The Somatic Genomic Landscape of Glioblastoma

Brennan, Cameron W., Verhaak, Roel G.W., McKenna, Aaron, Campos, Benito, Noushmehr, Houtan, Salama, Sofie R., Zheng, Siyuan, Chakravarty, Debyani +292 more·2013·Cell

DOI 10.1016/j.cell.2013.09.034

Cited by (1,018)

Items 901–1,000 of 1,018

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Jingxian Liu, Song Cao, Kathleen J. Imbach, Marina A. Gritsenko, T. Mamie Lih, Jennifer E Kyle, Tomer M. Yaron-Barir, Zev A. Binder, Yize Li, Ilya Strunilin et al. · 2024 · Cancer Cell
Proteomic analysis of cerebrospinal fluid: toward the identification of biomarkers for gliomas
Fang Shen, Yang Zhang, Yu Yao, Wei Hua, Hai-Shi Zhang, Jingsong Wu, Ping Zhong, Liangfu Zhou · 2014 · Neurosurgical Review
Noninvasive brain cancer imaging with a bispecific antibody fragment, generated via click chemistry
Haiming Luo, Reinier Hernandez, Hao Hong, Stephen A. Graves, Yunan Yang, Christopher G. England, Charles P. Theuer, Robert J. Nickles, Weibo Cai · 2015 · Proceedings of the National Academy of Sciences
A global assessment of cancer genomic alterations in epigenetic mechanisms
Muhammad Ahmad Shah, Emily Denton, C.H. Arrowsmith, Mathieu Lupien, Matthieu Schapira · 2014 · Epigenetics & Chromatin
Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells
Simona Camorani, Elvira Crescenzi, David Colecchia, Andrea Carpentieri, Angela Amoresano, Monica Fedele, Mario Chiariello, Laura Cerchia · 2015 · Oncotarget
Molecular mechanisms and therapeutic targets in pediatric brain tumors
Kun-Wei Liu, Kristian W. Pajtler, Barbara Christine Worst, Stefan Michael Pfister, Robert J. Wechsler‐Reya · 2017 · Science Signaling
Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target
Peter J. Cook, Rozario Thomas, Ram Kannan, Esther León, Alexander Edward Dela Cruz Drilon, Marc K. Rosenblum, Maurizio Scaltriti, Robert Benezra, Andrea Ventura · 2017 · Nature Communications
EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma
Zhenyi An, Christiane Brigitte Knobbe-Thomsen, Xiaohua Wan, Qi Wen Fan, Guido Reifenberger, William A. Weiss · 2018 · Cancer Research
Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma
Sarah M. Bronner, Karl A. Merrick, Jeremy M. Murray, Laurent Salphati, John G. Moffat, Jodie Pang, Christopher J. Sneeringer, Nicholas Dompe, Patrick Cyr, Hans E. Purkey et al. · 2019 · Bioorganic & Medicinal Chemistry Letters
Glioblastoma quo vadis : Will migration and invasiveness reemerge as therapeutic targets?
Florence Lefranc, Émilie Le Rhun, Robert Kiss A, Michael Weller · 2018 · Cancer Treatment Reviews
2-(2-(2,4-dioxopentan-3-ylidene)hydrazineyl)benzonitrile as novel inhibitor of receptor tyrosine kinase and PI3K/AKT/mTOR signaling pathway in glioblastoma
Anisha Viswanathan, Dinesh Kute, Aliyu Musa, Konda Mani Saravanan, Vili Sipilä, Frank Emmert‐Streib, Fedor Ivanovich Zubkov, Atash V. Gurbanov, Olli P. Yli-Harja, Meenakshisundaram Kandhavelu · 2019 · European Journal of Medicinal Chemistry
A RNA sequencing-based six-gene signature for survival prediction in patients with glioblastoma
Shuguang Zuo, Xinhong Zhang, Liping Wang · 2019 · Scientific Reports
Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity
Aron Gyuris, José Navarrete-Perea, Ala Jo, Simona Cristea, Shuang Zhou, Kyle B. Fraser, Zhiyun Wei, Anna M. Krichevsky, Ralph Weissleder, Hakho Lee et al. · 2019 · Cell Reports
Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer
Nicole Oatman, Nupur Dasgupta, Priyanka Arora, Kwangmin Choi, Mruniya V. Gawali, Nishtha Gupta, Sreeja Parameswaran, Joseph R. Salomone, Julie A. Reisz, Sean Edward Lawler et al. · 2021 · Science Advances
Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting
Zhenfang Du, Benjamin P. Brown, Soyeon Kim, Donna C. Ferguson, Dean C. Pavlick, Gowtham Jayakumaran, Ryma Benayed, Jean‐Nicolas Gallant, Yunkai Zhang, Yingjun Yan et al. · 2021 · Nature Communications
Oligosarcomas, IDH-mutant are distinct and aggressive
Abigail Kora Suwala, Marius Felix, Dennis Friedel, Damian Stichel, Daniel Schrimpf, Felix E. Hinz, Ekkehard Hewer, Leonille Schweizer, Hildegard Dohmen, Ute Pohl et al. · 2021 · Acta Neuropathologica
Comprehensive review of drug resistance in mammalian cancer stem cells: implications for cancer therapy
Bemrew Admassu Mengistu, Tirunesh Tsegaw, Yitayew Demessie, Kalkidan Getnet, Abebe Belete Bitew, Mebrie Zemene Kinde, Asnakew Mulaw Berihun, Atsede Solomon Mebratu, Yesuneh Tefera Mekasha, Melaku Getahun Feleke et al. · 2024 · Cancer Cell International
Oncostatin-M Differentially Regulates Mesenchymal and Proneural Signature Genes in Gliomas via STAT3 Signaling
Kumar Natesh, Dipali Bhosale, Aarti Desai, Goparaju Chandrika, Radha Pujari, Jayashree C. Jagtap, Ashish P. Chugh, Deepak Ranade, Padma Shastry · 2015 · Neoplasia
The cancer cell adhesion resistome: mechanisms, targeting and translational approaches
Ellen Dickreuter, Nils Cordes · 2016 · Biological Chemistry
The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures
Ravi S. Narayan, Carlos Alexandre Fedrigo, Eelke Brands, Rogier Dik, Lukas J.A. Stalpers, Brigitta G. Baumert, Ben J. Slotman, Bart A. Westerman, Godefridus J. Peters, Peter Sminia · 2017 · BMC Cancer
Clinical Identification of Oncogenic Drivers and Copy-Number Alterations in Pituitary Tumors
Wenya Linda Bi, Noah F. Greenwald, Shakti H Ramkissoon, Malak Abedalthagafi, Shannon Coy, Keith Lloyd Ligon, Yu Mei, Laura E. MacConaill, Matt Ducar, Le Min et al. · 2017 · Endocrinology
Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma
Sameer A. Greenall, Yi Chieh Lim, Camilla B. Mitchell, Kathleen S. Ensbey, Brett William Stringer, Alexander L. Wilding, Geraldine Margaret O’Neill, Kerrie Leanne McDonald, Daniel J. Gough, Bryan W. Day et al. · 2017 · Oncogenesis
Single-cell RNA-seq reveals a distinct transcriptome signature of aneuploid hematopoietic cells
Xin Zhao, Shouguo Gao, Zhijie Wu, Sachiko Kajigaya, Xingmin Feng, Qingguo Liu, Danielle Michelle Townsley, James Cooper, Jinguo Chen, Keyvan Keyvanfar et al. · 2017 · Blood
Increased level of H19 long noncoding RNA promotes invasion, angiogenesis, and stemness of glioblastoma cells
Xiaochun Jiang, Yukui Yan, Minghua Hu, Xiande Chen, Yaxian Wang, Yi Dai, Degang Wu, Yongsheng Wang, Zhixiang Zhuang, Hongping Xia · 2016 · Journal of neurosurgery
EZH2-, CHD4-, and IDH-linked epigenetic perturbation and its association with survival in glioma patients
Le Zhang, Ying Liu, Mengning Wang, Zhenhai Wu, Na Li, Jinsong Zhang, Chuanwei Yang · 2017 · Journal of Molecular Cell Biology
Identification of an energy metabolism-related signature associated with clinical prognosis in diffuse glioma
Zhengui Zhou, Ruoyu Huang, Ruichao Chai, Xiaohong Zhou, Zhiping Hu, Wenbiao Wang, Baoguo Chen, Lintao Deng, Yuqing Liu, Fan Wu · 2018 · Aging
Organoid models of glioblastoma: advances, applications and challenges.
