Cited by 630Nerve injury and regenerationTissue Engineering and Regenerative MedicineNeuroscience and Neural Engineering

The DOI matches its Crossref record; 280 of the 280 references it cites were found in a registry or an index.

Neural tissue engineering options for peripheral nerve regeneration

Gu, Xiaosong, Ding, Fei, Williams, David F.·2014·Biomaterials

DOI 10.1016/j.biomaterials.2014.04.064

Open this paper in CoChat — free account

Abstract

Tissue engineered nerve grafts (TENGs) have emerged as a potential alternative to autologous nerve grafts, the gold standard for peripheral nerve repair. Typically, TENGs are composed of a biomaterial-based template that incorporates biochemical cues. A number of TENGs have been used experimentally to bridge long peripheral nerve gaps in various animal models, where the desired outcome is nerve tissue regeneration and functional recovery. So far, the translation of TENGs to the clinic for use in humans has met with a certain degree of success. In order to optimize the TENG design and further approach the matching of TENGs with autologous nerve grafts, many new cues, beyond the traditional ones, will have to be integrated into TENGs. Furthermore, there is a strong requirement for monitoring the real-time dynamic information related to the construction of TENGs. The aim of this opinion paper is to specifically and critically describe the latest advances in the field of neural tissue engineering for peripheral nerve regeneration. Here we delineate new attempts in the design of template (or scaffold) materials, especially in the context of biocompatibility, the choice and handling of support cells, and growth factor release systems. We further discuss the significance of RNAi for peripheral nerve regeneration, anticipate the potential application of RNAi reagents for TENGs, and speculate on the possible contributions of additional elements, including angiogenesis, electrical stimulation, molecular inflammatory mediators, bioactive peptides, antioxidant reagents, and cultured biological constructs, to TENGs. Finally, we consider that a diverse array of physicochemical and biological cues must be orchestrated within a TENG to create a self-consistent coordinated system with a close proximity to the regenerative microenvironment of the peripheral nervous system.

Integrity signals

Registry

Crossref · 10.1016/j.biomaterials.2014.04.064

Cites

280 of 280 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

1 retracted

Enhancement of regeneration with glia cell line–derived neurotrophic factor–transduced human amniotic fluid mesenchymal stem cells after sciatic nerve crush injury [RETRACTED]
Cheng, F., Tai, M., Sheu, M., Chen, C., Yang, D., Su, H., Ho, S.-P., Lai, S.-Z., & Pan, H.-C. (2009) · Journal of neurosurgery · doi:10.3171/2009.8.jns09850 · Cited by 70
Retracted
MicroRNAs: Target Recognition and Regulatory Functions
Bartel, D. P. (2009) · Cell · doi:10.1016/j.cell.2009.01.002 · Cited by 20,068
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., & Mello, C. C. (1998) · Nature · doi:10.1038/35888 · Cited by 15,429
Most mammalian mRNAs are conserved targets of microRNAs
Friedman, R. C., Farh, K. K.-H., Burge, C. B., & Bartel, D. P. (2009) · Genome Research · doi:10.1101/gr.082701.108 · Cited by 8,462
Knocking down barriers: advances in siRNA delivery
Whitehead, K. A., Langer, R., & Anderson, D. G. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2742 · Cited by 3,115
On the mechanisms of biocompatibility
Williams, D. F. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.04.023 · Cited by 2,772
Self-citation
Long noncoding RNAs: functional surprises from the RNA worldPreprint
Wilusz, J. E., Sunwoo, H., & Spector, D. L. (2009) · Genes & Development · doi:10.1101/gad.1800909 · Cited by 2,322
Bone Marrow Stromal Stem Cells: Nature, Biology, and Potential Applications
Bianco, P., Riminucci, M., Gronthos, S., & Robey, P. G. (2001) · Stem Cells · doi:10.1634/stemcells.19-3-180 · Cited by 1,944
Long noncoding RNAs and human disease
Wapinski, O. L., & Chang, H. Y. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.04.001 · Cited by 1,925
Concise Review: Mesenchymal Stem/Multipotent Stromal Cells: The State of Transdifferentiation and Modes of Tissue Repair—Current Views
Phinney, D. G., & Prockop, D. J. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0637 · Cited by 1,910

