Contributions of astrocytes to synapse formation and maturation — Potential functions of the perisynaptic extracellular matrix

The Classical Complement Cascade Mediates CNS Synapse Elimination

Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.036 · Cited by 3,313 · see citing works

The Molecular Biology of Axon Guidance

Tessier‐Lavigne, M., & Goodman, C. S. (1996) · Science · doi:10.1126/science.274.5290.1123 · Cited by 3,295 · see citing works

Tripartite synapses: glia, the unacknowledged partner

Araque, A., Parpura, V., Sanzgiri, R. P., & Haydon, P. G. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01349-6 · Cited by 2,529 · see citing works

CNS synaptogenesis promoted by glia-derived cholesterol

Mauch, D. H., Nägler, K., Schumacher, S., Göritz, C., Müller, E.-C., Otto, A., & Pfrieger, F. W. (2001) · Science · doi:10.1126/science.294.5545.1354 · Cited by 1,711 · see citing works

Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis

Christopherson, K. S., Ullian, E. M., Stokes, C. C. A., Mullowney, C. E., Hell, J. W., Agah, A., Lawler, J., Mosher, D. F., Bornstein, P., & Barres, B. A. (2005) · Cell · doi:10.1016/j.cell.2004.12.020 · Cited by 1,688 · see citing works

Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex

Pizzorusso, T., Medini, P., Berardi, N., Chierzi, S., Fawcett, J. W., & Maffei, L. (2002) · Science · doi:10.1126/science.1072699 · Cited by 1,679 · see citing works

DEVELOPMENT OF THE VERTEBRATE NEUROMUSCULAR JUNCTION

Sanes, J. R., & Lichtman, J. W. (1999) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.22.1.389 · Cited by 1,532 · see citing works

Astroglia induce neurogenesis from adult neural stem cells

Song, H., Stevens, C. F., & Gage, F. H. (2002) · Nature · doi:10.1038/417039a · Cited by 1,452 · see citing works

Molecular Mechanisms of Axon Guidance

Dickson, B. J. (2002) · Science · doi:10.1126/science.1072165 · Cited by 1,431 · see citing works

Glia: listening and talking to the synapse

Haydon, P. G. (2001) · Nature reviews. Neuroscience · doi:10.1038/35058528 · Cited by 1,410 · see citing works

Control of Synapse Number by Glia

Ullian, E. M., Sapperstein, S. K., Christopherson, K. S., & Barres, B. A. (2001) · Science · doi:10.1126/science.291.5504.657 · Cited by 1,380 · see citing works

Control of Synaptic Strength by Glial TNFα

Beattie, E. C., Stellwagen, D., Morishita, W., Bresnahan, J. C., Ha, B. K., Von Zastrow, M., Beattie, M. S., & Malenka, R. C. (2002) · Science · doi:10.1126/science.1067859 · Cited by 1,344 · see citing works

PSD-95 Involvement in Maturation of Excitatory Synapses

El-Husseini, A. E.-D., Schnell, E., Chetkovich, D. M., Nicoll, R. A., & Bredt, D. S. (2000) · Science · doi:10.1126/science.290.5495.1364 · Cited by 1,303 · see citing works

Purification and Properties of Bacterial Chondroitinases and Chondrosulfatases

Yamagata, T., Saito, H., Habuchi, O., & Suzuki, S. (1968) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)93574-x · Cited by 1,238 · see citing works

Functional atlas of the integrin adhesome

Zaidel‐Bar, R., Itzkovitz, S., Ma’ayan, A., Iyengar, R., & Geiger, B. (2007) · Nature Cell Biology · doi:10.1038/ncb0807-858 · Cited by 1,182 · see citing works

Induction, assembly, maturation and maintenance of a postsynaptic apparatus

Sanes, J. R., & Lichtman, J. W. (2001) · Nature reviews. Neuroscience · doi:10.1038/35097557 · Cited by 1,025 · see citing works

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

Eroglu, Ç., Allen, N. J., Susman, M. W., O'Rourke, N. A., Park, C. Y., Özkan, E., Chakraborty, C., Mulinyawe, S. B., Annis, D. S., Huberman, A. D., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.025 · Cited by 893 · see citing works

Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS

Filbin, M. T. (2003) · Nature reviews. Neuroscience · doi:10.1038/nrn1195 · Cited by 873 · see citing works

Synaptic Efficacy Enhanced by Glial Cells in Vitro

Pfrieger, F. W., & Barres, B. A. (1997) · Science · doi:10.1126/science.277.5332.1684 · Cited by 793 · see citing works

Perineuronal Nets Protect Fear Memories from Erasure

Gogolla, N., Caroni, P., Lüthi, A., & Herry, C. (2009) · Science · doi:10.1126/science.1174146 · Cited by 760 · see citing works

An adaptive coding model of neural function in prefrontal cortex

Duncan, J. (2001) · UCL Discovery (University College London) · Cited by 738 · see citing works

A Striking Organization of a Large Family of Human Neural Cadherin-like Cell Adhesion Genes

Wu, Q., & Maniatis, T. (1999) · Cell · doi:10.1016/s0092-8674(00)80789-8 · Cited by 714 · see citing works

Lecticans: organizers of the brain extracellular matrix

Yamaguchi, Y. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000690 · Cited by 642 · see citing works

Proteoglycans in the Developing Brain: New Conceptual Insights for Old Proteins

Bandtlow, C. E., & Zimmermann, D. R. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.4.1267 · Cited by 632 · see citing works

Cell adhesion molecules: signalling functions at the synapse

Dalva, M. B., McClelland, A. C., & Kayser, M. S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2075 · Cited by 620 · see citing works

Dynamic Signaling Between Astrocytes and Neurons

Araque, A., Carmignoto, G., & Haydon, P. G. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.795 · Cited by 611 · see citing works

Extracellular matrix molecules and synaptic plasticity

Dityatev, A., & Schachner, M. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1115 · Cited by 564 · see citing works

Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity

Frischknecht, R., Heine, M., Perrais, D., Seidenbecher, C. I., Choquet, D., & Gundelfinger, E. D. (2009) · Nature Neuroscience · doi:10.1038/nn.2338 · Cited by 554 · see citing works

Activity-dependent structural and functional plasticity of astrocyte-neuron interactions

Theodosis, D. T., Poulain, D. A., & Oliet, S. H. R. (2008) · Physiological Reviews · doi:10.1152/physrev.00036.2007 · Cited by 531 · see citing works

Surface Mobility of Postsynaptic AMPARs Tunes Synaptic Transmission

Heine, M., Groc, L., Frischknecht, R., Béïque, J.-C., Lounis, B., Rumbaugh, G., Huganir, R. L., Cognet, L., & Choquet, D. (2008) · Science · doi:10.1126/science.1152089 · Cited by 518 · see citing works

Perineuronal nets: past and present

Celio, M. R., Spreafico, R., De Biasi, S., & Vitellaro-Zuccarello, L. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01298-3 · Cited by 497 · see citing works

Breaking the neuronal sphere: regulation of the actin cytoskeleton in neuritogenesis

Silva, J. S. D., & Dotti, C. G. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn918 · Cited by 474 · see citing works

The cadherin superfamily in neuronal connections and interactions

Takeichi, M. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn2043 · Cited by 433 · see citing works

Bidirectional modulation of synaptic functions by Eph/ephrin signaling

Klein, R. (2008) · Nature Neuroscience · doi:10.1038/nn.2231 · Cited by 419 · see citing works

The role of receptor diffusion in the organization of the postsynaptic membrane

Choquet, D., & Triller, A. (2003) · Nature reviews. Neuroscience · doi:10.1038/nrn1077 · Cited by 410 · see citing works

Perineuronal nets — a specialized form of extracellular matrix in the adult nervous system

Celio, M. R., & Blümcke, I. (1994) · Brain Research Reviews · doi:10.1016/0165-0173(94)90006-x · Cited by 386 · see citing works

