The DOI matches its Crossref record; 68 of the 70 references it cites were found in a registry or an index.
Omega-3 supplementation lowers inflammation and anxiety in medical students: A randomized controlled trial
Open accessAbstract
Observational studies have linked lower omega-3 (n-3) polyunsaturated fatty acids (PUFAs) and higher omega-6 (n-6) PUFAs with inflammation and depression, but randomized controlled trial (RCT) data have been mixed. To determine whether n-3 decreases proinflammatory cytokine production and depressive and anxiety symptoms in healthy young adults, this parallel group, placebo-controlled, double-blind 12-week RCT compared n-3 supplementation with placebo. The participants, 68 medical students, provided serial blood samples during lower-stress periods as well as on days before an exam. The students received either n-3 (2.5 g/d, 2085 mg eicosapentaenoic acid and 348 mg docosahexanoic acid) or placebo capsules that mirrored the proportions of fatty acids in the typical American diet. Compared to controls, those students who received n-3 showed a 14% decrease in lipopolysaccharide (LPS) stimulated interleukin 6 (IL-6) production and a 20% reduction in anxiety symptoms, without significant change in depressive symptoms. Individuals differ in absorption and metabolism of n-3 PUFA supplements, as well as in adherence; accordingly, planned secondary analyses that used the plasma n-6:n-3 ratio in place of treatment group showed that decreasing n-6:n-3 ratios led to lower anxiety and reductions in stimulated IL-6 and tumor necrosis factor alpha (TNF-α) production, as well as marginal differences in serum TNF-α. These data suggest that n-3 supplementation can reduce inflammation and anxiety even among healthy young adults. The reduction in anxiety symptoms associated with n-3 supplementation provides the first evidence that n-3 may have potential anxiolytic benefits for individuals without an anxiety disorder diagnosis. ClinicalTrials.gov identifier: NCT00519779.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Although omega-3 supplementation was unrelated to changes in depression in this study”
From From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. (2014) · cites this paper as Kiecolt-Glaser, Belury, Andridge, Malarkey, & Glaser, 2011
The cited source says what the claim attributes to it.
In the citing paper
“medical students who received omega-3 supplementation exhibited a 14% reduction in LPS-stimulated IL-6 production and a 20% reduction in anxiety symptoms compared to those in the control group”
From From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. (2014) · cites this paper as Kiecolt-Glaser, Belury, Andridge, Malarkey, & Glaser, 2011
In the citing paper
“various RCTs have shown that omega-3 fatty acid supplementation reduces inflammation142–144 and may thus have health-promoting effects141–144”
From Chronic inflammation in the etiology of disease across the life span (2019) · cites this paper as [142]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION
Bligh, E. G., & Dyer, W. J. (1959) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/o59-099 · Cited by 54,751
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267
The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90047-4 · Cited by 35,234
An inventory for measuring clinical anxiety: Psychometric properties.
Beck, A. T., Epstein, N., Brown, G., & Steer, R. A. (1988) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.56.6.893 · Cited by 14,407