Show all 280 references

Sorted by citations

Items 501–600 of 630

Differentiation of Human Adipose-derived Stem Cells to Exosome-affected Neural-like Cells Extracted from Human Cerebrospinal Fluid Using Bioprinting Process
Cheravi, M., Baharara, J., Yaghmaei, P., & Roodbari, N. H. (2023) · Current Stem Cell Research & Therapy · doi:10.2174/011574888x270145231102062259 · Cited by 3
Bioactive Nanomaterials for Neural Engineering
Sever, M., Uyan, İ., Tekinay, A. B., & Guler, M. O. (2016) · Springer eBooks · doi:10.1007/978-3-319-31433-4_6 · Cited by 3
Approaching Human Hand Dexterity Through Highly Biomimetic Design
Xu, Z. Y. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813385-9.00006-6 · Cited by 3
Preparation and characterization of conductive nerve guide conduit filled with dual drug-loaded nanofibers
Yan, X., Yu, Y., Wang, S., Xu, H., He, Q., Wen, J., Xu, J., Li, K., Huang, Z., & Xu, P. (2021) · Journal of Bioactive and Compatible Polymers · doi:10.1177/08839115211053917 · Cited by 3
Biocompatible composite for strain sensor engineering via temperature regulation on single-axial drawing
Zhong, F., Liu, J., Pan, X., Ma, C., Lin, N., & Wang, Z. (2022) · Materials Technology · doi:10.1080/10667857.2022.2072607 · Cited by 3
Recent advances in biomaterials as instructive scaffolds for stem cells in tissue repair and regeneration
Liang, W., Chen, X., Dong, Y., Zhou, P., & Xu, F. (2020) · International Journal of Polymeric Materials · doi:10.1080/00914037.2020.1848832 · Cited by 3
Frontiers of Brachial Plexus Injury: Future Revolutions in the Field
Rosen, J. M., Hong, J., Klaudt-Moreau, J., Podsednik, A., & Hentz, V. R. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.99209 · Cited by 3
Shape‐memory Polymers for Tissue Engineering Applications
Zheng, F., García‐García, A., Moreno, I., Ruiz‐Rubio, L., Pérez‐Álvarez, L., & Vilas‐Vilela, J. L. (2024) · doi:10.1002/9783527838882.ch3 · Cited by 3
Combining PLGA microspheres loaded with Liver X receptor agonist GW3965 with a chitosan nerve conduit can promote the healing and regeneration of the wounded sciatic nerve
Zhong, Y., Li, S., Chen, Y., Tang, Y., Xiao, X., & Nie, T. (2024) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.35378 · Cited by 2
Defensin: The immune system regulatory factor against peripheral nerve disease
Qi, T., Yang, Q., Qin, H., Zhu, Y., Chen, J., Zhou, H., Weng, J., Zeng, H., & Yu, F. (2025) · Brain‐X · doi:10.1002/brx2.70022 · Cited by 2
Self-assembling scaffolds epigenetically reactivate and electroactively guide neuronal regeneration to restore central neural circuits
Tong, S., Ye, S., Ma, F., Xie, X., Sun, Y., Ma, C., Shi, T., Cheng, Z., Li, C., Han, W., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-72397-6 · Cited by 2
Comparative analysis of Antigliotic Guiding Regenerative Gel (AGRG - LDP-916) for peripheral nerve reconstruction: Evidence from prospective randomized controlled studies
Rochkind, S., Goldlust, A., & Almog, M. (2026) · Brain and Spine · doi:10.1016/j.bas.2026.106115 · Cited by 2
Translational Challenges in Soft Tissue Regeneration
Liu, J., Ernst, J., Klingelhoefer, E., Saul, D., Lehmann, W., Felmerer, G., & Schilling, A. F. (2019) · Springer eBooks · doi:10.1007/978-3-030-19958-6_23 · Cited by 2
Preparation and Characterization of Conductive Chitosan/Polypyrrole Composites for Neural Repair
Shi, Y., Hu, Q. L., Wang, S., Zhu, X. H., Gong, C., Liao, X., & Liu, X. (2020) · IOP Conference Series Materials Science and Engineering · doi:10.1088/1757-899x/774/1/012113 · Cited by 2
Mathematical Modeling for Nerve Repair Research
