The competitive NMDA receptor antagonist CPP disrupts cocaine-induced conditioned place preference, but spares behavioral sensitization
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Recently, the notion that memory and addiction share similar neural substrates has become widely accepted. N-methyl-d-aspartate receptors (NMDAR) are the cornerstones of synaptic models of memory. The present study examined the effect of the competitive NMDAR antagonist CPP on the induction of behavioral sensitization and conditioned place preference to cocaine. Conditioned place preference is an associative memory model of drug seeking, while sensitization is a non-associative model of the transition from casual to compulsive use. There were three principal findings: (1) co-administration of CPP and cocaine altered the acute response to cocaine, suggesting a direct interaction between the two drugs; (2) NMDAR antagonism had no effect on behavioral sensitization; and (3) NMDAR antagonism abolished conditioned place preference. A review of prior evidence supporting a role for NMDARs in sensitization suggests that NMDAR antagonists directly interfere with cocaine's psychostimulant effects, and this interaction could be misinterpreted as a disruption of sensitization. Finally, we suggest that addiction recruits multiple kinds of plasticity, with sensitization recruiting NMDAR-independent mechanisms.
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The results support an interactionist view of memory and addiction.
“Our results tend to support an interactionist view of memory and addiction (Volkow et al., 2002; Carmack et al., 2013).”
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Cites
The neural basis of drug craving: An incentive-sensitization theory of addiction
Robinson, T. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90013-p · Cited by 7,346 · see citing works
Koob, G. F., & Volkow, N. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.110 · Cited by 5,340 · see citing works
Morris, R. G. M., Anderson, E., Lynch, G. S., & Baudry, M. (1986) · Nature · doi:10.1038/319774a0 · Cited by 3,640 · see citing works
The pharmacological basis of therapeutics
Frank, A. L. (1981) · Environmental Research · doi:10.1016/0013-9351(81)90176-6 · Cited by 2,738 · see citing works
Drug Dependence, a Chronic Medical Illness
McLellan, A. T., Lewis, D. C., O'Brien, C. P., & Kleber, H. D. (2000) · JAMA · doi:10.1001/jama.284.13.1689 · Cited by 2,622 · cited 1× · see citing works
“Indeed, although rehailitation clinics have become quite successful in detoxing patients nd sustaining abstinence for a few weeks or months, relapse ates remain very high [3].”
Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms
Citri, A., & Malenka, R. C. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301559 · Cited by 2,323 · see citing works
The incentive sensitization theory of addiction: some current issues
Robinson, T. E., & Berridge, K. C. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0093 · Cited by 1,717 · see citing works
Robinson, T. E., & Berridge, K. C. (2003) · Annual Review of Psychology · doi:10.1146/annurev.psych.54.101601.145237 · Cited by 1,509 · see citing works
[Drug addiction and drug abuse].
Feuerlein, W. (1969) · PubMed · Cited by 1,415 · see citing works
Conditional and unconditional components of post-shock freezing
Fanselow, M. S. (1980) · Pavlovian Journal of Biological Science · doi:10.1007/bf03001163 · Cited by 1,153 · see citing works
Addiction: A Disease of Learning and Memory
Hyman, S. E. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.8.1414 · Cited by 980 · see citing works
Mayer, M. L., & Westbrook, G. L. (1987) · The Journal of Physiology · doi:10.1113/jphysiol.1987.sp016883 · Cited by 935 · see citing works
The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants
Wolf, M. E. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00090-7 · Cited by 934 · see citing works
Kelley, A. E. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.016 · Cited by 773 · see citing works