Everitt, B. S. (2001) · Psychology Press eBooks · doi:10.4324/9781410605542-11 · Cited by 6,877
Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease
Kris-Etherton, P. M., Harris, W. S., & Appel, L. J. (2002) · Circulation · doi:10.1161/01.cir.0000038493.65177.94 · Cited by 3,707
Cytokines sing the blues: inflammation and the pathogenesis of depression
Raison, C. L., Capuron, L., & Miller, A. H. (2006) · Trends in Immunology · doi:10.1016/j.it.2005.11.006 · Cited by 3,009
Origins and evolution of the Western diet: health implications for the 21st century1,2
Cordain, L., Eaton, S. B., Sebastian, A., Mann, N., Lindeberg, S., Watkins, B. A., O’Keefe, J. H., & Brand-Miller, J. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn.81.2.341 · Cited by 2,397
Stress-induced immune dysfunction: implications for health
Glaser, R., & Kiecolt-Glaser, J. K. (2005) · Nature Reviews Immunology · doi:10.1038/nri1571 · Cited by 2,190
Self-citation
Flagged first, then by citations
2 of the 70 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Maes, 1998, Fatty acids, cytokines, and major depression, Biol. Psychiatry, 43, 313
Cited by
Sorted by citations
Items 101–200 of 343
Fond, G. B., Bourbon, A., Boucékine, M., Messiaen, M., Barrow, V., Auquier, P., Lançon, C., & Boyer, L. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.01.035 · Cited by 30
Cannas, S., Tonini, B., Belà, B., Prinzio, R. D., Pignataro, G., Simone, D. D., & Gramenzi, A. (2020) · Journal of Veterinary Behavior · doi:10.1016/j.jveb.2020.09.002 · Cited by 35
Mental Health in Childhood and Adolescence: The Role of Polyunsaturated Fatty Acids
Bozzatello, P., Blua, C., Rocca, P., & Bellino, S. (2021) · Biomedicines · doi:10.3390/biomedicines9080850 · Cited by 30
The role of omega-3 on modulation of cognitive deficiency induced by REM sleep deprivation in rats
Nasehi, M., Mosavi-Nezhad, S.-M., Khakpai, F., & Zarrindast, M. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.06.002 · Cited by 30
Basso, M., Johnstone, N., Knytl, P., Nauta, A., Groeneveld, A., & Cohen Kadosh, K. (2022) · Nutrients · doi:10.3390/nu14030614 · Cited by 28
Arteaga, O., Revuelta, M., Urigüen, L., Martínez‐Millán, L., Hilario, E., & Alvarez, A. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0221-8 · Cited by 28
Role of Omega-3 PUFAs in Neurobiological Health
Grant, R., & Guest, J. (2016) · Advances in neurobiology · doi:10.1007/978-3-319-28383-8_13 · Cited by 28
Manos, B. E., Bravender, T. D., Harrison, T. M., Lange, H. L. H., Cottrill, C. B., Abdel‐Rasoul, M., & Bonny, A. E. (2018) · International Journal of Eating Disorders · doi:10.1002/eat.22964 · Cited by 27
Omega-3 fatty acids and anxiety: A systematic review of the possible mechanisms at play
Polokowski, A. R., Shakil, H., Carmichael, C. L., & Reigada, L. C. (2018) · Nutritional Neuroscience · doi:10.1080/1028415x.2018.1525092 · Cited by 26
Plasma sphingolipids and depressive symptoms in coronary artery disease
Dinoff, A., Saleem, M., Herrmann, N., Mielke, M. M., OH, P. I., Venkata, S. L. V., Haughey, N. J., & Lanctôt, K. L. (2017) · Brain and Behavior · doi:10.1002/brb3.836 · Cited by 27
Neuroendocrine Regulation of Anxiety: Beyond the Hypothalamic‐Pituitary‐Adrenal Axis
Borrow, A. P., Stranahan, A. M., Suchecki, D., & Yunes, R. (2016) · Journal of Neuroendocrinology · doi:10.1111/jne.12403 · Cited by 27
McDonnell, S. L., French, C., Baggerly, C. A., & Harris, W. S. (2019) · Nutrition Research · doi:10.1016/j.nutres.2019.09.001 · Cited by 27