Laranjeira, S., Coy, R., & Shipley, R. J. (2022) · Reference series in biomedical engineering · doi:10.1007/978-3-030-21052-6_10 · Cited by 2
Polymers and composites for peripheral nerve repair
Blekhman, M. G., James, A. J. B., Roberson, R., Adams, F., Zheng, Z., Llull, R., Katz, A. J., & Levi, N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99690-7.00004-2 · Cited by 2
Application of Adipose Stem Cells in 3D Nerve Guidance Conduit Prevents Muscle Atrophy and Improves Distal Muscle Compliance in a Peripheral Nerve Regeneration Model
Trâmbițaș, C., Cordoș, B. A., Dorobanțu, D. C., Vintilă, C., Ion, A. P., Pap, T., Camelia, D., Puiac, C., Arbănași, E. M., Ciucanu, C. C., et al. (2024) · Bioengineering · doi:10.3390/bioengineering11020184 · Cited by 2
PDMS-based flexible and conductive composite films containing modified PEDOT:PSS coated channels as a potential neural conduit
Buyukuysal, O. G., Kilic, B., Karaaslan, Ç., Gokcen, D., Bayram, C., & Aydin, H. M. (2025) · Materials Advances · doi:10.1039/d4ma01205d · Cited by 1
Application of Cellulose Scaffolds for Drug Delivery and MicroRNAs in Bone Formation and Bone Defect Repair
Rahdan, F., Ghahremani‐Nasab, M., Hadizadeh, M., Salahpour‐Anarjan, F., Rahdan, D., Dianat‐Moghadam, H., Shanehbandi, D., & Alizadeh, E. (2025) · Regenerative Engineering and Translational Medicine · doi:10.1007/s40883-025-00419-8 · Cited by 2
A laminin-mimicking hydrogel as regenerative microenvironment for the repair of peripheral nerve injury
Wen, Z., Song, L., Liu, P., Chin, A. T. Z.-E., Zhou, W., & Hu, Q. (2025) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2025.137369 · Cited by 2
Neural tissue microphysiological systems in the era of patient-derived pluripotent stem cells
Mungenast, A. E., Aron, R., White, J. D., Tardiff, D. F., & Raja, W. K. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813671-3.00009-8 · Cited by 2
Graphene on SiC
Convertino, D., Marchetti, L., & Coletti, C. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90609-8.00002-8 · Cited by 2
Effect of fetal cerebellar tissue transplantation on the restoration of hind limb locomotor function in rats with spinal cord injury
Medvediev, V. V., Senchyk, Y., Геннадиевна, Д. Н., Dychko, S., & Цымбалюк, В. И. (2016) · Cell and Organ Transplantology · doi:10.22494/cot.v4i2.57 · Cited by 2
6.17 Peripheral Nerve Regeneration ☆
Mokarram, N., Jain, A., Dymanus, K., Valmikinathan, C. M., & Bellamkonda, R. V. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803581-8.10145-6 · Cited by 2
Oral nerve tissue repair and regeneration
Jazayeri, H. E., Fahimipour, F., Tahriri, M., Almeida, L. E., & Tayebi, L. (2017) · Elsevier eBooks · doi:10.1016/b978-0-08-100961-1.00019-0 · Cited by 2
Applications of 3D Bioprinting ∗ ∗With minor contributions by Dr. Weijie Peng, The Pennsylvania State University.
Ozbolat, I. T. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803010-3.00009-3 · Cited by 2
3D bioprinting nerve
Hsu, S., & Chen, C.-W. (2018) · Elsevier eBooks · doi:10.1016/b978-0-08-101103-4.00016-8 · Cited by 2
Is Hypoesthesia in Mental and Incisive Nerves Areas A Complication of Inferior Alveolar Nerve Block or/and Wisdom Tooth Odontectomy?
Mirică, I. C. (2018) · Biomedical Journal of Scientific & Technical Research · doi:10.26717/bjstr.2018.08.001665 · Cited by 2
Screening of NogoA/NTR-Related Differential Genes in Rat Sciatic Nerve Injury Signal Pathway
Jiang, J., Zhang, Z., Yu, Y., Luan, M., Ma, Z., Gao, F., & Yu, S. (2019) · Personalized Medicine · doi:10.2217/pme-2018-0088 · Cited by 2
Nanofiber-based hydrogels and aerogels
Sun, L. X., & Wu, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-08-102850-6.00012-7 · Cited by 2