Thomas, M. J., Beurrier, C., Bonci, A., & Malenka, R. C. (2001) · Nature Neuroscience · doi:10.1038/nn757 · Cited by 629 · see citing works
Harris, E. W., & Cotman, C. W. (1986) · Neuroscience Letters · doi:10.1016/0304-3940(86)90451-9 · Cited by 540 · see citing works
Neuroadaptations involved in amphetamine and cocaine addiction
White, F. J., & Kalivas, P. W. (1998) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(98)00072-6 · Cited by 509 · see citing works
Blockade of “reverse tolerance” to cocaine and amphetamine by MK-801
Karler, R., Calder, L. I., Chaudhry, I. A., & Turkanis, S. A. (1989) · Life Sciences · doi:10.1016/0024-3205(89)90045-3 · Cited by 488 · see citing works
The pharmacological basis of therapeutics. 6th ed
Atkinson, A. J., & Littman, A. (1981) · Gastroenterology · doi:10.1016/0016-5085(81)90293-6 · Cited by 466 · see citing works
Drug Addiction and the Memory Systems of the Brain
Robbins, T. W., Ersche, K. D., & Everitt, B. J. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1441.020 · Cited by 447 · see citing works
Molecular Neurobiology of Addiction
Nestler, E. J. (2001) · American Journal on Addictions · doi:10.1080/105504901750532094 · Cited by 412 · see citing works
Maren, S., Aharonov, G., Stote, D. L., & Fanselow, M. S. (1996) · Behavioral Neuroscience · doi:10.1037//0735-7044.110.6.1365 · Cited by 372 · see citing works
Kalivas, P. W., & Alesdatter, J. E. (1993) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)39530-3 · Cited by 368 · see citing works
Maren, S., Aharonov, G., Stote, D. L., & Fanselow, M. S. (1996) · Behavioral Neuroscience · doi:10.1037/0735-7044.110.6.1365 · Cited by 325 · see citing works
Anagnostaras, S., & Robinson, T. E. (1996) · Behavioral Neuroscience · doi:10.1037//0735-7044.110.6.1397 · Cited by 302 · see citing works
Self-citationAnagnostaras, S. G., & Robinson, T. E. (1996) · Behavioral Neuroscience · doi:10.1037/0735-7044.110.6.1397 · Cited by 302 · see citing works
Self-citationWolf, M. E., Dahlin, S. L., Hu, X., Xue, C., & White, K. (1995) · Neuroscience · doi:10.1016/0306-4522(95)00248-h · Cited by 261 · see citing works
Wolf, M. E., & Jeziorski, M. C. (1993) · Brain Research · doi:10.1016/0006-8993(93)90913-8 · Cited by 243 · see citing works
Cervo, L., & SAMANIN, R. (1995) · Brain Research · doi:10.1016/0006-8993(94)01420-m · Cited by 239 · see citing works
Wolf, M. E., & Khansa, M. R. (1991) · Brain Research · doi:10.1016/0006-8993(91)91202-c · Cited by 237 · see citing works
Lehmann, J. C., Schneider, J. A., McPherson, S. E., Murphy, D. E., Bernard, P. S., Tsai, C., Bennett, D. A., Pastor, G., Steel, D. J., & Boehm, C. (1987) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-5347(25)00366-0 · Cited by 237 · see citing works
Mechanisms of Locomotor Sensitization to Drugs of Abuse in a Two-Injection Protocol
Valjent, E., Bertran‐Gonzalez, J., Aubier, B., Greengard, P., Hervé, D., & Girault, J. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.143 · Cited by 206 · see citing works
(+)-MK-801 induced social withdrawal in rats; a model for negative symptoms of schizophrenia
Rung, J. P., Carlsson, A., Markinhuhta, K. R., & Carlsson, M. L. (2005) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2005.03.004 · Cited by 200 · see citing works
Li, Y., Hu, X., Berney, T. G., Vartanian, A. J., Stine, C. D., Wolf, M. E., & White, F. J. (1999) · Synapse · doi:10.1002/(sici)1098-2396(19991201)34:3 · Cited by 182 · see citing works
Stewart, J., & Druhan, J. P. (1993) · Psychopharmacology · doi:10.1007/bf02246961 · Cited by 179 · see citing works
Anagnostaras, S. G. (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2010.00158 · Cited by 169 · see citing works
Self-citationDNQX blockade of amphetamine behavioral sensitization
Karler, R., Calder, L. D., & Turkanis, S. A. (1991) · Brain Research · doi:10.1016/0006-8993(91)90095-d · Cited by 168 · see citing works
Computer-Assisted Behavioral Assessment of Pavlovian Fear Conditioning in MicePreprint
Anagnostaras, S., Josselyn, S. A., Frankland, P. W., & Silva, A. J. (2000) · Learning & Memory · doi:10.1101/lm.7.1.58 · Cited by 165 · see citing works