Frankhouser, D. E., Steck, S., Sovic, M. G., Belury, M. A., Wang, Q., Clinton, S. K., Bundschuh, R. A., Yan, P. S., & Yee, L. D. (2021) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2021.108839 · Cited by 25
Self-citationNeto, J., Jantsch, J., de Oliveira, S., Braga, M. F., Castro, L. F. D. S., Diniz, B. F., Moreira, J. C. F., Giovenardi, M., Porawski, M., & Guedes, R. P. (2021) · British Journal Of Nutrition · doi:10.1017/s0007114521003998 · Cited by 26
Dietary supplements in neurological diseases and brain aging
Dhuli, K., Naureen, Z., Medori, M. C., Caruso, P., Manganotti, P., Chiurazzi, P., & Bertelli, M. (2022) · Journal of preventive medicine and hygiene · doi:10.15167/2421-4248/jpmh2022.63.2s3.2759 · Cited by 26
McNelly, A. S., Monti, M., GRIMBLE, G. K., Norton, C. S., Bredin, F., Czuber‐Dochan, W., Berliner, S., & Forbes, A. (2016) · Gastrointestinal Nursing · doi:10.12968/gasn.2016.14.8.39 · Cited by 26
The Role of Dietary Supplements in Depression and Anxiety – A Narrative Review
Hoffmann, K., Emons, B., Brunnhuber, S., Karaca, S., & Juckel, G. (2019) · Pharmacopsychiatry · doi:10.1055/a-0942-1875 · Cited by 26
Vors, C., Allaire, J., Mejía, S. B., Khan, T. A., Sievenpiper, J. L., & Lamarche, B. (2020) · Advances in Nutrition · doi:10.1093/advances/nmaa086 · Cited by 27
Wang, T., Niu, K., Fan, A., Bi, N., Tao, H., Chen, X.-T., & Wang, H.-L. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112545 · Cited by 24
Phase separation drives the formation of biomolecular condensates in the immune system
Wen, Y., & Ma, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.986589 · Cited by 24
Bafkar, N., Zeraattalab-Motlagh, S., Jayedi, A., & Shab‐Bidar, S. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-05881-2 · Cited by 24
Carlson, S. J., O’Loughlin, A. A., Anez-Bustillos, L., Baker, M. A., Andrews, N. A., Gunner, G., Dao, D. T., Pan, A., Nandivada, P., Chang, M., et al. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00072 · Cited by 24
Tong, J., Satyanarayanan, S. K., & Su, H. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.08.027 · Cited by 24
Guertin, M.-H., Robitaille, K., Pelletier, J.-F., Duchesne, T., Julien, P., Savard, J., Bairati, I., & Fradet, V. (2018) · BMC Cancer · doi:10.1186/s12885-017-3979-9 · Cited by 23
Dietary and botanical anxiolytics
Alramadhan, E., Hanna, M. S., Hanna, M. S., Goldstein, T. G., Avila, S. M., & Weeks, B. S. (2012) · Medical Science Monitor · doi:10.12659/msm.882608 · Cited by 23
Adverse Childhood Experiences among Veterinary Medical Students: A Multi-Site Study
Strand, E. B., Brandt, J., Rogers, K. S., Fonken, L., Chun, R., Conlon, P. D., & Lord, L. K. (2017) · Journal of Veterinary Medical Education · doi:10.3138/jvme.0816-123r · Cited by 22
Littrell, J. L. (2012) · Frontiers in Psychology · doi:10.3389/fpsyg.2012.00297 · Cited by 22
Serum docosahexaenoic acid (DHA) is inversely associated with anxiety disorders in early pregnancy
Verly-Miguel, M., Farias, D. R., Pinto, T., Lepsch, J., Nardi, A. E., & Kac, G. (2014) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2014.12.002 · Cited by 28
Rajabi‐Naeeni, M., Dolatian, M., Qorbani, M., & Vaezi, A. A. (2021) · Brain and Behavior · doi:10.1002/brb3.2342 · Cited by 21
Inflammasomes: Cause or consequence of obesity‐associated comorbidities in humans
Herrera-Martínez, A. D., Herrero‐Aguayo, V., Pérez‐Gómez, J. M., Gahete, M. D., & Luque, R. M. (2022) · Obesity · doi:10.1002/oby.23581 · Cited by 22
