Mechanisms of chaperone-mediated autophagy

Molecular dissection of autophagy: two ubiquitin-like systems

Ohsumi, Y. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35056522 · Cited by 1,240

Cathepsin A regulates chaperone‐mediated autophagy through cleavage of the lysosomal receptor

Cuervo, A. M., Mann, L., Bonten, E. J., d'Azzo, A., & Dice, J. F. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg002 · Cited by 182

Autophagy and aging: The importance of maintaining "clean" cells

Cuervo, A. M., Bergamini, E., Brunk, U. T., Dröge, W., Ffrench, M., & Terman, A. (2005) · Autophagy · doi:10.4161/auto.1.3.2017 · Cited by 792

Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells

Vogiatzi, T., Xilouri, M., Vekrellis, K., & Stefanis, L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801992200 · Cited by 683

Methods for Monitoring Autophagy from Yeast to Human

Klionsky, D. J., Cuervo, A. M., & Seglen, P. O. (2007) · Autophagy · doi:10.4161/auto.3678 · Cited by 656

Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes.

Schmid, D., Pypaert, M., & Münz, C. (2007) · Immunity · doi:10.1016/j.immuni.2006.10.018 · Cited by 577

Consequences of the selective blockage of chaperone-mediated autophagy

Massey, A. C., Kaushik, S., Sovak, G., Kiffin, R., & Cuervo, A. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507436103 · Cited by 529

GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

Colell, A., Ricci, J.-E., Tait, S., Milasta, S., Maurer, U., Bouchier-Hayes, L., Fitzgerald, P., Guio-Carrion, A., Waterhouse, N. J., Li, C. W., et al. (2007) · Cell · doi:10.1016/j.cell.2007.03.045 · Cited by 516

Lipofuscin: Formation, Distribution, and Metabolic Consequences

JUNG, T., BADER, N., & GRUNE, T. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1404.008 · Cited by 415

Chaperone-mediated autophagy in aging and disease

Massey, A. C., Zhang, C., & Cuervo, A. M. (2006) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(05)73007-6 · Cited by 315

Pharmacological and toxicological target organelles and safe use of single-walled carbon nanotubes as drug carriers in treating alzheimer disease.

Yang, Z., Zhang, Y., Yang, Y., Sun, L., Han, D., Li, H., & Wang, C. (2010) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2009.11.007 · Cited by 311

Role of DJ-1 in the mechanism of pathogenesis of Parkinson's disease

Dolgacheva, L. P., Berezhnov, A. V., Fedotova, E. I., Zinchenko, V. P., & Abramov, A. Y. (2019) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-019-09798-4 · Cited by 254

Aberrant Interaction between Parkinson Disease-associated Mutant UCH-L1 and the Lysosomal Receptor for Chaperone-mediated Autophagy

Kabuta, T., Furuta, A., Aoki, S., Furuta, K., & Wada, K. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801918200 · Cited by 227

Autophagy in Alzheimer’s disease

Zare-shahabadi, A., Masliah, E., Johnson, G. V. W., & Rezaei, N. (2015) · Reviews in the Neurosciences · doi:10.1515/revneuro-2014-0076 · Cited by 204

Ordered Organelle Degradation during Starvation-induced Autophagy

Kristensen, A. R., Schandorff, S., Høyer-Hansen, M., Nielsen, M. O., Jaüaüttelaü, M., Dengjel, J., & Andersen, J. S. (2008) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m800184-mcp200 · Cited by 165

Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)

Qing, G., Yan, P., & Xiao, G. (2006) · Cell Research · doi:10.1038/sj.cr.7310109 · Cited by 140

Neuronal autophagy: a housekeeper or a fighter in neuronal cell survival?

Lee, J.-A. (2012) · Experimental Neurobiology · doi:10.5607/en.2012.21.1.1 · Cited by 119

Chaperone-mediated autophagy. Machinery, regulation and biological consequences

Li, W., Yang, Q., & Mao, Z. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0565-6 · Cited by 119

Pathogenic Mechanisms of Neurodegeneration in Parkinson Disease

Mullin, S., & Schapira, A. H. V. (2015) · Neurologic Clinics · doi:10.1016/j.ncl.2014.09.010 · Cited by 108

Essential control of mitochondrial morphology and function by chaperone-mediated autophagy through degradation of PARK7

Wang, B., Cai, Z., Tao, K., Zeng, W., Lu, F., Yang, R., Feng, D., Gao, G., & Yang, Q. (2016) · Autophagy · doi:10.1080/15548627.2016.1179401 · Cited by 107

microRNAs as neuroregulators, biomarkers and therapeutic agents in neurodegenerative diseases

Basak, I., Patil, K. S., Alves, G., Larsen, J. P., & Møller, S. G. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2093-x · Cited by 107

TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy

Alquezar, C., Schoch, K. M., Geier, E. G., Ramos, E. M., Scrivo, A., Li, K. H., Argouarch, A. R., Mlynarski, E. E., Dombroski, B., DeTure, M., et al. (2021) · Science Advances · doi:10.1126/sciadv.abg3897 · Cited by 56

Basal autophagy induction without AMP-activated protein kinase under low glucose conditions

Williams, T., Forsberg, L. J., Viollet, B., & Brenman, J. E. (2009) · Autophagy · doi:10.4161/auto.5.8.10090 · Cited by 42

Hsp70 inhibition induces myeloma cell death via the intracellular accumulation of immunoglobulin and the generation of proteotoxic stress

Zhang, L., Fok, J. J. L., Mirabella, F., Aronson, L. I., Fryer, R. A., Workman, P., Morgan, G. J., & Davies, F. E. (2013) · Cancer Letters · doi:10.1016/j.canlet.2013.07.023 · Cited by 32