Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

MicroRNAs: Target Recognition and Regulatory Functions

Bartel, D. P. (2009) · Cell · doi:10.1016/j.cell.2009.01.002 · Cited by 20,068

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948

Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets

Lewis, B. P., Burge, C. B., & Bartel, D. P. (2005) · Cell · doi:10.1016/j.cell.2004.12.035 · Cited by 11,855

Untitled work

(2008) · doi:10.1038/nrg2290 · Cited by 5,199

Alternative isoform regulation in human tissue transcriptomes

Wang, E. T., Sandberg, R., Luo, S., Khrebtukova, I., Zhang, L., Mayr, C., Kingsmore, S. F., Schroth, G. P., & Burge, C. B. (2008) · Nature · doi:10.1038/nature07509 · Cited by 5,181

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242606799 · Cited by 5,111

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Wightman, B., Ha, I., & Ruvkun, G. (1993) · Cell · doi:10.1016/0092-8674(93)90530-4 · Cited by 4,292

MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing

Grimson, A., Farh, K. K.-H., Johnston, W. K., Garrett-Engele, P., Lim, L. P., & Bartel, D. P. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.06.017 · Cited by 3,766

RAS Is Regulated by the let-7 MicroRNA Family

Johnson, S., Großhans, H., Shingara, J., Byrom, M., JARVIS, R., Cheng, A., Labourier, E., Reinert, K. L., Brown, D., & Slack, F. J. (2005) · Cell · doi:10.1016/j.cell.2005.01.014 · Cited by 3,699

A microRNA polycistron as a potential human oncogene

He, L., Thomson, J. M., Hemann, M. T., Hernando, E., Mu, D., Goodson, S. G., Powers, S., Cordon‐Cardo, C., Lowe, S. W., Hannon, G. J., et al. (2005) · Nature · doi:10.1038/nature03552 · Cited by 3,642

Activation and inhibition of nonsense-mediated mRNA decay control the abundance of alternative polyadenylation products

Kishor, A., Fritz, S. E., Haque, N., Ge, Z., Tunc, I., Yang, W., Zhu, J., & Hogg, J. R. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa491 · Cited by 29

Crosstalk of promoter and terminator during RNA polymerase II transcription cycle

Al-Husini, N., Medler, S., & Ansari, A. (2020) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2020.194657 · Cited by 28

Diverse cell-specific patterns of alternative polyadenylation in Drosophila

Lee, S., Chen, Y., Gillen, A. E., Taliaferro, J. M., Deplancke, B., Li, H., & Lai, E. C. (2022) · Nature Communications · doi:10.1038/s41467-022-32305-0 · Cited by 28

Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation

Xiao, M., Zhang, B., Li, Y., Gao, Q., Sun, W., & Chen, W. (2016) · Molecular Systems Biology · doi:10.15252/msb.20167375 · Cited by 27

Therapeutic targeting of CPSF3-dependent transcriptional termination in ovarian cancer

Shen, P., Ye, K., Xiang, H., Zhang, Z., He, Q., Zhang, X., Cai, M., Chen, J., Sun, Y., Lin, L., et al. (2023) · Science Advances · doi:10.1126/sciadv.adj0123 · Cited by 25

Downregulation of CPSF6 leads to global mRNA 3’ UTR shortening and enhanced antiviral immune responses

Ge, Y., Huang, J., Chen, R., Fu, Y., Ling, T., Ou, X., Rong, X., Cheng, Y., Lin, Y., Zhou, F., et al. (2024) · PLoS Pathogens · doi:10.1371/journal.ppat.1012061 · Cited by 27

Reduced Expression of Ribosomal Proteins Relieves MicroRNA-Mediated Repression

Janas, M. M., Wang, E. T., Love, T. M., Harris, A., Stevenson, K. E., Semmelmann, K., Shaffer, J. M., Chen, P., Doench, J. G., Subrahmanyam, Y. V. B. K., et al. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.04.008 · Cited by 27

The emerging roles of 3′ untranslated regions in cancer

Li, J., & Lü, X. (2013) · Cancer Letters · doi:10.1016/j.canlet.2013.05.034 · Cited by 27

Nonsense in the testis: multiple roles for nonsense-mediated decay revealed in male reproduction