Test Anxiety Among US Medical Students: A Review of the Current Literature
Williamson, C., Wright, S. T., & Dallaghan, G. L. B. (2024) · Medical Science Educator · doi:10.1007/s40670-024-01999-w · Cited by 21
Khorsan, R., Crawford, C. C., Ives, J. A., Walter, A. R., & Jonas, W. B. (2014) · Military Medicine · doi:10.7205/milmed-d-14-00339 · Cited by 24
Wilson, P. B., & Madrigal, L. A. (2017) · Journal of the American College of Nutrition · doi:10.1080/07315724.2017.1335249 · Cited by 21
Effect of High Ratio of n-6/n-3 PUFAs on Depression: A Meta-Analysis of Prospective Studies
Wang, Y., Dong, L., Pan, D., Xu, D., Lu, Y., Yin, S., Wang, S., Xia, H., Liao, W., & Sun, G. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.889576 · Cited by 21
Yang, R., Wang, L., Jin, K., Cao, S., Wu, C., Guo, J., Chen, J., Tang, H., & Tang, M. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.876152 · Cited by 20
Patel, D., Evanchuk, J. L., Wang, R., Dunbar, C. L., Munhoz, J., & Field, C. J. (2023) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2022-0456 · Cited by 20
Decoeur, F., Benmamar‐Badel, A., Leyrolle, Q., Persillet, M., Layé, S., & Nadjar, A. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.05.016 · Cited by 21
Omega‐3 fatty acid in ultra‐high‐risk psychosis: A systematic review based on functional outcome
Susai, S. R., Sabherwal, S., Mongan, D., Föcking, M., & Cotter, D. R. (2022) · Early Intervention in Psychiatry · doi:10.1111/eip.13133 · Cited by 19
Associations between major dietary patterns and anxiety in middle-aged adults in eastern China
Xu, F., Chong, B.-Q., Cai, T., Zhang, J., & Lv, J. (2020) · Public Health Nutrition · doi:10.1017/s1368980020000221 · Cited by 19
Dogaru, I.-A., Puiu, M. G., Manea, M., & Dionisie, V. (2022) · Brain Sciences · doi:10.3390/brainsci12101403 · Cited by 20
Fish oil as a management component for mood disorders – an evolving signal
Hegarty, B. D., & Parker, G. B. (2012) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e32835ab4a7 · Cited by 19
Ginty, A. T., Muldoon, M. F., Kuan, D. C.-H., Schirda, B. L., Kamarck, T. W., Jennings, J. R., Manuck, S. B., & Gianaros, P. J. (2017) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000453 · Cited by 19
Diet quality and anxiety: a critical overview with focus on the gut microbiome
Basso, M., Zorzan, I., Johnstone, N., Barberis, M., & Kadosh, K. C. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1346483 · Cited by 19
Young, A., Marriott, B. P., Champagne, C. M., Hawes, M. R., Montain, S. J., Johannsen, N. M., Berry, K., & Hibbeln, J. R. (2017) · British Journal Of Nutrition · doi:10.1017/s0007114517001003 · Cited by 18
Norouziasl, R., Zeraattalab-Motlagh, S., Jayedi, A., & Shab‐Bidar, S. (2023) · British Journal Of Nutrition · doi:10.1017/s0007114523002052 · Cited by 18
Dhiman, A., Chopra, R., Singh, P. K., Homroy, S., Chand, M., & Talwar, B. (2023) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.13225 · Cited by 17
Xia, J., Chen, M., Shao, H., Chen, H., Zhu, S., Zhao, M., Luo, W., Yang, J., & Wu, S. (2023) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2812356 · Cited by 17
Krill oil: nutraceutical potential in skin health and disease
Duo, L., Yang, J., Wang, X., Zhang, G., Zhao, J., Zou, H., Wang, Z., & Li, Y. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1388155 · Cited by 17
Essential Fatty Acids as Potential Anti-Inflammatory Agents in the Treatment of Affective Disorders