Role for glia in synaptogenesis

Ullian, E. M., Christopherson, K. S., & Barres, B. A. (2004) · Glia · doi:10.1002/glia.20082 · Cited by 370 · see citing works

Fine structural and cytochemical analysis of the staining of synaptic junctions with phosphotungstic acid

Bloom, F. E., & Aghajanian, G. K. (1968) · Journal of Ultrastructure Research · doi:10.1016/s0022-5320(68)90027-0 · Cited by 367 · see citing works

Structural and functional recovery from early monocular deprivation in adult rats

Pizzorusso, T., Medini, P., Landi, S., Baldini, S., Berardi, N., & Maffei, L. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602657103 · Cited by 367 · see citing works

Activity‐dependent formation and functions of chondroitin sulfate‐rich extracellular matrix of perineuronal nets

Dityatev, A., Brückner, G., Dityateva, G., Grosche, J., Kleene, R., & Schachner, M. (2007) · Developmental Neurobiology · doi:10.1002/dneu.20361 · Cited by 365 · see citing works

Perineuronal nets provide a polyanionic, glia‐associated form of microenvironment around certain neurons in many parts of the rat brain

Brückner, G., Brauer, K., Härtig, W., Wolff, J. R., Rickmann, M. J., Derouiche, A., Delpech, B., Girard, N., Oertel, W. H., & Reichenbach, A. (1993) · Glia · doi:10.1002/glia.440080306 · Cited by 358 · see citing works

Isolation of a neural chondroitin sulfate proteoglycan with neurite outgrowth promoting properties.

Faissner, A., Clement, A. M., Lochter, A., Streit, A., Mandl, C., & Schachner, M. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.126.3.783 · Cited by 354 · see citing works

Aggrecan Glycoforms Contribute to the Molecular Heterogeneity of Perineuronal Nets

Matthews, R. T., Kelly, G. M., Zerillo, C. A., Gray, G., Tiemeyer, M., & Hockfield, S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-17-07536.2002 · Cited by 341 · see citing works

Composition of perineuronal nets in the adult rat cerebellum and the cellular origin of their components

Carulli, D., Rhodes, K. E., Brown, D. J., Bonnert, T. P., Pollack, S. J., Oliver, K., Strata, P., & Fawcett, J. W. (2006) · Journal of Comparative Neurology · doi:10.1002/cne.20822 · Cited by 341 · see citing works

Cortical neurons immunoreactive for the potassium channel Kv3.1b subunit are predominantly surrounded by perineuronal nets presumed as a buffering system for cations

Härtig, W., Derouiche, A., Welt, K., Brauer, K., Grosche, J., Mäder, M., Reichenbach, A., & Brückner, G. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01784-9 · Cited by 339 · see citing works

Integrins mediate functional pre- and postsynaptic maturation at a hippocampal synapse

Chavis, P., & Westbrook, G. L. (2001) · Nature · doi:10.1038/35077101 · Cited by 332 · see citing works

Topographic organization of medial pulvinar connections with the prefrontal cortex in the rhesus monkey

Romanski, L. M., Giguere, M., Bates, J. F., & Goldman-Rakic, P. S. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19970317)379:3 · Cited by 325 · see citing works

C ELL -C ELL S IGNALING D URING S YNAPSE F ORMATION IN THE CNS

Scheiffele, P. (2003) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.043002.094940 · Cited by 316 · see citing works

Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C

Garcion, E., Halilagic, A., Faissner, A., & ffrench‐Constant, C. (2004) · Development · doi:10.1242/dev.01202 · Cited by 309 · see citing works

Molecular Modification of N-Cadherin in Response to Synaptic Activity

Tanaka, H., Shan, W., Phillips, G. R., Arndt, K., Bozdagi, O., Shapiro, L. S., Huntley, G. W., Benson, D. L., & Colman, D. (2000) · Neuron · doi:10.1016/s0896-6273(00)80874-0 · Cited by 305 · see citing works

PKC signaling mediates global enhancement of excitatory synaptogenesis in neurons triggered by local contact with astrocytes.

Hama, H., Hara, C., Yamaguchi, K., & Miyawaki, A. (2004) · Neuron · doi:10.1016/s0896-6273(04)00007-8 · Cited by 290 · see citing works

Surface trafficking of receptors between synaptic and extrasynaptic membranes: and yet they do move!

Triller, A., & Choquet, D. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.01.001 · Cited by 285 · see citing works

Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport

Filosa, A., Paixão, S., Honsek, S. D., Carmona, M. A., Becker, L., Feddersen, B., Gaitanos, L., Rudhard, Y., Schoepfer, R., Klopstock, T., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2394 · Cited by 283 · see citing works

The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein– protein interactions independent of carbohydrate moiety

Aspberg, A., Miura, R., Bourdoulous, S., Shimonaka, M., Heinegård, D., Schachner, M., Ruoslahti, E., & Yamaguchi, Y. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.19.10116 · Cited by 275 · see citing works

Brevican-Deficient Mice Display Impaired Hippocampal CA1 Long-Term Potentiation but Show No Obvious Deficits in Learning and Memory

Brakebusch, C., Seidenbecher, C. I., Asztely, F., Rauch, U., Matthies, H., Meyer, H., Krug, M., Böckers, T. M., Zhou, X., Kreutz, M. R., et al. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.21.7417-7427.2002 · Cited by 264 · see citing works

The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes

Zuber, B., Nikonenko, I., Klauser, P., Müller, D., & Dubochet, J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509527102 · Cited by 263 · see citing works

Trans-Synaptic Eph Receptor-Ephrin Signaling in Hippocampal Mossy Fiber LTP

Contractor, A., Rogers, C., Maron, C., Henkemeyer, M. J., Swanson, G. T., & Heinemann, S. F. (2002) · Science · doi:10.1126/science.1069081 · Cited by 262 · see citing works

Interactions with tenascin and differential effects on cell adhesion of neurocan and phosphacan, two major chondroitin sulfate proteoglycans of nervous tissue.

Grumet, M., Milev, P., Sakurai, T., Karthikeyan, L., Bourdon, M. A., Margolis, R. K., & Margolis, R. U. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32692-3 · Cited by 255 · see citing works

[Chondroitin sulfate proteoglycans in neural development and regeneration].

Gu, W.-L., & Lu, P. (2007) · PubMed · Cited by 255 · see citing works

Glycosaminoglycans of brain during development

Margolis, R. U., Margolis, R. K., Chang, L. B., & Preti, C. (1975) · Biochemistry · doi:10.1021/bi00672a014 · Cited by 250 · see citing works

Perineuronal nets potentially protect against oxidative stress

Morawski, M., Brückner, M. K., Riederer, P., Brückner, G., & Arendt, T. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.04.017 · Cited by 246 · see citing works

Proteomics Analysis of Rat Brain Postsynaptic Density

Li, K. W., Hornshaw, M. P., van der Schors, R. C., Watson, R. B., Tate, S. A., Casetta, B., Jiménez, C. R., Gouwenberg, Y., Gundelfinger, E. D., Smalla, K., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m303116200 · Cited by 246 · see citing works

Vav family GEFs link activated ephs to endocytosis and axon guidance

Cowan, C. W., Shao, Y. R., Sahin, M., Shamah, S. M., Lin, M. Z., Greer, P. L., Gao, S., Griffith, E. C., Brugge, J. S., & Greenberg, M. E. (2005) · Neuron · doi:10.1016/j.neuron.2005.03.019 · Cited by 246 · see citing works

Molecular cloning of brevican, a novel brain proteoglycan of the aggrecan/versican family

Yamada, H., Watanabe, K., Shimonaka, M., & Yamaguchi, Y. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36998-3 · Cited by 243 · see citing works

Modification of extracellular matrix by enzymatic removal of chondroitin sulfate and by lack of tenascin-R differentially affects several forms of synaptic plasticity in the hippocampus

Bukalo, O., Schachner, M., & Dityatev, A. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00082-3 · Cited by 236 · see citing works

Knockout mice reveal a contribution of the extracellular matrix molecule tenascin-C to neural precursor proliferation and migration

Garcion, E., Faissner, A., & ffrench‐Constant, C. (2001) · Development · doi:10.1242/dev.128.13.2485 · Cited by 235 · see citing works

Tenascin-R mediates activity-dependent recruitment of neuroblasts in the adult mouse forebrain

Saghatelyan, A., de Chevigny, A., Schachner, M., & Lledo, P. (2004) · Nature Neuroscience · doi:10.1038/nn1211 · Cited by 229 · see citing works

New roles for astrocytes: Regulation of CNS synaptogenesis

Ślęzak, M., & Pfrieger, F. W. (2003) · Trends in Neurosciences · doi:10.1016/j.tins.2003.08.005 · Cited by 224 · see citing works

Hyaluronic acid and hyaluronic acid-binding proteins in brain extracellular matrix

Bignami, A., Hosley, M., & Dahl, D. R. (1993) · Anatomy and Embryology · doi:10.1007/bf00190136 · Cited by 224 · see citing works

Differential regulation of expression of hyaluronan-binding proteoglycans in developing brain: aggrecan, versican, neurocan, and brevican.

