Autophagy: Emerging roles in lipid homeostasis and metabolic control

Steatohepatitis: A tale of two “hits”?

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Autophagy regulates lipid metabolism

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Regulation mechanisms and signaling pathways of autophagy

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Functional Brown Adipose Tissue in Healthy Adults

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Obesity and the regulation of energy balance

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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

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Mammalian autophagy: core molecular machinery and signaling regulation

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Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

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An Overview of the Molecular Mechanism of Autophagy

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Autophagy regulates adipose mass and differentiation in mice

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Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues

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Mitochondrial abnormalities in non-alcoholic steatohepatitis

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Complexity in the Secretory Pathway: The Assembly and Secretion of Apolipoprotein B-containing Lipoproteins

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Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia

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Lipid droplets: a classic organelle with new outfits

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Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning

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Altered Autophagy in Human Adipose Tissues in Obesity

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Proteolytic and lipolytic responses to starvation

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Hepatic Overexpression of Hormone-sensitive Lipase and Adipose Triglyceride Lipase Promotes Fatty Acid Oxidation, Stimulates Direct Release of Free Fatty Acids, and Ameliorates Steatosis

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Cell biology of lipid droplets

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Targeted deletion of<i>autophagy-related 5</i>(<i>atg5</i>) impairs adipogenesis in a cellular model and in mice

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Mobilisation of triacylglycerol stores

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Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production

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GLP-1 Analogs Reduce Hepatocyte Steatosis and Improve Survival by Enhancing the Unfolded Protein Response and Promoting Macroautophagy

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Attenuated mTOR Signaling and Enhanced Autophagy in Adipocytes from Obese Patients with Type 2 Diabetes

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Obesity-induced Insulin Resistance and Hyperglycemia

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Lipid droplets as dynamic organelles connecting storage and efflux of lipids

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Synthesis and function of hepatic very-low-density lipoprotein

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Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis # †

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The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas

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Packaging of Fat: An Evolving Model of Lipid Droplet Assembly and Expansion

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Autophagy in nonalcoholic steatohepatitis

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Cytoplasmic Lipid Droplets Are Sites of Convergence of Proteasomal and Autophagic Degradation of Apolipoprotein B

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The Triple Threat to Nascent Apolipoprotein B

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Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span

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Loss of TGH/Ces3 in Mice Decreases Blood Lipids, Improves Glucose Tolerance, and Increases Energy Expenditure

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Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats

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Targeted disruption of the mouse lysosomal acid lipase gene: long-term survival with massive cholesteryl ester and triglyceride storage

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Origin of triacylglycerol moiety of plasma very low density lipoproteins in the rat: structural studies

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Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by autophagy: pathophysiological implications

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N-3 fatty acids stimulate intracellular degradation of apoprotein B in rat hepatocytes.

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Loss of Macroautophagy Promotes or Prevents Fibroblast Apoptosis Depending on the Death Stimulus

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Macroautophagy and Chaperone-Mediated Autophagy Are Required for Hepatocyte Resistance to Oxidant Stress

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Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: A pathway for late-stage quality control

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Cloning and expression of a cDNA encoding a hepatic microsomal lipase that mobilizes stored triacylglycerol

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Inhibitors of hepatic microsomal triacylglycerol hydrolase decrease very low density lipoprotein secretion

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Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assemblyThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.

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The many intersecting pathways underlying apolipoprotein B secretion and degradation

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Autophagy in mammalian cells

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Use of cytosolic triacylglycerol hydrolysis products and of exogenous fatty acid for the synthesis of triacylglycerol secreted by cultured rat hepatocytes

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Molecular machinery of macroautophagy and its deregulation in diseases

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Temporal and spatial variations of lipid droplets during adipocyte division and differentiation

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CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophaghy in HepG2 E47 cells

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Glucosamine-Induced Endoplasmic Reticulum Stress Promotes ApoB100 Degradation

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ER Stress and Lipid Metabolism in Adipocytes

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Autophagy-Lysosomal Pathway Is Involved in Lipid Degradation in Rat Liver

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Hepatic autophagy mediates endoplasmic reticulum stress–induced degradation of misfolded apolipoprotein B

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Cytoplasmic Lipid Droplets

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Contribution of cytoplasmic storage triacylglycerol to VLDL-triacylglycerol in isolated rat hepatocytes

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Apolipoprotein B and triacylglycerol secretion in human triacylglycerol hydrolase transgenic mice

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Mechanisms of glucosamine-induced suppression of the hepatic assembly and secretion of apolipoprotein B-100-containing lipoproteins

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The effects of n-3 fatty acids on the secretion of carboxyl-terminally truncated forms of human apoprotein B

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The Proteasomal and Autophagic Pathways Converge on Lipid Droplets

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Inhibition by chloroquine of the secretion of very low density lipoproteins by cultured rat hepatocytes

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Inhibition of very-low-density lipoprotein secretion by chloroquine, verapamil and monensin takes place in the Golgi complex

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Sugar consumption, metabolic disease and obesity: The state of the controversy

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Essential role for autophagy in life span extension

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Autophagy: An Essential Degradation Program for Cellular Homeostasis and Life

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Lipid Droplets in Cancer: Guardians of Fat in a Stressful World

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The small GTPase Rab7 as a central regulator of hepatocellular lipophagy

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Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy

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AMPK and autophagy in glucose/glycogen metabolism

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Lipid droplet proteins and metabolic diseases

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Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism

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Dose-dependent functionality and toxicity of green tea polyphenols in experimental rodents

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Linking Lipid Metabolism to Chromatin Regulation in Aging

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Apolipoproteins and cancer

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Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?

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Cannabidiol protects liver from binge alcohol-induced steatosis by mechanisms including inhibition of oxidative stress and increase in autophagy

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Deletion of autophagy inducer <i>RB1CC1</i> results in degeneration of the retinal pigment epithelium

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Crosstalk between Apoptosis and Autophagy: Molecular Mechanisms and Therapeutic Strategies in Cancer

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Recent insights into the molecular pathophysiology of lipid droplet formation in hepatocytes

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Role of autophagy in the pathophysiology of nonalcoholic fatty liver disease: A controversial issue

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Lipid droplet and its implication in cancer progression.

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Autophagosomes contribute to intracellular lipid distribution in enterocytes

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Pathways and mechanisms linking dietary components to cardiometabolic disease: thinking beyond calories

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The Influence of Probiotics on Zebrafish Danio Rerio Innate Immunity and Hepatic Stress

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The Classification and Basic Processes of Autophagy

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Aerobic endurance training improves nonalcoholic fatty liver disease (NAFLD) features via miR-33 dependent autophagy induction in high fat diet fed mice

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Alkyne-Azide “Click” Chemistry in Designing Nanocarriers for Applications in Biology

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