The Somatic Genomic Landscape of Glioblastoma

Brennan, Cameron W., Verhaak, Roel G.W., McKenna, Aaron, Campos, Benito, Noushmehr, Houtan, Salama, Sofie R., Zheng, Siyuan, Chakravarty, Debyani +292 more·2013·Cell

DOI 10.1016/j.cell.2013.09.034

Cited by (1,018)

Items 601–700 of 1,018

Cancer aneuploidies are shaped primarily by effects on tumour fitness
Juliann Shih, Shahab Sarmashghi, Nadja Zhakula-Kostadinova, Shu Zhang, Yohanna Georgis, Stephanie H. Hoyt, Michael S. Cuoco, Galen F. Gao, Liam Flinn Spurr, Ashton C. Berger et al. · 2023 · Nature
Conpair: concordance and contamination estimator for matched tumor–normal pairs
Ewa A. Bergmann, Bo‐Juen Chen, Kanika S. Arora, Vladimir Vacic, Michael C. Zody · 2016 · Bioinformatics
Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression Level
Rebecca L. Klank, Stacy A. Decker, Benjamin L. Bangasser, Colleen L. Forster, Matthew A. Price, Thomas J. Odde, Karen Sterling SantaCruz, Steven S. Rosenfeld, Peter Canoll, Eva Ann Turley et al. · 2017 · Cell Reports
Oncogenic signaling pathways associated with immune evasion and resistance to immune checkpoint inhibitors in cancer
Yoshie Kobayashi, Seung‐Oe Lim, Hirohito Yamaguchi · 2019 · Seminars in Cancer Biology
Current Approaches for Glioma Gene Therapy and Virotherapy
Kaushik Banerjee, Felipe Javier Núñez, Santiago Haase, Brandon L. McClellan, Syed Mohd Faisal, Stephen V. Carney, Jin Yü, Mahmoud S. Alghamri, Antonela Sofía Asad, Alejandro J. Nicola Candia et al. · 2021 · Frontiers in Molecular Neuroscience
Genetic Alterations of TRAF Proteins in Human Cancers
Sining Zhu, Juan Jin, Samantha Gokhale, Angeli M. Lu, Haiyan Shan, Jian‐Jun Feng, Ping Xie · 2018 · Frontiers in Immunology
Signaling pathways in brain tumors and therapeutic interventions
Shenglan Li, Can Wang, Jinyi Chen, Yanjie Lan, Weichunbai Zhang, Zhuang Kang, Yi Zheng, Rong Zhang, Jianyu Yu, Wenbin Li · 2023 · Signal Transduction and Targeted Therapy
Complex Relationship between Ligand Binding and Dimerization in the Epidermal Growth Factor Receptor
Nicholas J. Bessman, Atrish Bagchi, Kathryn M. Ferguson, Mark A. Lemmon · 2014 · Cell Reports
Extrachromosomal driver mutations in glioblastoma and low-grade glioma
Sergey I. Nikolaev, Federico Andrea Santoni, Marco Garieri, Periklis Makrythanasis, Emilie Falconnet, Michel Guipponi, Anne Vannier, Ivan Radovanovic, Frederique Sloan Bena, Françoise Forestier et al. · 2014 · Nature Communications
Role of ketogenic metabolic therapy in malignant glioma: A systematic review
Sebastian Friedrich Winter, Franziska Loebel, Jörg Dietrich · 2017 · Critical Reviews in Oncology/Hematology
Molecular and Microenvironmental Determinants of Glioma Stem-Like Cell Survival and Invasion
Alison Roos, Zonghui Ding, Joseph C. Loftus, Nhan L. Tran · 2017 · Frontiers in Oncology
Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21
Quinn T. Ostrom, Ben Kinnersley, Margaret Wrensch, Jeanette E. Eckel‐Passow, Georgina Armstrong, Terri Rice, Yanwen Chen, John K. Wiencke, Lucie S. Mccoy, Helen M. Hansen et al. · 2018 · Scientific Reports
Cholesterol Metabolism: A Potential Therapeutic Target in Glioblastoma
Fahim Ahmad, Qian Sun, Deven Patel, Jayne M. Stommel · 2019 · Cancers