Song, C. (2013) · Modern trends in psychiatry · doi:10.1159/000343970 · Cited by 17
Zhou, P., Wu, J., Wang, Y., Zhang, H., Xia, Y. Q., Zhang, Y., & Xu, S. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.12.125 · Cited by 17
Cavalli, J., Freitas, M. A., Gonçalves, E. C. D., Fadanni, G. P., Santos, A. A., Raposo, N. R. B., & Dutra, R. C. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110703 · Cited by 17
The Gut-Brain Axis and Mental Health: How Diet Shapes Our Cognitive and Emotional Well-Being
Patil, S., & Mehdi, S. S. (2025) · Cureus · doi:10.7759/cureus.88420 · Cited by 19
Reily, N. M., Tang, S., Negrone, A., Gan, D. Z. Q., Sheanoda, V., & Christensen, H. M. (2023) · PLoS ONE · doi:10.1371/journal.pone.0284057 · Cited by 17
Omega-3 Supplementation for Psychotic Mania and Comorbid Anxiety in Children
Vesco, A. T., Lehmann, J., Gracious, B., Arnold, L. E., Young, A. S., & Fristad, M. A. (2015) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2013.0141 · Cited by 17
Costa, A., Rani, B., Bastiaanssen, T. F. S., Bonfiglio, F., Gunnigle, E., Provensi, G., Rossitto, M., Boehme, M., Strain, C., Suárez-Martínez, C., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23020862 · Cited by 17
Siritientong, T., Thet, D., Buangbon, M., Nokehoon, P., Leelakanok, N., Methaneethorn, J., Angspatt, A., & Meevassana, J. (2022) · Nutrients · doi:10.3390/nu14142874 · Cited by 16
Delpino, F. M., & Figueiredo, L. M. (2022) · European Journal of Clinical Nutrition · doi:10.1038/s41430-022-01100-x · Cited by 15
Savard, J., Moussa, H., Pelletier, J., Julien, P., Lacombe, L., Tiguert, R., Caumartin, Y., Dujardin, T., Toren, P., Pouliot, F., et al. (2023) · Cancer Medicine · doi:10.1002/cam4.6598 · Cited by 15
The association between nutrition and behavioural health in a US Army population
Forys, K. L., Brooks, R. D., Beymer, M. R., & Pecko, J. A. (2020) · Public Health Nutrition · doi:10.1017/s1368980020001238 · Cited by 14
White, M. R., & Yates, D. T. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1250134 · Cited by 15
Ketogenic diet and cancer: multidimensional exploration and research
Wan, S., Zhou, X., Xie, F., Zhou, F., & Zhang, L. (2025) · Science China Life Sciences · doi:10.1007/s11427-023-2637-2 · Cited by 13
Berger, G. E. (2016) · Journal of Clinical Medicine · doi:10.3390/jcm5080069 · Cited by 13
Sabião, T. D. S., de Oliveira, F. C., Bressan, J., Pimenta, A. M., Hermsdorff, H. H. M., de Oliveira, F. L. P., Mendonça, R. D. D., & Carraro, J. C. C. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.11.012 · Cited by 13
Nagayasu, Y., Fujita, D., Daimon, A., Nunode, M., Sawada, M., Sano, T., & Ohmichi, M. (2021) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.14592 · Cited by 13
Antonini, R., Scaini, G., Michels, M., Matias, M. B. D., Schuck, P. F., Ferreira, G. C., de Oliveira, J., Dal‐Pizzol, F., & STRECK, E. L. (2019) · Metabolic Brain Disease · doi:10.1007/s11011-019-00525-x · Cited by 12
Lv, S., Dai, W., Zheng, Y., Dong, P., Yu, Y., Zhao, Y., Sun, S., Bi, D., Liu, C., Han, F., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.966218 · Cited by 12
Fish consumption patterns, knowledge and potential exposure to mercury by race
Lin, S., Herdt‐Losavio, M. L., Chen, M., Luo, M., Tang, J., & Hwang, S. (2013) · International Journal of Environmental Health Research · doi:10.1080/09603123.2013.818106 · Cited by 12
Are Mood and Anxiety Disorders Inflammatory Diseases?