MacDonald, C. C., & Grozdanov, P. N. (2017) · Biology of Reproduction · doi:10.1093/biolre/iox033 · Cited by 27

The Length of the Expressed 3′ UTR Is an Intermediate Molecular Phenotype Linking Genetic Variants to Complex Diseases

Mariella, E., Marotta, F., Grassi, E., Gilotto, S., & Provero, P. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00714 · Cited by 25

Genome-wide profiling reveals alternative polyadenylation of mRNA in human non-small cell lung cancer

Zhang, S., Zhang, X., Lei, W., Liang, J., Xu, Y., Liu, H., & Ma, S. (2019) · Journal of Translational Medicine · doi:10.1186/s12967-019-1986-0 · Cited by 27

Differential evolution in 3′UTRs leads to specific gene expression in Staphylococcus

Menendez-Gil, P., Caballero, C. J., Catalan‐Moreno, A., Irurzun, N., Barrio‐Hernandez, I., Caldelari, I., & Toledo‐Arana, A. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa047 · Cited by 27

Alternative 3′ UTRs play a widespread role in translation-independent mRNA association with the endoplasmic reticulum

Cheng, L. C., Zheng, D., Zhang, Q., Güvenek, A., Cheng, H., & Tian, B. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109407 · Cited by 27

An emerging role of the 5′ termini of mature tRNAs in human diseases: Current situation and prospects

Hu, Y., Cai, A., Xu, J., Feng, W., Wu, A., Liu, R., Cai, W., Chen, L., & Wang, F. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2021.166314 · Cited by 28

AGO-RBP crosstalk on target mRNAs: Implications in miRNA-guided gene silencing and cancer

Kakumani, P. K. (2022) · Translational Oncology · doi:10.1016/j.tranon.2022.101434 · Cited by 28

Pseudogene CYP4Z2P 3′UTR promotes angiogenesis in breast cancer

Zheng, L., Li, X., Gu, Y., Ma, Y., & Xi, T. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.09.112 · Cited by 27

α-MSH regulates intergenic splicing of MC1R and TUBB3 in human melanocytes

Dalziel, M., Kolesnichenko, M., das Neves, R. P., Iborra, F. J., Goding, C. R., & Furger, A. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq1125 · Cited by 28

Driving glioblastoma growth by alternative polyadenylation

Han, T., & Kim, J. K. (2014) · Cell Research · doi:10.1038/cr.2014.88 · Cited by 27

mRNA isoform diversity can obscure detection of miRNA-mediated control of translation

Clancy, J. L., Wei, G., Echner, N., Humphreys, D. T., Beilharz, T. H., & Preiß, T. (2011) · RNA · doi:10.1261/rna.2567611 · Cited by 27

Differential 3’ processing of specific transcripts expands regulatory and protein diversity across neuronal cell types

Jereb, S., Hwang, H., Otterloo, E. V., Govek, E., Fak, J. J., Yuan, Y., Hatten, M. E., & Darnell, R. B. (2018) · eLife · doi:10.7554/elife.34042 · Cited by 25

Alternative Polyadenylation Allows Differential Negative Feedback of Human miRNA miR-579 on Its Host Gene ZFR

Hinske, L. C., Galante, P. A. F., Limbeck, E., Möhnle, P., Parmigiani, R. B., Lucila Ohno-machado, A., Camargo, A. A., & Kreth, S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0121507 · Cited by 26

miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP

Huhn, D., Kousholt, A. N., Sørensen, C. S., & Sartori, A. A. (2014) · Oncogene · doi:10.1038/onc.2014.329 · Cited by 24

Retroviral strategy to stabilize viral RNA

Quek, B. L., & BEEMON, K. L. (2014) · Current Opinion in Microbiology · doi:10.1016/j.mib.2014.02.004 · Cited by 24

Systematic review of computational methods for identifying miRNA-mediated RNA-RNA crosstalk

Li, Y., Jin, X., Wang, Z., Li, X., Chen, H., Li, X., Yi, S., Zhang, Y., & Xu, J. (2017) · Briefings in Bioinformatics · doi:10.1093/bib/bbx137 · Cited by 26

HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif

Wu, Y. C., Chen, H., Chen, Y., Qu, L., Zhang, E., Wang, Z., Wu, Y., Yang, R., Mao, R., Lu, C., et al. (2019) · Aging · doi:10.18632/aging.101927 · Cited by 26