Chaocai Zhang, Ming-Zhu Jin, Jiannong Zhao, Juxiang Chen, Weilin Jin · 2020 · PubMed Central
Current Perspective on the Natural Compounds and Drug Delivery Techniques in Glioblastoma Multiforme
Tapan Behl, Aditi Sharma, Lalit Kumar Sharma, Aayush Sehgal, Sukhbir Singh, Neelam Sharma, Gökhan Zengin, SIMONA GABRIELA BUNGAU, Mirela Mărioara Toma, Daniela Gîtea et al. · 2021 · Cancers
Advancing glioblastoma treatment by targeting metabolism
Jinyi Zhao, Xue-Mei Ma, Peixian Gao, Xueqi Han, Pengxiang Zhao, Fei Xie, Mengyu Liu · 2024 · Neoplasia
Peptide vaccines for the treatment of glioblastoma
Adam M. Swartz, Kristen A. Batich, Peter Edward Fecci, John Howard Sampson · 2014 · Journal of Neuro-Oncology
Loss of ATRX, associated with DNA methylation pattern of chromosome end, impacted biological behaviors of astrocytic tumors
Jinquan Cai, Jing Chen, Wei Zhang, Pei Yang, Chuanbao Zhang, Mingyang Li, Kun Yao, Hongjun Wang, Qingbin Li, Chuanlu Jiang et al. · 2015 · Oncotarget
Predicting cancer type from tumour DNA signatures
Kee Pang Soh, Ewa Szczurek, Thomas Sakoparnig, Niko Beerenwinkel · 2017 · Genome Medicine
Glioblastoma: new therapeutic strategies to address cellular and genomic complexity
Xue Cai, Michael E. Sughrue · 2017 · Oncotarget
A cancer tissue-specific FAM72 expression profile defines a novel glioblastoma multiform (GBM) gene-mutation signature
Chinmay Satish Rahane, Arne Kutzner, Klaus Heese · 2018 · Journal of Neuro-Oncology
Evolutionary Routes in Metastatic Uveal Melanomas Depend on MBD4 Alterations
Manuel Jorge Rodrigues, Lenha Mobuchon, Alexandre Houy, Samar Alsafadi, Sylvain Baulande, Odette Mariani, Benjamin Marande, Khadija Aït Raïs, Monique K. van der Kooij, Ellen Kapiteijn et al. · 2019 · Clinical Cancer Research
EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma
Nina Struve, Zev A. Binder, Lucy F. Stead, Tim Brend, Stephen Joseph Bagley, Claire Faulkner, Leonie Florence Ott, Justus Müller-Goebel, Anna-Sophie Weik, Konstantin Hoffer et al. · 2020 · Oncogene
DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development
Hans Binder, Edith Willscher, Henry Loeffler‐Wirth, Lydia Hopp, David Jones, Stefan Michael Pfister, Markus Kreuz, Dorothee Gramatzki, Erik Fortenbacher, Bettina Hentschel et al. · 2019 · Acta Neuropathologica Communications
Transcriptome profiling-based identification of prognostic subtypes and multi-omics signatures of glioblastoma
Junseong Park, Jin‐Kyoung Shim, Seon‐Jin Yoon, Se Hoon Kim, Jong Hee Chang, Seok‐Gu Kang · 2019 · Scientific Reports
Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma
Zhihong Chen, Nishant Soni, Gonzalo Piñero, Bruno Giotti, Devon James Eddins, Katherine E. Lindblad, James Ross, Montserrat Puigdelloses Vallcorba, Tanvi V. Joshi, Angelo Angione et al. · 2023 · Nature Communications
Mutational profiling of kinases in glioblastoma
Fonnet E. Bleeker, Simona Lamba, Carlo Zanon, Remco Jurriaan Molenaar, Theo J.M. Hulsebos, Dirk Troost, Angela A. van Tilborg, William Peter Vandertop, Sieger Leenstra, Cornelis J.F. Van Noorden et al. · 2014 · BMC Cancer
Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas
Lei Zhang, Soumi Kundu, Tjerk Feenstra, Xiujuan Li, Chuan Jin, Liisi Laaniste, Tamador Elsir Abu El Hassan, K. Elisabet Ohlin, Di Yu, Tommie Olofsson et al. · 2015 · Science Signaling
Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
Yiwen Jiang, Voichita Dana Marinescu, Yuan Xie, Malin Jarvius, Naga Prathyusha Maturi, Caroline Haglund, Sara K. Olofsson, Nanna Lindberg, Tommie Olofsson, Caroline Leijonmarck et al. · 2017 · Cell Reports