Boorman, E., Romano, G. F., Russell, A., Mondelli, V., & Pariante, C. M. (2015) · Psychiatric Annals · doi:10.3928/00485713-20150501-06 · Cited by 13
Fourrier, C., Kropp, C., Aubert, A., Sauvant, J., Vaysse, C., Chardigny, J., Layé, S., Joffre, C., & Castanon, N. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.11.002 · Cited by 15
Kalinić, D., Štefanović, L. B., Jerončić, A., Mimica, N., Dodig, G., & Delaš, I. (2014) · PubMed · Cited by 12
Naidoo, U. (2020) · American Journal of Lifestyle Medicine · doi:10.1177/1559827620973936 · Cited by 11
Omega-3 fatty acid supplementation for depression in children and adolescents
Campisi, S. C., Zasowski, C., Bradley-Ridout, G., Schumacher, A., Szatmári, P., & Korczak, D. J. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd014803.pub2 · Cited by 12
Susai, S. R., Mongan, D., Healy, C., Cannon, M. D., Nelson, B., Markulev, C., Schäfer, M. R., Berger, M., Mossaheb, N., Schlögelhofer, M., et al. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.09.018 · Cited by 11
Xie, J., Li, Y., Liang, Y., Kui, H., Wang, C., & Huang, J. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116571 · Cited by 11
Nutrient insufficiencies and deficiencies involved in the pathogenesis of bruxism (Review)
Pavlou, I., Spandidos, D. A., Zoumpourlis, V. C., & Adamaki, M. (2023) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2023.12262 · Cited by 13
Integrative Therapies in Cancer
Block, K. I., Block, P. B., & Gyllenhaal, C. (2015) · Integrative Cancer Therapies · doi:10.1177/1534735414567473 · Cited by 11
Delpino, F. M., & Figueiredo, L. M. (2021) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2021.05.002 · Cited by 13
Shati, A. A., & El-kott, A. F. (2021) · Human & Experimental Toxicology · doi:10.1177/09603271211038739 · Cited by 12
Mohammed, S. G. A. A., & Qoronfleh, M. W. (2020) · Advances in neurobiology · doi:10.1007/978-3-030-30402-7_9 · Cited by 13
Cortes, M. L., Castro, M. M. C., de Jesús, R. P., Neto, J. A. D. B., & Kraychete, D. C. (2013) · Revista Dor · doi:10.1590/s1806-00132013000100012 · Cited by 11
Kamat, D., Al-Ajlouni, Y. A., & Hall, R. C. W. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20065171 · Cited by 10
Carvajal, F., Sánchez-Gil, A., Cardona, D., Rincón‐Cervera, M. Á., & Lerma-Cabrera, J. M. (2023) · Nutrients · doi:10.3390/nu15132993 · Cited by 11
The Influence of Diet and Physical Activity on Periodontal Health: A Narrative Review
Balice, G., Paolantonio, M., Murmura, G., Serroni, M., Gregorio, S. D., & Femminella, B. (2025) · Dentistry Journal · doi:10.3390/dj13050200 · Cited by 12
Comparative Analysis of the Antioxidant and Anti-Inflammatory Effects of Krill and Fish Oil
Sarıyer, E. T., Baş, M., & Yüksel, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157360 · Cited by 10
International Society of Stress ", Akarachkova, E. S., Control", S. U., M., Belyaev, A. A., Ринадовна, К. Л., Klimov, L. V., Котова, О. В., & International Society of Stress "Stress Under Control", M. (2021) · Russian Medical Inquiry · doi:10.32364/2587-6821-2021-5-5-316-321 · Cited by 10
L-Triptofano, ômega 3, magnésio e vitaminas do complexo B na diminuição dos sintomas de ansiedade
de Andrade, E. A. F., Sant´Anna, L. C., Almeida, N. D. C., Venturi, I., Brustulim, L. J. R., & D’Almeida, W. O. (2018) · ID on line REVISTA DE PSICOLOGIA · doi:10.14295/idonline.v12i40.1165 · Cited by 10
Jahan, I., Uddin, A. B. M. N., Reza, A. S. M. A., Uddin, M. G., Hossain, M. S., Nasrin, S., Emran, T. B., & Rahman, M. A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0249897 · Cited by 10
Sumich, A. L., Matsudaira, T., Heasman, B. C., Gow, R. V., Ibrahimovic, A., Ghebremeskel, K., Crawford, M. A., & Taylor, E. A. (2013) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2013.03.004 · Cited by 10
Shahamati, D., Akhavan, N. S., & Rosenkranz, S. K. (2025) · Biomolecules · doi:10.3390/biom15111516 · Cited by 11