Milev, P., Maurel, P., Chiba, A., Mevissen, M., Popp, S., Yamaguchi, Y., Margolis, R. K., & Margolis, R. U. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.8759 · Cited by 219 · see citing works

Tenascin-R Is a Functional Modulator of Sodium Channel β Subunits

Xiao, Z., Ragsdale, D. S., Malhotra, J. D., Mattei, L. N., Braun, P. E., Schachner, M., & Isom, L. L. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.37.26511 · Cited by 211 · see citing works

Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport

Carmona, M. A., Murai, K. K., Wang, L., Roberts, A. J., & Pasquale, E. B. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903328106 · Cited by 208 · see citing works

Reduced Perisomatic Inhibition, Increased Excitatory Transmission, and Impaired Long-Term Potentiation in Mice Deficient for the Extracellular Matrix Glycoprotein Tenascin-R

Saghatelyan, A. K., Dityatev, A., Schmidt, S., Schuster, T., Bartsch, U., & Schachner, M. (2001) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2000.0922 · Cited by 207 · see citing works

Molecular mechanisms of CNS synaptogenesis

Garner, C. C., Zhai, R. G., Gundelfinger, E. D., & Ziv, N. E. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02152-5 · Cited by 206 · see citing works

Neurocan Is Dispensable for Brain Development

Zhou, X.-H., Brakebusch, C., Matthies, H., Oohashi, T., Hirsch, E., Moser, M., Krug, M., Seidenbecher, C. I., Boeckers, T. M., Rauch, U., et al. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.17.5970-5978.2001 · Cited by 206 · see citing works

Extracellular matrix components associated with remodeling processes in brain

Rauch, U. (2004) · Cellular and Molecular Life Sciences (CMLS) · doi:10.1007/s00018-004-4043-x · Cited by 205 · see citing works

Glia‐derived signals induce synapse formation in neurones of the rat central nervous system

Nägler, K., Mauch, D. H., & Pfrieger, F. W. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.00665.x · Cited by 203 · see citing works

Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin‐R in the rat spinal cord

Galtrey, C. M., Kwok, J. C. F., Carulli, D., Rhodes, K. E., & Fawcett, J. W. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06108.x · Cited by 203 · see citing works

Astrocyte-induced modulation of synaptic transmission

Araque, A., Sanzgiri, R. P., Parpura, V., & Haydon, P. G. (1999) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y99-076 · Cited by 201 · see citing works

The formation of neuromuscular synapsesPreprint

Burden, S. J. (1998) · Genes & Development · doi:10.1101/gad.12.2.133 · Cited by 188 · see citing works

Properly formed but improperly localized synaptic specializations in the absence of laminin α4

Patton, B. L., Cunningham, J. M., Thyboll, J., Kortesmaa, J., Westerblad, H., Edström, L., Tryggvason, K., & Sanes, J. R. (2001) · Nature Neuroscience · doi:10.1038/88414 · Cited by 187 · see citing works

The DSD-1 Carbohydrate Epitope Depends on Sulfation, Correlates with Chondroitin Sulfate D Motifs, and Is Sufficient to Promote Neurite Outgrowth

Clement, A. M., Nadanaka, S., Masayama, K., Mandl, C., Sugahara, K., & Faissner, A. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.43.28444 · Cited by 175 · see citing works

Impairment of L-type Ca²⁺Channel-Dependent Forms of Hippocampal Synaptic Plasticity in Mice Deficient in the Extracellular Matrix Glycoprotein Tenascin-C

Evers, M. R., Salmen, B., Bukalo, O., Rollenhagen, A., Bösl, M. R., Morellini, F., Bartsch, U., Dityatev, A., & Schachner, M. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-16-07177.2002 · Cited by 172 · see citing works

DSD-1-Proteoglycan Is the Mouse Homolog of Phosphacan and Displays Opposing Effects on Neurite Outgrowth Dependent on Neuronal Lineage

Garwood, J., Schnädelbach, O., Clement, A. M., Schütte, K., Bach, A., & Faissner, A. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-10-03888.1999 · Cited by 168 · see citing works

Schwann cells and astrocytes induce synapse formation by spinal motor neurons in culture

Ullian, E. M., Harris, B. T., Wu, A. W., Chan, J. R., & Barres, B. A. (2004) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2003.10.011 · Cited by 158 · see citing works

Schwann Cells Promote Synaptogenesis at the Neuromuscular Junction via Transforming Growth Factor-β1

Feng, Z., & Ko, C.-P. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2589-08.2008 · Cited by 157 · see citing works

Chondroitin sulfate proteoglycans in neural development and regeneration

Carulli, D., Laabs, T. L., Geller, H. M., & Fawcett, J. W. (2005) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.03.018 · Cited by 154 · see citing works

Characteristic Hexasaccharide Sequences in Octasaccharides Derived from Shark Cartilage Chondroitin Sulfate D with a Neurite Outgrowth Promoting Activity

Nadanaka, S., Clement, A. M., Masayama, K., Faissner, A., & Sugahara, K. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.6.3296 · Cited by 150 · see citing works

Brevican, a Chondroitin Sulfate Proteoglycan of Rat Brain, Occurs as Secreted and Cell Surface Glycosylphosphatidylinositol-anchored Isoforms

Seidenbecher, C. I., Richter, K., Rauch, U., Fässler, R., Garner, C. C., & Gundelfinger, E. D. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.45.27206 · Cited by 149 · see citing works

Immunocytochemical localization of a chondroitin sulfate proteoglycan in nervous tissue. I. Adult brain, retina, and peripheral nerve.

Aquino, D. A., Margolis, R. U., & Margolis, R. K. (1984) · The Journal of Cell Biology · doi:10.1083/jcb.99.3.1117 · Cited by 148 · see citing works

Synaptic laminin prevents glial entry into the synaptic cleft

Patton, B. L., Chiu, A. Y., & Sanes, J. R. (1998) · Nature · doi:10.1038/31502 · Cited by 143 · see citing works

A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions

Harroch, S., Furtado, G. C., Brück, W., D, J. R. M., Lafaille, J. J., Chao, M. V., Buxbaum, J. D., & Schlessinger, J. (2002) · Nature Genetics · doi:10.1038/ng1004 · Cited by 140 · see citing works

Structural and Functional Aberrations in the Cerebral Cortex of Tenascin-C Deficient Mice

Irintchev, A., Rollenhagen, A., Troncoso, E., Kiss, J. Z., & Schachner, M. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhh195 · Cited by 137 · see citing works

The extracellular matrix and synapses

Dityatev, A., & Schachner, M. (2006) · Cell and Tissue Research · doi:10.1007/s00441-006-0217-1 · Cited by 128 · see citing works

Immunocytochemical localization of a chondroitin sulfate proteoglycan in nervous tissue. II. Studies in developing brain.

