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Death squads enlisted by the tumour suppressor p53
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“Both pathways are regulated by p53 [58].”
From The TP53 tumor suppressor gene: From molecular biology to clinical investigations (2025) · cites this paper as [58]
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Danial, N. N., & Korsmeyer, S. J. (2004) · Cell · doi:10.1016/s0092-8674(04)00046-7 · Cited by 4,651
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
Toshiyuki, M., & Reed, J. C. (1995) · Cell · doi:10.1016/0092-8674(95)90412-3 · Cited by 4,063
p53 is required for radiation-induced apoptosis in mouse thymocytes
Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A., & Jacks, T. (1993) · Nature · doi:10.1038/362847a0 · Cited by 2,864
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.
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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
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Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
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Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis
Chipuk, J. E., Kuwana, T., Bouchier-Hayes, L., Droin, N. M., Newmeyer, D. D., Schuler, M., & Green, D. R. (2004) · Science · doi:10.1126/science.1092734 · Cited by 2,108 · cited 1×
“There is also emerging evidence that the p53 protein may bind directly to the BAX protein and thereby induce apoptosis through a transcription-independent mechanism [101].”
Lindsten, T., Ross, A. J., King, A., Zong, W.-X., Rathmell, J. C., Shiels, H. A., Ulrich, E., Waymire, K. G., Mahar, P., Frauwirth, K., et al. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00136-2 · Cited by 1,489
Triggering and modulation of apoptosis by oxidative stress
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Self-citation
Metadata
- Authors
- Michalak, E., Villunger, A., Erlacher, M., & Strasser, A.
- Venue
- Biochemical and Biophysical Research Communications
- Publisher
- Elsevier BV
- Published
- 2005-06
- Volume
- 331
- Issue
- 3
- Pages
- 786-798
- ISSN
- 0006-291X
- Cited by
- 94
- References
- 21
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
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Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Death squads enlisted by the tumour suppressor p53. https://app.cochat.ai/papers/10.1016/j.bbrc.2005.03.183
- The paper
- Michalak, E., Villunger, A., Erlacher, M., & Strasser, A. (2005). Death squads enlisted by the tumour suppressor p53. Biochemical and Biophysical Research Communications. https://doi.org/10.1016/j.bbrc.2005.03.183
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.