Translation and Applications of Biofabrication
Kim, J. H., Atala, A., & Yoo, J. J. (2018) · Springer eBooks · doi:10.1007/978-3-319-45444-3_17 · Cited by 2
Epothilone B loaded in acellular nerve allograft enhanced sciatic nerve regeneration in rats
Khudhur, Z. O., Abdulqadir, S. Z., Mzury, A. F. A., Rasoul, A. A., Smail, S. W., Ghayour, M. B., & Abdolmaleki, A. (2023) · Fundamental and Clinical Pharmacology · doi:10.1111/fcp.12961 · Cited by 2
Tissue Engineering for Sciatic Nerve Repair: Review of Methods and Challenges
Ebrahimi-kia, Y., Davoudi, P., & Bordbar, S. (2023) · Journal of Medical and Biological Engineering · doi:10.1007/s40846-023-00833-9 · Cited by 2
Smart Scaffold Constructs for Regenerative Medicine and Tissue Engineering
Choudhary, P., Gupta, A., Gupta, S. K., Dwivedi, S., & Singh, S. (2024) · doi:10.1002/9781394186488.ch3 · Cited by 2
PERCUTANEOUS LEFT ATRIAL APPENDAGE CLOSURE IN A PATIENT WITH ATRIAL FIBRILLATION AND OSLER-WEBER-RENDU DISEASE
Gancarczyk, U., Podolec, P. S., Przewłocki, T., Prochownik, P., & Komar, M. (2019) · Wiadomości Lekarskie · doi:10.36740/wlek201910137 · Cited by 1
Growth factor delivery for neural tissue engineering
Çiftçi, K. A., Ayan, S., Yüvrük, E., & Yılmazer, Y. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90554-1.00006-9 · Cited by 2
Trends and key contributors in peripheral nerve regeneration research: A bibliometric study
Abdelwahab, S. I., Farasani, A. M., Khired, Z. A., Assiri, A., Elhilu, A. H., & Hassan, W. (2025) · Chinese Journal of Plastic and Reconstructive Surgery · doi:10.1016/j.cjprs.2025.05.002 · Cited by 1
Analysis of the Regeneration Ability of Adipose-Derived Schwann Cells for Sciatic Nerve Defects
Chen, L., & Qi, Z. (2025) · Annals of Plastic Surgery · doi:10.1097/sap.0000000000004338 · Cited by 1
Preparation of a Polycaprolactone/Chitosan/Graphene Oxide Composite Film and Application in Blueberry Packaging
Mu, L., Luo, H., Sun, S., Dai, S., Hou, J., Zou, X., & Meng, T. (2025) · BioNanoScience · doi:10.1007/s12668-025-02051-w · Cited by 1
Hydrogel-filled tubular scaffolds for directional tissue regeneration combining shape-memory polyester blends with hyaluronic acid click-hydrogels
Hidalgo-Yerga, Á., Resina, L., Casanovas, J., Enshaei, H., Estrany, F., Iribarren, J. I., Pérez‐Madrigal, M. M., & Alemán, C. (2025) · RSC Applied Polymers · doi:10.1039/d5lp00098j · Cited by 2
Extracellular matrix-modified helix-flexible nerve conduit with optimal mechanics and nerve regenerating properties
Tan, Y., Yi, J., Shi, P., Wei, Q., Cui, Y., Guan, Y., Cheng, H., Su, T., Yao, Q., Liu, H., et al. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102501 · Cited by 1
Bioprinting of live platelet-loaded nerve conduit using energy-dissipative hydrogel
Zhang, J., Wu, W., Ren, Y., Dai, X., Ye, S., Zhao, W. M., Liu, H., He, L., Li, B., Zhang, L., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.11.021 · Cited by 1
Nerve Grafts in Breast Reconstruction: A Narrative Review
Shen, Y., Zhang, J., Liu, Y., & Cai, H. (2025) · The Breast Journal · doi:10.1155/tbj/1035158 · Cited by 1
3D-Printed PLGA Scaffolds: Current Progress and Prospects for Soft-Tissue Engineering
Onaiwu, G. E., Angwe, B. I., Aigbodion, A. I., Uzoekwe, N. M., Uwadiae, E. O., Okojie, M. E., Ugheighele, S. E., Oghenetega, S., & Ifijen, K. H. (2026) · The minerals, metals & materials series · doi:10.1007/978-3-032-13828-6_60 · Cited by 1
Bilayer nerve guidance conduits for continuous delivery of NGF@ZIF-8 nanoparticles for peripheral nerve injury repair
Zhang, X., Zhu, Q., Rong, H., Zhu, S., Feng, P., Li, J., Wang, Y., Cheng, H., Liu, W., Sun, J., et al. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04553-5 · Cited by 2