Animal-APAdb: a comprehensive animal alternative polyadenylation database

Jin, W., Zhu, Q., Yang, Y., Yang, W., Wang, D., Yang, J., Niu, X., Yu, D., & Gong, J. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa778 · Cited by 26

Advances in the Biological Functions and Mechanisms of miRNAs in the Development of Osteosarcoma

Dong, Z., Liao, Z., He, Y., Cheng-ye, W., Meng, Z., Qin, B., Xu, G., Li, Z., Sun, T., Wen, Y., et al. (2022) · Technology in Cancer Research & Treatment · doi:10.1177/15330338221117386 · Cited by 25

The glucose transporter 1 -GLUT1- from the white shrimp Litopenaeus vannamei is up-regulated during hypoxia

Martínez-Quintana, J. A., Peregrino-Uriarte, A. B., Gollas‐Galván, T., Gómez‐Jiménez, S., & Yepiz-Plascencia, G. M. (2014) · Molecular Biology Reports · doi:10.1007/s11033-014-3682-8 · Cited by 26

Personal genomes, quantitative dynamic omics and personalized medicine

Mias, G. I., & Snyder, M. P. (2013) · Quantitative Biology · doi:10.1007/s40484-013-0005-3 · Cited by 29

The MicroRNA miR-191 Supports T Cell Survival Following Common γ Chain Signaling

Lykken, E. A., & Li, Q.-J. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.741264 · Cited by 26

Star-PAP controlled alternative polyadenylation coupled poly(A) tail length regulates protein expression in hypertrophic heart

Parambil, S. A., Mohan, N., Francis, N., Laishram, R. S., & Anderson, R. A. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz875 · Cited by 25

Regulation of genes in the arachidonic acid metabolic pathway by RNA processing and RNA ‐mediated mechanisms

Lutz, C. S., & Cornett, A. L. (2013) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1183 · Cited by 25

The guide-RNA sequence dictates the slicing kinetics and conformational dynamics of the Argonaute silencing complex

Wang, P. Y., & Bartel, D. P. (2024) · Molecular Cell · doi:10.1016/j.molcel.2024.06.026 · Cited by 25

Systematic analysis of siRNA and mRNA features impacting fully chemically modified siRNA efficacy

Davis, S. M., Hildebrand, S. R., MacMillan, H. J., Monopoli, K. R., Buchwald, J. E., Sousa, J., Cooper, D., Ly, S., Echeverria, D., McHugh, N., et al. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf479 · Cited by 26

mRNA initiation and termination are spatially coordinated

Calvo-Roitberg, E., Carroll, C. L., Kim, G., Sanabria, V. C., Venev, S. V., Mick, S. T., Paquette, J. D., Urióstegui-Arcos, M., Dekker, J., Fiszbein, A., et al. (2025) · Science · doi:10.1126/science.ado8279 · Cited by 23

Accurate Profiling and Quantification of tRNA Fragments from RNA-Seq Data: A Vade Mecum for MINTmap

Loher, P., Telonis, A. G., & Rigoutsos, I. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-7339-2_16 · Cited by 25

Involved microRNAs in alternative polyadenylation intervene in breast cancer via regulation of cleavage factor “CFIm25”

Tamaddon, M., Shokri, G., Hosseini Rad, S. M. A., Rad, I., Emami Razavi, À., & Kouhkan, F. (2020) · Scientific Reports · doi:10.1038/s41598-020-68406-3 · Cited by 25

Lifelong Reduction in LDL (Low-Density Lipoprotein) Cholesterol due to a Gain-of-Function Mutation in LDLR

Bjornsson, E., Gunnarsdottir, K., Halldorsson, G. H., Sigurdsson, A., Arnadottir, G. A., Jonsson, H., Olafsdottir, E. F., Niehus, S., Kehr, B., Sveinbjörnsson, G., et al. (2021) · Circulation: Genomic and Precision Medicine · doi:10.1161/circgen.120.003029 · Cited by 23

Endogenous p53 expression in human and mouse is not regulated by its 3′UTR

Mitschka, S., & Mayr, C. (2021) · eLife · doi:10.7554/elife.65700 · Cited by 26

The role of RNA binding proteins in hepatocellular carcinoma

Zhang, K., Barry, A. E., Lamm, R. J., Patel, K., Schafer, M., & Dang, H. T. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114114 · Cited by 27