EGFR/EGFRvIII Dual-Targeting Peptide-Mediated Drug Delivery for Enhanced Glioma Therapy
Jiani Mao, Danni Ran, Cao Xie, Qing Shen, Songli Wang, Weiyue Lu · 2017 · ACS Applied Materials & Interfaces
A prospective study of serum metabolites and glioma risk
Jiaqi Huang, Stephanie J. Weinstein, Cari Meinhold Kitahara, Edward D. Karoly, Joshua Neil Sampson, Demetrius Albanes · 2017 · Oncotarget
The Spatial and Genomic Hierarchy of Tumor Ecosystems Revealed by Single-Cell Technologies
Eric A. Smith, H. Courtney Hodges · 2019 · Trends in cancer
Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas
Valya Ramakrishnan, Beibei Xu, Johnny C. Akers, Thien Phuc Nguyen, Jun Ma, Sanjay Dhawan, Jianfang Ning, Ying Qing Mao, Wei Hua, Efrosini Kokkoli et al. · 2020 · EBioMedicine
Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor
Calixto-Hope G. Lucas, Rohit K. Gupta, Pamela Doo, Julieann C. Lee, Cathryn René Cadwell, Biswarathan Ramani, Jeffrey W. Hofmann, Emily A. Sloan, Bette Kay Kleinschmidt-DeMasters, Han S. Lee et al. · 2020 · Acta Neuropathologica Communications
TCF12 is mutated in anaplastic oligodendroglioma
Karim Labrèche, Iva Simeonova, Aurélie Kamoun, Vincent Gleize, Daniel Chubb, Éric Letouzé, Yasser Riazalhosseini, Sara E. Dobbins, Nabila Elarouci, François Ducray et al. · 2015 · Nature Communications
Genetic driver mutations define the expression signature and microenvironmental composition of high‐grade gliomas
C. J. Herting, Z. Chen, Kenneth L. Pitter, Frank Szulzewsky, Ioannis Kaffes, Milota Kaluzová, J. C. Park, Patrick Joseph Cimino, Cameron Walter Brennan, B. Wang et al. · 2017 · Glia
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Ella L. Kim, Maxim Sorokin, Sven Rainer Kantelhardt, Darius Kalasauskas, Bettina Sprang, Julian Fauß, Florian A. Ringel, Andrew Garazha, Eugene A. Albert, Нуршат Гайфуллин et al. · 2020 · Cancers
Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling
Zhenlin Wang, Yuping Shi, Chenting Ying, Yang Jiang, Jiangfeng Hu · 2021 · Oncogene
Extrachromosomal Circular DNAs: Origin, formation and emerging function in Cancer
Man Wang, Xinzhe Chen, Fei Yu, Han Ding, Yuan Zhang, Kun Wang · 2021 · International Journal of Biological Sciences
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Jixing Zhao, Weili Jin, Kaikai Yi, Qixue Wang, Junhu Zhou, Yanli Tan, Can Xu, Menglin Xiao, Biao Hong, Fenfen Xu et al. · 2021 · Pharmacological Research
The HIF1α-PDGFD-PDGFRα axis controls glioblastoma growth at normoxia/mild-hypoxia and confers sensitivity to targeted therapy by echinomycin
Gong Peng, Yin Wang, Pengfei Ge, Christopher M. Bailey, Peng Zhang, Di Zhang, Zhaoli Meng, Chong Qi, Qian Chen, Jingtao Chen et al. · 2021 · Journal of Experimental & Clinical Cancer Research
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Daniel J. Brat, Kenneth Aldape, Julia A. Bridge, Peter Canoll, Howard Colman, Meera R. Hameed, Brent T. Harris, Eyas M. Hattab, Jason T. Huse, Robert Brian Jenkins et al. · 2022 · Archives of Pathology & Laboratory Medicine
High Expression of Glycolytic Genes in Clinical Glioblastoma Patients Correlates With Lower Survival
Kimberly M. Stanke, Carrick Wilson, Srivatsan Kidambi · 2021 · Frontiers in Molecular Biosciences
Cohesin gene mutations in tumorigenesis: from discovery to clinical significance
David A. Solomon, Jung-Sik Kim, Todd A. Waldman · 2014 · BMB Reports
A comprehensive next generation sequencing-based virome assessment in brain tissue suggests no major virus - tumor association
