Cancer related inflammation: The macrophage connection

Inflammation and cancer

Coussens, L. M., & Werb, Z. (2002) · Nature · doi:10.1038/nature01322 · Cited by 15,111

Inflammation and cancer: back to Virchow?

Balkwill, F., & Mantovani, A. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04046-0 · Cited by 7,746

Angiogenesis in cancer, vascular, rheumatoid and other disease

Folkman, J. (1995) · Nature Medicine · doi:10.1038/nm0195-27 · Cited by 7,627

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

Hanahan, D., & Folkman, J. (1996) · Cell · doi:10.1016/s0092-8674(00)80108-7 · Cited by 6,885

Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

Galon, J., Costes, A., Sanchez-Cabo, F., Kirilovsky, A., Mlecnik, B., Lagorce-Pagès, C., Tosolini, M., Camus, M., Berger, A., Wind, P., et al. (2006) · Science · doi:10.1126/science.1129139 · Cited by 6,516

A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer

Paik, S., Shak, S., Tang, G., Kim, C., Baker, J. B., Cronin, M. T., Baehner, F. L., Walker, M. G., Watson, D., Park, T., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa041588 · Cited by 6,321

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

MANTOVANI, A., SOZZANI, S., LOCATI, M., ALLAVENA, P., & SICA, A. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)02302-5 · Cited by 5,528

Involvement of chemokine receptors in breast cancer metastasis

Müller, A., Homey, B., Soto, H., Ge, N., Catron, D., Buchanan, M. E., McClanahan, T., Murphy, E., Yuan, W., Wagner, S. N., et al. (2001) · Nature · doi:10.1038/35065016 · Cited by 5,340

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Maxwell, P. H., Wiesener, M. S., Chang, G.-W., Clifford, S. C., Vaux, E. C., Cockman, M. E., Wykoff, C. C., Pugh, C. W., Maher, E. R., & Ratcliffe, P. J. (1999) · Nature · doi:10.1038/20459 · Cited by 5,180

Van Damme A.

Haine, M. M.-L., & Meeùs, N. (1986) · Cited by 3,464

Multifunctional nanoparticles for targeting cancer and inflammatory diseases

Jain, S., Doshi, A. S., Iyer, A. K., & Amiji, M. M. (2013) · Journal of drug targeting · doi:10.3109/1061186x.2013.832769 · Cited by 27

Immunomodulatory activity and molecular mechanisms of action of peptides derived from casein hydrolysate by alcalase and flavourzyme based on virtual screening

Jiang, Y., Li, S., Jiang, L., Mu, G., & Jiang, S. (2024) · Journal of Dairy Science · doi:10.3168/jds.2024-25224 · Cited by 25

A Hierarchical Metal–Organic Framework Intensifying ROS Catalytic Activity and Bacterial Entrapment for Engineering Self‐Antimicrobial Mask

Huang, W., Yuan, H., Yang, H., Shen, Y., Guo, L., Zhong, N., Wu, T. S., Shen, Y., Chen, G., Huang, S., et al. (2024) · Advanced Science · doi:10.1002/advs.202410703 · Cited by 26

PGE2 Released by Pancreatic Cancer Cells Undergoing ER Stress Transfers the Stress to DCs Impairing Their Immune Function

Montani, M. S. G., Benedetti, R., Piconese, S., Pulcinelli, F. M., Timperio, A. M., Romeo, M. A., Masuelli, L., Mattei, M., Bei, R., D’Orazi, G., et al. (2021) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-20-0699 · Cited by 28

Cancer Immunoediting: Elimination, Equilibrium, and Immune Escape in Solid Tumors

Wilczyński, J. R., & Nowak, M. (2022) · Experientia supplementum · doi:10.1007/978-3-030-91311-3_1 · Cited by 27

A positive feedback loop driven by fibronectin and IL-1β sustains the inflammatory microenvironment in breast cancer

Tunalı, G., Yanık, H., Öztürk, S. C., Canlı, S. D., Efthymiou, G., Yılmaz, K. B., Obberghen‐Schilling, E. V., & Esendağlı, G. (2023) · Breast Cancer Research · doi:10.1186/s13058-023-01629-0 · Cited by 27

