123-y · Cited by 10

How Adipocytes Orchestrate Inflammation Within Adipose Tissue?

Higos, R., Renzi, G., Taillandier, P., Merabtene, F., Rouault, C., Abatan, J. B., Lambert, M., Dugail, I., Clément, K., Marcelin, G., et al. (2025) · Biomolecules · doi:10.3390/biom16010059 · Cited by 12

Role of epicardial adipose tissue in diabetic cardiomyopathy through the lens of cardiovascular magnetic resonance imaging – a narrative review

Kotha, S., Plein, S., Greenwood, J. P., & Levelt, E. (2024) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/20420188241229540 · Cited by 11

Influence of Body Mass Index on the Activated Clotting Time Under Weight‐Based Heparin Dose

Hong, X., Shan, P., Huang, W., Zhu, Q., Xiao, F., Sheng, L., & Zhou, H. (2014) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.21823 · Cited by 9

Enhanced Therapeutic Potency of Nanoemulsified Garlic Oil Blend Towards Renal Abnormalities in Pre-diabetic Rats

Muralidaran, Y., Ragavan, G., Ganesh, R. N., & Viswanathan, P. (2018) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-018-2919-8 · Cited by 9

Epigenetic Regulation of Neuregulin-1 Tunes White Adipose Stem Cell Differentiation

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Improvement of glucose metabolism following rapid weight loss after bariatric surgery and its impact on reduction of visceral abdominal fat versus free fat muscle

Cogollo, V. J., Rivera, C. E., Valera, R. J., Sarmiento-Cobos, M. F., Montorfano, L. M., Wasser, E., Menzo, E. L., Szomstein, S., & Rosenthal, R. J. (2021) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2021.01.031 · Cited by 9

Genetic markers of abdominal obesity and weight loss after gastric bypass surgery

Aasbrenn, M., Svendstrup, M., Schnurr, T. M., Hansen, D. L., Worm, D., Balslev‐Harder, M., Grarup, N., Burgdorf, K. S., Vestergaard, H., Pedersen, O. B., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0252525 · Cited by 10

Short-Term Changes in Metabolically Healthy Overweight/Obesity Status Impact the Susceptibility to Type 2 Diabetes in Chinese Adults

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Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores

Liu, Y., Jiang, J., Ke, S., Milanesi, A., Abe, K., Gastelum, G., Li, J., & Brent, G. A. (2021) · Scientific Reports · doi:10.1038/s41598-021-03491-6 · Cited by 9

The role of adipogenic capacity and dysfunctional subcutaneous adipose tissue in the inheritance of type 2 diabetes mellitus: cross‐sectional study

Šiklová, M., Šrámková, V., Koc, M., Krauzová, E., Čížková, T., Ondrůjová, B., Wilhelm, M., Varaliová, Z., Kuda, O., Kračmerová, J., et al. (2024) · Obesity · doi:10.1002/oby.23969 · Cited by 9

Association of changes in the type 2 diabetes and MASLD /related SLD status with risk of developing cardiovascular disease

Matsubayashi, Y., Fujihara, K., KHIN, L. M., Ferreira, E. D. A., Takabayashi, S., Yamashita, Y., Yamada, T., Kodama, S., & Sone, H. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16196 · Cited by 8

Progranulin and tumor necrosis factor-alpha in lean polycystic ovary syndrome patients

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Birth weight was associated positively with gluteofemoral fat mass and inversely with 2-h postglucose insulin concentrations, a marker of insulin resistance, in young normal-weight Japanese women

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