Michael J. Strong, Eugene Blanchard, Zhen Nan Lin, Cindy A. Morris, Melody Baddoo, Christopher M. Taylor, Marcus L. Ware, Erik K. Flemington · 2016 · Acta Neuropathologica Communications
A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS
Valeria Amodeo, Deli A, Joanne Betts, Stefano Bartesaghi, Ying Zhang, Angela Richard-Loendt, Matthew J. Ellis, Rozita Roshani, Mikaella Vouri, Sara Galavotti et al. · 2017 · Cell Reports
Genetic Evolution of Glioblastoma Stem-Like Cells From Primary to Recurrent Tumor
Francesca Orzan, Francesca De Bacco, Giovanni Crisafulli, Serena Pellegatta, Benedetta Mussolin, Giulia Siravegna, Antonio D’Ambrosio, Paolo Maria Comoglio, Gaetano Finocchiaro, Carla Boccaccio · 2017 · Stem Cells
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Inan Olmez, Ying Zhang, Laryssa C. Manigat, Mouadh Benamar, Breanna R. Brenneman, Ichiro Nakano, Jakub A. Godlewski, Agnieszka Bronisz, Jeongwu Lee, Tarek Abbas et al. · 2018 · Cancer Research
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Akgül, Seçkin, Patch, Ann-Marie, D’Souza, Rochelle C.J., Mukhopadhyay, Pamela, Nones, Katia, Kempe, Sarah, Kazakoff, Stephen H., Jeffree, Rosalind L., Stringer, Brett W., Pearson, John V. et al. · 2019 · Cancers
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Richard E. Phillips, Yanhong Yang, Ryan C. Smith, Bonne M. Thompson, Tomoko Yamasaki, Yadira M. Soto‐Feliciano, Kosuke Funato, Yupu Liang, Javier García‐Bermúdez, Xiaoshi Wang et al. · 2019 · Proceedings of the National Academy of Sciences
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Ailiang Zeng, Zhiyun Wei, Rosalia Rabinovsky, Hyun Jung Jun, Rachid El Fatimy, Evgeny Deforzh, Ramil Arora, Yizheng Yao, Shun Yao, Wei Yan et al. · 2020 · iScience
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Yang Liu, Fengchao Lang, Fu-Ju Chou, Kareem A. Zaghloul, Chunzhang Yang · 2020 · Biomedicines
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Jin-Zhu Wang, Hong Zhu, Pu You, Hui Liu, Wei-Kang Wang, Xiaojuan Fan, Yun Yang, Keren Xu, Yingfeng Zhu, Qunyi Li et al. · 2022 · Journal of Clinical Investigation
Emerging Perspectives on the Antiparasitic Mebendazole as a Repurposed Drug for the Treatment of Brain Cancers
Daniela Meco, Giorgio Attinà, Stefano Mastrangelo, Pierluigi Navarra, Antonio Ruggiero · 2023 · International Journal of Molecular Sciences
Identification of intrinsic subtype-specific prognostic microRNAs in primary glioblastoma
Rui Li, Kaiming Gao, Hui Luo, Xiefeng Wang, Yan Shi, Qingsheng Dong, Wenkang Luan, Yongping You · 2014 · Journal of Experimental & Clinical Cancer Research
Cancer type‐dependent genetic interactions between cancer driver alterations indicate plasticity of epistasis across cell types
Solip Park, Ben Lehner · 2015 · Molecular Systems Biology
Prediction of clinical outcome in glioblastoma using a biologically relevant nine‐microRNA signature
Josie L. Hayes, Helene Hoegsbro Thygesen, Charlotte Alicia Tumilson, Alastair Droop, Marjorie Boissinot, Thomas A. Hughes, David R. Westhead, Jane Elizabeth Alder, Lisa Shaw, Susan C Short et al. · 2014 · Molecular Oncology
Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients
Christine Jungk, Despina Chatziaslanidou, Rezvan Ahmadi, David Capper, Justo Lorenzo Bermejo, Janina Exner, Andreas von Deimling, Christel C. Herold‐Mende, Andreas Wilhelm Unterberg · 2016 · BMC Cancer
NOS Expression and NO Function in Glioma and Implications for Patient Therapies
Anh Nhat Tran, Nathaniel Boyd, Kiera D. Walker, Anita B. Hjelmeland · 2016 · Antioxidants and Redox Signaling