Self-citationCritical Role for Ventral Tegmental Glutamate in Preference for a Cocaine-Conditioned Environment
Harris, G. C., & Aston‐Jones, G. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300011 · Cited by 163 · see citing works
Cador, M., Bjijou, Y., Cailhol, S., & Stinus, L. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00361-9 · Cited by 157 · see citing works
Schilström, B., Yaka, R., Argilli, E., Suvarna, N. U., Schumann, J., Chen, B. T., Carman, M., Singh, V., Mailliard, W. S., Dorit Ron, A., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.5179-05.2006 · Cited by 147 · see citing works
Memory processes governing amphetamine-induced psychomotor sensitization
Anagnostaras, S. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00402-x · Cited by 143 · see citing works
Self-citationL-name and MK-801 attenuate sensitization to the locomotor-stimulating effect of cocaine
Pudiak, C. M., & Bozarth, M. A. (1993) · Life Sciences · doi:10.1016/0024-3205(93)90559-l · Cited by 134 · see citing works
Dopamine Receptor Antagonists Fail to Prevent Induction of Cocaine Sensitization
White, F. (1998) · Neuropsychopharmacology · doi:10.1016/s0893-133x(97)00093-6 · Cited by 121 · see citing works
Cocaine behavioral sensitization and the excitatory amino acids
Karler, R., Calder, L. D., & Bedingfield, J. B. (1994) · Psychopharmacology · doi:10.1007/bf02245070 · Cited by 118 · see citing works
Hippocampal mossy fiber LTP is independent of postsynaptic calcium
Mellor, J. R., & Nicoll, R. A. (2001) · Nature Neuroscience · doi:10.1038/83941 · Cited by 113 · see citing works
[3H]CPP, a new competitive ligand for NMDA receptors
Olverman, H. J., Monaghan, D. T., Cotman, C. W., & Watkins, J. C. (1986) · European Journal of Pharmacology · doi:10.1016/0014-2999(86)90533-9 · Cited by 108 · see citing works
Inducible, pharmacogenetic approaches to the study of learning and memory
Ohno, M., Frankland, P. W., Chen, A. P., Costa, R. M., & Silva, A. J. (2001) · Nature Neuroscience · doi:10.1038/nn771 · Cited by 107 · see citing works
Competitive and noncompetitive NMDA antagonists block sensitization to methamphetamine
Ohmori, T., Abekawa, T., Muraki, A., & Koyama, T. (1994) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(94)90318-2 · Cited by 101 · see citing works
Neuronal death after brain injury
Kermer, P., Klöcker, N., & Bähr, M. (1999) · Cell and Tissue Research · doi:10.1007/s004410050061 · Cited by 95 · see citing works
Vezina, P., & Queen, A. L. (2000) · Psychopharmacology · doi:10.1007/s002130000463 · Cited by 88 · see citing works
Kim, H.-S., Park, W.-K., Jang, C., & Oh, S. (1996) · Brain Research Bulletin · doi:10.1016/0361-9230(96)00006-8 · Cited by 82 · see citing works
Papp, M. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00349-4 · Cited by 78 · see citing works
Itzhak, Y., & Stein, I. D. (1992) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)10781-7 · Cited by 71 · see citing works
Excitatory amino acids and the actions of cocaine
Karler, R., & Calder, L. D. (1992) · Brain Research · doi:10.1016/0006-8993(92)90329-8 · Cited by 69 · see citing works
Cocaine binds to a common site on open and inactivated human heart (Nav1.5) sodium channels
O’Leary, M. E., & Chahine, M. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2001.016139 · Cited by 64 · see citing works
Maldonado, C., Rodríguez‐Arias, M., Castillo, A., Aguilar, M. A., & Miñarro, J. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.02.012 · Cited by 63 · see citing works
The role of the frontal cortex in the mouse in behavioral sensitization to amphetamine
Karler, R., Bedingfield, J. B., Thai, D. K., & Calder, L. D. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00221-7 · Cited by 60 · see citing works
Licata, S. C., Schmidt, H. D., & Pierce, R. C. (2004) · European Journal of Neuroscience · doi:10.1111/j.0953-816x.2003.03110.x · Cited by 57 · see citing works
Segal, D. S., Kuczenski, R. T., & Florin, S. M. (1995) · Behavioral Neuroscience · doi:10.1037//0735-7044.109.3.532 · Cited by 53 · see citing works