Piezoelectric-hydrogen synergy in electrospun oriented fibrous scaffold enables multimodal repair of long-distance peripheral nerve defect
Gu, H., Zhao, S., Gou, Y., Yuan, Y., Li, Y., Ren, H., Jin, Y., Li, B., Xuan, H., Xue, Y., et al. (2026) · Regenerative Biomaterials · doi:10.1093/rb/rbag156 · Cited by 1
PVDF/PPy nanofibrous membranes for peripheral nerve lesion treatments
Li, L., Cook, J. E., Cheng, Z. ‐., & Zhang, X. (2017) · IEEE International Symposium on Applications of Ferroelectrics (ISAF) · doi:10.1109/isaf.2017.8000209 · Cited by 1
Nanomaterial Design and Tests for Neural Tissue Engineering
Xue, J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815341-3.00008-0 · Cited by 1
Clinical Functions of Regenerative Dentistry and Tissue Engineering in Treatment of Oral and Maxillofacial Soft Tissues
Jamalpour, M. R., Vahdatinia, F., Vargas, J., & Tayebi, L. (2019) · Springer eBooks · doi:10.1007/978-3-030-21583-5_10 · Cited by 1
Ingeniería Tisular Para Regeneración Nerviosa: Una Revisión
Guardo-Gómez, V., Fajardo-Perdomo, M. A., Muñoz, A. L., & Gómez, L. A. (2020) · Revista chilena de neuro-psiquiatría · doi:10.4067/s0717-92272020000100050 · Cited by 1
Next Generation Neural Interface Electronics
Williams, I., Leene, L. B., & Constandinou, T. G. (2022) · River Publishers eBooks · doi:10.1201/9781003337522-7 · Cited by 1
Biotextile-based scaffolds in tissue engineering
Yuan, Q., Ma, C., & Ma, M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90479-7.00014-2 · Cited by 1
Artificial intelligence in multiscale scaffolds for cancer organoids testbed
Katti, D. R., Katti, K. S., Gaikwad, H. K., & Jaswandkar, S. V. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-18498-7.00005-3 · Cited by 1
A near-infrared-activated heterostructure endowed nerve scaffold with electrical stimulation and antibacterial performance
Ding, F., Liu, S., Peng, S., Zhou, H., Qian, H., Wang, Y., Li, W., Qi, F., & Shuai, C. (2023) · Materials Today Sustainability · doi:10.1016/j.mtsust.2023.100579 · Cited by 1
Self-citation
Novel application of CHUANG BI FU biologic protein sponge in promoting peripheral nerve injury repair by regulating vascular regeneration
Cai, Y., Liu, J., Han, R., Ma, Z., Yu, K., Wu, P., Li, X., Wang, Z., & Wang, J. (2025) · European journal of medical research · doi:10.1186/s40001-025-02552-0 · Cited by 1
Potentiality of Graphene-Based Materials for Neural Repair
Portolés, M. T., & Serrano, M. C. (2016) · Carbon nanostructures · doi:10.1007/978-3-319-45639-3_6 · Cited by 1
Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Rats
da Silva, I. B., Lós, D. B., de Andrade, R. F., Maciel, C. D. C. S., de Castro, C. M. M. B., Aguiar, J. L. D. A., & de Moraes, S. R. A. (2019) · International Journal of Morphology · doi:10.4067/s0717-95022019000100289 · Cited by 1
Projeto de uma Prótese Neuroprotetiva em Policaprolactona e estudo das suas propriedades mecânicas para aplicação nos Nervos Fibular e Tibial
Palma, R. T., Arruda, G. C., & Bock, E. (2017) · The Academic Society Journal · doi:10.32640/tasj.2017.3.104 · Cited by 1
[Construction of Chinese peripheral nerve society and progress in repair and reconstruction of peripheral nerve injury].
Gu, L. (2018) · Europe PMC (PubMed Central) · doi:10.7507/1002-1892.201807020 · Cited by 1
Repair and Regeneration After Important Visceral Injury
Cheng, B., Fu, X., Jiang, J., Yang, C., Li, H., Wang, S., Wang, Y., Huang, Y., Li, X., Yang, Z., et al. (2021) · Springer eBooks · doi:10.1007/978-981-16-1182-7_7 · Cited by 1
Appropriate Animal Models for Translational Nerve Research