Aquino, D. A., Margolis, R. U., & Margolis, R. K. (1984) · The Journal of Cell Biology · doi:10.1083/jcb.99.3.1130 · Cited by 126 · see citing works

Glial diffusion barriers during aging and pathological states

Syková, E. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)32087-3 · Cited by 124 · see citing works

Brevican-containing perineuronal nets of extracellular matrix in dissociated hippocampal primary cultures

John, N., Krügel, H., Frischknecht, R., Smalla, K.-H., Schultz, C., Kreutz, M. R., Gundelfinger, E. D., & Seidenbecher, C. I. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2006.01.011 · Cited by 122 · see citing works

The extracellular matrix molecule tenascin‐R and its HNK‐1 carbohydrate modulate perisomatic inhibition and long‐term potentiation in the CA1 region of the hippocampus

Saghatelyan, A., Gorissen, S., Albert, M., Hertlein, B., Schachner, M., & Dityatev, A. E. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00216.x · Cited by 117 · see citing works

Extracellular matrix in plasticity and epileptogenesis

Dityatev, A. E., & Fellin, T. (2008) · Neuron Glia Biology · doi:10.1017/s1740925x09000118 · Cited by 116 · see citing works

Structural characterization of the epitopes of the monoclonal antibodies 473HD, CS-56, and MO-225 specific for chondroitin sulfate D-type using the oligosaccharide library

Ito, Y., Hikino, M., Yajima, Y., Mikami, T., Sirko, S., von Holst, A., Faissner, A., Fukui, S., & Sugahara, K. (2004) · Glycobiology · doi:10.1093/glycob/cwi036 · Cited by 114 · see citing works

RhoA Regulates Dendrite Branching in Hippocampal Neurons by Decreasing Cypin Protein Levels

Chen, H., & Firestein, B. L. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0872-07.2007 · Cited by 107 · see citing works

Diffuse perineuronal nets and modified pyramidal cells immunoreactive for glutamate and the GABAA receptor α1 subunit form a unique entity in rat cerebral cortex

Wegner, F., Härtig, W., Bringmann, A., Grosche, J., Wohlfarth, K., Zuschratter, W., & Brückner, G. (2003) · Experimental Neurology · doi:10.1016/s0014-4886(03)00313-3 · Cited by 107 · see citing works

Coincident Pre- and Postsynaptic Activation Induces Dendritic Filopodia via Neurotrypsin-Dependent Agrin Cleavage

Matsumoto, K., Sokolowska, E., Zurlinden, A., Gee, C. E., Lüscher, D., Hettwer, S., Wölfel, J., Ladner, A. P., Ster, J., Gerber, U. R., et al. (2009) · Cell · doi:10.1016/j.cell.2009.02.034 · Cited by 105 · see citing works

The extracellular matrix glycoprotein Tenascin‐C is expressed by oligodendrocyte precursor cells and required for the regulation of maturation rate, survival and responsiveness to platelet‐derived growth factor

Garwood, J., Garcion, E., Dobbertin, A., Heck, N., Calco, V., ffrench‐Constant, C., & Faissner, A. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03727.x · Cited by 104 · see citing works

Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS

Bekku, Y., Rauch, U., Ninomiya, Y., & Oohashi, T. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.05873.x · Cited by 104 · see citing works

Decomposition and long-lasting downregulation of extracellular matrix in perineuronal nets induced by focal cerebral ischemia in rats.

Hobohm, C., Günther, A., Grosche, J., Roßner, S., Schneider, D., & Brückner, G. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20459 · Cited by 103 · see citing works

Distribution of pyramidal cells associated with perineuronal nets in the neocortex of rat

Alpár, A., Gärtner, U., Härtig, W., & Brückner, G. (2006) · Brain Research · doi:10.1016/j.brainres.2006.08.069 · Cited by 93 · see citing works

Postsynaptic EphrinB3 Promotes Shaft Glutamatergic Synapse Formation

Aoto, J. N., Ting, P. Y., Maghsoodi, B., Xu, N., Henkemeyer, M. J., & Chen, L. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0705-07.2007 · Cited by 93 · see citing works

Somatic mosaicism for an HRAS mutation causes Costello syndrome

Gripp, K. W., Stabley, D. L., Nicholson, L., Hoffman, J. D., & Sol‐Church, K. (2006) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.31456 · Cited by 92 · see citing works

Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA‐dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway

Czopka, T., von Holst, A., Schmidt, G., ffrench-Constant, C., & Faissner, A. (2009) · Glia · doi:10.1002/glia.20891 · Cited by 90 · see citing works

Extracellular matrix alterations in brains lacking four of its components

Rauch, U., Zhou, X.-H., & Roos, G. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.01.026 · Cited by 88 · see citing works

The crosstalk of hyaluronan-based extracellular matrix and synapses

Frischknecht, R., & Seidenbecher, C. I. (2008) · Neuron Glia Biology · doi:10.1017/s1740925x09990226 · Cited by 84 · see citing works

Regulation of RPTPβ/phosphacan expression and glycosaminoglycan epitopes in injured brain and cytokine-treated glia

Dobbertin, A., Rhodes, K. E., Garwood, J., Properzi, G., Heck, N., ROGERS, J. H., Fawcett, J. W., & Faissner, A. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00257-4 · Cited by 82 · see citing works

Hippocampal Metaplasticity Induced by Deficiency in the Extracellular Matrix Glycoprotein Tenascin-R

Bukalo, O., Schachner, M., & Dityatev, A. E. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1022-07.2007 · Cited by 80 · see citing works

Severe cognitive and motor coordination deficits in Tenascin‐R‐deficient mice

Sallaz, M., & Montag, D. (2003) · Genes Brain & Behavior · doi:10.1034/j.1601-183x.2003.00003.x · Cited by 80 · see citing works

Schwann Cells Express Active Agrin and Enhance Aggregation of Acetylcholine Receptors on Muscle Fibers

Yang, J., Cao, G., Koirala, S., Reddy, L. V., & Ko, C. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-24-09572.2001 · Cited by 80 · see citing works

The Role of Glial Cells in the Formation and Maintenance of the Neuromuscular Junction

Feng, Z., & Ko, C. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1405.016 · Cited by 74 · see citing works

Tenascin‐R–deficient mice show structural alterations of symmetric perisomatic synapses in the CA1 region of the hippocampus

Nikonenko, A., Schmidt, S., Skibo, G., Brückner, G., & Schachner, M. (2003) · Journal of Comparative Neurology · doi:10.1002/cne.10537 · Cited by 69 · see citing works

Bidirectional ephrin/Eph signaling in synaptic functions

Aoto, J. N., & Chen, L. (2006) · Brain Research · doi:10.1016/j.brainres.2006.11.033 · Cited by 67 · see citing works

The Adult Mouse Subependymal Zone Regenerates Efficiently in the Absence of Tenascin-C

Kazanis, I., Belhadi, A., Faissner, A., & ffrench‐Constant, C. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3279-07.2007 · Cited by 63 · see citing works

Discrete reduction patterns of parvalbumin and calbindin D-28k immunoreactivity in the dorsal lateral geniculate nucleus and the striate cortex of adult macaque monkeys after monocular enucleation

Blümcke, I., Weruaga, E., Kasas, S., Hendrickson, A. E., & Celio, M. R. (1994) · Visual Neuroscience · doi:10.1017/s0952523800011056 · Cited by 62 · see citing works

Morphology of perineuronal nets in tenascin-R and parvalbumin single and double knockout mice

Haunsø, A., Ibrahim, M., Bartsch, U., Letiembre, M., Celio, M. R., & Menoud, P.-A. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02173-9 · Cited by 61 · see citing works

Opposite impacts of tenascin‐C and tenascin‐R deficiency in mice on the functional outcome of facial nerve repair

Guntinas‐Lichius, O., Angelov, D. N., Morellini, F., Lenzen, M., Skouras, E., Schachner, M., & Irintchev, A. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04424.x · Cited by 55 · see citing works

Protein tyrosine phosphatase ζ/RPTPβ interacts with PSD-95/SAP90 family

Kawachi, H., Tamura, H., Watakabe, I., Shintani, T., Maeda, N., & Noda, M. (1999) · Molecular Brain Research · doi:10.1016/s0169-328x(99)00204-1 · Cited by 50 · see citing works

Differential expression of tenascin after denervation, damage or paralysis of mouse soleus muscle

Irintchev, A., Salvini, T. F., Faissner, A., & Wernig, A. (1993) · Journal of Neurocytology · doi:10.1007/bf01218353 · Cited by 47 · see citing works

Neuronal–glial remodeling: a structural basis for neuronal–glial interactions in the adult hypothalamus

Langle, S. L., Poulain, D. A., & Theodosis, D. T. (2002) · Journal of Physiology-Paris · doi:10.1016/s0928-4257(02)00003-7 · Cited by 45 · see citing works

Cytochemistry of synaptosomes

Bondareff, W., & Sjöstrand, J. (1969) · Experimental Neurology · doi:10.1016/0014-4886(69)90148-4 · Cited by 43 · see citing works

The peripheral nerve and the neuromuscular junction are affected in the tenascin-C-deficient mouse.

