The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Global Resting-State Functional Magnetic Resonance Imaging Analysis Identifies Frontal Cortex, Striatal, and Cerebellar Dysconnectivity in Obsessive-Compulsive Disorder
Open accessAbstract
Background Obsessive-compulsive disorder (OCD) is associated with regional hyperactivity in cortico-striatal circuits. However, the large-scale patterns of abnormal neural connectivity remain uncharacterized. Resting-state functional connectivity studies have shown altered connectivity within the implicated circuitry, but they have used seed-driven approaches wherein a circuit of interest is defined a priori. This limits their ability to identify network abnormalities beyond the prevailing framework. This limitation is particularly problematic within the prefrontal cortex (PFC), which is large and heterogeneous and where a priori specification of seeds is therefore difficult. A hypothesis-neutral, data-driven approach to the analysis of connectivity is vital.Methods We analyzed resting-state functional connectivity data collected at 3T in 27 OCD patients and 66 matched control subjects with a recently developed data-driven global brain connectivity (GBC) method, both within the PFC and across the whole brain.Results We found clusters of decreased connectivity in the left lateral PFC in both whole-brain and PFC-restricted analyses. Increased GBC was found in the right putamen and left cerebellar cortex. Within regions of interest in the basal ganglia and thalamus, we identified increased GBC in dorsal striatum and anterior thalamus, which was reduced in patients on medication. The ventral striatum/nucleus accumbens exhibited decreased global connectivity but increased connectivity specifically with the ventral anterior cingulate cortex in subjects with OCD.Conclusions These findings identify previously uncharacterized PFC and basal ganglia dysconnectivity in OCD and reveal differentially altered GBC in dorsal and ventral striatum. Results highlight complex disturbances in PFC networks, which could contribute to disrupted cortical-striatal-cerebellar circuits in OCD.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“recent fMRI studies of resting state connectivity have also generally supported a role for cortical-basal ganglia circuit dysfunction in OCD, demonstrating abnormal connectivity of orbitofrontal cortex 60–62, anterior cingulate 61,63, ventral striatum 61–63, dorsal striatum 62,63, putamen 60,63, and anterior thalamus 63.”
From DISSECTING OCD CIRCUITS: FROM ANIMAL MODELS TO TARGETED TREATMENTS: Review: Dissecting OCD Circuits: Animals to Treatments (2015) · cites this paper as [63]
In the citing paper
“other regions including subthalamic nucleus 60, cerebellum 63,64, and temporal cortex 64 have also been implicated, and directionality of findings varies across studies”
From DISSECTING OCD CIRCUITS: FROM ANIMAL MODELS TO TARGETED TREATMENTS: Review: Dissecting OCD Circuits: Animals to Treatments (2015) · cites this paper as [63]
In the citing paper
“These studies did not assess specific thalamic connections, whereas we showed greater connectivity between the thalamus and SMN using whole-brain network analysis, thereby refining our understanding of thalamic connectivity in OCD.”
From Functional disruption of cerebello-thalamo-cortical networks in obsessive-compulsive disorder (2020) · cites this paper as [34]
In the citing paper
“Finally, we used permutation testing(N=10,000) to test for differences in network strength between OCD and healthy participants(PBonferroni<0.05 for 9 comparisons), controlling for age, gender, and scanner(9,14,34).”
From Functional disruption of cerebello-thalamo-cortical networks in obsessive-compulsive disorder (2020) · cites this paper as [34]
In the citing paper
“Resting-state functional connectivity studies report greater global connectivity in the posterior cerebellum in OCD(34,35).”
From Functional disruption of cerebello-thalamo-cortical networks in obsessive-compulsive disorder (2020) · cites this paper as [34]
In the citing paper
“Others report elevated FPN-thalamic connectivity(17,77) and thalamic global connectivity in OCD(34).”
From Functional disruption of cerebello-thalamo-cortical networks in obsessive-compulsive disorder (2020) · cites this paper as [34]
In the citing paper
“On resting-state fMRI, reduced dorsal caudate-anterior thalamus functional connectivity was associated with symptomatic improvement following fluoxetine (Anticevic et al., 2014).”