Dissecting the mechanism of temozolomide resistance and its association with the regulatory roles of intracellular reactive oxygen species in glioblastoma
Chia-Hung Chien, Wei‐Ting Hsueh, Jian‐Ying Chuang, Kwang‐Yu Chang · 2021 · Journal of Biomedical Science
Molecular Subtypes of Glioblastoma Are Relevant to Lower Grade Glioma
Xiaowei Guan, Jaime E. Vengoechea, Siyuan Zheng, Andrew Edward Sloan, Yanwen Chen, Daniel Jay Brat, Brian Patrick O’Neill, John de Groot, Shlomit Yust‐Katz, Wai-Kwan Alfred Yung et al. · 2014 · PLoS ONE
Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma
David J. Voce, Giovanna M. Bernal, Longtao Wu, Clayton D. Crawley, Wei Zhang, Nassir M. Mansour, Kirk E. Cahill, Szymon J. Szymura, Abhineet Uppal, David Ronan Raleigh et al. · 2019 · Cancer Research
Microenvironmental Heterogeneity in Brain Malignancies
Lucas J. M. Perus, Logan A. Walsh · 2019 · Frontiers in Immunology
An Upstream Open Reading Frame in Phosphatase and Tensin Homolog Encodes a Circuit Breaker of Lactate Metabolism
Nunu Huang, Fanying Li, Maolei Zhang, Huangkai Zhou, Zhipeng Chen, Xiaoyan Ma, Lixuan Yang, Xujia Wu, Jian Zhong, Feizhe Xiao et al. · 2021 · Cell Metabolism
Unravelling glioblastoma heterogeneity by means of single-cell RNA sequencing
Ana Hernández Martínez, Rodrigo Madurga, Noemí Garcia‐Romero, Ángel Ayuso‐Sacido · 2021 · Cancer Letters
BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network
Xueqin Sherine Sun, Olaf Klingbeil, Bin Lu, Caizhi Wu, Carlos Ballon, Meng Ouyang, Xiaoli Wu, Ying Jin, Yon Hwangbo, Yuhan Huang et al. · 2022 · Nature
From the core to beyond the margin: a genomic picture of glioblastoma intratumor heterogeneity
Marc Aubry, Marie de Tayrac, Amandine Etcheverry, Anne Clavreul, Stéphan Saïkali, Philippe Meneï, Jean Mosser · 2015 · Oncotarget
Liquid biopsies in patients with diffuse glioma
Myron G. Best, Nik Sol, Sebastiaan Zijl, Jaap C. Reijneveld, Pieter Wesseling, Thomas Würdinger · 2015 · Acta Neuropathologica
A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways
Tianzhi Huang, Angel A. Alvarez, Rajendra P. Pangeni, Craig Horbinski, Songjian Lu, Sung-Hak Kim, Charles David James, Jeffery J. Raizer, John A. Kessler, Cameron Brenann et al. · 2016 · Nature Communications
Treatment-Induced Mutagenesis and Selective Pressures Sculpt Cancer Evolution
Subramanian Venkatesan, Charles Swanton, Barry S. Taylor, J Costello · 2017 · Cold Spring Harbor Perspectives in Medicine
Belonging to a network—microRNAs, extracellular vesicles, and the glioblastoma microenvironment
Jakub A. Godlewski, Anna M. Krichevsky, Mark D. Johnson, Ennio Antonio Chiocca, Agnieszka Bronisz · 2014 · Neuro-Oncology
Problems of glioblastoma multiforme drug resistance
A. A. Stavrovskaya, Шушанов Саин Сакенович, Ekaterina Yu. Rybalkina · 2016 · Biochemistry (Moscow)
Radiomics in Brain Tumors
Aikaterini Kotrotsou, Pascal Olivier Zinn, Rivka R. Colen · 2016 · Magnetic Resonance Imaging Clinics of North America
Subtype-specific signaling pathways and genomic aberrations associated with prognosis of glioblastoma
Ae Kyung Park, Pora Kim, Leomar Y. Ballester, Yoshua Esquenazi, Zhongming Zhao · 2018 · Neuro-Oncology
DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in glioma