Cifuentes-Díaz, C., Velasco, E., Meunier, F. A., Goudou, D., Belkadi, L., Faille, L., Murawsky, M., Angaut‐Petit, D., Molgó, J., Schachner, M., et al. (1998) · PubMed · Cited by 41 · see citing works

Delayed onset of odor detection in neonatal mice lacking tenascin-C

de Chevigny, A., Lemasson, M., Saghatelyan, A., Sibbe, M., Schachner, M., & Lledo, P. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2006.04.002 · Cited by 40 · see citing works

Genetic ablation of tenascin‐C expression leads to abnormal hippocampal CA1 structure and electrical activity in vivo

Gurevicius, K., Kuang, F., Stoenica, L., Irintchev, A., Gureviciene, I., Dityatev, A. E., Schachner, M., & Tanila, H. (2009) · Hippocampus · doi:10.1002/hipo.20585 · Cited by 40 · see citing works

Tenascin-R Promotes Neuronal Differentiation of Embryonic Stem Cells and Recruitment of Host-Derived Neural Precursor Cells After Excitotoxic Lesion of the Mouse Striatum

Hargus, G., Cui, Y., Schmid, J. S., Xu, J., Glatzel, M., Schachner, M., & Bernreuther, C. (2008) · Stem Cells · doi:10.1634/stemcells.2007-0929 · Cited by 40 · see citing works

Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity

Reimers, S., Hartlage‐Rübsamen, M., Brückner, G., & Roßner, S. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05514.x · Cited by 38 · see citing works

The Ras-GRF1 Exchange Factor Coordinates Activation of H-Ras and Rac1 to Control Neuronal Morphology

Yang, H., & Mattingly, R. R. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-10-0913 · Cited by 34 · see citing works

Perineuronal Nets Characterized by Vital Labelling, Confocal and Electron Microscopy in Organotypic Slice Cultures of Rat Parietal Cortex and Hippocampus

Brückner, G., Kacza, J., & Grosche, J. (2004) · Journal of Molecular Histology · doi:10.1023/b:hijo.0000023374.22298.50 · Cited by 33 · see citing works

Abnormal reinnervation of skeletal muscle in a tenascin‐C‐deficient mouse

Cifuentes-Díaz, C., Faille, L., Goudou, D., Schachner, M., Rieger, F., & Angaut‐Petit, D. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.10109 · Cited by 31 · see citing works

Tenascin-C stimulates contactin-dependent neurite outgrowth via activation of phospholipase C

Michele, M., & Faissner, A. (2009) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2009.04.004 · Cited by 28 · see citing works

Comparative screening of glial cell types reveals extracellular matrix that inhibits retinal axon growth in a chondroitinase ABC‐resistant fashion

Siddiqui, S., Horvat‐Broecker, A., & Faissner, A. (2009) · Glia · doi:10.1002/glia.20860 · Cited by 26 · see citing works

Reduced plasticity of cortical whisker representation in adult tenascin‐C‐deficient mice after vibrissectomy

Cybulska-Kłosowicz, A., Zakrzewska, R., Pyza, E., Kossut, M. M., & Schachner, M. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03605.x · Cited by 21 · see citing works

Preprotachykinin A and cholecystokinin mRNAs in tenascin-gene knockout mouse brain

Fukamauchi, F., & Kusakabe, M. (1997) · Neuropeptides · doi:10.1016/s0143-4179(97)90090-1 · Cited by 14 · see citing works

Novel conserved oligodendrocyte surface epitope identified by monoclonal antibody 4860

Czopka, T., Hennen, E., von Holst, A., & Faissner, A. (2009) · Cell and Tissue Research · doi:10.1007/s00441-009-0868-9 · Cited by 11 · see citing works

The effects of central administration of neuropeptide Y on behavior of tenascin-gene knockout mice

Fukamauchi, F., Aihara, O., & Kusakabe, M. (1998) · Neuropeptides · doi:10.1016/s0143-4179(98)90072-5 · Cited by 10 · see citing works

Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R

Br�ckner, G., Grosche, J., Schmidt, S., H�rtig, W., Margolis, R. U., Delpech, B., Seidenbecher, C. I., Czaniera, R., & Schachner, M. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20001225)428:4

Untitled work

Hagihara (1999) · doi:10.1002/(sici)1096-9861(19990726)410:2

Physiology of Astroglia

Verkhratsky, A., & Nedergaard, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00042.2016 · Cited by 1,678 · see citing works

Neuroinflammation: The role and consequences

Lyman, M., Lloyd, D. G., Ji, X., Vizcaychipi, M. P., & Ma, D. (2013) · Neuroscience Research · doi:10.1016/j.neures.2013.10.004 · Cited by 740 · see citing works

Toll‐like receptor 4 is required for α‐synuclein dependent activation of microglia and astroglia

Fellner, L., Irschick, R., Schanda, K., Reindl, M., Klimaschewski, L., Poewe, W., Wenning, G. K., & Stefanova, N. (2013) · Glia · doi:10.1002/glia.22437 · Cited by 697 · see citing works

Extracellular Matrix: Functions in the Nervous System

Barros, C. S., Franco, S. J., & Muller, U. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005108 · Cited by 506 · see citing works

Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity

Sorg, B. A., Berretta, S., Blacktop, J. M., Fawcett, J. W., Kitagawa, H., Kwok, J. C. F., & Miquel, M. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.2351-16.2016 · Cited by 454 · see citing works

Glia: Initiators and progressors of pathology in Parkinson's disease

Halliday, G. M., & Stevens, C. H. (2011) · Movement Disorders · doi:10.1002/mds.23455 · Cited by 423 · see citing works

SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions

Sun, W., Cornwell, A., Li, J., Peng, S., Osorio, M. J., Aalling, N., Wang, S., Benraiss, A., Lou, N., Goldman, S. A., et al. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.3199-16.2017 · Cited by 357 · see citing works

Molecular signals of plasticity at the tetrapartite synapse

Dityatev, A., & Rusakov, D. A. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.12.006 · Cited by 267 · see citing works

Astrocytes as a Source for Extracellular Matrix Molecules and Cytokines

Wiese, S., Karus, M., & Faissner, A. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00120 · Cited by 262 · see citing works

Astroglial cradle in the life of the synapse

Verkhratsky, A., & Nedergaard, M. (2014) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2013.0595 · Cited by 266 · see citing works

Targeting the neural extracellular matrix in neurological disorders

Soleman, S., Filippov, M. A., Dityatev, A., & Fawcett, J. W. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.08.050 · Cited by 244 · see citing works

Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain

Dityatev, A. E., Seidenbecher, C. I., & Schachner, M. (2010) · Trends in Neurosciences · doi:10.1016/j.tins.2010.08.003 · Cited by 229 · see citing works