From Cortico-striatal-thalamic loop circuits of the salience network: A central pathway in psychiatric disease and treatment (2016) · cites this paper as Anticevic et al., 2014
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
The assessment of anxiety states by rating
HAMILTON, M. (1959) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1959.tb00467.x · Cited by 11,455
Functional connectivity in the motor cortex of resting human brain using echo‐planar mri
Biswal, B., Zerrin Yetkin, F., Haughton, V. M., & Hyde, J. S. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910340409 · Cited by 9,812
The organization of the human cerebral cortex estimated by intrinsic functional connectivity
Thomas Yeo, B. T., Krienen, F. M., Sepulcre, J., Sabuncu, M. R., Lashkari, D., Hollinshead, M., Roffman, J. L., Smoller, J. W., Zöllei, L., Polimeni, J. R., et al. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00338.2011 · Cited by 9,182
Cohen, J. (1992) · Psychological Bulletin · doi:10.1037//0033-2909.112.1.155 · Cited by 8,771
Fischl, B., Salat, D. H., Busa, E., Albert, M., Dieterich, M., Haselgrove, C., van der Kouwe, A., Killiany, R., Kennedy, D., Klaveness, S., et al. (2002) · Neuron · doi:10.1016/s0896-6273(02)00569-x · Cited by 8,610
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Fox, M. D., Snyder, A. Z., Vincent, J. L., Corbetta, M., Van Essen, D. C., & Raichle, M. E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504136102 · Cited by 8,553
Parallel organization of functionally segregated circuits linking basal ganglia and cortex
Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.09.030186.002041 · Cited by 8,527
The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110048007 · Cited by 7,712
The organization of the human cerebellum estimated by intrinsic functional connectivity
Buckner, R. L., Krienen, F. M., Castellanos, A., Diaz, J. C., & Yeo, B. T. T. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00339.2011 · Cited by 7,304
Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging
Fox, M. D., & Raichle, M. E. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2201 · Cited by 6,700
The reward circuit: linking primate anatomy and human imaging
Haber, S. N., & Knutson, B. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.129 · Cited by 3,718
Inhibition and the right inferior frontal cortex
Aron, A. R., Robbins, T. W., & Poldrack, R. A. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.02.010 · Cited by 3,197
Toward discovery science of human brain function
Biswal, B. B., Mennes, M., Zuo, X.-N., Gohel, S., Kelly, C., Smith, S. M., Beckmann, C. F., Adelstein, J. S., Buckner, R. L., Colcombe, S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911855107 · Cited by 2,970
Kessler, R. C., Petukhova, M., Sampson, N. A., Zaslavsky, A. M., & Wittchen, H. (2012) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.1359 · Cited by 2,947 · cited 2×
“7% of the population at some point during their lives(3,4).”
Buckner, R. L., Sepulcre, J., Talukdar, T., Krienen, F. M., Liu, H., Hedden, T., Andrews-Hanna, J. R., Sperling, R. A., & Johnson, K. A. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.5062-08.2009 · Cited by 2,862
The Yale-Brown Obsessive Compulsive Scale: II. Validity
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110054008 · Cited by 2,799
The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication
Ruscio, A. M., Stein, D. J., Chiu, W. T., & Kessler, R. C. (2010) · Molecular Psychiatry · doi:10.1038/mp.2008.94 · Cited by 2,771
Alexander, G. E., Crutcher, M. D., & DeLong, M. R. (1990) · PubMed · Cited by 2,422
The Yale-Brown Obsessive-Compulsive Scale: measures of internal consistency.