Hrabětová, S., & Sacktor, T. C. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00252-8 · Cited by 50 · see citing works
The Role of the Striatum in the Mouse in Behavioral Sensitization to Amphetamine
Bedingfield, J. B. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(96)00331-0 · Cited by 50 · see citing works
Hoffman, D. C. (1994) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(94)90295-x · Cited by 49 · see citing works
Nitric oxide synthase inhibitors block behavioral sensitization to methamphetamine in mice
Ohno, M., & Watanabe, S. (1995) · European Journal of Pharmacology · doi:10.1016/0014-2999(94)00742-p · Cited by 49 · see citing works
Tzschentke, T., & Schmidt, W. (1998) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(98)01255-3 · Cited by 48 · see citing works
Kim, H.-S., & Jang, C. (1997) · Brain Research Bulletin · doi:10.1016/s0361-9230(97)00093-2 · Cited by 48 · see citing works
The NMDA receptor and cocaine: Evidence that MK-801 can induce behavioral sensitization effects
Carey, R. J., Dai, H., Krost, M., & Huston, J. P. (1995) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(95)00074-7 · Cited by 48 · see citing works
George, J., Dravid, S. M., Prakash, A., Xie, J., Peterson, J., Jabba, S. V., Baden, D. G., & Murray, T. F. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.6104-08.2009 · Cited by 46 · see citing works
NMDA receptor inhibition prevents tolerance to cocaine
Montis, M. G. D., Devoto, P., Meloni, D., Gambarana, C., Giorgi, G., & Tagliamonte, A. (1992) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(92)90463-p · Cited by 44 · see citing works
Wood, S. C., & Anagnostaras, S. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1185-9 · Cited by 44 · see citing works
Self-citationMemantine and ACPC affect conditioned place preference induced by cocaine in rats.
Kotlinska, J. H., & Biała, G. (2001) · PubMed · Cited by 42 · see citing works
Segal, D. S., Kuczenski, R. T., & Florin, S. M. (1995) · Behavioral Neuroscience · doi:10.1037/0735-7044.109.3.532 · Cited by 41 · see citing works
Ida, I., Asami, T., & Kuribara, H. (1995) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.69.83 · Cited by 40 · see citing works
Li, Y., & Wolf, M. E. (1999) · Psychopharmacology · doi:10.1007/s002130050844 · Cited by 39 · see citing works
Haracz, J. L., Belanger, S. A., MacDonall, J. S., & Sircar, R. (1995) · Life Sciences · doi:10.1016/0024-3205(95)02229-c · Cited by 39 · see citing works
Battisti, J. J., Shreffler, C. B., Uretsky, N. J., & Wallace, L. J. (2000) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(00)00324-5 · Cited by 38 · see citing works
The role of MK-801 in sensitization to stimulants
Sripada, S., Gaytan, O., Swann, A. C., & Dafny, N. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(00)00046-1 · Cited by 37 · see citing works
Druhan, J. P., & Wilent, W. B. (1999) · Behavioural Brain Research · doi:10.1016/s0166-4328(99)00017-0 · Cited by 34 · see citing works
Itzhak, Y., & Martin, J. L. (2000) · Neuropharmacology · doi:10.1016/s0028-3908(99)00073-8 · Cited by 32 · see citing works
Amphetamine and extinction of cued fear
Carmack, S. A., Wood, S. C., & Anagnostaras, S. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.10.049 · Cited by 27 · see citing works
Self-citationModulation of the PCP/NMDA receptor complex and sigma binding sites by psychostimulants
Itzhak, Y. (1994) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(94)90024-8 · Cited by 27 · see citing works
Panos, J., Rademacher, D. J., Renner, S. L., & Steinpreis, R. E. (1999) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(99)00155-0 · Cited by 27 · see citing works
Interdependence of measures in Pavlovian conditioned freezing
Wood, S. C., & Anagnostaras, S. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.10.006 · Cited by 27 · see citing works
Self-citationKotlinska, J. H., & Biała, G. (1999) · PubMed · Cited by 26 · see citing works
Ranaldi, R., Munn, E. M., Neklesa, T. K., & Wise, R. A. (2000) · Psychopharmacology · doi:10.1007/s002130000480 · Cited by 25 · see citing works
Blockade of behavioral sensitization by MK-801: fact or artifact?