IKAROS: a multifunctional regulator of the polymerase II transcription cycle

Bottardi, S., Mavoungou, L. O., & Milot, É. (2015) · Trends in Genetics · doi:10.1016/j.tig.2015.05.003 · Cited by 25

The τCstF-64 Polyadenylation Protein Controls Genome Expression in Testis

Li, W., Yeh, H.-J., Shankarling, G. S., Ji, Z., Tian, B., & MacDonald, C. C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048373 · Cited by 24

Post-Transcriptional Control of Cytokine Gene Expression in Health and Disease

Khabar, K. S. A. (2014) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2013.0151 · Cited by 25

Differential MicroRNA Regulation Correlates with Alternative Polyadenylation Pattern between Breast Cancer and Normal Cells

Liaw, H.-H., Lin, C.-C., Juan, H., & Huang, H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056958 · Cited by 26

Integrin α3β1 Signaling through MEK/ERK Determines Alternative Polyadenylation of the MMP-9 mRNA Transcript in Immortalized Mouse Keratinocytes

Missan, D. S., Mitchell, K., Subbaram, S., & DiPersio, C. M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119539 · Cited by 26

IVT-SAPAS: Low-Input and Rapid Method for Sequencing Alternative Polyadenylation Sites

Fu, Y., Ge, Y., Sun, Y., Liang, J., Wan, L., Wu, X., & Xu, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0145477 · Cited by 25

Genome-wide profiling of the 3' ends of polyadenylated RNAs

Sanfilippo, P., Miura, P., & Lai, E. C. (2017) · Methods · doi:10.1016/j.ymeth.2017.06.003 · Cited by 25

The effects of alternative splicing on miRNA binding sites in bladder cancer

Han, S., Kim, D., Shivakumar, M., Lee, Y.-J., Garg, T. K., Miller, J. E., Kim, J. H., Kim, D., & Lee, Y. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190708 · Cited by 25

AOX1-Subfamily Gene Members in Olea europaea cv. “Galega Vulgar”—Gene Characterization and Expression of Transcripts during IBA-Induced in Vitro Adventitious Rooting

Velada, I., Grzebelus, D., Lousa, D., Soares, C. M., Macedo, E. S., Peixe, A., Arnholdt‐Schmitt, B., & Cardoso, H. G. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020597 · Cited by 25

Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms

Gruber, A. J., Gypas, F., Riba, A., Schmidt, R., & Zavolan, M. (2018) · Nature Methods · doi:10.1038/s41592-018-0114-z · Cited by 24

Cell type-specific termination of transcription by transposable element sequences

Conley, A. B., & Jordan, I. (2012) · Mobile DNA · doi:10.1186/1759-8753-3-15 · Cited by 25

The LIN28B–IMP1 post-transcriptional regulon has opposing effects on oncogenic signaling in the intestinePreprint

Chatterji, P., Hamilton, K. E., Liang, S., Andres, S. F., Wijeratne, H. R. S., Mizuno, R., Simon, L. A., Hicks, P. D., Foley, S. W., Pitarresi, J. R., et al. (2018) · Genes & Development · doi:10.1101/gad.314369.118 · Cited by 22

Transcription: the epicenter of gene expression

Guo, J. (2014) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b1400113 · Cited by 32

Accurate Mapping of Cleavage and Polyadenylation Sites by 3′ Region Extraction and Deep Sequencing

Hoque, M., Li, W., & Tian, B. (2014) · Methods in molecular biology · doi:10.1007/978-1-62703-971-0_10 · Cited by 24

Circular RNAs: epigenetic regulators in cancerous and noncancerous skin diseases

Abi, A., Farahani, N., Molavi, G., & Hayat, S. M. G. (2019) · Cancer Gene Therapy · doi:10.1038/s41417-019-0130-x · Cited by 25

Pathogenic diversity of RNA variants and RNA variation-associated factors in cancer development

Yang, H. D., & Nam, S. W. (2020) · Experimental & Molecular Medicine · doi:10.1038/s12276-020-0429-6 · Cited by 25

Aptardi predicts polyadenylation sites in sample-specific transcriptomes using high-throughput RNA sequencing and DNA sequence