Kim, S.-W., Dysken, M., Pheley, A., & Hoover, K. M. (1994) · Psychiatry Research · doi:10.1016/0165-1781(94)90039-6 · Cited by 2,333
(1991) · Progress in Brain Research · doi:10.1016/s0079-6123(08)62678-3 · Cited by 1,961
Habits, Rituals, and the Evaluative Brain
Graybiel, A. M. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112851 · Cited by 1,697
Baxter, L. R. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820090009002 · Cited by 1,293
Clinical applications of resting state functional connectivity
Fox, M. (2010) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2010.00019 · Cited by 1,219
Menzies, L., Chamberlain, S. R., Laird, A. R., Thelen, S. M., Sahakian, B. J., & Bullmore, E. T. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.09.005 · Cited by 1,190
Practice Guideline for the Treatment of Patients With Obsessive-Compulsive Disorder
(2008) · APA Practice Guidelines for the Treatment of Psychiatric Disorders: Comprehensive Guidelines and Guideline Watches · doi:10.1176/appi.books.9780890423363.149114 · Cited by 1,028
Abramowitz, J. S., Taylor, S., & McKay, D. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60240-3 · Cited by 1,002
Rauch, S. L. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950010062008 · Cited by 880
Voxel-wise meta-analysis of grey matter changes in obsessive-compulsive disorder
Radua, J., & Mataix-Cols, D. (2009) · British Journal of Psychiatry · doi:10.1192/bjp.bp.108.055046 · Cited by 863
Local Cerebral Glucose Metabolic Rates in Obsessive-Compulsive Disorder
Baxter, L. R. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800150017003 · Cited by 860
The cerebellum communicates with the basal ganglia
Hoshi, E., Tremblay, L., Féger, J., Carras, P. L., & Strick, P. L. (2005) · Nature Neuroscience · doi:10.1038/nn1544 · Cited by 848
The basal ganglia communicate with the cerebellum
Bostan, A. C., Dum, R. P., & Strick, P. L. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000496107 · Cited by 780
Denys, D., Mantione, M., Figee, M., van den Munckhof, P., Koerselman, F., Westenberg, H., Bosch, A., & Schuurman, R. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.122 · Cited by 763
The organization of the human striatum estimated by intrinsic functional connectivity
Choi, E. Y., Yeo, B. T. T., & Buckner, R. L. (2012) · Journal of Neurophysiology · doi:10.1152/jn.00270.2012 · Cited by 746
Meta-analysis of the symptom structure of obsessive–compulsive disorder
Bloch, M. H., Landeros-Weisenberger, A., Rosario, M. C., Pittenger, C., & Leckman, J. F. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.08020320 · Cited by 681
Self-citationCerebral glucose metabolism in childhood-onset obsessive-compulsive disorder
Swedo, S. E. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810060038007 · Cited by 671
Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder
Breiter, H. C. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830070041008 · Cited by 626
Global Connectivity of Prefrontal Cortex Predicts Cognitive Control and Intelligence
Cole, M. W., Yarkoni, T., Repovs, G., Anticevic, A., & Braver, T. S. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0536-12.2012 · Cited by 613
Self-citationGillan, C. M., Papmeyer, M., Morein-Zamir, S., Sahakian, B. J., Fineberg, N. A., Robbins, T. W., & de Wit, S. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.10071062 · Cited by 609 · cited 1×
“Damage to the left VLPFC has been associated with impairments in task switching, possibly reflecting a deficiency in top-down regulation of established procedures(69); a related deficiency might contribute to the perseverative behaviors seen in OCD and to difficulty in controlling habitual behavior(70).”