Xiangqi Meng, Chunbin Duan, Hengyuan Pang, Qun Chen, Bo Ram Han, Caijun Zha, Magafurov Dinislam, Pengfei Wu, Ziwei Li, Shihong Zhao et al. · 2019 · EBioMedicine
Genome‐Wide CRISPR‐Cas9 Screening Identifies NF‐κB/E2F6 Responsible for EGFRvIII‐Associated Temozolomide Resistance in Glioblastoma
Kai Huang, Xing Liu, Yansheng Li, Qixue Wang, Junhu Zhou, Yunfei Wang, Feng Dong, Chao Yang, Zhiyan Sun, Chuan Fang et al. · 2019 · Advanced Science
Molecular and Clinical Insights into the Invasive Capacity of Glioblastoma Cells
Carlos Velásquez, Sheila Mansouri, Carla Mora, Farshad Nassiri, Suganth Suppiah, Juan Martino, Gelareh Mohammed Zadeh, José L. Fernández-Luna · 2019 · Journal of Oncology
Updates in IDH-Wildtype Glioblastoma
Jawad M. Melhem, Jay S. Detsky, Mary Jane Lim-Fat, James Perry · 2022 · Neurotherapeutics
Emerging Role of Glioma Stem Cells in Mechanisms of Therapy Resistance
Frank Eckerdt, Leonidas C. Platanias · 2023 · Cancers
Tumour-wide RNA splicing aberrations generate actionable public neoantigens
Darwin W. Kwok, Nicholas O. Stevers, Iñaki Etxeberría, Takahide Nejo, Maggie Colton Cove, Lee H. Chen, Jangham Jung, Kaori Okada, Senthilnath Lakshmanachetty, Marco Gallus et al. · 2025 · Nature
Phase I dose-escalation study of the PI3K/mTOR inhibitor voxtalisib (SAR245409, XL765) plus temozolomide with or without radiotherapy in patients with high-grade glioma
Patrick Yung Wen, Antonio M. P. Omuro, Manmeet Singh Ahluwalia, Hassan M. Fathallah‐Shaykh, Nimish A. Mohile, Joanne J. Lager, Alexander Laird, Jiali Tang, Jason Jiang, Coumaran Égile et al. · 2015 · Neuro-Oncology
Elucidating the cancer-specific genetic alteration spectrum of glioblastoma derived cell lines from whole exome and RNA sequencing
Vikas S. Patil, Jagriti Pal, Kumaravel Somasundaram · 2015 · Oncotarget
Human TERT promoter mutation enables survival advantage from MGMT promoter methylation in IDH1 wild-type primary glioblastoma treated by standard chemoradiotherapy
HuyTram N. Nguyen, Amy Lie, Tie Li, Reshmi Chowdhury, Fei Liu, Byram Hirsch Ozer, Bowen Wei, Richard M. Green, Benjamin M. Ellingson, He-Jing Wang et al. · 2016 · Neuro-Oncology
Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia
Damian A. Almiron Bonnin, Matthew C. Havrda, Myung Chang Lee, H Liu, Z Zhang, Lananh Nguyen, Lia X. Harrington, Saeed Hassanpour, Chao Cheng, Mark A. Israel · 2017 · Oncogene
Drug Repositioning for Cancer Therapy Based on Large-Scale Drug-Induced Transcriptional Signatures
Haeseung Lee, Seungmin Kang, Wankyu Kim · 2016 · PLoS ONE
The prognostic value of MGMT promoter status by pyrosequencing assay for glioblastoma patients’ survival: a meta-analysis
Hai-Long Zhao, Shuying Wang, Cheng-Wei Song, Yun-Hong Zha, Li Li · 2016 · World Journal of Surgical Oncology
Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma
Dinesh Kumar Singh, Rahul Krishna Kollipara, Vamsidara Vemireddy, Xiao-Li Yang, Yuxiao Sun, Nanda L. Regmi, Stefan Klingler, Kimmo J. Hatanpaa, Jack M. Raisanen, Steve K. Cho et al. · 2017 · Cell Reports
The pro-tumorigenic effects of metabolic alterations in glioblastoma including brain tumor initiating cells
Catherine J. Libby, Anh Nhat Tran, Sarah E. Scott, Corinne E. Griguer, Anita B. Hjelmeland · 2018 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