Tzschentke, T., & Schmidt, W. (2000) · Psychopharmacology · doi:10.1007/s002130000395 · Cited by 23 · see citing works
Fix, A. S., Horn, J. W., Truex, L. L., Smith, R. A., & Gomez, E. (1994) · Acta Neuropathologica · doi:10.1007/bf00296487 · Cited by 19 · see citing works
Tolliver, B. K., Ho, L. B., Reid, M. S., & Berger, S. P. (1996) · Psychopharmacology · doi:10.1007/bf02246448 · Cited by 18 · see citing works
NMDA receptors and behavioural sensitization: beyond dizocilpine
Wolf, M. E. (1999) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(99)01356-5 · Cited by 17 · see citing works
Battisti, J. J., Uretsky, N. J., & Wallace, L. J. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00227-8 · Cited by 15 · see citing works
Richard, M. G., & Bennett, J. P. (1994) · Experimental Neurology · doi:10.1006/exnr.1994.1146 · Cited by 14 · see citing works
Song, G., Tin, C., Giacometti, E., & Poon, C. (2011) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2011.00006 · Cited by 13 · see citing works
Confused about NMDA and Addiction? Targeted Knockouts Provide Answers and New Questions
Carr, D. B., & Kalivas, P. W. (2008) · Neuron · doi:10.1016/j.neuron.2008.07.025 · Cited by 10 · see citing works
Decreased Accumbens Dopamine Release After Cocaine Challenge in Behaviorally Sensitized Female Rats
Johnson, D. W., Eodice, P., Winterbottom, H., & Mokler, D. J. (2000) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(99)00257-9 · Cited by 8 · see citing works
Grönig, M., Atalla, A., & Kuschinsky, K. (2006) · Pharmacology · doi:10.1159/000094413 · Cited by 5 · see citing works
Tzschentke, T., & Schmidt, W. (1999) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(99)01317-6 · Cited by 3 · see citing works
The dopamine antagonist Sch 23390 reverses dizocilpine-induced blockade of cocaine sensitization
Parada, A., & Soares-da-Silva, P. (2000) · Neuropharmacology · doi:10.1016/s0028-3908(99)00238-5 · Cited by 3 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- [9]9. Robinson TE, Berridge KC. Addiction. Annual Review of Psychology 2003;54:25-53.
- [65]65. Fanselow MS. Conditioned and unconditional components of post-shock freez- ing. Pavlovian Journal of Biological Science 1980;15:177-82.
Cited by
Sorted by citations
The learning of fear extinction
Furini, C., Myskiw, J., & Izquierdo, I. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.10.016 · Cited by 124 · see citing works
HDAC3 Is a Negative Regulator of Cocaine-Context-Associated Memory Formation
Rogge, G. A., Singh, H., Dang, R., & Wood, M. A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.4472-12.2013 · Cited by 124 · see citing works
Egunlusi, A. O., & Joubert, J. (2024) · Pharmaceuticals · doi:10.3390/ph17050639 · Cited by 101 · see citing works
Do specific NMDA receptor subunits act as gateways for addictive behaviors?
Hopf, F. W. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12348 · Cited by 63 · see citing works
Tu, G., Li, Y., Ye, L., Zhao, J., Liu, N., Li, J., Liu, Y., Zhu, M., Wu, Y. H., Xiao, B., et al. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.03.966 · Cited by 55 · see citing works
Animal model of methylphenidate's long-term memory-enhancing effectsPreprint
Carmack, S., Howell, K. K., Rasaei, K., Reas, E. T., & Anagnostaras, S. (2014) · Learning & Memory · doi:10.1101/lm.033613.113 · Cited by 37 · see citing works
Self-citationMDMA and memory, addiction, and depression: dose-effect analysis
Pantoni, M. M., Kim, J. L., Alstyne, K. R. V., & Anagnostaras, S. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06086-9 · Cited by 36 · see citing works
Self-citationIman, I. N., Yusof, N. A. M., Talib, U. N., Ahmad, N. A. Z., Norazit, A., Kumar, J., Mehat, M. Z., Jayabalan, N., Muthuraju, S., Stefaniuk, M., et al. (2021) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2021.683780 · Cited by 31 · see citing works
Yates, J. R. (2023) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2023.1256764 · Cited by 22 · see citing works
Implication of NMDA receptors in behavioural sensitization to psychostimulants: A short review
Landa, L., Máchalová, A., & Šulcová, A. (2014) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.02.028 · Cited by 22 · see citing works
