Cited by 151Fibromyalgia and Chronic Fatigue Syndrome ResearchLong-Term Effects of COVID-19Traumatic Brain Injury Research

Is a full recovery possible after cognitive behavioural therapy for chronic fatigue syndrome?

Knoop, Hans, Bleijenberg, Gijs, Gielissen, Marieke F.M., van der Meer, Jos W.M., White, Peter D.·2007·Psychotherapy and Psychosomatics

Abstract

BACKGROUND: Cognitive behavioural therapy (CBT) for chronic fatigue syndrome (CFS) leads to a decrease in symptoms and disabilities. There is controversy about the nature of the change following treatment; some suggest that patients improve by learning to adapt to a chronic condition, others think that recovery is possible. The objective of this study was to find out whether recovery from CFS is possible after CBT. METHODS: The outcome of a cohort of 96 patients treated for CFS with CBT was studied. The definition of recovery was based on the absence of the criteria for CFS set up by the Center for Disease Control (CDC), but also took into account the perception of the patients' fatigue and their own health. Data from healthy population norms were used in calculating conservative thresholds for recovery. RESULTS: After treatment, 69% of the patients no longer met the CDC criteria for CFS. The percentage of recovered patients depended on the criteria used for recovery. Using the most comprehensive definition of recovery, 23% of the patients fully recovered. Fewer patients with a co-morbid medical condition recovered. CONCLUSION: Significant improvement following CBT is probable and a full recovery is possible. Sharing this information with patients can raise the expectations of the treatment, which may enhance outcomes without raising false hopes.

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Crossref · 10.1159/000099844

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Authors
Knoop, H., Bleijenberg, G., Gielissen, M. F. M., van der Meer, J. W. M., & White, P. D.
Affiliations
  • Radboud University Medical Center (NL)
  • Queen Mary University of London (GB)
Venue
Psychotherapy and Psychosomatics
Publisher
S. Karger AG
Published
2007
Volume
76
Issue
3
Pages
171-176
ISSN
  • 0033-3190 (ISSN-L)
  • 1423-0348
OpenAlex
W2172279241
Cited by
151
References
25
Citations by year
2026: 3 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 2 · 2020: 8 · 2019: 8 · 2018: 8 · 2017: 16 · 2016: 10 · 2015: 11 · 2014: 9 · 2013: 8 · 2012: 5
FWCI
6.63
Type
journal article
Language
en
Open access
closed
Locations
  • Psychotherapy and Psychosomatics (publishedVersion)
  • PubMed (publishedVersion)
  • Radboud Repository (Radboud University) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
  • Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
  • Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
Keywords
chronic fatigue syndrome, cognitive behavioral therapy, recovery, treatment outcomes, CDC diagnostic criteria, comorbidities, treatment expectations
MeSH terms
Adaptation, Psychological, Adult, Disability Evaluation, Female, Follow-Up Studies, Humans, Male, Middle Aged, Sick Role, Social Adjustment, Cohort Studies, Fatigue Syndrome, Chronic, Comorbidity, Cognitive Behavioral Therapy, Outcome Assessment, Health Care

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