Cross-talk between NO and HMGB1 in lymphocytic thyroiditis and papillary thyroid cancer

Mardente, S. (2010) · Oncology Reports · doi:10.3892/or_00001005 · Cited by 26

Alternatively Activated Macrophages Play an Important Role in Vascular Remodeling and Hemorrhaging in Patients with Brain Arteriovenous Malformation

Nakamura, Y., Sugita, Y., Nakashima, S., Okada, Y., Yoshitomi, M., Kimura, Y., Miyoshi, H., Morioka, M., & Ohshima, K. (2015) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2015.11.034 · Cited by 24

Tumor Immune Microenvironment in Gynecologic Cancers

Margul, D. J., Yu, C., & AlHilli, M. M. (2023) · Cancers · doi:10.3390/cancers15153849 · Cited by 24

Structural Characterization and Immunomodulatory Activity of a Novel Polysaccharide From Lycopi Herba

Zhang, W., Hu, Y., He, J., Guo, D., Zhao, J., & Li, P. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.691995 · Cited by 25

Daedalea gibbosa substances inhibit LPS-induced expression of iNOS by suppression of NF-κB and MAPK activities in RAW 264.7 macrophage cells

Mahajna, J. A. (2010) · International Journal of Molecular Medicine · doi:10.3892/ijmm_00000361 · Cited by 25

Visualization of the Biological Behavior of Tumor-Associated Macrophages in Living Mice with Colon Cancer Using Multimodal Optical Reporter Gene Imaging

Choi, Y. J., Oh, S.-G., Singh, T. D., Ha, J., Kim, D. W., Lee, S. W., Jeong, S. Y., Ahn, B., Lee, J., & Jeon, Y. H. (2016) · Neoplasia · doi:10.1016/j.neo.2016.01.004 · Cited by 25

Role of cytokines in combinatorial immunotherapeutics of non‐small cell lung cancer through systems perspective

Misra, P., & Singh, S. (2019) · Cancer Medicine · doi:10.1002/cam4.2112 · Cited by 25

MiR‐146b Mediates Endotoxin Tolerance in Human Phagocytes

Renzi, T. A., Rubino, M., Gornati, L., Garlanda, C., Locati, M., & Curtale, G. (2015) · Mediators of Inflammation · doi:10.1155/2015/145305 · Cited by 25

C5aR deficiency attenuates the breast cancer development via the p38/p21 axis

Chen, J., Sun, Z.-H., Chen, L., Xu, F., Zhao, Y., Li, G.-Q., Tang, M., Li, Y., Zheng, Q., Wang, S., et al. (2020) · Aging · doi:10.18632/aging.103468 · Cited by 24

Blocking the Notch signal transduction pathway promotes tumor growth in osteosarcoma by affecting polarization of TAM to M2 phenotype

Ren, S., Zhang, X., Hu, Y., Wu, J., Ju, Y., Sun, X., Liu, Y., & Shan, B. (2020) · Annals of Translational Medicine · doi:10.21037/atm-20-3881 · Cited by 24

Lessons from Cancer Immunoediting in Cutaneous Melanoma

Aris, M., Barrio, M. M., & Mordoh, J. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/192719 · Cited by 25

Exploiting the tumor microenvironment for theranostic imaging

Stasinopoulos, I. A., Penet, M., Chen, Z., Kakkad, S. M., Glunde, K., & Bhujwalla, Z. M. (2011) · NMR in Biomedicine · doi:10.1002/nbm.1664 · Cited by 24

A Review on the Phytochemical and Pharmacological Properties of Rosa laevigata: A Medicinal and Edible Plant

Li, B., Yuan, J., & Wu, J. (2021) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.c20-00743 · Cited by 23

Breast Tumor Angiogenesis and Tumor-Associated Macrophages: Histopathologist's Perspective

Ch’ng, E. S., Jaafar, H., & Sharif, S. E. T. (2011) · Pathology Research International · doi:10.4061/2011/572706 · Cited by 23