Rapid Clinical and Radiographic Response With Combined Dabrafenib and Trametinib in Adults With BRAF -Mutated High-Grade Glioma
Tanner Michael Johanns, Cole Ferguson, Patrick M. Grierson, Sonika M Dahiya, George Ansstas · 2018 · Journal of the National Comprehensive Cancer Network
YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity
Yu, Olivia M., Benitez, Jorge A., Plouffe, Steven W., Ryback, Daniel, Klein, Andrea, Smith, Jeff, Greenbaum, Jason, Delatte, Benjamin, Rao, Anjana, Guan, Kun-Liang et al. · 2018 · Oncogene
Luteolin Decreases Epidermal Growth Factor Receptor‐Mediated Cell Proliferation and Induces Apoptosis in Glioblastoma Cell Lines
David M. Anson, Rachel M. Wilcox, Eric D. Huseman, Trevor A. Stump, Robert L. Paris, Belinda O Darkwah, Stacy Lin, Andrea O. Adegoke, Rebecca J. Gryka, Denise Jean‐Louis et al. · 2018 · Basic & Clinical Pharmacology & Toxicology
Eribulin penetrates brain tumor tissue and prolongs survival of mice harboring intracerebral glioblastoma xenografts
Masamichi Takahashi, Shunichiro Miki, Kenji Fujimoto, Kohei Fukuoka, Yuko Matsushita, Yoshiko Maida, Mami Yasukawa, Mitsuhiro Hayashi, Raku Shinkyo, Kiyomi Kikuchi et al. · 2019 · Cancer Science
A pan-cancer analysis of prognostic genes
Jordan Anaya, Brian J. Reon, Wei‐Min Chen, Stefan Bekiranov, Anindya Dutta · 2016 · PeerJ
The protein arginine methyltransferase PRMT5 confers therapeutic resistance to mTOR inhibition in glioblastoma
Brent Holmes, Angelica Benavides-Serrato, Jacquelyn T. Saunders, Kenna A. Landon, Adam J Schreck, Robert N. Nishimura, Joseph Gera · 2019 · Journal of Neuro-Oncology
A 4-miRNA signature predicts the therapeutic outcome of glioblastoma
Maximilian Niyazi, Adriana Pitea, Michel Guy André Mittelbronn, Jörg Steinbach, Carsten Sticht, Franz Zehentmayr, D. Piehlmaier, Horst F. Zitzelsberger, Ute Ganswindt, Claus Michael Rödel et al. · 2016 · Oncotarget
The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells
Maria Grazia Atzori, Lucio Tentori, Federica Ruffini, Claudia Ceci, Lucia Lisi, Elena Bonanno, Manuel Scimeca, Eskil Eskilsson, Thomas Daubon, Hrvoje Miletić et al. · 2017 · Journal of Experimental & Clinical Cancer Research
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Jaione Auzmendi-Iriarte, Ander Saenz‐Antoñanzas, Idoia Mikelez-Alonso, Estefanía Carrasco‐García, Maitena Tellaetxe-Abete, Charles Henderson Lawrie, Nicolàs Samprón, Aitziber L. Cortajarena, Ander Matheu · 2020 · Cell Death and Disease
Beyond IDH-Mutation: Emerging Molecular Diagnostic and Prognostic Features in Adult Diffuse Gliomas
Kanish Mirchia, Timothy E. Richardson · 2020 · Cancers
Drug Repurposing for Glioblastoma and Current Advances in Drug Delivery—A Comprehensive Review of the Literature
Safwan Alomari, Irma Zhang, Adrian Hernandez, Caitlyn N. Kraft, Divyaansh Raj, Jayanidhi N. Kedda, Betty Tyler · 2021 · Biomolecules
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Abdellatif El Khayari, Najat Bouchmaa, Bouchra Taïb, Zhiyun Wei, Ailiang Zeng, Rachid El Fatimy · 2022 · Frontiers in Oncology
An atlas of late prenatal human neurodevelopment resolved by single-nucleus transcriptomics
Susana Isabel Ramos, Zarmeen M. Mussa, Elisa N. Falk, Balagopal Pai, Bruno Giotti, Kimaada Allette, Peiwen Cai, Fumiko Dekio, Robert Sebra, Kristin G. Beaumont et al. · 2022 · Nature Communications
Oncogene expression from extrachromosomal DNA is driven by copy number amplification and does not require spatial clustering in glioblastoma stem cells