Haastert‐Talini, K. (2022) · Reference series in biomedical engineering · doi:10.1007/978-3-030-21052-6_9 · Cited by 1
Disease‐Specific Stem Cell Models for Toxicological Screenings and Drug Development
Jung, M., Jung, J., Schiller, J., & Schroeder, I. S. (2016) · Wiley eBooks · doi:10.1002/9781119135449.ch7 · Cited by 1
Neuronal Regeneration
Bartolo, L. D., & Messina, A. (2015) · Springer eBooks · doi:10.1007/978-3-642-40872-4_410-1 · Cited by 1
3D Printing rGO/PCL/Mel Bionic Conduit for Peripheral Nerve RegenerationPreprint
Zhang, Q., Zhang, J., Liu, Z., Wang, J., Zhang, Y., Dong, J., Gao, J., Zhang, L., Tang, P., & Wang, J. (2023) · Research Square · doi:10.21203/rs.3.rs-2888185/v1 · Cited by 1
Perspectives of bioinspired materials in regenerative medicine
Filho, G. P. C., & Moreira, S. M. G. (2016) · Elsevier eBooks · doi:10.1016/b978-0-08-100741-9.00006-1
An Introduction to Scaffolds, Biomaterial Surfaces, and Stem Cells
Deng, J., & Gao, C. (2016) · Springer eBooks · doi:10.1007/978-981-10-2293-7_1
Current Topics in Regenerative Medicine for the Laryngeal Tissues
Kishimoto, Y. (2017) · Springer eBooks · doi:10.1007/978-981-10-3698-9_10
Effects of physical stimuli applied via substrate/scaffold on in-vitro culture of mesenchymal stem cells and neurons
Xu, Q. (2017) · doi:10.32657/10356/72662
Electrospinning Novel Aligned Polymer Fiber Structures for Use in Neural Tissue Engineering
Martin, R. A. (2017) · doi:10.37099/mtu.dc.etdr/521
Assessment of Tissue Constructs In Vivo in Regenerative Engineering
Subramanian, A., & Sethuraman, S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.64097-7
In�vitro predegeneration of peripheral nerve; the effect of predegeneration period on rat Schwann cell cultures
Tomko, P., Slovinská, L., & Vanick�, I. (2018) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2018.7021
Engineering Hyaluronic Acid Carbon Nanotube Nanofibers: A Peripheral Nerve Interface To Electrically Stimulate Regeneration
Steel, E. M. (2018) · Human Biology
Biopolymer-Nanotube Nerve Guidance Conduit Drug Delivery for Peripheral Nerve Regeneration
Manoukian, O. S. (2019) · OpenCommons at University of Connecticut (University of Connecticut)
Advanced Scaffold-Based Therapeutics for Peripheral Nerve Repair
Lackington, W. A. (2019) · doi:10.25419/rcsi.10802984
Combining tissue engineering and gene delivery to enhance peripheral nerve regeneration
Busuttil, F. (2019) · UCL Discovery (University College London)
[Effect of cells in the epimysium conduit on the regeneration of peripheral nerve].
Feng, W., Lu, H., Xu, Z., Chen, L., Yang, X., & Qi, Z. (2018) · Europe PMC (PubMed Central) · doi:10.7507/1002-1892.201712092
Development of decellularised allogeneic nerve grafts
Webster, G. E. (2019) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
Direct ink writing of graphene-based composites : from inks to flexible architectures for biomedical applications
Stachera, P. N. (2020) · Research Explorer (The University of Manchester)
Poly(trimethylene carbonate)-based composites for biomedical applications
Guo, Z. (2020) · doi:10.3990/1.9789036550741
Research on Kinases and Peripheral Nerve Injury Repair
张, 守. (2021) · Bioprocess · doi:10.12677/bp.2021.114012
The efficacy of wrapping the neurorrhaphy site utilizing dura substitute: A case series
Elkholy, A. R., Sallam, A. M., AlShamekh, A. S., Alomar, N., Alghabban, F. A., Alzahrani, B. S., Bafaqih, S. M., Alsubaie, F., AlQadasi, K. S., Alturki, A. Y., et al. (2021) · Surgical Neurology International · doi:10.25259/sni_586_2021
Functional Screening and Biosafety Identify of the Potential Application of Let-7a in Injured Peripheral Nerve RegenerationPreprint