Identifying the brain's most globally connected regions
Cole, M. W., Pathak, S., & Schneider, W. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.11.001 · Cited by 572
Self-citationAltered corticostriatal functional connectivity in obsessive-compulsive disorder
Harrison, B. J., Soriano-Mas, C., Pujol, J., Ortiz, H., López-Solà, M., Hernández-Ribas, R., Deus, J., Alonso, P., Yücel, M., Pantelis, C., et al. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.152 · Cited by 571
Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder
(1988) · American Journal of Psychiatry · doi:10.1176/ajp.145.12.1560 · Cited by 541
Local Cerebral Glucose Metabolic Rates in Obsessive-Compulsive Disorder
Benkelfat, C. (1990) · Archives of General Psychiatry · doi:10.1001/archpsyc.1990.01810210048007 · Cited by 538
Bottom-Up and Top-Down Processes in Emotion Generation
Ochsner, K. N., Ray, R. D., Hughes, B., Kateri Mcrae, A., Cooper, J. C., Weber, J., Gabrieli, J. D. E., & Gross, J. J. (2009) · Psychological Science · doi:10.1111/j.1467-9280.2009.02459.x · Cited by 523
Resting state fMRI: A personal history
Biswal, B. B. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.01.090 · Cited by 522
A meta-analysis of functional neuroimaging in obsessive-compulsive disorder
Whiteside, S. P., Port, J. D., & Abramowitz, J. S. (2004) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2004.07.001 · Cited by 520
Basal Ganglia Disorders Associated with Imbalances in the Striatal Striosome and Matrix Compartments
Crittenden, J. R., & Graybiel, A. M. (2011) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2011.00059 · Cited by 470
Deep brain stimulation restores frontostriatal network activity in obsessive-compulsive disorder
Figee, M., Luigjes, J., Smolders, R., Valencia-Alfonso, C.-E., van Wingen, G., de Kwaasteniet, B., Mantione, M., Ooms, P., de Koning, P., Vulink, N., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3344 · Cited by 466
Cerebral Glucose Metabolism in Childhood-Onset Obsessive-Compulsive Disorder
Swedo, S. E. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820090018003 · Cited by 413
Radua, J., van den Heuvel, O. A., Surguladze, S., & Mataix-Cols, D. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.70 · Cited by 400 · cited 1×
“The right caudate and putamen have emerged as loci of pathology in many previous studies, using a variety of functional and structural imaging methods(11,13,15,73).”
Aron, A. R., Monsell, S., Sahakian, B. J., & Robbins, T. W. (2004) · Brain · doi:10.1093/brain/awh169 · Cited by 372
The neural bases of obsessive-compulsive disorder in children and adults
Maia, T. V., Cooney, R. E., & Peterson, B. S. (2008) · Development and Psychopathology · doi:10.1017/s0954579408000606 · Cited by 362 · cited 4×
“These studies have provided confirmatory evidence of dysconnectivity within the networks previously identified using baseline or provocationrelated perfusion measures(11,15,35).”
InfluentialGoodman, W. K., Foote, K. D., Greenberg, B. D., Ricciuti, N., Bauer, R., Ward, H., Shapira, N. A., Wu, S. S., Hill, C. L., Rasmussen, S. A., et al. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.11.028 · Cited by 362
Dysfunctional reward circuitry in obsessive-compulsive disorder
Figee, M., Vink, M., de Geus, F., Vulink, N., Veltman, D. J., Westenberg, H., & Denys, D. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.12.003 · Cited by 315
Adler, C. M., McDonough-Ryan, P., Sax, K. W., Holland, S. K., Arndt, S., & Strakowski, S. M. (2000) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(00)00022-4 · Cited by 313
Meta-analysis of brain volume changes in obsessive-compulsive disorder
Rotge, J.-Y., Guehl, D., Dilharreguy, B., Tignol, J., Bioulac, B., Allard, M., Burbaud, P., & Aouizerate, B. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.06.019 · Cited by 284
Mantovani, A., Simpson, H. B., Fallon, B. A., Rossi, S., & Lisanby, S. H. (2010) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145709990435 · Cited by 281
Abnormally high degree connectivity of the orbitofrontal cortex in obsessive-compulsive disorder