From Dysbiosis to Distress: The Gut–Brain Connection in Trauma-Related Disorders
Marano, G., Giudice, L. L., Specogna, E., Chisari, L., Brisi, C., Traversi, G., Mazza, O., & Mazza, M. (2026) · Nutrients · doi:10.3390/nu18030530 · Cited by 9
Dietary Supplements Use among Serbian Undergraduate Students of Different Academic Fields
Vidović, B. B., Đuričić, B., Odalović, M., Georgiev, A. M., & Tadić, I. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191711036 · Cited by 9
Wang, Z., Yang, Y., Tang, F., & Wu, M. (2024) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2024.102615 · Cited by 9
Li, Z., Ren, W., Han, X., Liu, X., Wang, G., Zhang, M., Pang, D., Ouyang, H., & Tang, X. (2015) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500022 · Cited by 9
Effects of dietary interventions on telomere dynamics
Ng, G. Y.-Q., Hande, V., Ong, M. H., Wong, B. W.-X., Loh, Z. W.-L., Ho, W. D., Handison, L. B., Tan, I. M.-S. P., Fann, D. Y., Arumugam, T. V., et al. (2022) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2022.503472 · Cited by 11
Susai, S. R., Mongan, D., Healy, C., Cannon, M. D., Cagney, G., Wynne, K. J., Byrne, J. F., Markulev, C., Schäfer, M. R., Berger, M., et al. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.03.013 · Cited by 9
Dietary inflammatory index and neuropsychiatric disorders
Nasab, M. G., Heidari, A., Sedighi, M., Shakerian, N., Mirbeyk, M., Saghazadeh, A., & Rezaei, N. (2023) · Reviews in the Neurosciences · doi:10.1515/revneuro-2023-0047 · Cited by 9
Anxiolytic‐Like Actions of Fatty Acids Identified in Human Amniotic Fluid
García-Ríos, R. I., Rodríguez‐Landa, J. F., & Contreras, C. M. (2013) · The Scientific World JOURNAL · doi:10.1155/2013/823289 · Cited by 9
Polyunsaturated fatty acids moderate the effect of poor sleep on depression risk
Lotrich, F. E., Sears, B., & McNamara, R. K. (2015) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2015.10.004 · Cited by 9
Examining techniques for measuring the effects of nutrients on mental performance and mood state
Hamer, M., Dye, L., Mitchell, E. S., Layé, S., Saunders, C., Boyle, N., Schuermans, J., & Sijben, J. (2016) · European Journal of Nutrition · doi:10.1007/s00394-015-1143-3 · Cited by 11
Metadata
- Authors
- Kiecolt-Glaser, J. K., Belury, M. A., Andridge, R., Malarkey, W. B., & Glaser, R.
- Affiliations
- The Ohio State University (US)
- Venue
- Brain, Behavior, and Immunity
- Publisher
- Elsevier BV
- Published
- 2011-11
- Volume
- 25
- Issue
- 8
- Pages
- 1725-1734
- ISSN
- 0889-1591 (ISSN-L)
- PMC
- PMC3191260
- OpenAlex
- W2140758044
- Cited by
- 340
- References
- 70
- Citations by year
- 2026: 19 · 2025: 18 · 2024: 30 · 2023: 24 · 2022: 31 · 2021: 32 · 2020: 24 · 2019: 28 · 2018: 18 · 2017: 21 · 2016: 13 · 2015: 24 · 2014: 26 · 2013: 15 · 2012: 17
- FWCI
- 17.14
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Brain Behavior and Immunity (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Ohio State University
- National Institutes of Health (UL1TR000090)
- National Cancer Institute (CA16058, P30CA016058)
- National Center for Complementary and Alternative Medicine
- National Center for Research Resources (UL1RR025755)
- NIH Clinical Center
- National Center for Advancing Translational Sciences
- National Center for Complementary and Integrative Health (R21AT003912, AT003912)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Keywords
- omega-3 fatty acids, n-6/n-3 ratio, inflammation, anxiety, depression, medical students, eicosapentaenoic acid, docosahexaenoic acid, interleukin-6, TNF-α, lipopolysaccharide stimulation, exam stress, young adults
- MeSH terms
- Adult, Affect, Anxiety, Depression, Diet, Double-Blind Method, Fatty Acids, Female, Humans, Inflammation, Male, Neutrophils, Patient Compliance, Stress, Psychological, Health Behavior, Exercise, Fatty Acids, Omega-3, Cytokines, Sample Size, Dietary Supplements, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