Chen, Q., Liu, Q., Wang, P., Qian, T., Wang, X., Yi, S., & Li, S. (2021) · Research Square · doi:10.21203/rs.3.rs-1100490/v1
Novel Biocomposite Engineering and Bio-Applications
Chinga‐Carrasco, G. (2018) · MDPI eBooks · doi:10.3390/books978-3-03897-383-6
The effect of cerebrospinal fluid-derived exosomes on neural differentiation of adipose mesenchymal stem cells in alginate hydrogel scaffold
Cheravi, M., Baharara, J., Yaghmaei, P., & Roudbari, N. H. (2022) · Nova Biologica Reperta · doi:10.52547/nbr.8.4.265
Peer Review #2 of "How training loads in the preparation and competitive period affect the biochemical indicators of training stress in youth soccer players? (v0.1)"
(2022) · PeerJ · doi:10.7287/peerj.13367v0.1/reviews/2
Peer Review #3 of "How training loads in the preparation and competitive period affect the biochemical indicators of training stress in youth soccer players? (v0.1)"
(2022) · PeerJ · doi:10.7287/peerj.13367v0.1/reviews/3
Peer Review #4 of "How training loads in the preparation and competitive period affect the biochemical indicators of training stress in youth soccer players? (v0.1)"
(2022) · PeerJ · doi:10.7287/peerj.13367v0.1/reviews/4
Peer Review #2 of "How training loads in the preparation and competitive period affect the biochemical indicators of training stress in youth soccer players? (v0.2)"
(2022) · PeerJ · doi:10.7287/peerj.13367v0.2/reviews/2
Peer Review #1 of "How training loads in the preparation and competitive period affect the biochemical indicators of training stress in youth soccer players? (v0.1)"
(2022) · PeerJ · doi:10.7287/peerj.13367v0.1/reviews/1
Regenerative Medicine by Membrane Operations
Piscioneri, A. (2016) · Springer eBooks · doi:10.1007/978-3-662-44324-8_2145
Desarrollo de un composito para reparación y regeneración de nervio periférico
Osorio-Londoño, D. (2019) · doi:10.24275/uami.pk02c9813
Nanoscale and Macroscale Scaffolds with Controlled-Release Polymeric Systems for Dental Craniomaxillofacial Tissue Engineering.
Rahman, S. U., Nagrath, M., Ponnusamy, S., & Arany, P. R. (2021) · doi:10.32920/14637144.v1
Regenerative Medicine by Membrane Operations
Piscioneri, A. (2015) · Springer eBooks · doi:10.1007/978-3-642-40872-4_2145-1
Mathematical Modeling for Nerve Repair Research
Laranjeira, S., Coy, R., & Shipley, R. J. (2021) · Reference series in biomedical engineering · doi:10.1007/978-3-030-06217-0_10-1
Dual-Bionic Regenerative Microenvironment for Peripheral Nerve RepairingPreprint
Guan, Y., Ren, Z., Yang, B., Xu, W., Wen-jun, W., Zhang, T., Li, D., Li, X., Chen, S., He, S., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4200782
3D Printing for Orthopedics
Li, L., & Jiang, Q. Y. (2022) · doi:10.1002/9783527831371.ch9
Chitosan-alginate porous scaffold incorporated with hydroalcoholic Zingiber officinale Roscoe extract for neural tissue engineering
Kafraj, H. S., Alipour, M., Shiravi, A., Hojati, V., & Khaksarian, M. (2023) · Journal of Pharmacy & Pharmacognosy Research · doi:10.56499/jppres22.1505_11.2.229
Biofabrication techniques for neural tissue engineering
Khandaker, M., Progri, H., Kalay, O. C., Yılmaz, T. G., Yüce, C., & Karpat, F. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90554-1.00004-5
Microfluidic systems for neural tissue engineering
Cesur, S., Ulağ, S., & Gündüz, O. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90554-1.00013-6
Transcriptome analysis of Long non-coding RNAs altered in sciatic nerves of aging SD ratsPreprint
Wu, G., Kuang, R., Zhang, Y., Zhu, Z., Xu, S., Liu, X., Xu, Y., & Luo, Y. (2023) · Research Square · doi:10.21203/rs.3.rs-2893758/v1