Beucke, J. C., Sepulcre, J., Talukdar, T., Linnman, C., Zschenderlein, K., Endrass, T., Kaufmann, C., & Kathmann, N. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.173 · Cited by 280
Global Prefrontal and Fronto-Amygdala Dysconnectivity in Bipolar I Disorder with Psychosis History
Anticevic, A., Brumbaugh, M. S., Winkler, A. M., Lombardo, L. E., Barrett, J., Corlett, P. R., Kober, H., Gruber, J., Repovs, G., Cole, M. W., et al. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.07.031 · Cited by 263
Self-citationJenike, M. A. (2004) · New England Journal of Medicine · doi:10.1056/nejmcp031002 · Cited by 260
Rotge, J.-Y., Guehl, D., Dilharreguy, B., Cuny, E., Tignol, J., Bioulac, B., Allard, M., Burbaud, P., & Aouizerate, B. (2008) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0838 · Cited by 254
Brain-behavior relationships in obsessive-compulsive disorder
Saxena, S., Bota, R. G., & Brody, A. L. (2001) · Seminars in Clinical Neuropsychiatry · doi:10.1053/scnp.2001.21833 · Cited by 247
Stern, E. R., Fitzgerald, K. D., Welsh, R. C., Abelson, J. L., & Taylor, S. F. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036356 · Cited by 245
Variable Global Dysconnectivity and Individual Differences in Schizophrenia
Cole, M. W., Anticevic, A., Repovš, G., & Barch, D. M. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.02.010 · Cited by 235
Self-citationHarrison, B. J., Pujol, J., Cardoner, N., Deus, J., Alonso, P., López-Solà, M., Contreras-Rodríguez, O., Real, E., Segalàs, C., Blanco-Hinojo, L., et al. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.10.006 · Cited by 234
Rotge, J.-Y., Langbour, N., Guehl, D., Bioulac, B., Jaafari, N., Allard, M., Aouizerate, B., & Burbaud, P. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.175 · Cited by 228
Driesen, N. R., McCarthy, G., Bhagwagar, Z., Bloch, M., Calhoun, V, D'Souza, D. C., Gueorguieva, R., He, G., Ramachandran, R., Suckow, R. F., et al. (2013) · Molecular Psychiatry · doi:10.1038/mp.2012.194 · Cited by 224
Self-citationCorticostriatal Interactions during Learning, Memory Processing, and Decision Making
Pennartz, C. M. A., Berke, J. D., Graybiel, A. M., Ito, R., Lansink, C. S., van der Meer, M., Redish, A. D., Smith, K. S., & Voorn, P. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3177-09.2009 · Cited by 213
Saxena, S., Brody, A. L., Ho, M. L., Alborzian, S., Maidment, K. M., Zohrabi, N., Ho, M. K., Huang, S., Wu, H.-M., & Baxter, L. R. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.3.250 · Cited by 201
Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: a SPECT study
Machlin, S. R., Harris, G. J., Pearlson, G. D., Hoehn‐Saric, R., Jeffery, P., & Camargo, E. E. (1991) · American Journal of Psychiatry · doi:10.1176/ajp.148.9.1240 · Cited by 189
The evolutionary origin of the vertebrate basal ganglia and its role in action selection
Grillner, S., Robertson, B., & Stephenson‐Jones, M. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2012.246660 · Cited by 184
Corticostriatal functional connectivity in non-medicated patients with obsessive-compulsive disorder
Sakai, Y., Narumoto, J., Nishida, S., Nakamae, T., Yamada, K., Nishimura, T., & Fukui, K. (2011) · European Psychiatry · doi:10.1016/j.eurpsy.2010.09.005 · Cited by 173
Developmental alterations of frontal-striatal-thalamic connectivity in obsessive-compulsive disorder
Fitzgerald, K. D., Welsh, R. C., Stern, E. R., Angstadt, M., Hanna, G. L., Abelson, J. L., & Taylor, S. F. (2011) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2011.06.011 · Cited by 165
Martuzzi, R., Ramani, R., Qiu, M., Shen, X., Papademetris, X., & Constable, R. T. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.06.075 · Cited by 163
Fitzgerald, K. D., Stern, E. R., Angstadt, M., Nicholson-Muth, K. C., Maynor, M. R., Welsh, R. C., Hanna, G. L., & Taylor, S. F. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.08.018 · Cited by 152
Abnormal small-world architecture of top-down control networks in obsessive-compulsive disorder
Zhang, T. (2011) · Journal of Psychiatry & Neuroscience · doi:10.1503/jpn.100006 · Cited by 134
Jang, J. H., Kim, J., Jung, W. H., Choi, J., Jung, M. H., Lee, J., Choi, C., Kang, D., & Kwon, J. S. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.03.031 · Cited by 120