The Medium of Haptic Perception: A Tensegrity Hypothesis

Turvey, M. T., & Fonseca, S. T. (2014) · Journal of Motor Behavior · doi:10.1080/00222895.2013.798252 · Cited by 235 · see citing works

The brain interstitial system: Anatomy, modeling, in vivo measurement, and applications

Lei, Y., Han, H., Yuan, F., Javeed, A., & Zhao, Y. L. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.12.007 · Cited by 215 · see citing works

Extracellular matrix abnormalities in schizophrenia

Berretta, S. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.08.010 · Cited by 179 · see citing works

Microglia as hackers of the matrix: sculpting synapses and the extracellular space

Crapser, J. D., Arreola, M. A., Tsourmas, K. I., & Green, K. N. (2021) · Cellular & Molecular Immunology · doi:10.1038/s41423-021-00751-3 · Cited by 178 · see citing works

Shaping Synapses by the Neural Extracellular Matrix

Ferrer-Ferrer, M., & Dityatev, A. (2018) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2018.00040 · Cited by 169 · see citing works

Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts

Fellner, L., Jellinger, K. A., Wenning, G. K., & Stefanova, N. (2011) · Acta Neuropathologica · doi:10.1007/s00401-011-0833-z · Cited by 162 · see citing works

Neurons associated with aggrecan-based perineuronal nets are protected against tau pathology in subcortical regions in Alzheimer's disease

Morawski, M., Brückner, G., Jäger, C., Seeger, G., & Arendt, T. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.05.022 · Cited by 156 · see citing works

Aggrecan and chondroitin-6-sulfate abnormalities in schizophrenia and bipolar disorder: a postmortem study on the amygdala

Pantazopoulos, H., Markota, M., Jaquet, F., Ghosh, D., Wallin, A., Santos, A., Caterson, B., & Berretta, S. (2015) · Translational Psychiatry · doi:10.1038/tp.2014.128 · Cited by 153 · see citing works

The Brain’s Extracellular Matrix and Its Role in Synaptic Plasticity

Frischknecht, R., & Gundelfinger, E. D. (2012) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-7091-0932-8_7 · Cited by 156 · see citing works

Losing the sugar coating: Potential impact of perineuronal net abnormalities on interneurons in schizophrenia

Berretta, S., Pantazopoulos, H., Markota, M., Brown, C., & Batzianouli, E. T. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2014.12.040 · Cited by 152 · see citing works

Morphological plasticity of astroglia: Understanding synaptic microenvironment

Heller, J. P., & Rusakov, D. A. (2015) · Glia · doi:10.1002/glia.22821 · Cited by 150 · see citing works

Primary Hippocampal Neurons, Which Lack Four Crucial Extracellular Matrix Molecules, Display Abnormalities of Synaptic Structure and Function and Severe Deficits in Perineuronal Net Formation

Geissler, M., Gottschling, C., Aguado, A., Rauch, U., Wetzel, C. H., Hatt, H., & Faissner, A. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3275-12.2013 · Cited by 140 · see citing works

Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats

Riga, D., Kramvis, I., Koskinen, M. K., van Bokhoven, P., van der Harst, J. E., Heistek, T. S., Jaap Timmerman, A., van Nierop, P., van der Schors, R. C., Pieneman, A. W., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aai8753 · Cited by 128 · see citing works

Converting juvenile into adult plasticity: a role for the brain's extracellular matrix

Gundelfinger, E. D., Frischknecht, R., Choquet, D., & Heine, M. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07253.x · Cited by 136 · see citing works

Neuron-Glia Interactions in Neural Plasticity: Contributions of Neural Extracellular Matrix and Perineuronal Nets

Dzyubenko, E., Gottschling, C., & Faissner, A. (2016) · Neural Plasticity · doi:10.1155/2016/5214961 · Cited by 134 · see citing works

Chondroitin sulfate proteoglycans regulate astrocyte‐dependent synaptogenesis and modulate synaptic activity in primary embryonic hippocampal neurons

Pyka, M., Wetzel, C., Aguado, A., Geissler, M., Hatt, H., & Faissner, A. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07690.x · Cited by 131 · see citing works

Extracellular matrix molecules, their receptors, and secreted proteases in synaptic plasticity

Włodarczyk, J., Mukhina, I. V., Kaczmarek, L., & Dityatev, A. E. (2011) · Developmental Neurobiology · doi:10.1002/dneu.20958 · Cited by 123 · see citing works

Elimination of the four extracellular matrix molecules tenascin-C, tenascin-R, brevican and neurocan alters the ratio of excitatory and inhibitory synapses

Gottschling, C., Wegrzyn, D., Denecke, B., & Faissner, A. (2019) · Scientific Reports · doi:10.1038/s41598-019-50404-9 · Cited by 111 · see citing works

In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders

Pantazopoulos, H., & Berretta, S. (2015) · Neural Plasticity · doi:10.1155/2016/9847696 · Cited by 118 · see citing works

The Interstitial System of the Brain in Health and Disease

Shetty, A. K., & Zanirati, G. (2020) · Aging and Disease · doi:10.14336/ad.2020.0103 · Cited by 114 · see citing works

Cell adhesion and matricellular support by astrocytes of the tripartite synapse

Hillen, A. E. J., Burbach, J. P. H., & Hol, E. M. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.02.002 · Cited by 108 · see citing works

The Extracellular Environment of the CNS: Influence on Plasticity, Sprouting, and Axonal Regeneration after Spinal Cord Injury

Quraishe, S., Forbes, L. H., & Andrews, M. R. (2018) · Neural Plasticity · doi:10.1155/2018/2952386 · Cited by 105 · see citing works

Synapse formation on adult‐born hippocampal neurons

Toni, N., & Sultan, S. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07604.x · Cited by 101 · see citing works

Phenotypic and gene expression modification with normal brain aging in GFAP-positive astrocytes and neural stem cells

Bernal, G. M., & Peterson, D. A. (2011) · Aging Cell · doi:10.1111/j.1474-9726.2011.00694.x · Cited by 102 · see citing works

Chondroitin Sulfate “Wobble Motifs” Modulate Maintenance and Differentiation of Neural Stem Cells and Their Progeny

Purushothaman, A., Sugahara, K., & Faissner, A. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.r111.298430 · Cited by 101 · see citing works

Colocalization of synapse marker proteins evaluated by STED-microscopy reveals patterns of neuronal synapse distribution in vitro

Dzyubenko, E., Rozenberg, A., Hermann, D. M., & Faissner, A. (2016) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2016.09.001 · Cited by 98 · see citing works

The enigmatic fetal subplate compartment forms an early tangential cortical nexus and provides the framework for construction of cortical connectivity

Kostović, I. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101883 · Cited by 102 · see citing works

Dysregulation of astrocyte extracellular signaling in Costello syndrome

Krencik, R., Hokanson, K. C., Narayan, A. R., Dvornik, J., Rooney, G. E., Rauen, K. A., Weiss, L. A., Rowitch, D. H., & Ullian, E. M. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa5645 · Cited by 90 · see citing works

Tenascin-C in the matrisome of neural stem and progenitor cells

Faissner, A., Roll, L., & Theocharidis, U. (2016) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2016.11.003 · Cited by 89 · see citing works

Memristive Circuit Implementation of a Self-Repairing Network Based on Biological Astrocytes in Robot Application

Hong, Q., Chen, H., Sun, J., & Wang, C. (2020) · IEEE Transactions on Neural Networks and Learning Systems · doi:10.1109/tnnls.2020.3041624 · Cited by 85 · see citing works

Myelination

Barnett, S. C., & Linington, C. (2012) · The Neuroscientist · doi:10.1177/1073858412465655 · Cited by 83 · see citing works

Neural Functions of Matrix Metalloproteinases: Plasticity, Neurogenesis, and Disease

Fujioka, H., Dairyo, Y., Yasunaga, K.-I., & Emoto, K. (2012) · Biochemistry Research International · doi:10.1155/2012/789083 · Cited by 81 · see citing works

The extracellular matrix molecule tenascin C modulates expression levels and territories of key patterning genes during spinal cord astrocyte specification