Lusk, R., Stene, E., Banaei‐Kashani, F., Tabakoff, B., Kechris, K. J., & Saba, L. M. (2021) · Nature Communications · doi:10.1038/s41467-021-21894-x · Cited by 23

MicroRNA Targeting

Ghanbarian, H., Yıldız, M. T., & Tutar, Y. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1170-8_6 · Cited by 24

Spectrum of DNA mismatch repair failures viewed through the lens of cancer genomics and implications for therapy

Mas-Ponte, D., McCullough, M., & Supek, F. (2022) · Clinical Science · doi:10.1042/cs20210682 · Cited by 24

Regulating the regulator: a survey of mechanisms from transcription to translation controlling expression of mammalian cell cycle kinase Aurora A

Cacioppo, R., & Lindon, C. (2022) · Open Biology · doi:10.1098/rsob.220134 · Cited by 21

Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple-negative breast cancer

Sudhakaran, M., Navarrete, T. G., Mejía‐Guerra, M. K., Mukundi, E., Eubank, T. D., Erich Grotewold, A., Arango, D., & Doseff, A. I. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-06342-6 · Cited by 24

Role of alternative polyadenylation in epigenetic silencing and antisilencing

Ma, L., Guo, C., & Li, Q. Q. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321025111 · Cited by 24

Sequencing of first-strand cDNA library reveals full-length transcriptomes

Agarwal, S., Macfarlan, T. S., Sartor, M. A., & Iwase, S. (2015) · Nature Communications · doi:10.1038/ncomms7002 · Cited by 24

miR-Sens—a retroviral dual-luciferase reporter to detect microRNA activity in primary cells

Beillard, E. J., Ong, S. C., Giannakakis, A., Guccione, E., Vardy, L. A., & Voorhoeve, P. M. (2012) · RNA · doi:10.1261/rna.031831.111 · Cited by 24

A complex immunodeficiency is based on U1 snRNP‐mediated poly(A) site suppression

Langemeier, J., Schrom, E.-M., Rabner, A., Radtke, M., Zychlinski, D., Saborowski, A. L., Bohn, G., Mandel‐Gutfreund, Y., Bodem, J., Klein, C., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.252 · Cited by 25

T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system

Tamai, M., Inukai, T., Kojika, S., Abe, M., Kagami, K., Harama, D., Shinohara, T., Watanabe, A., Oshiro, H., Akahane, K., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-27767-6 · Cited by 24

Overexpression of eIF3D in Lung Adenocarcinoma Is a New Independent Prognostic Marker of Poor Survival

Wang, D., Jia, Y., Zheng, W., Li, C., & Cui, W. (2019) · Disease Markers · doi:10.1155/2019/6019637 · Cited by 24

SR proteins in cancer: function, regulation, and small inhibitor

Bei, M., & Xu, J. (2024) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-024-00594-6 · Cited by 25

Overexpressed HSF1 cancer signature genes cluster in human chromosome 8q

Zhang, C. Q., Williams, H., Prince, T. L., & Ho, E. S. (2017) · Human Genomics · doi:10.1186/s40246-017-0131-5 · Cited by 23

RECK isoforms have opposing effects on cell migration

Lee, H. N., Mitra, M., Bosompra, O., Corney, D. C., Johnson, E. L., Rashed, N., Ho, L. D., & Coller, H. A. (2018) · Molecular Biology of the Cell · doi:10.1091/mbc.e17-12-0708 · Cited by 23

IMP1 3′ UTR shortening enhances metastatic burden in colorectal cancer

Andres, S. F., Williams, K. N., Plesset, J. B., Headd, J. J., Mizuno, R., Chatterji, P., Lento, A., Klein–Szanto, A. J., Mick, R., Hamilton, K. E., et al. (2018) · Carcinogenesis · doi:10.1093/carcin/bgy153 · Cited by 22

RNA-biology ruling cancer progression? Focus on 3′UTRs and splicing

Erson-Bensan, A. E. (2020) · Cancer and Metastasis Reviews · doi:10.1007/s10555-020-09884-9 · Cited by 23

CstF64-Induced Shortening of the BID 3′UTR Promotes Esophageal Squamous Cell Carcinoma Progression by Disrupting ceRNA Cross-talk with ZFP36L2