Petri Pölönen, Ashik Jawahar Deen, Hanna M. Leinonen, Henna-Kaisa Jyrkkänen, Suvi Linna-Kuosmanen, Mimmi Mononen, Ashish Jain, Tomi Tuomainen, Sanna Pasonen‐Seppänen, Jaana M. Hartikainen et al. · 2019 · Oncogene
High-grade gliomas in adolescents and young adults highlight histomolecular differences from their adult and pediatric counterparts
Alexandre Roux, Johan Pallud, Raphaël Saffroy, Myriam Edjlali, Marie-Anne Debily, Nathalie Boddaert, Marc Sanson, Stéphanie Puget, Steven Knafo, Clovis Adam et al. · 2020 · Neuro-Oncology
Gliomas Interact with Non-glioma Brain Cells via Extracellular Vesicles
Xiaofei Gao, Zhaohuan Zhang, Tomoyuki Mashimo, Bo Shen, James O. Nyagilo, Hao Wang, Yihui Wang, Zhida Liu, Aditi Mulgaonkar, Xiao-Ling Hu et al. · 2020 · Cell Reports
Glutamatergic Mechanisms in Glioblastoma and Tumor-Associated Epilepsy
Falko Lange, Max Frederik Hörnschemeyer, Timo Kirschstein · 2021 · Cells
Importance of the intersection of age and sex to understand variation in incidence and survival for primary malignant gliomas
Gi-Ming Wang, Gino Cioffi, Nirav T. Patil, Kristin A. Waite, Robert Lanese, Quinn T. Ostrom, Carol A. Kruchko, Michael E. Berens, James R. Connor, Justin Durla Lathia et al. · 2021 · Neuro-Oncology
Glioblastoma vaccines: past, present, and opportunities
Zujian Xiong, Itay Raphael, Michael R. Olin, Hideho Okada, Xuejun Li, Gary Kohanbash · 2024 · EBioMedicine
In Vivo Detection of EGFRvIII in Glioblastoma via Perfusion Magnetic Resonance Imaging Signature Consistent with Deep Peritumoral Infiltration: The ϕ -Index
Spyridon Bakas, Hamed Akbari, Jared M. Pisapia, Maria Martinez‐Lage, Martin Rozycki, Saima Rathore, Nadia Dahmane, Donald M. O’Rourke, Christos A. Davatzikos · 2017 · Clinical Cancer Research
Genome sequencing in the clinic: the past, present, and future of genomic medicine
Jeremy W. Prokop, Thomas May, Kim A. Strong, Stephanie M. Bilinovich, Caleb P. Bupp, Surender Rajasekaran, Elizabeth A. Worthey, Jozef Lazar · 2018 · Physiological Genomics
A cytoskeleton regulator AVIL drives tumorigenesis in glioblastoma
Zhongqiu Xie, Pawel Ł. Janczyk, Ying Zhang, Aiqun Liu, Xinrui Shi, Sandeep Singh, Loryn Facemire, Kristopher E. Kubow, Zi Li, Yuemeng Jia et al. · 2020 · Nature Communications
FOSL1 promotes proneural-to-mesenchymal transition of glioblastoma stem cells via UBC9/CYLD/NF-κB axis
Zhengxin Chen, Shuai Wang, Hailin Li, Hui Luo, Xiaoting Wu, Jia‐Cheng Lu, Hongwei Wang, Yuanyuan Chen, Dan Chen, Wenting Wu et al. · 2022 · Molecular Therapy
The Evolving Molecular Genetics of Low-grade Glioma
Sriram Venneti, Jason T. Huse · 2015 · Advances in Anatomic Pathology
Protein expression of TTF1 and cMYC define distinct molecular subgroups of small cell lung cancer with unique vulnerabilities to aurora kinase inhibition, DLL3 targeting, and other targeted therapies
Robert J. Cardnell, Lerong Li, Triparna Sen, Rasha O. Bara, Pan Tong, Junya Fujimoto, Abbie S. Ireland, Matthew R. Guthrie, Sheila Bheddah, Upasana Banerjee et al. · 2017 · Oncotarget
Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations
Zachary Miklja, Amy L. Pasternak, Stefanie Stallard, Theodore P. Nicolaides, Cassie Kline-Nunnally, Bonnie Cole, Rameen Beroukhim, Pratiti Bandopadhayay, Susan N Chi, Shakti H Ramkissoon et al. · 2019 · Neuro-Oncology
GBP2 enhances glioblastoma invasion through Stat3/fibronectin pathway
Shuye Yu, Xiaoting Yu, Lili Sun, Yanwen Zheng, Lili Chen, Hui Xu, Jing Jin, Qing Lan, Clark C. Chen, Ming Li · 2020 · Oncogene
A serum-based DNA methylation assay provides accurate detection of glioma
Thaís S. Sabedot, Tathiane Maistro Malta, James Snyder, Kevin K. Nelson, Michael Wells, Ana C. deCarvalho, Abir Mukherjee, Dhananjay Arun Chitale, Maritza S. Mosella, Artem Sokolov et al. · 2021 · Neuro-Oncology
Therapeutic strategies of glioblastoma (GBM): The current advances in the molecular targets and bioactive small molecule compounds
Hui Liu, Weimin Qiu, Tianyu Sun, Lei Wang, Chenxi Du, Yanyu Hu, Wenyuan Liu, Feng Feng, Chen Yao, Haopeng Sun · 2021 · Acta Pharmaceutica Sinica B
Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
Hye-Min Jeon, Jeong‐Yub Kim, Hee Jin Cho, Won Jun Lee, Dayna Nguyen, Sung Soo Kim, Young Taek Oh, Hee‐Jin Kim, Chan‐Woong Jung, Gonzalo Piñero et al. · 2023 · Cancer Cell
Transcriptional diversity of long-term glioblastoma survivors
Naamit Kurshan Gerber, Anuj Goenka, Şevin Turcan, Marsha Reyngold, Vladimir Makarov, Kasthuri S. Kannan, Kathryn P. Beal, Antonio M. P. Omuro, Yoshiya Josh Yamada, Philip H. Gutin et al. · 2014 · Neuro-Oncology
Metabolic/Proteomic Signature Defines Two Glioblastoma Subtypes With Different Clinical Outcome
Giovanna Marziali, Michele Signore, Mariachiara Buccarelli, Sveva Grande, Alessandra Palma, Mauro Biffoni, Antonella Rosi, Quintino Giorgio D’Alessandris, Maurizio Martini, Luigi Maria Larocca et al. · 2016 · Scientific Reports
Receptor tyrosine kinases: biological functions and anticancer targeted therapy
Nan Zhang, Yongsheng Li · 2023 · MedComm
PI3K–mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models
Fan Lin, Mark C. de Gooijer, Diana Hanekamp, Gayathri Chandrasekaran, Levi C.M. Buil, Nishita Thota, Rolf W. Sparidans, Jos H. Beijnen, Tom Würdinger, Olaf van Tellingen · 2016 · Clinical Cancer Research
Extracellular Vesicles from Neurosurgical Aspirates Identifies Chaperonin Containing TCP1 Subunit 6A as a Potential Glioblastoma Biomarker with Prognostic Significance
Susannah M. Hallal, Benjamin P. Russell, Heng Wei, Maggie Yuk T. Lee, Christopher W. Toon, Joanne S. Sy, Brindha Shivalingam, Michael E. Buckland, Kimberley L. Alexander · 2018 · PROTEOMICS
P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib
Mark C. de Gooijer, Ping Zhang, Nishita Thota, Isabel Mayayo‐Peralta, Levi C.M. Buil, Jos H. Beijnen, Olaf van Tellingen · 2015 · Investigational New Drugs
Updates in prognostic markers for gliomas
Elisa Aquilanti, Julie J. Miller, Sandro Santagata, Daniel P. Cahill, Priscilla Kaliopi Brastianos · 2018 · Neuro-Oncology
Evolutionary dynamics of residual disease in human glioblastoma
Inmaculada Spiteri, Giulio Caravagna, George D. Cresswell, Alexandra I. Vatsiou, Daniel Nichol, Ahmet Acar, Luca Ermini, Kate Chkhaidze, Benjamin Werner, Richard James Mair et al. · 2018 · Annals of Oncology
TGF‐β‐activated lncRNA LINC00115 is a critical regulator of glioma stem‐like cell tumorigenicity