Serum galectin-1 in patients with multiple myeloma: associations with survival, angiogenesis, and biomarkers of macrophage activation

Andersen, M. N., Ludvigsen, M., Abildgaard, N., Petruskevicius, I., Hjortebjerg, R., Bjerre, M., Honoré, B., Møller, H. J., & Andersen, N. F. (2017) · OncoTargets and Therapy · doi:10.2147/ott.s124321 · Cited by 22

Co-culturing polarized M2 Thp-1-derived macrophages enhance stemness of lung adenocarcinoma A549 cells

Zhang, X., Zhu, M., Hong, Z., & Chen, C. (2021) · Annals of Translational Medicine · doi:10.21037/atm-21-1256 · Cited by 23

The prognostic impact of preoperative blood monocyte count in pathological T3N0M0 rectal cancer without neoadjuvant chemoradiotherapy

Zhang, L.-N., Xiao, W., OuYang, P., You, K., Zeng, Z., Ding, P.-R., Pan, Z.-Z., Xu, R., & Gao, Y.-H. (2015) · Tumor Biology · doi:10.1007/s13277-015-3560-6 · Cited by 23

Prognostic value of CD163+ macrophages in solid tumor malignancies: A scoping review

Mathiesen, H., Juul‐Madsen, K., Tramm, T., Vorup‐Jensen, T., Møller, H. J., Etzerodt, A., & Andersen, M. N. (2025) · Immunology Letters · doi:10.1016/j.imlet.2025.106970 · Cited by 23

Hormone replacement therapy is associated with reduced hepatocellular carcinoma risk and improved survival in postmenopausal women with hepatitis B: A nationwide long-term population-based cohort study

Wang, C., Lin, R., Hsu, H., & Tseng, Y. (2022) · PLoS ONE · doi:10.1371/journal.pone.0271790 · Cited by 22

M2 Macrophage-Derived Exosomes Regulate Myocardial Ischemia-Reperfusion And Pyroptosis Via ROS/NLRP3 Pathway

Hu, H., Qi, L., Ren, C., & Yan, S. (2022) · The Heart Surgery Forum · doi:10.1532/hsf.4919 · Cited by 22

Self-Renewal of Macrophages: Tumor-Released Factors and Signaling Pathways

Filiberti, S., Russo, M., Lonardi, S., Bugatti, M., Vermi, W., Tournier, C., & Giurisato, E. (2022) · Biomedicines · doi:10.3390/biomedicines10112709 · Cited by 25

Macrophages — Masters of Immune Activation, Suppression and Deviation

Foey, A. (2014) · InTech eBooks · doi:10.5772/57541 · Cited by 24

CEA in activated macrophages. New diagnostic possibilities for tumor markers in early colorectal cancer.

Japink, D., Leers, M. P. G., Sosef, M. N., & Nap, M. (2009) · PubMed · Cited by 22

CD40 signaling instructs chronic lymphocytic leukemia cells to attract monocytes via the CCR2 axis

van Attekum, M. H. A., van Bruggen, J. A. C., Slinger, E., Lebre, M. C., Reinen, E., Kersting, S., Eldering, E., & Kater, A. P. (2017) · Haematologica · doi:10.3324/haematol.2016.157206 · Cited by 22

Gene expression profiling of peripheral blood cells: new insights into Ewing sarcoma biology and clinical applications

Przybył, J., Kozak, K., Koseła-Paterczyk, H., Falkowski, S., Świtaj, T., Ługowska, I., Szumera‐Ciećkiewicz, A., Ptaszyński, K., Grygalewicz, B., Chechlińska, M., et al. (2014) · Medical Oncology · doi:10.1007/s12032-014-0109-2 · Cited by 22

Interactions between platelets and the cancer immune microenvironment

Tuerhong, N., Yang, Y., Wang, C., Huang, P., & Li, Q. (2024) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2024.104380 · Cited by 21

Regulation of the microglial polarization for alleviating neuroinflammation in the pathogenesis and therapeutics of major depressive disorder

Wang, Y., Chen, C.-Y., Lei, L., & Zhang, Y. (2025) · Life Sciences · doi:10.1016/j.lfs.2025.123373 · Cited by 22