Lin, A., Ji, P., Niu, X., Zhao, X., Chen, Y., Liu, W., Liu, Y., Fan, W., Sun, Y., Miao, C., et al. (2021) · Cancer Research · doi:10.1158/0008-5472.can-21-1201 · Cited by 23

The Crosstalk of Long Non-Coding RNA and MicroRNA in Castration-Resistant and Neuroendocrine Prostate Cancer: Their Interaction and Clinical Importance

Hu, C., Wu, K., Lin, T.-Y., & Chen, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010392 · Cited by 22

Regulation of neuronal RNA signatures by ELAV /Hu proteins

Hilgers, V. (2022) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1733 · Cited by 26

The androgen receptor messenger RNA: what do we know?

Likos, E., Bhattarai, A., Weyman, C. M., & Shukla, G. C. (2022) · RNA Biology · doi:10.1080/15476286.2022.2084839 · Cited by 28

Small RNAs in mammalian germline: Tiny for immortal

Tang, F. (2010) · Differentiation · doi:10.1016/j.diff.2009.11.002 · Cited by 23

Dynamic landscape of alternative polyadenylation during retinal development

Hu, W., Li, S., Park, J. Y., Boppana, S., Ni, T., Li, M., Zhu, J., Tian, B., Xie, Z., & Xiang, M. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2429-1 · Cited by 23

Molecular Regulation of Cellular Senescence by MicroRNAs: Implications in Cancer and Age-Related Diseases

Neault, M., Couteau, F., Bonneau, É., Guire, V. D., & Mallette, F. A. (2017) · International review of cytology · doi:10.1016/bs.ircmb.2017.04.001 · Cited by 23

MicroRNA Regulation of Telomerase Reverse Transcriptase (TERT): Micro Machines Pull Strings of Papier-Mâché Puppets

Farooqı, A. A., Mansoor, Q., Alaaeddine, N., & Xu, B. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19041051 · Cited by 23

Dicer loss and recovery induce an oncogenic switch driven by transcriptional activation of the oncofetal Imp1–3 familyPreprint

JnBaptiste, C. K., Gurtan, A. M., Thai, K. K., Lu, V., Bhutkar, A. J., Su, M.-J., Rotem, A., Jacks, T., & Sharp, P. A. (2017) · Genes & Development · doi:10.1101/gad.296301.117 · Cited by 23

A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types

Foord, C., Prjibelski, A. D., Hu, W., Michielsen, L., Vandelli, A., Narykov, O., Evans, B., Hsu, J., Belchikov, N., Jarroux, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63301-9 · Cited by 23

Regulation of gene expression by alternative polyadenylation in health and disease

Tian, B., Yu, S., & Zhang, Q. (2026) · Nature Reviews Genetics · doi:10.1038/s41576-025-00928-w · Cited by 23

PolyA-iEP: A data mining method for the effective prediction of polyadenylation sites

TZANIS, G. L., Kavakiotis, I., & Vlahavas, I. P. (2011) · Expert Systems with Applications · doi:10.1016/j.eswa.2011.04.019 · Cited by 22

Fine-tuning of microRNA-mediated repression of mRNA by splicing-regulated and highly repressive microRNA recognition element

Wu, C.-T., Chiou, C.-Y., Chiu, H.-C., & Yang, U. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-438 · Cited by 22

In vitro labeling strategies for in cellulo fluorescence microscopy of single ribonucleoprotein machines

Custer, T. C., & Walter, N. G. (2016) · Protein Science · doi:10.1002/pro.3108 · Cited by 20

Drivers of Gene Expression Dysregulation in Pancreatic Cancer

Venkat, S., Alahmari, A. A., & Feigin, M. E. (2021) · Trends in cancer · doi:10.1016/j.trecan.2021.01.008 · Cited by 23

Factors affecting the rapid changes of protein under short-term heat stress

Wu, B., Qiao, J., Wang, X., Liu, M., Xu, S., & Sun, D. (2021) · BMC Genomics · doi:10.1186/s12864-021-07560-y · Cited by 21

RNAs as Regulators of Cellular Matchmaking

Fernandes, N., & Buchan, J. R. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.634146 · Cited by 24

The S taufen 1 ‐dependent cell cycle regulon or how a misregulated RNA‐ binding protein leads to cancer