Jianming Tang, Bo Yu, Yanxin Li, Weiwei Zhang, Angel A. Alvarez, Bo Hu, Shi‐Yuan Cheng, Haizhong Feng · 2019 · EMBO Reports
Glioblastoma in adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
Patrick Yung Wen, Michael Weller, Eudocia Q. Lee, Mehdi Touat, Mustafa Khasraw, Rifaquat M. Rahman, Michael Platten, Michael K. Lim, Frank Winkler, Craig Horbinski et al. · 2025 · Neuro-Oncology
Drug repurposing for the treatment of glioblastoma multiforme
Claudia Abbruzzese, Silvia Matteoni, Michele Signore, Luca Cardone, Kavindra Nath, Jerry D. Glickson, Marco Giorgio Paggi · 2017 · Journal of Experimental & Clinical Cancer Research
High-Throughput Flow Cytometry Screening Reveals a Role for Junctional Adhesion Molecule A as a Cancer Stem Cell Maintenance Factor
Justin Durla Lathia, Meizhang Li, Maksim Sinyuk, Alvaro G. Alvarado, William A. Flavahan, Kevin Stoltz, Ann Mari Rosager, James S. Hale, Masahiro Hitomi, Joseph Gallagher et al. · 2014 · Cell Reports
The role of E3 ubiquitin ligases in the development and progression of glioblastoma
Luke M. Humphreys, Paul Smith, Zhuoyao Chen, Shahd Fouad, Vincenzo D’Angiolella · 2021 · Cell Death and Differentiation
Single-Cell Transcriptomic Analysis Revealed a Critical Role of SPP1/CD44-Mediated Crosstalk Between Macrophages and Cancer Cells in Glioma
Cong He, Luoyan Sheng, Deshen Pan, Shuai Jiang, Li Ding, Xiaojun Ma, Yaohua Liu, Deshui Jia · 2021 · Frontiers in Cell and Developmental Biology
Impact of age and gender on glioblastoma onset, progression, and management
Ambra Colopi, Serena Fuda, Samuele Santi, Angelo Onorato, Valeriana Cesarini, Maurizio Salvati, Carmela Rita Balistreri, Susanna Dolci, Eugenia Guida · 2023 · Mechanisms of Ageing and Development
Parallel microfluidic chemosensitivity testing on individual slice cultures
Tim C. Chang, Andrei M. Mikheev, Wilson Huynh, Raymond J. Monnat, Robert Rostomily, Albert Folch · 2014 · Lab on a Chip
Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6
Eunyoung Park, Nayoung Kim, Scott B. Ficarro, Yi Zhang, Byung Il Lee, Ahye Cho, Kihong Kim, Angela Kyung-Joo Park, Woong‐Yang Park, Bradley A. Murray et al. · 2015 · Nature Structural & Molecular Biology
Clonal Architectures and Driver Mutations in Metastatic Melanomas
Li Ding, Minjung Kim, Krishna Kanchi, Nathan D. Dees, Charles Lu, Malachi Griffith, David Fenstermacher, Hyeran Sung, Christopher A. Miller, Brian D. Goetz et al. · 2014 · PLoS ONE
Cell-intrinsic, Bmal1-dependent Circadian Regulation of Temozolomide Sensitivity in Glioblastoma
Emily A. Slat, Jasmin Sponagel, Luciano Marpegán, Tatiana Simon, Najla Kfoury, Albert Kim, Andrea Binz, Erik D. Herzog, Joshua B. Rubin · 2017 · Journal of Biological Rhythms
Solid Lipid Nanoparticles and Nanostructured Lipid Carriers as Smart Drug Delivery Systems in the Treatment of Glioblastoma Multiforme
Raneem Jnaidi, António José Almeida, Lídia Gonçalves · 2020 · Pharmaceutics
Mechanisms of Cell Cycle Arrest and Apoptosis in Glioblastoma
Konstantinos Gousias, Theocharis Theocharous, Matthias Simon · 2022 · Biomedicines
New Directions in the Therapy of Glioblastoma
Katarzyna Szklener, Marek Mazurek, Małgorzata Wieteska, Monika Wacławska, Mateusz Bilski, Sławomir Mańdziuk · 2022 · Cancers