Targeting Inflammatory Signaling in Prostate Cancer Castration Resistance

Zhong, S., Huang, C., Chen, Z., Chen, Z., & Luo, J. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10215000 · Cited by 20

Engineering CRISPR/Cas9 therapeutics for cancer precision medicine

Sharma, A. K., & Giri, A. K. (2024) · Frontiers in Genetics · doi:10.3389/fgene.2024.1309175 · Cited by 23

Role of tumor-associated macrophages in the Hexim1 and TGFβ/SMAD pathway, and their influence on progression of prostatic adenocarcinoma

Atılgan, A. O., Özdemir, B. H., Akçay, E. Y., Demirkan, Ö. A., Tekindal, M. A., & Özkardeş, H. (2015) · Pathology - Research and Practice · doi:10.1016/j.prp.2015.10.011 · Cited by 21

Structural characterization and immunostimulatory activity of polysaccharides from Pyrus sinkiangensis Yu

Zhou, K., Taoerdahong, H., Bai, J., Bakasi, A., Wang, X., & Dong, C. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.04.146 · Cited by 21

Revisiting the clinical usefulness of C-reactive protein in the set of cancer cachexia

Tavares, P., Moreira‐Gonçalves, D., Santos, L. L., & Ferreira, R. M. (2021) · Porto Biomedical Journal · doi:10.1097/j.pbj.0000000000000123 · Cited by 20

Identification and Validation of a Tumor Microenvironment‐Related Gene Signature for Prognostic Prediction in Advanced‐Stage Non‐Small‐Cell Lung Cancer

Zhang, X., Shi, X., Zhao, H., Jia, X., & Yang, Y. (2021) · BioMed Research International · doi:10.1155/2021/8864436 · Cited by 20

The immunoregulation effect of tumor microenvironment in pancreatic ductal adenocarcinoma

Zhang, J., Li, R., & Huang, S. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.951019 · Cited by 19

Absolute monocyte count in follicular lymphoma patients treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone

Watanabe, R., Tomita, N., Kishimoto, K., Koyama, S., Ogusa, E., Ishii, Y., Miyashita, K., Matsuura, S., Fujisawa, S., Hattori, Y., et al. (2013) · Leukemia Research · doi:10.1016/j.leukres.2013.07.015 · Cited by 20

Feedback mechanisms between M2 macrophages and Th17 cells in colorectal cancer patients

Mao, H., Pan, F., Guo, H., Bu, F., Xin, T., Chen, S., & Guo, Y. (2016) · Tumor Biology · doi:10.1007/s13277-016-5085-z · Cited by 20

Pretreatment Lymphocyte Monocyte Ratio Predicts Long-Term Outcomes in Patients with Digestive System Tumor: A Meta-Analysis

Zhang, J., Chen, L., Zhou, R., Sun, H., Liao, Y., & Liao, W. (2016) · Gastroenterology Research and Practice · doi:10.1155/2016/9801063 · Cited by 19

Association of ATF4 Expression With Tissue Hypoxia and M2 Macrophage Infiltration in Infantile Hemangioma

Xia, H.-F., Zhu, J., Wang, J., Ren, J., Cai, Y., Wang, F., Zhang, W., Chen, G., Zhao, Y., & Zhao, J. (2017) · Journal of Histochemistry & Cytochemistry · doi:10.1369/0022155417694872 · Cited by 20

The prognostic role of CD68 and FoxP3 expression in patients with primary central nervous system lymphoma

Cho, H., Kim, S. H., Kim, S., Chang, J. H., Yang, W. I., Suh, C., Cheong, J., Kim, Y. R., Lee, J. Y., Jang, J. E., et al. (2017) · Annals of Hematology · doi:10.1007/s00277-017-3014-x · Cited by 21

Human cytomegalovirus-mediated immunomodulation: Effects on glioblastoma progression

Foster, H., Ulasov, I. V., & Cobbs, C. (2017) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2017.05.006 · Cited by 20

Evaluation of the new anti-inflammatory compound ethyl salicylate 2-O-β-d-glucoside and its possible mechanism of action