Bonnet‐Magnaval, F., & DesGroseillers, L. (2021) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12749 · Cited by 23

A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients

Zingone, A., Sinha, S., Ante, M., Nguyen, C. D., Daujotyte, D., Bowman, E. D., Sinha, N., Mitchell, K. A., Chen, Q., Yan, C., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-25763-5 · Cited by 25

Nutritional compensation of the circadian clock is a conserved process influenced by gene expression regulation and mRNA stability

Kelliher, C., Stevenson, E., Loros, J., & Dunlap, J. (2023) · PLoS Biology · doi:10.1371/journal.pbio.3001961 · Cited by 22

Downregulation of apoptotic repressor AVEN exacerbates cardiac injury after myocardial infarction

Yu, P. F., Song, S., Zhang, X., Cui, S., Wei, G., Huang, Z., Zeng, L., Ni, T., & Sun, A. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2302482120 · Cited by 24

Dynamic expression of 3′ UTRs revealed by Poisson hidden Markov modeling of RNA-Seq: Implications in gene expression profiling

Lu, J., & Bushel, P. R. (2013) · Gene · doi:10.1016/j.gene.2013.06.052 · Cited by 21

Let‐7 MicroRNA and HMGA2 levels of expression are not inversely linked in adipocytic tumors: Analysis of 56 lipomas and liposarcomas with molecular cytogenetic data

Bianchini, L., Saâda-Bouzid, E., Gjernes, E., Marty, M., Haudebourg, J., Birtwisle‐Peyrottes, I., Keslair, F., Chignon‐Sicard, B., Chamorey, E., & Pédeutour, F. (2011) · Genes Chromosomes and Cancer · doi:10.1002/gcc.20869 · Cited by 22

Mining Functional Elements in Messenger RNAs: Overview, Challenges, and Perspectives

Ahmed, F., Benedito, V. A., & Zhao, P. X. (2011) · Frontiers in Plant Science · doi:10.3389/fpls.2011.00084 · Cited by 22

The yeast RPL9B gene is regulated by modulation between two modes of transcription termination

Gudipati, R. K., Neil, H., Feuerbach, F., Malabat, C., & Jacquier, A. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.81 · Cited by 25

Meiosis-induced alterations in transcript architecture and noncoding RNA expression in S. cerevisiae

Guisbert, K. S. K., Zhang, Y., Flatow, J. M., Hurtado, S., Staley, J. P., Lin, S. M., & Sontheimer, E. J. (2012) · RNA · doi:10.1261/rna.030510.111 · Cited by 22

Sequence variations affecting AU-rich element function and disease

Hitti, E. (2011) · Frontiers in bioscience · doi:10.2741/4023 · Cited by 23

Regulation of alternative polyadenylation by Nkx2-5 and Xrn2 during mouse heart development

Nimura, K., Yamamoto, M., Takeichi, M., Saga, K., Takaoka, K., Kawamura, N., Nitta, H., Nagano, H., Ishino, S., Tanaka, T., et al. (2016) · eLife · doi:10.7554/elife.16030 · Cited by 22

UTR cutbacks give free rein to oncogenes

Atkinson, S. R. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2668 · Cited by 1

Lengthening of 3′ Untranslated Regions of mRNAs by Alternative Polyadenylation Is Associated With Tumor Progression and Poor Prognosis of Clear Cell Renal Cell Carcinoma

Zhang, F., Chen, L., Li, W., Yang, C., Xiong, M., Zhou, M., Kazobinka, G., Zhao, J., & Hou, T. (2023) · Laboratory Investigation · doi:10.1016/j.labinv.2023.100125 · Cited by 4

The 3′ UTR Landscape in Cancer

Schmidt, R., Ghosh, S., & Zavolan, M. (2018) · Wiley eBooks · doi:10.1002/9780470015902.a0027958 · Cited by 3

Resolving the complexity of the cancer transcriptome through 3’ UTRs

Erson-Bensan, A. E. (2017) · OpenMETU (Middle East Technical University)

Abstract A14: Alternative polyadenylation drives oncogenic gene expression in pancreatic cancer

Venkat, S., Tisdale, A. A., Eng, K. H., & Feigin, M. E. (2019) · Cancer Research · doi:10.1158/1538-7445.panca19-a14