Karus, M., Denecke, B., ffrench‐Constant, C., Wiese, S., & Faissner, A. (2011) · Development · doi:10.1242/dev.067413 · Cited by 80 · see citing works

Developmental disruption of perineuronal nets in the medial prefrontal cortex after maternal immune activation

Paylor, J. W., Lins, B. R., Greba, Q., Moen, N., de Moraes, R. S., Howland, J. G., & Winship, I. R. (2016) · Scientific Reports · doi:10.1038/srep37580 · Cited by 79 · see citing works

Extracellular Matrix in Neural Plasticity and Regeneration

Chelyshev, Y. A., Kabdesh, I. M., & Mukhamedshina, Y. O. (2020) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-00986-0 · Cited by 76 · see citing works

Signaling pathways regulating neuron–glia interaction and their implications in Alzheimer's disease

Lian, H., & Zheng, H. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13424 · Cited by 75 · see citing works

Collective timekeeping among cells of the master circadian clock

Evans, J. A. (2016) · Journal of Endocrinology · doi:10.1530/joe-16-0054 · Cited by 77 · see citing works

Neuronal CC chemokines: the distinct roles of CCL21 and CCL2 in neuropathic pain

Biber, K. P. H., & Boddeke, E. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00210 · Cited by 72 · see citing works

Proteomics of the Synapse – A Quantitative Approach to Neuronal Plasticity

Dieterich, D. C., & Kreutz, M. R. (2015) · Molecular & Cellular Proteomics · doi:10.1074/mcp.r115.051482 · Cited by 73 · see citing works

Keratan sulfate ( KS )‐proteoglycans and neuronal regulation in health and disease: the importance of KS ‐glycodynamics and interactive capability with neuroregulatory ligands

Melrose, J. (2018) · Journal of Neurochemistry · doi:10.1111/jnc.14652 · Cited by 71 · see citing works

Low Density Receptor-Related Protein 1 Interactions With the Extracellular Matrix: More Than Meets the Eye

Bres, E. E., & Faissner, A. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00031 · Cited by 67 · see citing works

Sublaminar organization of the human subplate: developmental changes in the distribution of neurons, glia, growing axons and extracellular matrix

Kostović, I., Išasegi, I. Ž., & Krsnik, Ž. (2018) · Journal of Anatomy · doi:10.1111/joa.12920 · Cited by 67 · see citing works

Lectican proteoglycans, their cleaving metalloproteinases, and plasticity in the central nervous system extracellular microenvironment

Howell, M. D., & Gottschall, P. E. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.05.034 · Cited by 66 · see citing works

Glial Cells and Integrity of the Nervous System

von Bernhardi, R., Eugenín-von Bernhardi, J., Flores, B., & Eugenín León, J. (2016) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-319-40764-7_1 · Cited by 67 · see citing works

Roles of glial cells in schizophrenia: Possible targets for therapeutic approaches

Takahashi, N., & Sakurai, T. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.11.001 · Cited by 67 · see citing works

Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research

Engel, M., Do‐Ha, D., Muñoz, S. S., & Ooi, L. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2265-3 · Cited by 67 · see citing works

Targeting of ECM molecules and their metabolizing enzymes and receptors for the treatment of CNS diseases

Berezin, V., Walmod, P. S., Filippov, M. A., & Dityatev, A. E. (2014) · Progress in brain research · doi:10.1016/b978-0-444-63486-3.00015-3 · Cited by 62 · see citing works

Synapses between NG2 glia and neurons

Sakry, D., Karram, K., & Trotter, J. (2011) · Journal of Anatomy · doi:10.1111/j.1469-7580.2011.01359.x · Cited by 60 · see citing works

SynProt: A Database for Proteins of Detergent-Resistant Synaptic Protein Preparations

Pielot, R., Smalla, K., Müller, A., Landgraf, P., Lehmann, A., Eisenschmidt, E., Haus, U., Weismantel, R., Gundelfinger, E. D., & Dieterich, D. C. (2012) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2012.00001 · Cited by 60 · see citing works

Laminin-derived Ile-Lys-Val-ala-Val: a promising bioactive peptide in neural tissue engineering in traumatic brain injury

Negah, S. S., khooei, A. T., Samini, F., & Gorji, A. (2017) · Cell and Tissue Research · doi:10.1007/s00441-017-2717-6 · Cited by 59 · see citing works

Cortical maps: a role for astrocytes?

López-Hidalgo, M. A., & Schummers, J. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.11.001 · Cited by 56 · see citing works

Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus

Krzisch, M., Temprana, S. G., Mongiat, L. A., Armida, J., Schmutz, V., Virtanen, M. A., Kocher-Braissant, J., Kraftsik, R., Vutskits, L., Conzelmann, K.-K., et al. (2015) · Brain Structure and Function · doi:10.1007/s00429-014-0768-y · Cited by 57 · see citing works

The blood–brain barrier and beyond: Nano-based neuropharmacology and the role of extracellular matrix

Henrich‐Noack, P., Nikitovic, D., Neagu, M. T., Docea, A. O., Engin, A. B., Gelperina, S. E., Штильман, М. И., Mitsias, P. D., Tzanakakis, G. N., Gozes, I., et al. (2019) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2019.01.016 · Cited by 57 · see citing works

Extracellular matrix remodeling during retinal development

Reinhard, J., Joachim, S. C., & Faissner, A. (2014) · Experimental Eye Research · doi:10.1016/j.exer.2014.07.001 · Cited by 56 · see citing works

Profiling changes in cortical astroglial cells following chronic stress

Simard, S., Coppola, G., Rudyk, C., Hayley, S. P., McQuaid, R. J., & Salmaso, N. (2018) · Neuropsychopharmacology · doi:10.1038/s41386-018-0105-x · Cited by 58 · see citing works

Incubation of depression: ECM assembly and parvalbumin interneurons after stress

Spijker, S., Koskinen, M.-K., & Riga, D. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.07.015 · Cited by 55 · see citing works

Influence of the extracellular matrix on endogenous and transplanted stem cells after brain damage

Roll, L., & Faissner, A. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00219 · Cited by 54 · see citing works

Tenascins in CNS lesions

Roll, L., & Faissner, A. (2018) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2018.09.012 · Cited by 54 · see citing works

Decreased Density of Perineuronal Net in Prelimbic Cortex Is Linked to Depressive-Like Behavior in Young-Aged Rats

Yu, Z., Chen, N., Hu, D., Chen, W., Yuan, Y., Meng, S., Zhang, W., Lu, L., Han, Y., & Shi, J. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2020.00004 · Cited by 52 · see citing works

Long-term effects of ionising radiation on the brain: cause for concern?

Kempf, S. J., Azimzadeh, O., Atkinson, M. J., & Tapio, S. (2012) · Radiation and Environmental Biophysics · doi:10.1007/s00411-012-0436-7 · Cited by 52 · see citing works

Role of immune responses for extracellular matrix remodeling in the ischemic brain

Dzyubenko, E., Manrique‐Castano, D., Kleinschnitz, C., Faissner, A., & Hermann, D. M. (2018) · Therapeutic Advances in Neurological Disorders · doi:10.1177/1756286418818092 · Cited by 55 · see citing works

Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor fasudil reveals cytoskeletal and pro-survival responses

Lau, C. L., Perreau, V. M., Chen, M. J., Cate, H. S., Merlo, D., Cheung, N. S., O'Shea, R. D., & Beart, P. M. (2012) · Journal of Cellular Physiology · doi:10.1002/jcp.22838 · Cited by 49 · see citing works

Bioenergetic medicine

Swerdlow, R. H. (2013) · British Journal of Pharmacology · doi:10.1111/bph.12394 · Cited by 50 · see citing works

Review of Design Considerations for Brain-on-a-Chip Models

Cameron, T., Bennet, T. J., Rowe, E. M., Anwer, M., Wellington, C. L., & Cheung, K. C. (2021) · Micromachines · doi:10.3390/mi12040441 · Cited by 48 · see citing works

Integrating GWAS and Transcriptomics to Identify the Molecular Underpinnings of Thermal Stress Responses in Drosophila melanogaster

Lecheta, M. C., Awde, D. N., O’Leary, T. S., Unfried, L. N., Jacobs, N. A., Whitlock, M. H., McCabe, E. A., Powers, B., Bora, K., Waters, J. S., et al. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00658 · Cited by 47 · see citing works

Valproic acid mediates the synaptic excitatory/inhibitory balance through astrocytes — A preliminary study

Wang, C.-C., Chen, P. S., Hsu, C.-W., Wu, S.-J., Lin, C.-T., & Gean, P. W. (2012) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.01.017 · Cited by 47 · see citing works

Regulation of IL-6 secretion by astrocytes via TLR4 in the fragile X mouse model.

