Bile acids: From digestion to cancers

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

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Bile salt biotransformations by human intestinal bacteria

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Identification of a nuclear receptor for bile acids

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Nonalcoholic Fatty Liver, Steatohepatitis, and the Metabolic Syndrome

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NF-κB functions as a tumour promoter in inflammation-associated cancer

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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

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The Enzymes, Regulation, and Genetics of Bile Acid Synthesis

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Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production

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The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

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TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

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Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis

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Liver fibrosis – from bench to bedside

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Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

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A G Protein-coupled Receptor Responsive to Bile Acids

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Molecular Basis for Feedback Regulation of Bile Acid Synthesis by Nuclear Receptors

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Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

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Vitamin D Receptor As an Intestinal Bile Acid Sensor

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Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

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Bile salt transporters: molecular characterization, function, and regulation

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Identification of membrane-type receptor for bile acids (M-BAR)

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Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

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Farnesoid X receptor is essential for normal glucose homeostasis

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Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

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Human Bile Salt Export Pump Promoter Is Transactivated by the Farnesoid X Receptor/Bile Acid Receptor

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Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

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The bile acid receptor FXR is a modulator of intestinal innate immunity

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Nuclear Receptor-Dependent Bile Acid Signaling Is Required for Normal Liver Regeneration

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Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response

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The Farnesoid X Receptor

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Bile Acid Transporters: Structure, Function, Regulation and Pathophysiological Implications

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The G-Protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) in mice

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Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor

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Bile Acids Regulate Gluconeogenic Gene Expression via Small Heterodimer Partner-mediated Repression of Hepatocyte Nuclear Factor 4 and Foxo1

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Identification of a Bile Acid-responsive Element in the Human Ileal Bile Acid-binding Protein Gene

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Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea

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Farnesoid X Receptor Responds to Bile Acids and Represses Cholesterol 7α-Hydroxylase Gene (CYP7A1) Transcription

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Nuclear Bile Acid Receptor FXR Protects against Intestinal Tumorigenesis

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Enterohepatic Circulation of Bile Salts in Farnesoid X Receptor-deficient Mice

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The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-α and -β genes

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