Cerebellar morphology in Tourette syndrome and obsessive‐compulsive disorder
Tobe, R. H., Bansal, R., Xu, D., Hao, X., Liu, J., Sanchez, J., & Peterson, B. S. (2010) · Annals of Neurology · doi:10.1002/ana.21918 · Cited by 110
Hypofunctioning of sensory gating mechanisms in patients with obsessive-compulsive disorder
Rossi, S., Bartalini, S., Ulivelli, M., Mantovani, A., Di Muro, A., Goracci, A., Castrogiovanni, P., Battistini, N., & Passero, S. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.09.023 · Cited by 105
Kang, D.-H., Jang, J. H., Han, J. Y., Kim, J.-H., Jung, W. H., Choi, J.-S., Choi, C.-H., & Kwon, J. S. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.11.001 · Cited by 105
Riluzole Augmentation in Treatment-Refractory Obsessive-Compulsive Disorder
Pittenger, C., Kelmendi, B., Wasylink, S., Bloch, M. H., & Coric, V. (2008) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e3181727548 · Cited by 83
Self-citationRotge, J.-Y., Langbour, N., Jaafari, N., Guehl, D., Bioulac, B., Aouizerate, B., Allard, M., & Burbaud, P. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.10.007 · Cited by 70
Anticevic, A., Repovš, G., Krystal, J. H., & Barch, D. M. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.07.007 · Cited by 69
Self-citationLi, P., Li, S., Dong, Z.-Y., Luo, J., Han, H., Xiong, H., Guo, Z., & Li, Z. (2012) · Neuroreport · doi:10.1097/wnr.0b013e328355a5fe · Cited by 30
Cited by
Sorted by citations
The basal ganglia and the cerebellum: nodes in an integrated network
Bostan, A. C., & Strick, P. L. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0002-7 · Cited by 786
Peters, S. K., Dunlop, K., & Downar, J. (2016) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2016.00104 · Cited by 611
“On resting-state fMRI, reduced dorsal caudate-anterior thalamus functional connectivity was associated with symptomatic improvement following fluoxetine (Anticevic et al., 2014).”
BackgroundObsessive-compulsive disorder: Puzzles and prospects
Robbins, T. W., Vaghi, M. M., & Banca, P. (2019) · Neuron · doi:10.1016/j.neuron.2019.01.046 · Cited by 510
The Frontoparietal Control System: A Central Role in Mental Health
Cole, M. W., Repovš, G., & Anticevic, A. (2014) · The Neuroscientist · doi:10.1177/1073858414525995 · Cited by 461
Self-citationDelay Discounting as a Transdiagnostic Process in Psychiatric Disorders
Amlung, M. T., Marsden, E., Holshausen, K., Morris, V. L., Patel, H., Vedelago, L., Naish, K. R., Reed, D. D., & McCabe, R. E. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2019.2102 · Cited by 396
Metadata
- Authors
- Anticevic, A., Hu, S., Zhang, S., Savic, A., Billingslea, E., Wasylink, S., Repovs, G., Cole, M. W., Bednarski, S., Krystal, J. H., Bloch, M. H., Li, C.-S. R., & Pittenger, C.
- Affiliations
- Yale University (US)
- Washington University in St. Louis (US)
- Corresponding author
- Pittenger, Christopher
- ORCID
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2014-04
- Volume
- 75
- Issue
- 8
- Pages
- 595-605
- ISSN
- 0006-3223 (ISSN-L)
- PMC
- PMC3969771
- OpenAlex
- W2009341243
- Cited by
- 268
- References
- 84
- Citations by year
- 2026: 11 · 2025: 15 · 2024: 19 · 2023: 14 · 2022: 28 · 2021: 19 · 2020: 27 · 2019: 23 · 2018: 25 · 2017: 19 · 2016: 29 · 2015: 20 · 2014: 17
- FWCI
- 24.85
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- The Yale Center for Clinical Investigation (UL1RR024139)
- The Fullbright Foundation (K99MH0968010 (MWC), K08MH081190 (CP), R01MH095790 (CP))
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Keywords
- obsessive-compulsive disorder, resting-state functional connectivity, global brain connectivity, basal ganglia, dorsal striatum, ventral striatum, nucleus accumbens, cerebellum, anterior thalamic nuclei, antipsychotic effects, ventral anterior cingulate cortex
- MeSH terms
- Adolescent, Adult, Aged, Brain, Brain Mapping, Cerebellum, Corpus Striatum, Female, Frontal Lobe, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neural Pathways, Obsessive-Compulsive Disorder, Rest, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