Krasovska, V., & Doering, L. C. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00272 · Cited by 47 · see citing works

Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway

Gao, W., Li, B., Chen, X. D., Xiao, J.-W., Cao, P., Zhang, Y., Cai, W.-J., & Song, J. (2020) · Neural Regeneration Research · doi:10.4103/1673-5374.286976 · Cited by 46 · see citing works

Behavioral sequelae of astrocyte dysfunction: focus on animal models of schizophrenia

Xia, M., Abazyan, S., Jouroukhin, Y., & Pletnikov, M. V. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.10.044 · Cited by 46 · see citing works

Dendritic spines of the medial amygdala: plasticity, density, shape, and subcellular modulation by sex steroids.

Rasia‐Filho, A. A., Dalpian, F., Menezes, I. C., Brusco, J., Moreira, J. E., & Cohen, R. S. (2012) · PubMed · doi:10.14670/hh-27.985 · Cited by 45 · see citing works

α‑synuclein induces apoptosis of astrocytes by causing dysfunction of the endoplasmic reticulum‑Golgi compartment

Liu, M., Qin, L., Wang, L., Tan, J., Zhang, H., Tang, J., Shen, X., Tan, L., & Wang, C. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9002 · Cited by 45 · see citing works

Dopamine Receptor Activation Modulates the Integrity of the Perisynaptic Extracellular Matrix at Excitatory Synapses

Mitlöhner, J., Kaushik, R., Niekisch, H., Blondiaux, A., Gee, C. E., Happel, M. F. K., Gundelfinger, E., Dityatev, A., Frischknecht, R., & Seidenbecher, C. (2020) · Cells · doi:10.3390/cells9020260 · Cited by 47 · see citing works

Role of astrocytic glutamate transporter in alcohol use disorder

Ayers-Ringler, J. R., Jia, Y., Qiu, Y., & Choi, D. (2016) · World Journal of Psychiatry · doi:10.5498/wjp.v6.i1.31 · Cited by 43 · see citing works

Roles of Glial Cells in Sculpting Inhibitory Synapses and Neural Circuits

Um, J. W. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00381 · Cited by 44 · see citing works

Neural ECM and synaptogenesis

Heikkinen, A., Pihlajaniemi, T., Faissner, A., & Yuzaki, M. (2014) · Progress in Brain Research · doi:10.1016/b978-0-444-63486-3.00002-5 · Cited by 42 · see citing works

Astrocytes are crucial for survival and maturation of embryonic hippocampal neurons in a neuron‐glia cell‐insert coculture assay

Pyka, M., Busse, C., Seidenbecher, C. I., Gundelfinger, E. D., & Faissner, A. (2010) · Synapse · doi:10.1002/syn.20816 · Cited by 41 · see citing works

Testican‐3: a brain‐specific proteoglycan member of the BM ‐40/ SPARC /osteonectin family

Hartmann, U., Hülsmann, H., Seul, J., Röll, S., Midani-Özkan, H., Breloy, I., Hechler, D., Müller, R., & Paulsson, M. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12212 · Cited by 41 · see citing works

The multifaceted role of metalloproteinases in physiological and pathological conditions in embryonic and adult brains

Stefano, M. E. D., & Herrero, M. T. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.08.002 · Cited by 42 · see citing works

Resveratrol extends lifespan and preserves glia but not neurons of the Nothobranchius guentheri optic tectum

Genade, T., & Lang, D. M. (2012) · Experimental Gerontology · doi:10.1016/j.exger.2012.11.013 · Cited by 40 · see citing works

Emerging themes in GABAergic synapse development

Kuzirian, M. S., & Paradis, S. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.07.002 · Cited by 39 · see citing works

Matrix Metalloproteinases, Neural Extracellular Matrix, and Central Nervous System Pathology

Luca, C. D., & Papa, M. (2017) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2017.04.002 · Cited by 39 · see citing works

Neurocan regulates vulnerability to stress and the anti-depressant effect of ketamine in adolescent rats

Yu, Z., Han, Y., Hu, D., Chen, N., Zhang, Z., Chen, W., Xue, Y.-X., Meng, S., Lü, L., Zhang, W., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01495-w · Cited by 37 · see citing works

Human dermal fibroblasts in psychiatry research

Kalman, J. L., Garbett, K. A., Janka, Z., & Mirnics, K. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.01.067 · Cited by 38 · see citing works

Perineuronal nets as regulators of parvalbumin interneuron function: Factors implicated in their formation and degradation

Santos‐Silva, T., Colodete, D. A. E., Lisboa, J. R., Freitas, I. D. S., Lopes, C. F. B., Hadera, V., Lima, T. S. A., Souza, A. J., & Gomes, F. V. (2024) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.13994 · Cited by 36 · see citing works

Brevican, Neurocan, Tenascin-C, and Tenascin-R Act as Important Regulators of the Interplay Between Perineuronal Nets, Synaptic Integrity, Inhibitory Interneurons, and Otx2

Mueller-Buehl, C., Reinhard, J., Roll, L., Bader, V., Winklhofer, K. F., & Faissner, A. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.886527 · Cited by 35 · see citing works

A new indirect co-culture set up of mouse hippocampal neurons and cortical astrocytes on microelectrode arrays

Geißler, M., & Faissner, A. (2011) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2011.11.030 · Cited by 36 · see citing works

The role of extracellular matrix in spinal cord development

Wiese, S., & Faissner, A. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.05.018 · Cited by 35 · see citing works

Loss of Interneuron-Derived Collagen XIX Leads to a Reduction in Perineuronal Nets in the Mammalian Telencephalon

Su, J., Cole, J., & Fox, M. A. (2017) · ASN NEURO · doi:10.1177/1759091416689020 · Cited by 33 · see citing works

Neuron-Glia Interactions in Neural Plasticity: Contributions of Neural Extracellular Matrix and Perineuronal Nets

Dzyubenko, E., Gottschling, C., & Faissner, A. (2016) · Neural Plasticity · doi:10.1155/2016/5214961 · Cited by 134 · see citing works

Neuron-glia interactions in neural plasticity

Dzyubenko, E., Gottschling, C., & Faissner, A. (2016) · Dokumentenrepositorium der RUB (Ruhr University Bochum)

Development/Plasticity/Repair Primary Hippocampal Neurons, Which Lack Four Crucial Extracellular Matrix Molecules, Display Abnormalities of Synaptic Structure and Function and Severe Deficits in Perineuronal Net Formation

Faissner, A. (2016)

Chondroitin sulfate proteoglycans regulate astrocyte‐dependent synaptogenesis and modulate synaptic activity in primary embryonic hippocampal neurons

Pyka, M., Wetzel, C., Aguado, A., Geissler, M., Hatt, H., & Faissner, A. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07690.x · Cited by 131 · see citing works

Primary Hippocampal Neurons, Which Lack Four Crucial Extracellular Matrix Molecules, Display Abnormalities of Synaptic Structure and Function and Severe Deficits in Perineuronal Net Formation

Geissler, M., Gottschling, C., Aguado, A., Rauch, U., Wetzel, C. H., Hatt, H., & Faissner, A. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3275-12.2013 · Cited by 140 · see citing works