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M2 macrophage-derived exosomes promote diabetic fracture healing by acting as an immunomodulator

Wang, Yili, Lin, Qiushui, Zhang, Hao, Wang, Sicheng, Cui, Jin, Hu, Yan, Liu, Jinlong, Li, Mengmeng, Zhang, Kun, Zhou, Fengjin, Jing, Yingying, Geng, Zhen, Su, Jiacan·2023·Bioactive Materials
DOI 10.1016/j.bioactmat.2023.05.018PMC PMC10247878
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  • Clinical management often fails to address the combined effects of DM-induced chronic inflammation and acute inflammation triggered by bone injury, leading to disrupted macrophage polarization and immune dysregulation that hinder bone repair.

    “Furthermore, clinical management often fails to address the combined effects of DM-induced chronic inflammation and acute inflammation triggered by bone injury, leading to disrupted macrophage polarization and immune dysregulation, which further hinder bone repair11.”

    From Microenvironment-responsive multifunctional enzyme-linked hydrogel for diabetic bone defect regeneration. (2025) · cites this paper as [11]

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Research works printed but not linked: 45

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Metadata

Authors
Wang, Y., Lin, Q., Zhang, H., Wang, S., Cui, J., Hu, Y., Liu, J., Li, M., Zhang, K., Zhou, F., Jing, Y., Geng, Z., & Su, J.
ORCID
Venue
Bioactive Materials
Publisher
Elsevier BV
Published
2023-10
Volume
28
Pages
273-283
ISSN
2452-199X
DOI
10.1016/j.bioactmat.2023.05.018
PMC
PMC10247878
Cited by
98
References
5
Language
en
Licence
Funders
National Natural Science Foundation of China (32101084, 82202344, 82230071, 92249303)

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