The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
The yeast lysosome-like vacuole: Endpoint and crossroads
Open accessAbstract
Summary Fungal vacuoles are acidic organelles with degradative and storage capabilities that have many similarities to mammalian lysosomes and plant vacuoles. In the past several years, well-developed genetic, genomic, biochemical and cell biological tools in S. cerevisiae have provided fresh insights into vacuolar protein sorting, organelle acidification, ion homeostasis, autophagy, and stress-related functions of the vacuole, and these insights have often found parallels in mammalian lysosomes. This review provides a broad overview of the defining features and functions of S. cerevisiae vacuoles and compares these features to mammalian lysosomes. Recent research challenges the traditional view of vacuoles and lysosomes as simply the terminal compartment of biosynthetic and endocytic pathways (i.e. the “garbage dump” of the cell), and suggests instead that these compartments are unexpectedly dynamic and highly regulated.
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Cited by
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The lysosome as a cellular centre for signalling, metabolism and quality control
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BackgroundAutophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications
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BackgroundPex30-dependent membrane contact sites maintain ER lipid homeostasis
Ferreira, J. V., Ahmed, Y., Heunis, T., Jain, A., Johnson, E., Räschle, M., Ernst, R., Vanni, S., & Carvalho, P. (2025) · Journal of Cell Biology · doi:10.1083/jcb.202409039 · Cited by 7
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Membrane contact sites regulate vacuolar fission via sphingolipid metabolism
Hanaoka, K., Nishikawa, K., Ikeda, A., Schlarmann, P., Yamashita, S., Nakaji, A., Fujii, S., & Funato, K. (2023) · doi:10.1101/2023.06.21.546015
Metadata
- Authors
- Li, S. C., & Kane, P. M.
- Venue
- Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Publisher
- Elsevier BV
- Published
- 2009-04
- Volume
- 1793
- Issue
- 4
- Pages
- 650-663
- ISSN
- 0167-4889 (ISSN-L)
- OpenAlex
- W2141747730
- Cited by
- 453
- References
- 8
- FWCI
- 4.60
- Type
- journal article
- Language
- en
- Open access
- bronze
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