Authors: Gu, X., Ding, F., & Williams, D. F.
Affiliations: Nantong University (CN)
Wake Forest University Health Sciences (US)
ORCID: Gu, Xiaosong
Ding, Fei
Williams, David F.
Venue: Biomaterials
Publisher: Elsevier BV
Published: 2014-08
Volume: 35
Issue: 24
Pages: 6143-6156
ISSN: 0142-9612 (ISSN-L)
DOI: 10.1016/j.biomaterials.2014.04.064
OpenAlex: W1985525878
Cited by: 630
References: 280
Citations by year: 2026: 23 · 2025: 44 · 2024: 42 · 2023: 57 · 2022: 72 · 2021: 57 · 2020: 70 · 2019: 73 · 2018: 73 · 2017: 46 · 2016: 40 · 2015: 24 · 2014: 9
FWCI: 4.52
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Biomaterials (publishedVersion)
PubMed (publishedVersion)
Funders: National Key Basic Research Program of China (2014CB542202)
Hi-Tech Research and Development Program of China (2012AA020502)
National Natural Science Foundation of China (81130080, 81171180)
Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
Keywords: peripheral nerve regeneration, tissue-engineered nerve grafts, neural scaffolds, biocompatibility, supporting cells, growth factor release, RNA interference, angiogenesis, electrical stimulation, inflammatory mediators, bioactive peptides, autologous nerve graft, functional recovery
MeSH terms: Animals, Biocompatible Materials, Humans, Nerve Regeneration, Peripheral Nerves, Tissue Engineering, RNA Interference, Tissue Scaffolds

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Neural tissue engineering options for peripheral nerve regeneration

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks