The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.
Antioxidant, antiradical, and antimicrobial activities of polysaccharides obtained by microwave-assisted extraction method: A review
Abstract
The antioxidant and antimicrobial activities of polysaccharides extracted by microwave-assisted extraction (MAE) were reviewed. An ascending dose-dependent manner was found for the in vitro antioxidant (e.g., nitrite scavenging, phospho-molybdenum reduction, inhibition of lipid peroxidation (ILP), ferric reducing power, and ferrous metal ions chelating), and antiradical (against DPPH, OH, ABTS, NO, and O 2 - ) activities. There was a positive and significant correlation between ILP and erythrocyte hemolysis inhibition, showing the excellent antioxidative properties to prevent the risk of cell damage. These carbohydrate-based polymers in vivo could reduce malonaldehyde and protein carbonyls and increase stress-resistance-related enzymes such as catalase, superoxide dismutase, and glutathione peroxidase. They showed an effective bactericidal activity against a wide variety of gram-negative and gram-positive bacterial infections. The in vitro strong antifungal and antiviral activities of sulfated polysaccharides extracted by MAE were also diagnosed without any cytotoxicity effect. Therefore, these biomacromolecules might be used to develop functional foods and nutraceuticals.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“MAE combined with RSM has several advantages compared with other advanced extraction technologies, such as higher extraction yield, improved selectivity, better handling, and low solvent consumption [12].”
From Optimized microwave-assisted azadirachtin extraction using response surface methodology (2024) · cites this paper as [12]
Citations
Cites
DPPH antioxidant assay revisited
Sharma, O. P., & Bhat, T. K. (2008) · Food Chemistry · doi:10.1016/j.foodchem.2008.08.008 · Cited by 2,046
Comparison of ABTS/DPPH assays to measure antioxidant capacity in popular antioxidant-rich US foods
Floegel, A., Kim, D., Chung, S., Koo, S. I., & Chun, O. K. (2011) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2011.01.008 · Cited by 1,818
Kaufmann, B., & Christen, P. (2002) · Phytochemical Analysis · doi:10.1002/pca.631 · Cited by 831
Reviews on Mechanisms of In Vitro Antioxidant Activity of Polysaccharides
Wang, J., Hu, S., Nie, S., Yu, Q., & Xie, M. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/5692852 · Cited by 727
Microwave-assisted extraction of sulfated polysaccharides (fucoidan) from brown seaweed
Rodriguez-Jasso, R. M., Mussatto, S. I., Pastrana, L., Aguilar, C. N., & Teixeira, J. A. (2011) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2011.06.006 · Cited by 434
Yuan, Y., & Macquarrie, D. (2015) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2015.04.057 · Cited by 371
Sun, L., Wang, C., Shi, Q., & Ma, C. (2009) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2009.03.013 · Cited by 338
Weber, D., Davies, M. J., & Grune, T. (2015) · Redox Biology · doi:10.1016/j.redox.2015.06.005 · Cited by 295
Yuan, Q., Lin, S., Fu, Y., Nie, X.-R., Liu, W., Su, Y., Han, Q.-H., Zhao, L., Zhang, Q. R., Lin, D., et al. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.01.042 · Cited by 292
Zhang, Q., Li, N., Zhou, G., Lu, X., Xu, Z., & Li, Z. (2003) · Pharmacological Research · doi:10.1016/s1043-6618(03)00103-8 · Cited by 253
Cited by
Sorted by citations
Items 301–337 of 337
ŞEKER EKSTRAKSİYONUNDA VURGULU ELEKTRİK ALAN UYGULAMA POTANSİYELİNİN DEĞERLENDİRİLMESİ
İşgüzar, E. E., & Fincan, M. (2023) · Gıda · doi:10.15237/gida.gd22125
Lam, K. K., Nguyen, T. B. T., Nguyen, T. H. N., Le, T. T. L., Sao, D., Dinh, M. H., & Ngo, D. (2023) · Ministry of Science and Technology Vietnam · doi:10.31276/vjste.65(2).65-70
Rollando, R., Monica, E., Afthoni, M. H., Kurniawan, C. D., & Sitepu, R. (2022) · Tropical Journal of Natural Product Research · doi:10.26538/tjnpr/v6i7.9
Optimized Microwave-Assisted Azadirachtin Extraction Using Response Surface Methodology (Rsm)Preprint
Martínez-Castro, R., Flórez-Santiago, J. J., Valle-Molinares, R., Cabrera-Barraza, J., Espitia-Almeida, F., & Espitia-Almeida, F. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4630775
Effects of LP on Immune Function and Intestinal Flora in Immunosuppressive MicePreprint
Hou, J., Hao, J., Zhong, M., Ren, J., Xu, W., & He, X. (2024) · Preprints.org · doi:10.20944/preprints202405.1767.v1
Quality Assessment and Evaluation of a Novel Polyherbal Formulation for Antioxidant Properties
Shah, Z., Pithadia, A. B., & Chakraborthy, G. S. (2025) · Journal of Natural Remedies · doi:10.18311/jnr/2025/42151
Zhou, H., Hu, P., Bi, M., Cai, Y., Han, H., & Wang, H. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5255010
Design of value chains for vegetable by- and secondary products biorefinery
Condezo‐Hoyos, L., Mendiola, J. A., Cortés-Avendaño, P., Ibañez, E., & Villamiel, M. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-28810-4.00004-9
Ma, W., Zhu, Y., Zhang, C., Zhang, T., & Sun, A. (2025) · Materials Today Communications · doi:10.1016/j.mtcomm.2025.114285
Moufaddel, A., Kartah, B. E., Monfalouti, H. E., & Bougrin, K. (2025) · Phytochemistry Reviews · doi:10.1007/s11101-025-10204-8 · Cited by 1
Yang, X., Zhao, Y., Tian, H., & Yang, L. (2025) · Sustainable Chemistry and Pharmacy · doi:10.1016/j.scp.2025.102293
Al-Ugaili, D. N., Alobaidi, K. H., Khan, M. N., Putra, A. I., Al‐Dossary, O., & Al‐Obaidi, J. R. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-30102-5.00001-6
Yang, X., Wang, X., Ma, Y., Liu, B., Yao, S., Qin, C., Wang, S., & Liang, C. (2025) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2025.120873
Plant-Derived Marine Polysaccharides in Oral Drug Delivery
Prajapati, V. D., Shrivstav, A., Valand, J., Dalal, R., Penemecha, K., & Gandhi, S. J. (2026) · Springer eBooks · doi:10.1007/978-981-95-4126-3_2
Su, Y., Qian, W., Cao, X., Wang, H., Lei, X., Gong, W., & Hu, J. (2026) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2026.102635 · Cited by 1
Recent Advances in Innovative Processing Technologies for Barley Grass as a Functional Food Resource
Zeng, S., Wang, B. L., He, Y., Lin, R., Yang, L., Lv, W., & Xiao, H. (2026) · Food Engineering Reviews · doi:10.1007/s12393-025-09431-8
Dai, K., Guo, W., Liu, S., Zhang, Y., Chen, J., Huang, J., & Huang, R. (2026) · Natural Product Research · doi:10.1080/14786419.2026.2626546
Qian, Y., Zhang, D., & Yan, C. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-40578-5.00014-3
Lou, Z., Cheng, X., Pei, Z., Liu, C., Zhu, Z., Liao, Y., Huang, H., Huang, R., & Li, Y. (2026) · Foods · doi:10.3390/foods15071116
Wu, J., Zhang, X., Song, Q., Huang, F., Li, T., Qin, Z., Li, L., Shi, F., Liu, H., & Zou, C. (2026) · Fishes · doi:10.3390/fishes11040197
Ali, A. M., El-Monaem, E. M. A., Ragab, A., Ouyang, X., Eltaweil, A. S., Eldin, M. S. M., Abdallah, M. H., Abdel-Motaleb, M., Hamed, A. M., Heydari, A., et al. (2026) · Diamond and Related Materials · doi:10.1016/j.diamond.2026.113636
Functional Roles of Mushroom-Derived Polysaccharides in Human Health
Garcia, J., Gouvinhas, I., Silva, J., Olo-Fontinha, E., & Alves, M. J. (2026) · Springer eBooks · doi:10.1007/978-981-95-7692-0_8
Zhang, J., Li, Q., Ma, M., Yang, J., 郑旺斌, Ma, Y., Chang, R., Wang, H., Wang, R., & Zhang, J. (2026) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.6c00699
Wang, Z., Hao, L., & Gao, Y. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1857689
Xu, M., Ma, H., Yuan, Y., Guo, J., Kang, J., Jie, W., & 杨云喜 (2026) · Food Chemistry X · doi:10.1016/j.fochx.2026.104103
Xiao, W., Gao, W., Geng, Y., Afraz, M. T., Zeng, X., & Han, Z. (2026) · Food Physics · doi:10.1016/j.foodp.2026.100102
Mei, X., Zou, H., Sui, Y., Xiong, T., Wang, Q., & Shi, J. (2026) · Food Science and Biotechnology · doi:10.1007/s10068-026-02277-8
Cao, D.-Q., Yan, Z.-W., Qing-yue, Z., & Zhang, W.-Y. (2026) · Separations · doi:10.3390/separations13080228
Zhang, A., Xie, B., Feng, B., Wu, C., Gao, J., & Tan, X. (2026) · Bioactive Carbohydrates and Dietary Fibre · doi:10.1016/j.bcdf.2026.100558
Wang, R. (2026) · Journal of Food Processing and Preservation · doi:10.1155/jfpp/4463629
Zhang, M., Hao, L., Wang, Z., Yang, H., Zhou, R., Jiang, G., & Wu, C. (2026) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2026.154838
Microwave-assisted extraction of polysaccharides
Raghunath, S., & Gharibzahedi, S. M. T. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-44049-6.00010-7
Pharmaceutical and biomedical applications of polysaccharides
Gharibzahedi, S. M. T. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-44049-6.00015-6
Cosmetic and personal care applications of polysaccharides
Fang, D., Shen, W., Wang, H., Cheng, N., Zhang, M., Han, S., Du, Z., & Zhang, Y. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-44049-6.00011-9
Oxidized phospholipids: evolution, signaling, cell death, and human diseases
Ouyang, S., Sun, W., Duan, W., Wu, Y.-P., Lin, X., Gong, H.-B., Sun, J., Luo, X., Niu, J., Li, K., et al. (2026) · 中国科学通报:英文版 · doi:10.1016/j.scib.2026.10.026
Green extraction of propolis using SFE, UAE, and MAE: bioactive recovery and applications
Putra, N. R., Irianto, I., Suharmiati, S., & Airlangga, B. (2026) · Journal of Apicultural Research · doi:10.1080/00218839.2026.2742615
Cui, M., Zhang, L., Tian, W., Zhang, L., Huang, Y., Kehai, L., & Yang, Y. (2026) · Carbohydrate Research · doi:10.1016/j.carres.2026.110134
Metadata
- Authors
- Mirzadeh, M., Arianejad, M. R., & Khedmat, L.
- Affiliations
- Qazvin University of Medical Sciences (IR)
- Tabriz University of Medical Sciences (IR)
- Baqiyatallah University of Medical Sciences (IR)
- Corresponding author
- Khedmat, Leila
- Venue
- Carbohydrate Polymers
- Publisher
- Elsevier BV
- Published
- 2020-02
- Volume
- 229
- Pages
- 115421
- ISSN
- 0144-8617 (ISSN-L)
- OpenAlex
- W2979284845
- Cited by
- 337
- References
- 110
- Citations by year
- 2026: 37 · 2025: 72 · 2024: 56 · 2023: 41 · 2022: 58 · 2021: 47 · 2020: 26
- FWCI
- 2.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Carbohydrate Polymers (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Pharmacology (medical) › Fungal Biology and Applications
- Keywords
- polysaccharides, microwave-assisted extraction, antioxidant activity, free radical scavenging, antimicrobial activity, lipid peroxidation inhibition, erythrocyte hemolysis, oxidative stress enzymes, sulfated polysaccharides, antifungal activity, antiviral activity, functional foods, nutraceuticals
- MeSH terms
- Animals, Anti-Infective Agents, Antioxidants, Humans, Microwaves, Polysaccharides
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review