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Personality-dependent effects of oxytocin: Greater social benefits for high alexithymia scorers
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Originally known for its role in labor and lactation, oxytocin (OT) has recently been shown to facilitate social behaviour by improving socio-emotional abilities. However, whether OT is equally beneficial to all people, or whether is it particularly beneficial to less emotionally/socially competent (i.e., high alexithymia) individuals it is not yet known. We investigated the effects of OT on individuals of varying socio-emotional ability by randomly assigning sixty male students to receive either oxytocin (OT) or a placebo (PL), and had them perform the Reading the Mind in the Eyes test (RMET). Results showed that whereas the performance of lower alexithymia individuals was equally good in both OT and PL conditions, the performance of higher alexithymia people was better under OT than PL. These results suggest that the effects of OT are not only context-dependent-as recently shown-but also personality dependent. They also provide new insights into the remediation of socio-emotional deficits.
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“It appears that the enhanced prosocial effects of intranasally administered OT are especially pronounced for individuals suffering from socio-emotional deficits, as is the case for individuals with Asperger syndrome (Andari et al., 2010) or high alexithymia (Luminet et al., 2011).”
From The effect of oxytocin on cooperation in a prisoner's dilemma depends on the social context and a person's social value orientation (2014) · cites this paper as Luminet et al., 2011
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Metadata
- Authors
- Luminet, O., Grynberg, D., Ruzette, N., & Mikolajczak, M.
- Affiliations
- Fund for Scientific Research (BE)
- UCLouvain (BE)
- Corresponding author
- Luminet, Olivier
- Venue
- Biological Psychology
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 87
- Issue
- 3
- Pages
- 401-406
- ISSN
- 0301-0511 (ISSN-L)
- OpenAlex
- W2024067798
- Cited by
- 107
- References
- 70
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 2 · 2023: 6 · 2022: 3 · 2021: 10 · 2020: 5 · 2019: 4 · 2018: 7 · 2017: 11 · 2016: 11 · 2015: 13 · 2014: 9 · 2013: 14 · 2012: 5
- FWCI
- 12.62
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Biological Psychology (publishedVersion)
- PubMed (publishedVersion)
- Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) (submittedVersion, other-oa)
- Funders
- Fonds De La Recherche Scientifique - FNRS
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- oxytocin, alexithymia, personality differences, social cognition, theory of mind, Reading the Mind in the Eyes Test, placebo, individual differences, social behavior
- MeSH terms
- Affective Symptoms, Emotions, Facial Expression, Humans, Male, Oxytocin, Personality, Social Behavior, Social Perception, Recognition, Psychology, Young Adult
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