Xin, W., Huang, C., Zhang, X., Zhang, G., Ma, X., Sun, L., Wang, C., Zhang, D., Zhang, T., & Du, G. (2012) · International Immunopharmacology · doi:10.1016/j.intimp.2012.11.014 · Cited by 20

AQP9 transports lactate in tumor-associated macrophages to stimulate an M2-like polarization that promotes colon cancer progression

Shi, Y., Yasui, M., & Hara‐Chikuma, M. (2022) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2022.101317 · Cited by 18

Magnetic nanoparticles and possible synergies with cold atmospheric plasma for cancer treatment

Dai, X., Dai, Y., Zheng, Y., & Lv, Y. (2024) · RSC Advances · doi:10.1039/d4ra03837a · Cited by 19

Carboxypeptidase M in apoptosis, adipogenesis and cancer

Denis, C. J., Deiteren, K., Hendriks, D. F., Proost, P., & Lambeir, A. (2012) · Clinica Chimica Acta · doi:10.1016/j.cca.2012.11.012 · Cited by 19

Many Roles of CCL20: Emphasis on Breast Cancer

Osuala, K. O., & Sloane, B. F. (2014) · Postdoc Journal · doi:10.14304/surya.jpr.v2n3.2 · Cited by 19

Cancer Immunotherapy: Targeting Tumor-Associated Macrophages by Gene Silencing

Zins, K., & Abraham, D. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0290-4_17 · Cited by 21

PD-1 expression is elevated in monocytes from hepatocellular carcinoma patients and contributes to CD8 T cell suppression

Jin, Y., Yu, G., Hu, P., Yang, C., Li, X., Chen, X., Wei, Q., & Wang, J. (2020) · Immunologic Research · doi:10.1007/s12026-020-09155-3 · Cited by 23

Specific changes in amino acid profiles in monocytes of patients with breast, lung, colorectal and ovarian cancers

Chagovets, V., Starodubtseva, N. L., Tokareva, A., Novoselova, A., Patysheva, M. R., Larionova, I., Prostakishina, E. A., Rakina, M. A., Казакова, А., Topolnitskiy, E. B., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1332043 · Cited by 19

Mechanisms underlying aryl hydrocarbon receptor-driven divergent macrophage function

Malany, K., Li, X., Vogel, C. F. A., & Ehrlich, A. K. (2024) · Toxicological Sciences · doi:10.1093/toxsci/kfae050 · Cited by 18

GdCl3 suppresses the malignant potential of hepatocellular carcinoma by inhibiting the expression of CD206 in tumor-associated macrophages

Zhu, F., Li, X., Jiang, Y. Q., Zhu, H., Zhang, H., Zhang, C., Zhao, Y., & Luo, F. (2015) · Oncology Reports · doi:10.3892/or.2015.4268 · Cited by 18

PKCζ in prostate cancer cells represses the recruitment and M2 polarization of macrophages in the prostate cancer microenvironment

Fan, H., Li, L., Zhang, Y.-M., Yang, J., Li, M.-C., Zeng, F., & Deng, F. (2017) · Tumor Biology · doi:10.1177/1010428317701442 · Cited by 18

Leukocyte infiltrate in gastrointestinal adenocarcinomas is strongly associated with tumor microsatellite instability but not with tumor immunogenicity

Bernal, M., Concha, Á., Sáenz-López, P., Rodríguez, A. I. E., Cabrera, T., Garrido, F., & Ruiz‐Cabello, F. (2011) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-011-0999-1 · Cited by 19

Activation of Murine Macrophages

Mosser, D. M., & Gonçalves, R. (2015) · Current Protocols in Immunology · doi:10.1002/0471142735.im1402s111 · Cited by 18

Melatonin modulates L-arginine metabolism in tumor-associated macrophages by targeting arginase 1 in lymphoma

Kumari, A., Syeda, S., Rawat, K., Kumari, R., & Shrivastava, A. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02676-2 · Cited by 17

Activated macrophages containing tumor marker in colon carcinoma: immunohistochemical proof of a concept