Karin R. Purshouse, Elias T. Friman, Shelagh Boyle, Pooran Singh Dewari, Vivien Grant, Alhafidz Hamdan, Gillian M. Morrison, Paul Martin Brennan, Sjoerd Viktor Beentjes, Steven M. Pollard et al. · 2022 · eLife
Aptamer‐functionalized quantum dots as theranostic nanotools against cancer and bacterial infections: A comprehensive overview of recent trends
Fatemeh Davodabadi, Shekoufeh Mirinejad, Sonia Fathi‐karkan, Mahdi Majidpour, Narges Ajalli, Roghayeh Sheervalilou, Saman Sargazi, Dominika Rozmus, Abbas Rahdar, Ana Maria Diez-Pascual · 2023 · Biotechnology Progress
Expression level ofhTERTis regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma
Chul‐Kee Park, Se‐Hoon Lee, Ji Young Kim, Ja‐Eun Kim, Tae Min Kim, Soon‐Tae Lee, Seung Hong Choi, Sung‐Hye Park, Il Han Kim · 2014 · Oncotarget
CD40/CD40L expression correlates with the survival of patients with glioblastomas and an augmentation in CD40 signaling enhances the efficacy of vaccinations against glioma models
Masashi Chonan, Ryuta Saito, Takuhiro Shoji, Ichiyo Shibahara, Masayuki Kanamori, Yukihiko Sonoda, Mika Watanabe, Toshiaki Kikuchi, Naoto Ishii, Teiji Tominaga · 2015 · Neuro-Oncology
Targeting Therapeutic Liabilities Engendered by PIK3R1 Mutations for Cancer Treatment
Lydia W.T. Cheung, Gordon Brent Mills · 2016 · Pharmacogenomics
Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma
Qingqing Zhou, Athena Phoa, Ramzi H. Abbassi, Monira Hoque, Tristan A. Reekie, Josep S. Font, Renae M. Ryan, Brett William Stringer, Bryan W. Day, Terrance G. Johns et al. · 2017 · Journal of Medicinal Chemistry
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma
Robert S. McNeill, Demitra A. Canoutas, Timothy Joseph Stuhlmiller, Harshil Dhruv, David Irvin, Ryan Bash, Steven P. Angus, Laura E. Herring, Jeremy M. Simon, Kasey Skinner et al. · 2017 · Neuro-Oncology
Therapeutic Targeting of Histone Modifications in Adult and Pediatric High-Grade Glioma
Maria J. Williams, William Singleton, Stephen P. Lowis, Karim T. A. Malik, Kathreena Mary Kurian · 2017 · Frontiers in Oncology
Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma
H. Nakashima, Nguyen Tran, K. Kasai, Carmela Passaro, Hirotaka Ito, W. Goins, I. Shaikh, R. Erdelyi, R. Nishihara, I. Nakano et al. · 2018 · Clinical Cancer Research
The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres
Andrew S. Gilder, Letizia Natali, Danielle M. Van Dyk, Cristina Zalfa, Michael A. Banki, Donald P. Pizzo, Huawei Wang, Richard L. Klemke, Elisabetta Mantuano, Steven L. Gonias · 2018 · Scientific Reports
Prognostic impact of CDKN2A/B deletion, TERT mutation, and EGFR amplification on histological and molecular IDH-wildtype glioblastoma
Si‐Rui Ma, Soumon F. Rudra, Jian Li Campian, Sonika M Dahiya, Gavin P. Dunn, Tanner Michael Johanns, Michael Goldstein, Albert H. Kim, Jiayi Huang · 2020 · Neuro-Oncology Advances
Genetic and epigenetic alterations of micro RNA s and implications for human cancers and other diseases
Musaffe Tuna, Andreia S. Machado, George A. Călin · 2015 · Genes Chromosomes and Cancer
Temozolomide promotes genomic and phenotypic changes in glioblastoma cells
Aleksei A. Stepanenko, Svitlana V. Andreieva, Kateryna V. Korets, Dmytro O. Mykytenko, Vladimir P. Baklaushev, Nataliya L. Huleyuk, О. А. Ковальова, Kateryna Kotsarenko, Vladimir Pavlovich Chekhonin, Yegor S Vassetzky et al. · 2016 · Cancer Cell International
Microchip-based single-cell functional proteomics for biomedical applications
Yao Lu, Yang Liu, Wei Wei, Qihui Shi · 2017 · Lab on a Chip
Histone H3 Mutations in Cancer
Yi Ching Esther Wan, Jiaxian Liu, Kui Ming Chan · 2018 · Current Pharmacology Reports