Inhibition of PKC disrupts addiction-related memory
Howell, K., Monk, B., Carmack, S. A., Mrowczynski, O., Clark, R. E., & Anagnostaras, S. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00070 · Cited by 19 · see citing works
Self-citationShelkar, G. P., Gandhi, P. J., Liu, J., & Dravid, S. M. (2022) · Science Advances · doi:10.1126/sciadv.abo6574 · Cited by 18 · see citing works
Duart-Castells, L., López‐Arnau, R., Vizcaíno, S., Camarasa, J., Pubill, D., & Escubedo, E. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.02.004 · Cited by 13 · see citing works
Dopamine and norepinephrine transporter inhibition for long-term fear memory enhancement
Pantoni, M. M., Carmack, S. A., Hammam, L., & Anagnostaras, S. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112266 · Cited by 13 · see citing works
Self-citationLearning and Memory in Addiction
Carmack, S. A., Koob, G. F., & Anagnostaras, S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.21101-2 · Cited by 11 · see citing works
Self-citationFuture Perspectives of NMDAR in CNS Disorders
Capó, T., Rebassa, J. B., Raïch, I., Lillo, J., Badia, P., Navarro, G., & Reyes‐Resina, I. (2025) · Molecules · doi:10.3390/molecules30040877 · Cited by 10 · see citing works
Ruan, H., Sun, J., Liu, X., Liu, L., Cui, R., & Li, X. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.12.009 · Cited by 10 · see citing works
Li, L., Qiao, C., Chen, G., Qian, H., Hou, Y., Li, T., & Liu, X. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.08.022 · Cited by 10 · see citing works
Gill, K. E., Reynolds, A. R., Prendergast, M., & Akins, C. K. (2016) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000070 · Cited by 8 · see citing works
Proteasome phosphorylation regulates cocaine-induced sensitization
Gonzales, F. R., Howell, K. K., Dozier, L. E., Anagnostaras, S. G., & Patrick, G. N. (2018) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2017.12.001 · Cited by 7 · see citing works
Self-citationLiu, X., Tian, L., Cui, R., Ruan, H., & Li, X. (2017) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2017.11.039 · Cited by 6 · see citing works
Gemperline, E., Laha, K. T., Scarlett, C. O., Pearce, R. A., & Li, L. (2014) · Analytical Methods · doi:10.1039/c4ay01168f · Cited by 6 · see citing works
Phillips, T. J., Eastwood, E., & Harkness, J. H. (2014) · Cambridge University Press eBooks · doi:10.1017/cbo9781107360556.027 · Cited by 2 · see citing works
Quartarone, S. E. (2014) · QSpace (Queen's University Library)
Substance dependence and abuse
Pietropaolo, S., Sluyter, F., & Crusio, W. E. (2014) · Cambridge University Press eBooks · doi:10.1017/cbo9781107360556.024
Rusu-Zota, G., Trofin, D., Galeş, C., & Porumb‐Andrese, E. (2025) · Applied Sciences · doi:10.3390/app15158437
Andrianarivelo, A. (2020) · theses.fr (ABES) · doi:10.70675/1eda447azd2ecz4675zbc7azd4baf9a480db
Gill, K. E. (2015) · UKnowledge (University of Kentucky)
- Authors
- Carmack, S. A., Kim, J. S., Sage, J. R., Thomas, A. W., Skillicorn, K. N., & Anagnostaras, S. G.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Anagnostaras, Stephan G.
- Venue
- Behavioural Brain Research
- Publisher
- Elsevier BV
- Published
- 2013-02
- Volume
- 239
- Pages
- 155-163
- ISSN
- 0166-4328 (ISSN-L)
- OpenAlex
- W2103282170
- Cited by
- 29
- References
- 97
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 1 · 2017: 3 · 2016: 3 · 2015: 1 · 2014: 8 · 2013: 1
- FWCI
- 1.32
- Type
- journal article
- Language
- en
- Open access
- green
- escholarship.org
- Locations
- Behavioural Brain Research (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute on Drug Abuse (DA020041, R01DA020041)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- NMDA receptor antagonists, CPP, cocaine, conditioned place preference, behavioral sensitization, drug addiction, synaptic plasticity, drug-seeking behavior, psychostimulant effects
- MeSH terms
- Central Nervous System Stimulants, Animals, Cocaine, Conditioning, Psychological, Drug Interactions, Female, Male, Mice, Inbred C57BL, Motor Activity, Piperazines, Receptors, N-Methyl-D-Aspartate, Excitatory Amino Acid Antagonists, Mice, Central Nervous System Sensitization
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