Faber, T. J. E., Japink, D., Leers, M. P. G., Sosef, M. N., MEYENFELDT, M. F. V., & Nap, M. (2011) · Tumor Biology · doi:10.1007/s13277-011-0269-z · Cited by 17

Inhibition of blood vessel formation in tumors by IL ‐18‐polarized M1 macrophages

Xing, Y., Tian, Y., Kurosawa, T., Matsui, S., Touma, M., Wu, Q., & Sugimoto, K. (2016) · Genes to Cells · doi:10.1111/gtc.12329 · Cited by 17

Context-Specific and Immune Cell-Dependent Antitumor Activities of α1-Antitrypsin

Guttman, O., Freixo-Lima, G. S., Kaner, Z., Lior, Y., Rider, P., & Lewis, E. C. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00559 · Cited by 17

Thalidomide suppresses breast cancer tumor growth by inhibiting tumor-associated macrophage accumulation in breast tumor-bearing mice

Wang, X., Shen, Y., MengLv, L., Zhang, X., Yang, J., Wang, F., & Yang, J. (2020) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2020.105302 · Cited by 17

Sweetpotato Leaves Inhibit Lipopolysaccharide-Induced Inflammation in RAW 264.7 Macrophages via Suppression of NF-κB Signaling Pathway

Cho, H.-D., Brownmiller, C., Sorker, H., Islam, S., & Lee, S. (2021) · Foods · doi:10.3390/foods10092051 · Cited by 14

A high pan-immune-inflammation value before chemoradiotherapy indicates poor outcomes in patients with small-cell lung cancer

Küçük, A., Topkan, E., Özkan, E. E., Öztürk, D., Pehlivan, B., & Selek, U. (2023) · International Journal of Immunopathology and Pharmacology · doi:10.1177/03946320231187759 · Cited by 16

Function and clinical application of exosome—how to improve tumor immunotherapy?

Qin, S., Cao, J., & Ma, X. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1228624 · Cited by 16

Identification of potential therapeutic targets for lung cancer by bioinformatics analysis

WANG, L.-Q., ZHAO, L.-H., & Qiao, Y.-Z. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4752 · Cited by 16

The prognostic value of preoperative inflammatory indexes in gallbladder carcinoma with hepatic involvement

Tao, Z., Li, S. X., Cui, X., Huang, Y., Zhu, S., Wang, Y., Tan, H., & Ma, X. (2018) · Cancer Biomarkers · doi:10.3233/cbm-181230 · Cited by 16

Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer

Tang, H., Zheng, J. Y., Bai, X., Yue, K.-L., Liang, J., Li, D., Wang, L., Wang, J., & Guo, Q. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.564298 · Cited by 16

Legumain protease-sheddable PEGylated, tuftsin-modified nanoparticles for selective targeting to tumour-associated macrophages

Liang, D.-S., Wen, Z.-J., Wang, J.-H., Zhu, F.-F., Guo, F., Zhou, J.-L., Xu, J.-J., & Zhong, H.-J. (2021) · Journal of drug targeting · doi:10.1080/1061186x.2021.1906886 · Cited by 15

Expression of IL-23R and IL-17 and the pathology and prognosis of urinary bladder carcinoma

Liu, J., Wang, L., Wang, T., & Wang, J. (2018) · Oncology Letters · doi:10.3892/ol.2018.9145 · Cited by 16

Human leukocyte antigen-DR expression on flow cytometry and tumor-associated macrophages in diffuse large B-cell lymphoma treated by rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone therapy: retrospective cohort study

Yamamoto, W., Nakamura, N., Tomita, N., Takeuchi, K., Ishii, Y., Takahashi, H., Watanabe, R., Takasaki, H., Motomura, S., Kobayashi, S., et al. (2014) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.3109/10428194.2014.893311 · Cited by 16

Chronic inflammation and gastrointestinal cancer

Watanabe, M., Ida, S., & Baba, H. (2015) · Journal of Cancer Metastasis and Treatment · doi:10.4103/2394-4722.166994 · Cited by 17

