Depression and Inflammation: An Intricate Relationship

From inflammation to sickness and depression: when the immune system subjugates the brain

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Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis.

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Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior

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Depressive disorders and immunity: 20 years of progress and discovery

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Immune suppression and immune activation in depression

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The monocyte-T-lymphocyte hypothesis of major depression

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Cumulative Depression Episodes Predict Later C-Reactive Protein Levels: A Prospective Analysis

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Stress and immunomodulation: the role of depression and neuroendocrine function

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Letters to Milena

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The impact of stress on students in secondary school and higher education

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Sleep health: Reciprocal regulation of sleep and innate immunity

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Mindfulness mediates the physiological markers of stress: Systematic review and meta-analysis

Pascoe, M. C., Thompson, D. R., Jenkins, Z. M., & Ski, C. F. (2017) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.08.004 · Cited by 579 · see citing works

A systematic review of randomised control trials on the effects of yoga on stress measures and mood

Pascoe, M. C., & Bauer, I. E. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.07.013 · Cited by 366 · see citing works

Priming the Inflammatory Pump of the CNS after Traumatic Brain Injury

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Prebiotic administration normalizes lipopolysaccharide (LPS)-induced anxiety and cortical 5-HT2A receptor and IL1-β levels in male mice

Savignac, H. M., Couch, Y., Stratford, M., Bannerman, D. M., Tzortzis, G., Anthony, D. C., & Burnet, P. W. J. (2016) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2015.10.007 · Cited by 223 · see citing works

Maternal high fat diet consumption during the perinatal period programs offspring behavior

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Depression and anxiety in patients with hereditary angioedema

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Mental Health Impacts of the COVID-19 Pandemic on International University Students, Related Stressors, and Coping Strategies

Lai, A. Y.-K., Lee, L., Wang, M.-P., Feng, Y., Lai, T. T.-K., Ho, L.-M., Lam, V. S.-F., Ip, M. S.-M., & Lam, T.-H. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.584240 · Cited by 237 · see citing works

Inflammatory cytokines influence measures of white matter integrity in Bipolar Disorder

Benedetti, F., Poletti, S., Hoogenboezem, T. A., Mazza, E., Ambrée, O., de Wit, H., Wijkhuijs, A. J. M., Locatelli, C., Bollettini, I., Colombo, C., et al. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.05.047 · Cited by 151 · see citing works

Exercising the worry away: how inflammation, oxidative and nitrogen stress mediates the beneficial effect of physical activity on anxiety disorder symptoms and behaviours

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Clocking in: chronobiology in rheumatoid arthritis

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Novel neuroimmunologic therapeutics in depression: A clinical perspective on what we know so far

Roman, M., & Irwin, M. R. (2020) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2019.09.016 · Cited by 132 · see citing works

The Humanistic, Societal, and Pharmaco-economic Burden of Angioedema

Longhurst, H. J., & Bygum, A. (2016) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-016-8575-2 · Cited by 133 · see citing works

The Emerging Field of Nutritional Mental Health

Kaplan, B. J., Rucklidge, J. J., Romijn, A., & McLeod, K. (2015) · Clinical Psychological Science · doi:10.1177/2167702614555413 · Cited by 132 · see citing works

Toll-Like Receptor Signaling in Depression

Figueroa‐Hall, L. K., Paulus, M. P., & Savitz, J. B. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104843 · Cited by 121 · see citing works

Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice

Worthen, R. J., Zighelboim, S. S. G., Jaramillo, C., & Beurel, E. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01922-1 · Cited by 109 · see citing works

Perspectives in affective disorders: Clocks and sleep

Wirz‐Justice, A., & Benedetti, F. (2019) · European Journal of Neuroscience · doi:10.1111/ejn.14362 · Cited by 108 · see citing works

Affective immunology: where emotions and the immune response converge

D’Acquisto, F. (2017) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2017.19.1/fdacquisto · Cited by 108 · see citing works

Ds-HMGB1 and fr-HMGB induce depressive behavior through neuroinflammation in contrast to nonoxid-HMGB1

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Elevated specific peripheral cytokines found in major depressive disorder patients with childhood trauma exposure: A cytokine antibody array analysis

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Research Review: The role of cytokines in depression in adolescents: a systematic review

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The antidepressant effects of hesperidin on chronic unpredictable mild stress-induced mice

Fu, H., Liu, L., Tong, Y. A., Li, Y., Zhang, X., Gao, X., Yong, J., Zhao, J., Dong, X. Y., Wen, K., et al. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.03.035 · Cited by 92 · see citing works

Anti-Depressive-like Behaviors of APN KO Mice Involve Trkb/BDNF Signaling Related Neuroinflammatory Changes

Li, W., Ali, T., Zheng, C., He, K., Liu, Z., Shah, F. A., Li, N., Yu, Z.-J., & Li, S. (2022) · Molecular Psychiatry · doi:10.1038/s41380-021-01327-3 · Cited by 80 · see citing works

Increased GFAP concentrations in the cerebrospinal fluid of patients with unipolar depression

