Extracellular matrix alterations in brains lacking four of its components

Consequences of lack of beta 1 integrin gene expression in mice.Preprint

Fässler, R., & Meyer, M. (1995) · Genes & Development · doi:10.1101/gad.9.15.1896 · Cited by 733 · see citing works

Lecticans: organizers of the brain extracellular matrix

Yamaguchi, Y. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000690 · Cited by 642 · see citing works

Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion

Bellail, A. C., HUNTER, S. B., Brat, D. J., Tan, C., & Meir, E. G. V. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2004.01.013 · Cited by 527 · see citing works

Fibulins: a versatile family of extracellular matrix proteins

Timpl, R., Sasaki, T., Kostka, G., & Chu, M.-L. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1130 · Cited by 494 · see citing works

Brain extracellular matrix

Ruoslahti, E. (1996) · Glycobiology · doi:10.1093/glycob/6.5.489 · Cited by 467 · see citing works

Aggrecan Glycoforms Contribute to the Molecular Heterogeneity of Perineuronal Nets

Matthews, R. T., Kelly, G. M., Zerillo, C. A., Gray, G., Tiemeyer, M., & Hockfield, S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-17-07536.2002 · Cited by 341 · see citing works

TheCspg2Gene, Disrupted in thehdfMutant, Is Required for Right Cardiac Chamber and Endocardial Cushion Formation

Mjaatvedt, C. H., Yamamura, H., Capehart, A. A., Turner, D., & Markwald, R. R. (1998) · Developmental Biology · doi:10.1006/dbio.1998.9001 · Cited by 321 · see citing works

Chondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS?

Rhodes, K. E., & Fawcett, J. W. (2003) · Journal of Anatomy · doi:10.1111/j.1469-7580.2004.00261.x · Cited by 296 · see citing works

The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein– protein interactions independent of carbohydrate moiety

Aspberg, A., Miura, R., Bourdoulous, S., Shimonaka, M., Heinegård, D., Schachner, M., Ruoslahti, E., & Yamaguchi, Y. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.19.10116 · Cited by 275 · see citing works

Isolation and characterization of developmentally regulated chondroitin sulfate and chondroitin/keratan sulfate proteoglycans of brain identified with monoclonal antibodies

Rauch, U., Gao, P., Janetzko, A., Flaccus, A., Hilgenberg, L., Tekotte, H., Margolis, R. K., & Margolis, R. U. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)98755-7 · Cited by 267 · see citing works

Brevican-Deficient Mice Display Impaired Hippocampal CA1 Long-Term Potentiation but Show No Obvious Deficits in Learning and Memory

Brakebusch, C., Seidenbecher, C. I., Asztely, F., Rauch, U., Matthies, H., Meyer, H., Krug, M., Böckers, T. M., Zhou, X., Kreutz, M. R., et al. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.21.7417-7427.2002 · Cited by 264 · see citing works

Glycosaminoglycans of brain during development

Margolis, R. U., Margolis, R. K., Chang, L. B., & Preti, C. (1975) · Biochemistry · doi:10.1021/bi00672a014 · Cited by 250 · see citing works

Mice Deficient for Tenascin-R Display Alterations of the Extracellular Matrix and Decreased Axonal Conduction Velocities in the CNS

Weber, P., Bartsch, U., Rasband, M. N., Czaniera, R., Lang, Y., Bluethmann, H., Margolis, R. U., Levinson, S. R., Shrager, P., Montag, D., et al. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-11-04245.1999 · Cited by 247 · see citing works

Mouse cartilage matrix deficiency (cmd) caused by a 7 bp deletion in the aggrecan gene

Watanabe, H., Kimata, K., Line, S. R. P., Strong, D., Gao, L., Kozak, C. A., & Yamada, Y. (1994) · Nature Genetics · doi:10.1038/ng0694-154 · Cited by 245 · see citing works

Skin wounds and severed nerves heal normally in mice lacking tenascin-C.

Forsberg, E., Hirsch, E., Fröhlich, L., Meyer, M., Ekblom, P., Aszódi, A., Werner, S., & Fässler, R. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.13.6594 · Cited by 235 · see citing works

Differential regulation of expression of hyaluronan-binding proteoglycans in developing brain: aggrecan, versican, neurocan, and brevican.

Milev, P., Maurel, P., Chiba, A., Mevissen, M., Popp, S., Yamaguchi, Y., Margolis, R. K., & Margolis, R. U. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.8759 · Cited by 219 · see citing works

Fibulin-1 Is a Ligand for the C-type Lectin Domains of Aggrecan and Versican

Aspberg, A., Adam, S., Kostka, G., Timpl, R., & Heinegård, D. K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.29.20444 · Cited by 207 · see citing works

Neurocan Is Dispensable for Brain Development

Zhou, X.-H., Brakebusch, C., Matthies, H., Oohashi, T., Hirsch, E., Moser, M., Krug, M., Seidenbecher, C. I., Boeckers, T. M., Rauch, U., et al. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.17.5970-5978.2001 · Cited by 206 · see citing works

Extracellular matrix components associated with remodeling processes in brain

Rauch, U. (2004) · Cellular and Molecular Life Sciences (CMLS) · doi:10.1007/s00018-004-4043-x · Cited by 205 · see citing works

The Proteoglycans Aggrecan and Versican Form Networks with Fibulin-2 through Their Lectin Domain Binding

Olin, A. I., Mörgelin, M., Sasaki, T., Timpl, R., Heinegård, D. K., & Aspberg, A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m006783200 · Cited by 204 · see citing works

A Hyaluronan Binding Link Protein Gene Family Whose Members Are Physically Linked Adjacent to Chrondroitin Sulfate Proteoglycan Core Protein Genes

Spicer, A. P., Joo, A., & Bowling, R. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m213100200 · Cited by 201 · see citing works

The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study.

Roark, E. F., Keene, D. R., Haudenschild, C. C., Godyna, S., Little, C. D., & Argraves, W. S. (1995) · Journal of Histochemistry & Cytochemistry · doi:10.1177/43.4.7534784 · Cited by 193 · see citing works

Proteoglycans of basement membranes

Timpl, R. (1993) · Cellular and Molecular Life Sciences · doi:10.1007/bf01923586 · Cited by 172 · see citing works

Perinatal Lethality and Endothelial Cell Abnormalities in Several Vessel Compartments of Fibulin-1-Deficient Mice

Kostka, G., Giltay, R., Bloch, W., Addicks, K., Timpl, R., Fässler, R., & Chu, M. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.20.7025-7034.2001 · Cited by 168 · see citing works

Tenascin variants: differential binding to fibronectin and distinct distribution in cell cultures and tissues.

Chiquet‐Ehrismann, R., Matsuoka, Y., Hofer, U., Spring, J., Bernasconi, C., & Chiquet, M. (1991) · Cell Regulation · doi:10.1091/mbc.2.11.927 · Cited by 160 · see citing works

Distinct interaction of versican/PG-M with hyaluronan and link protein

Matsumoto, K., Shionyu, M., Go, M., Shimizu, K., Shinomura, T., Kimata, K., & Watanabe, H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305060200 · Cited by 153 · see citing works

Functional mapping of cytotactin: proteolytic fragments active in cell-substrate adhesion.

Friedlander, D. R., Hoffman, S., & Edelman, G. M. (1988) · The Journal of Cell Biology · doi:10.1083/jcb.107.6.2329 · Cited by 149 · see citing works

Neurocan: a brain chondroitin sulfate proteoglycan

Rauch, U., Feng, K., & Zhou, X.-H. (2001) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000822 · Cited by 136 · see citing works

Structural Basis for Interactions between Tenascins and Lectican C-Type Lectin Domains

Lundell, A., Olin, A. I., Mörgelin, M., al-Karadaghi, S., Aspberg, A., & Logan, D. T. (2004) · Structure · doi:10.1016/j.str.2004.05.021 · Cited by 127 · see citing works

Alternative splicing in the aggrecan G3 domain influences binding interactions with tenascin-C and other extracellular matrix proteins.