Tumor Macrophages

Qualls, J. E., & Murray, P. J. (2011) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-380916-2.00010-3 · Cited by 15

Interaction of Immune and Cancer Cells

Klink, M. (2013) · Springer eBooks · doi:10.1007/978-3-7091-1300-4 · Cited by 15

Mammalian Sterile 20-Like Kinase (MST) 1/2: Crucial Players in Nervous and Immune System and Neurological Disorders

Qi, Y., Sun, D., Yang, W., Xu, B., Lv, D., Han, Y., Sun, M., Jiang, S., Hu, W., & Yang, Y. (2020) · Journal of Molecular Biology · doi:10.1016/j.jmb.2020.03.010 · Cited by 15

Correlation of APE1 with VEGFA and CD163+ macrophage infiltration in bladder cancer and their prognostic significance

Wang, L.-A., Yang, B., Tang, T., Yang, Y., Zhang, D., Xiao, H., Xu, J., Wang, L., Lin, L. W., & Jiang, J. (2020) · Oncology Letters · doi:10.3892/ol.2020.11814 · Cited by 15

4-O-methylascochlorin attenuates inflammatory responses induced by lipopolysaccharide in RAW 264.7 macrophages

Lim, H., Park, J., Abekura, F., Choi, H., Kim, H.-D., Magae, J., Chang, Y., Lee, Y., & Kim, C. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.107184 · Cited by 14

M2a macrophages induce contact-dependent dispersion of carcinoma cell aggregates

(2016) · Macrophage · doi:10.14800/macrophage.1222 · Cited by 14

Tumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarization

Jiménez-García, L., Herranz, S., Higueras, M. Á., Luque, A., & Hortelano, S. (2016) · Oncotarget · doi:10.18632/oncotarget.11652 · Cited by 14

Preoperative platelet morphology parameters as prognostic predictors for endometrial malignant carcinoma stage and progesterone receptor

Song, J., Lai, X., Zhang, Y., Zheng, X., & Su, J. (2019) · Medicine · doi:10.1097/md.0000000000017818 · Cited by 14

Nomogram based on pre-treatment inflammatory biomarkers predicting survival in patients with head and neck soft tissue sarcoma

Chen, L., Zeng, H., Du, Z., Zhao, Y., & Ma, X. (2020) · Cancer Biomarkers · doi:10.3233/cbm-201739 · Cited by 14

Cyclin D1b induces changes in the macrophage phenotype resulting in promotion of tumor metastasis

Wang, Y., Liu, Y., Xiang, L., Han, L., Yao, X., Hu, Y., & Wu, F. (2021) · Experimental Biology and Medicine · doi:10.1177/15353702211038511 · Cited by 12

Human-derived Tumor-On-Chip model to study the heterogeneity of breast cancer tissue

Jeibouei, S., Monfared, A. K., Hojat, A., Aref, A. R., Shams, F., Dolati, M., Moradi, A., Hosseini, M., Javadi, S. M. R., Ajoudanian, M., et al. (2024) · Biomaterials Advances · doi:10.1016/j.bioadv.2024.213915 · Cited by 15

Surface antigen expression on peripheral blood monocytes in women with gynecologic malignancies

Jóźwik, M., Okungbowa, O. E., Lipska, A., Jóźwik, M., Smoktunowicz, M., Semczuk, A., Jóźwik, M., & Radziwon, P. (2015) · BMC Cancer · doi:10.1186/s12885-015-1136-x · Cited by 14

Association of Macrophages With Angiogenesis in Oral Epithelial Dysplasia, Oral Verrucous Carcinoma, and Oral Squamous Cell Carcinoma: An Immunohistochemical Study

Chawla, H., Urs, A. B., & Augustine, J. (2015) · Applied immunohistochemistry & molecular morphology · doi:10.1097/pai.0000000000000284 · Cited by 14

Preoperative lymphocyte-to-monocyte ratio predicts survival in primary hepatitis B-virus positive hepatocellular carcinoma after curative resection

Li, G., Ji, J., Yang, F., Xu, H., & Bai, Y. (2017) · OncoTargets and Therapy · doi:10.2147/ott.s110411 · Cited by 13