Michel, M., Fiebich, B. L., Kuzior, H., Meixensberger, S., Berger, B., Maier, S., Nickel, K., Runge, K., Denzel, D., Pankratz, B., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01423-6 · Cited by 79 · see citing works

Esketamine alleviates postoperative depression-like behavior through anti-inflammatory actions in mouse prefrontal cortex

Wang, T., Weng, H., Zhou, H., Yang, Z., Tian, Z., Xi, B., & Li, Y. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.03.072 · Cited by 80 · see citing works

Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression

Tang, M.-M., Lin, W.-J., Pan, Y.-Q., & Li, Y.-C. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00255 · Cited by 73 · see citing works

Brief Mindfulness Training Reduces Salivary IL-6 and TNF-α in Young Women with Depressive Symptomatology

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The effort-doors task: Examining the temporal dynamics of effort-based reward processing using ERPs

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Relative Hypo- and Hypercortisolism Are Both Associated with Depression and Lower Quality of Life in Bipolar Disorder: A Cross-Sectional Study

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Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice

Guo, J., Lin, P., Zhao, X., Zhang, J., Wei, X., Wang, Q., & Wang, C. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.01.008 · Cited by 67 · see citing works

Insomnia and inflammation: A two hit model of depression risk and prevention

Irwin, M. R., & Piber, D. (2018) · World Psychiatry · doi:10.1002/wps.20556 · Cited by 65 · see citing works

Brain-immune crosstalk in the treatment of major depressive disorder

Branchi, I., Poggini, S., Capuron, L., Benedetti, F., Poletti, S., Tamouza, R., Drexhage, H. A., Penninx, B. W. J. H., & Pariante, C. M. (2020) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2020.11.016 · Cited by 64 · see citing works

Effects of Shambhavi Mahamudra Kriya, a Multicomponent Breath-Based Yogic Practice (Pranayama), on Perceived Stress and General Well-Being

Peterson, C. T., Bauer, S. M., Chopra, D., Mills, P., & Maturi, R. (2017) · Journal of Evidence-Based Complementary & Alternative Medicine · doi:10.1177/2156587217730934 · Cited by 59 · see citing works

Psychobiological mechanisms underlying the mood benefits of meditation: A narrative review

Pascoe, M. C., de Manincor, M., Tseberja, J., Hallgren, M. Å., Baldwin, P. A., & Parker, A. G. (2021) · Comprehensive Psychoneuroendocrinology · doi:10.1016/j.cpnec.2021.100037 · Cited by 61 · see citing works

Psychobiological Mechanisms Underlying the Mental Health Benefits of Yoga-Based Interventions: a Narrative Review

Pascoe, M. C., de Manincor, M., Hallgren, M. Å., Baldwin, P. A., Tseberja, J., & Parker, A. G. (2021) · Mindfulness · doi:10.1007/s12671-021-01736-z · Cited by 57 · see citing works

The SIRT-1/Nrf2/HO-1 axis: Guardians of neuronal health in neurological disorders

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C-reactive protein and cold-pressor tolerance in the general population: the Tromsø Study

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Biomarkers Common for Inflammatory Periodontal Disease and Depression: A Systematic Review

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Long-term mental health outcomes after unintentional burns sustained during childhood: a retrospective cohort study

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Molecular insights into the therapeutic promise of targeting HMGB1 in depression

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Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-κB and Nrf2

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Chronic inflammation drives glioma growth: cellular and molecular factors responsible for an immunosuppressive microenvironment

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Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress-induced depressive rats

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Contributions of the adaptive immune system to mood regulation: Mechanisms and pathways of neuroimmune interactions

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Preliminary evidence of a blunted anti-inflammatory response to exhaustive exercise in fibromyalgia

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Natural products-based polypharmacological modulation of the peripheral immune system for the treatment of neuropsychiatric disorders

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Childhood trauma and increased peripheral cytokines in young adults with major depressive: Population-based study

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The relationship between anxiety and quality of life in children with hereditary angioedema

Kessel, A., Farkas, H., Kivity, S., Veszeli, N., Kőhalmi, K. V., & Engel‐Yeger, B. (2017) · Pediatric Allergy and Immunology · doi:10.1111/pai.12758 · Cited by 36 · see citing works

Inflammation, depression, and anxiety disorder: A population-based study examining the association between Interleukin-6 and the experiencing of depressive and anxiety symptoms

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Depression Relationship with Dietary Patterns and Dietary Inflammatory Index in Women: Result from Ravansar Cohort Study

Moludi, J., Moradinazar, M., Hamzeh, B., Najafi, F., & Pasdar, Y. (2020) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s255912 · Cited by 33 · see citing works

Personality predictors of dementia diagnosis and neuropathological burden: An individual participant data meta‐analysis

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The Spread of COVID-19 in Russia: Immediate Impact on Mental Health of University Students

Zinchenko, Y. P., Shaigerova, L. A., Almazova, O. V., Shilko, R. S., Vakhantseva, O. V., Dolgikh, A. G., Veraksa, А., & Минимансурович, К. А. (2021) · Psychological Studies · doi:10.1007/s12646-021-00610-1 · Cited by 33 · see citing works