Day, J. M., Olin, A. I., Murdoch, A. D., Canfield, A., Sasaki, T., Timpl, R., Hardingham, T. E., & Aspberg, A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400242200 · Cited by 127 · see citing works

Versican V2 Is a Major Extracellular Matrix Component of the Mature Bovine Brain

Schmalfeldt, M., Dours-Zimmermann, M. T., Winterhalter, K. H., & Zimmermann, D. R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.25.15758 · Cited by 118 · see citing works

Region and lamina-specific distribution of extracellular matrix proteoglycans, hyaluronan and tenascin-R in the mouse hippocampal formation

Brückner, G., Grosche, J., Hartlage‐Rübsamen, M., Schmidt, S., & Schachner, M. (2003) · Journal of Chemical Neuroanatomy · doi:10.1016/s0891-0618(03)00036-x · Cited by 116 · see citing works

Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets☆

Bekku, Y., Su, W.-D., Hirakawa, S., Fässler, R., Ohtsuka, A., Kang, J. S., Sanders, J., Murakami, T., Ninomiya, Y., & Oohashi, T. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00133-7 · Cited by 114 · see citing works

Structural Characterization of Two Variants of Fibulin-1 that Differ in Nidogen Affinity

Sasaki, T., Kostka, G., Göhring, W., et al. (1995) · Journal of Molecular Biology · doi:10.1006/jmbi.1994.0020 · Cited by 109 · see citing works

Differential Regulation of Fibulin, Tenascin-C, and Nidogen Expression during Wound Healing of Normal and Glucocorticoid-Treated Mice

Fässler, R., Sasaki, T., Timpl, R., Chu, M., & Werner, S. (1996) · Experimental Cell Research · doi:10.1006/excr.1996.0014 · Cited by 106 · see citing works

The chondroitin sulphate proteoglycan brevican is upregulated by astrocytes after entorhinal cortex lesions in adult rats

Thon, N., Haas, C. A., Rauch, U., Merten, T., Fässler, R., Frotscher, M., & Deller, T. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00109.x · Cited by 104 · see citing works

The cartilage proteoglycan aggregate: assembly through combined protein—carbohydrate and protein—protein interactions

Mörgelin, M., Heinegård, D. K., Engel, J., & Paulsson, M. (1994) · Biophysical Chemistry · doi:10.1016/0301-4622(94)85024-0 · Cited by 93 · see citing works

Macaque monkey retrosplenial cortex: I. Three-dimensional and cytoarchitectonic organization

Kobayashi, Y., & Amaral, D. G. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20001023)426:3 · Cited by 83 · see citing works

Fibulin‐1 binds the amino‐terminal head of β‐amyloid precursor protein and modulates its physiological function

Ohsawa, I., Takamura, C., & Kohsaka, S. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00144.x · Cited by 73 · see citing works

Overexpression of Hyaluronan Synthase-2 Reduces the Tumorigenic Potential of Glioma Cells Lacking Hyaluronidase Activity

Enegd, B., King, J. A. J., Stylli, S. S., Paradiso, L., Kaye, A. H., & Novak, U. (2002) · Neurosurgery · doi:10.1097/00006123-200206000-00023 · Cited by 71 · see citing works

The Brain Link Protein-1 (BRAL1): cDNA Cloning, Genomic Structure, and Characterization as a Novel Link Protein Expressed in Adult Brain

Hirakawa, S., Oohashi, T., Su, W.-D., Yoshioka, H., MURAKAMI, T., Arata, J., & Ninomiya, Y. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3583 · Cited by 70 · see citing works

Modeling an extracellular environment for axonal pathfinding and fasciculation in the central nervous system

Rauch, U. (1997) · Cell and Tissue Research · doi:10.1007/s004410050940 · Cited by 69 · see citing works

Activated mouse astrocytes and T cells express similar CD44 variants. Role of CD44 in astrocyte/T cell binding

Haegel, H., Tölg, C., Hofmann‐Apitius, M., & Ceredig, R. H. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.122.5.1067 · Cited by 68 · see citing works

Reciprocal changes of CD44 and GAP-43 expression in the dentate gyrus inner molecular layer after status epilepticus in mice

Borges, K., McDermott, D. L., & Dingledine, R. J. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.03.019 · Cited by 46 · see citing works

Heparan sulphate proteoglycans interact with neurocan and promote neurite outgrowth from cerebellar granule cells

Akita, K., Toda, M., HOSOKI, Y., Inoue, M., Fushiki, S., Oohira, A., Okayama, M., Yamashina, I., & Nakada, H. (2004) · Biochemical Journal · doi:10.1042/bj20040585 · Cited by 45 · see citing works

Perturbation of CD44 function affects chiasmatic routing of retinal axons in brain slice preparations of the mouse retinofugal pathway

Lin, L., & Chan, S. O. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02686.x · Cited by 43 · see citing works

Cartilage link protein interacts with neurocan, which shows hyaluronan binding characteristics different from CD44 and TSG-6

Rauch, U., Hirakawa, S., Oohashi, T., Kappler, J., & Roos, G. (2004) · Matrix Biology · doi:10.1016/j.matbio.2003.11.007 · Cited by 42 · see citing works

Characterization of dermacan, a novel zebrafish lectican gene, expressed in dermal bones

Kang, J. S., Oohashi, T., Kawakami, Y., Bekku, Y., Belmonte, J. C. I., & Ninomiya, Y. (2004) · Mechanisms of Development · doi:10.1016/j.mod.2004.01.007 · Cited by 37 · see citing works

Neurocan–GFP Fusion Protein

Zhang, H., Baader, S. L., Sixt, M., Kappler, J., & Rauch, U. (2004) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.3a6221.2004 · Cited by 33 · see citing works

Ultrastructural localization of microfibrillar fibulin-1 and fibulin-2 during heart development indicates a switch in molecular associations

Miosge, N., Sasaki, T., Chu, M.-L., et al. (1998) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050188 · Cited by 31 · see citing works

Neurocan Is a Heparin Binding Proteoglycan

Feng, K., Arnold-Ammer, I., & Rauch, U. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.2823 · Cited by 11 · see citing works

Extracellular matrix of the central nervous system: from neglect to challenge

Zimmermann, D. R., & Dours-Zimmermann, M. T. (2008) · Histochemistry and Cell Biology · doi:10.1007/s00418-008-0485-9 · Cited by 465 · see citing works

Activity‐dependent formation and functions of chondroitin sulfate‐rich extracellular matrix of perineuronal nets

Dityatev, A., Brückner, G., Dityateva, G., Grosche, J., Kleene, R., & Schachner, M. (2007) · Developmental Neurobiology · doi:10.1002/dneu.20361 · Cited by 365 · see citing works

Perineuronal net formation and structure in aggrecan knockout mice

Giamanco, K. A., Morawski, M., & Matthews, R. T. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.08.032 · Cited by 207 · see citing works

Contributions of astrocytes to synapse formation and maturation — Potential functions of the perisynaptic extracellular matrix

Faissner, A., Pyka, M., Geissler, M., Sobik, T., Frischknecht, R., Gundelfinger, E. D., & Seidenbecher, C. (2010) · Brain Research Reviews · doi:10.1016/j.brainresrev.2010.01.001 · Cited by 207 · see citing works

Extracellular matrix abnormalities in schizophrenia

Berretta, S. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.08.010 · Cited by 179 · see citing works

Upregulation of aggrecan, link protein 1, and hyaluronan synthases during formation of perineuronal nets in the rat cerebellum

Carulli, D., Rhodes, K. E., & Fawcett, J. W. (2007) · Journal of Comparative Neurology · doi:10.1002/cne.21231 · Cited by 158 · see citing works

Primary Hippocampal Neurons, Which Lack Four Crucial Extracellular Matrix Molecules, Display Abnormalities of Synaptic Structure and Function and Severe Deficits in Perineuronal Net Formation

Geissler, M., Gottschling, C., Aguado, A., Rauch, U., Wetzel, C. H., Hatt, H., & Faissner, A. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3275-12.2013 · Cited by 140 · see citing works

Neuron-Glia Interactions in Neural Plasticity: Contributions of Neural Extracellular Matrix and Perineuronal Nets

Dzyubenko, E., Gottschling, C., & Faissner, A. (2016) · Neural Plasticity · doi:10.1155/2016/5214961 · Cited by 134 · see citing works

Brevican-containing perineuronal nets of extracellular matrix in dissociated hippocampal primary cultures

John, N., Krügel, H., Frischknecht, R., Smalla, K.-H., Schultz, C., Kreutz, M. R., Gundelfinger, E. D., & Seidenbecher, C. I. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2006.01.011 · Cited by 122 · see citing works

Elimination of the four extracellular matrix molecules tenascin-C, tenascin-R, brevican and neurocan alters the ratio of excitatory and inhibitory synapses

Gottschling, C., Wegrzyn, D., Denecke, B., & Faissner, A. (2019) · Scientific Reports · doi:10.1038/s41598-019-50404-9 · Cited by 111 · see citing works

Bral2 is indispensable for the proper localization of brevican and the structural integrity of the perineuronal net in the brainstem and cerebellum

Bekku, Y., Saito, M., Moser, M., Fuchigami, M., Maehara, A., Nakayama, M., Kusachi, S., Ninomiya, Y., & Oohashi, T. (2012) · Journal of Comparative Neurology · doi:10.1002/cne.23009 · Cited by 65 · see citing works

Chemistry and Function of Glycosaminoglycans in the Nervous System

Schwartz, N. B., & Domowicz, M. S. (2014) · Advances in Neurobiology · doi:10.1007/978-1-4939-1154-7_5 · Cited by 25 · see citing works

Intrinsic cellular and molecular properties of in vivo hippocampal synaptic plasticity are altered in the absence of key synaptic matrix molecules

Jansen, S., Gottschling, C., Faissner, A., & Manahan‐Vaughan, D. (2017) · Hippocampus · doi:10.1002/hipo.22742 · Cited by 26 · see citing works

Tenascin-C induces expression of the Notch ligand Jagged1 to promote glioma growth

Parmigiani, E., Taylor, V., & Giachino, C. (2017) · Translational Cancer Research · doi:10.21037/14965

Tenascin-C protein is induced by Transforming Growth Factor-ß1 but does not correlate with time to tumor progression in high-grade gliomas

Hau, P., Kunz‐Schughart, L. A., Rümmele, P., Arslan, F., Doerfelt, A., Koch, H. J., Lohmeier, A., Hirschmann, B., Müller, A., Bogdahn, U., et al. (2005) · Journal of Neuro-Oncology · doi:10.1007/s11060-005-9000-5 · Cited by 23 · see citing works

Clinical impact and functional aspects of tenascin‐C expression during glioma progression

Herold‐Mende, C. C., Mueller, M. M., Bonsanto, M. M., Schmitt, H. P., Kunze, S., & Steiner, H. H. (2002) · International Journal of Cancer · doi:10.1002/ijc.10233 · Cited by 169 · see citing works

Tenascins

Chiquet‐Ehrismann, R. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2003.12.002 · Cited by 122 · see citing works

Structural Motifs of the Extracellular Matrix Proteins Laminin and Tenascin

Beck, K., Spring, J., Chiquet‐Ehrismann, R., Engel, J., & Chiquet, M. (1992) · Springer series in biophysics · doi:10.1007/978-3-642-76637-4_21 · Cited by 12 · see citing works