Alterations of Signaling Pathways Related to the Immune System in Breast Cancer: New Perspectives in Patient Management

Nicolini, A., Ferrari, P., Diodati, L., & Carpi, A. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092733 · Cited by 14

Myeloid cells

Toh, B., Toh, B., Abastado, J., & Abastado, J. (2012) · OncoImmunology · doi:10.4161/onci.22196 · Cited by 15

Tumor Biology and Metastasis

Argyle, D. J., & Khanna, C. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-2362-5.00002-5 · Cited by 14

Insulin resistance and metabolic dysfunction in thyroid nodules and differentiated thyroid cancer

Iuliano, S., Mirabelli, M., Giuliano, S., & Brunetti, A. (2025) · Current Opinion in Oncology · doi:10.1097/cco.0000000000001202 · Cited by 13

Ethnic disparities in the immune microenvironment of triple negative breast cancer and its role in therapeutic outcomes

Zajac, K. K., Malla, S., Babu, R. J., Raman, D., & Tiwari, A. K. (2023) · Cancer Reports · doi:10.1002/cnr2.1779 · Cited by 13

Macrophage Polarisation: A collaboration of Differentiation, Activation and Pre-Programming?

Foey, A. (2015) · Journal of Clinical & Cellular Immunology · doi:10.4172/2155-9899.1000293 · Cited by 13

Therapies Targeting Immune Cells in Tumor Microenvironment for Non-Small Cell Lung Cancer

Ye, W., Li, M., & Luo, K.-W. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15071788 · Cited by 14

Tumor Necrosis Factor (TNF) and Chemokines in Colitis-Associated Cancer

Mukaida, N., Sasakki, S.-I., & Popivanova, B. K. (2011) · Cancers · doi:10.3390/cancers3032811 · Cited by 13

Peritoneal GATA6 + macrophage drives hepatic immunopathogenesis and maintains the Treg cell niche in the liver

Chang, H., Ni, Y., Shen, C., Li, C., He, K., Zhu, X., Chen, L., Chen, L., Qiu, J., Ji, Y., et al. (2022) · Immunology · doi:10.1111/imm.13519 · Cited by 12

Synergistic effect of CD47 blockade in combination with cordycepin treatment against cancer

Chen, F., Chen, R., Fang, W., Gao, X., Ying, H., Zheng, X., Chen, L., & Jiang, J. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1144330 · Cited by 12

Mutation-specific effects of NRAS oncogenes in colorectal cancer cells

Kuhn, N. R., Klinger, B., Uhlitz, F., Sieber, A., Rivera, M., Klotz‐Noack, K., Fichtner, I., Hoffmann, J., Blüthgen, N., Falk, C. S., et al. (2020) · Advances in Biological Regulation · doi:10.1016/j.jbior.2020.100778 · Cited by 13

Anti-cancer activity of an ethanolic extract of red okra pods (Abelmoschus esculentus L. Moench) in rats induced by N-methyl-N-nitrosourea

Pramudya, M., Dewi, F. R. P., Wong, R. W.-C., Anggraini, D. W., Winarni, D., & Wahyuningsih, S. P. A. (2022) · Veterinary World · doi:10.14202/vetworld.2022.1177-1184 · Cited by 12

The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages.

Allavena, P., Sica, A., Solinas, G., Porta, C., & Mantovani, A. (2008) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2007.07.004 · Cited by 1,044

Tumor-associated Macrophages in Cancer Growth and Progression

Mantovani, A., Galdiero, M. R., Allavena, P., & Sica, A. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-394296-8.00027-0 · Cited by 1

Tumor-associated macrophages: role in tumorigenesis and immunotherapy implications

Zhu, S., Luo, Z., Li, X., Han, X., Shi, S., & Zhang, T. (2020) · Journal of Cancer · doi:10.7150/jca.49692 · Cited by 85

Role of tumour-associated macrophages in cancer-related inflammation.

Sica, A. (2010) · PubMed · Cited by 117

Tumor-Associated Macrophages

Allavena, P., & Belgiovine, C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-374279-7.17013-4 · Cited by 2