Association of DNA Methylation of the NLRP3 Gene with Changes in Cortical Thickness in Major Depressive Disorder

Han, K., Choi, K. W., Kim, A., Kang, W., Kang, Y., Tae, W., Han, M.-R., & Ham, B. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105768 · Cited by 32 · see citing works

A Phenomenological Study on the Positive and Negative Experiences of Chinese International University Students From Hong Kong Studying in the U.K. and U.S. in the Early Stage of the COVID-19 Pandemic

Lai, A. Y. K., Sit, S. M.-M., Lam, S. K. K., Choi, A. C.-M., Yiu, D. Y.-S., Lai, T. T.-K., Ip, M. S.-M., & Lam, T.-H. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.738474 · Cited by 30 · see citing works

Biomarkers of ketamine’s antidepressant effect: An umbrella review

Meshkat, S., Ho, R. C., Cao, B., Teopiz, K. M., Rosenblat, J. D., Rhee, T. G., Di Vincenzo, J. D., Ceban, F., Jawad, M. Y., & McIntyre, R. S. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.12.021 · Cited by 29 · see citing works

Stress Detection via Multimodal Multitemporal-Scale Fusion: A Hybrid of Deep Learning and Handcrafted Feature Approach

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Cytokine gene variations associated with trait and state anxiety in oncology patients and their family caregivers

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iTRAQ-based proteomics suggests LRP6, NPY and NPY2R perturbation in the hippocampus involved in CSDS may induce resilience and susceptibility

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Exploring the impact of ketogenic diet on multiple sclerosis: obesity, anxiety, depression, and the glutamate system

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A population-based retrospective cohort study to assess the mental health of patients after a non-intentional burn compared with uninjured people

Duke, J. M., Randall, S. M., Boyd, J., Wood, F. M., Fear, M. W., & Rea, S. M. (2018) · Burns · doi:10.1016/j.burns.2018.05.007 · Cited by 23 · see citing works

Exploring the therapeutic potential of omega-3 fatty acids in depression

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Higher rates of allergies, autoimmune diseases and low-grade inflammation markers in treatment-resistant major depression

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HMGB1 in depression: An overview of microglial HMBG1 in the pathogenesis of depression

Huang, X., Wang, B., Yang, J., Lian, Y.-J., Yu, H., & Wang, Y.-X. (2023) · Brain, Behavior, & Immunity - Health · doi:10.1016/j.bbih.2023.100641 · Cited by 22 · see citing works

Anxiety, Stress and the Resilience of University Students during the First Wave of the COVID-19 Pandemic

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Psychopathological symptoms in dermatology: A basic approach toward psychocutaneous disorders

Rahman, S. M., Abduelmula, A., & Jafferany, M. (2022) · International Journal of Dermatology · doi:10.1111/ijd.16344 · Cited by 20 · see citing works

Impact of anxiety, stress and depression related to COVID‐19 pandemic on the course of hereditary angioedema with C1‐inhibitor deficiency

Karabacak, D. E., Demir, S., Yeğit, O. O., Can, A., Terzioğlu, K., Ünal, D., Olgaç, M., Coşkun, R., Çolakoğlu, B., Büyüköztürk, S., et al. (2021) · Allergy · doi:10.1111/all.14796 · Cited by 19 · see citing works

Curcumin plays a local anti‐inflammatory and antioxidant role via the HMGB1/TLR4/NF‐ΚB pathway in rat masseter muscle under psychological stress

Li, M., Huang, F., Sun, Y., Jiang, W., Chen, Y., & Zhang, M. (2021) · Journal of Oral Rehabilitation · doi:10.1111/joor.13289 · Cited by 18 · see citing works

The role of microglia in chronic pain and depression: innocent bystander or culprit?

Yin, N., Yan, E., Duan, W., Mao, C., Qin, F., Yang, C., Hu, Y., & Xu, X. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05780-4 · Cited by 18 · see citing works

Effort and Appetitive Responding in Depression: Examining Deficits in Motivational and Consummatory Stages of Reward Processing Using the Effort-Doors Task

Bowyer, C. B., Brush, C. J., Patrick, C. J., & Hajcak, G. (2022) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2022.08.002 · Cited by 17 · see citing works

Early Life Stress, Neuroinflammation, and Psychiatric Illness of Adulthood

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C1q deletion exacerbates stress-induced learned helplessness behavior and induces neuroinflammation in mice

Madeshiya, A. K., Whitehead, C., Tripathi, A., & Pillai, A. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01794-4 · Cited by 16 · see citing works

Biomarkers of stress resilience: A review

Paribello, P., Branchi, I., Viglione, A., Mancini, G. F., Morena, M., Campolongo, P., & Manchia, M. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104052 · Cited by 16 · see citing works

Model-free immune therapy: A control approach to acute inflammation

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Facemask Wearing Among Chinese International Students From Hong Kong Studying in United Kingdom Universities During COVID-19: A Mixed Method Study

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Foot pain severity is associated with the ratio of visceral to subcutaneous fat mass, fat-mass index and depression in women

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