Hypoxia within the glioblastoma tumor microenvironment: a master saboteur of novel treatments
Lisa A. Feldman · 2024 · Frontiers in Immunology
CONSERTING: integrating copy-number analysis with structural-variation detection
Xiang 'Anthony' Chen, Pankaj Gupta, Jianmin Wang, Joy Nakitandwe, Kathryn G. Roberts, James Dalton, Matthew D. Parker, SAMIR N. PATEL, Linda Holmfeldt, Debbie Payne et al. · 2015 · Nature Methods
InsR/IGF1R Pathway Mediates Resistance to EGFR Inhibitors in Glioblastoma
Yufang Ma, Nan Tang, Reid C. Thompson, Bret C. Mobley, Steven W. Clark, Jann Nagina Sarkaria, Jialiang Wang · 2015 · Clinical Cancer Research
Long non-coding RNAs as novel therapeutic targets in cancer
Giovanni Lavorgna, Riccardo Vago, Mohamad Sarmini, Francesco Montorsi, Andrea Salonia, Matteo Bellone · 2016 · Pharmacological Research
Mechanisms of EGFR Resistance in Glioblastoma
Peter Pan, Rajiv Magge · 2020 · International Journal of Molecular Sciences
Clinical measures, radiomics, and genomics offer synergistic value in AI-based prediction of overall survival in patients with glioblastoma
Anahita Fathi Kazerooni, Sanjay Saxena, Erik Toorens, Danni Tu, Vishnu Bashyam, Hamed Akbari, Elizabeth Mamourian, Chiharu Sako, Constantinos Koumenis, Ioannis I. Verginadis et al. · 2022 · Scientific Reports
Highly Accurate Estimation of Cell Type Abundance in Bulk Tissues Based on Single‐Cell Reference and Domain Adaptive Matching
Xinyang Guo, Zhaoyang Huang, Fen Ju, Chenguang Zhao, Liang Yu · 2023 · Advanced Science
Phase 0 Trial of AZD1775 in First-Recurrence Glioblastoma Patients
Nader Sanai, Jing Li, Julie L. Boerner, Karri Stark, Jianmei Wu, Seongho Kim, Alanna Derogatis, Shwetal V. Mehta, Harshil Dhruv, Lance K. Heilbrun et al. · 2018 · Clinical Cancer Research
Comprehensive analysis of microRNA expression profile in malignant glioma tissues
Piwecka, Monika, Rolle, Katarzyna, Belter, Agnieszka, Barciszewska, Anna Maria, Żywicki, Marek, Michalak, Marcin, Nowak, Stanisław, Naskręt-Barciszewska, Mirosława Z., Barciszewski, Jan · 2015 · Molecular Oncology
Modeling Mutual Exclusivity of Cancer Mutations
Ewa Szczurek, Niko Beerenwinkel · 2014 · PLoS Computational Biology
HPAanalyze: an R package that facilitates the retrieval and analysis of the Human Protein Atlas data
Anh Nhat Tran, Alex Dussaq, Timothy Kennell, Christopher Douglas Willey, Anita B. Hjelmeland · 2019 · BMC Bioinformatics
PDGF signaling inhibits mitophagy in glioblastoma stem cells through N-methyladenosine
Deguan Lv, Ryan C. Gimple, Cuiqing Zhong, Qiulian Wu, Kailin Yang, Briana C. Prager, Bhaskar Godugu, Zhixin Qiu, Linjie Zhao, Guoxin Zhang et al. · 2022 · Developmental Cell
Delivering the Promise of Gene Therapy with Nanomedicines in Treating Central Nervous System Diseases
Meihua Luo, Leo Kit Cheung Lee, Bo Peng, Chung Hang Jonathan Choi, Wing Yin Tong, Nicolas Hans Voelcker · 2022 · Advanced Science
DNA Methylation: From Cancer Biology to Clinical Perspectives
Chen Chen, Zehua Wang, Yi Ding, Lei Wang, Siyuan Wang, Haonan Wang, Yanru Qin · 2022 · Frontiers in Bioscience-Landmark
Telomere maintenance and the etiology of adult glioma
Kyle M. Walsh, John K. Wiencke, Daniel Honore Lachance, Joseph Leo Wiemels, Annette M Molinaro, Jeanette E. Eckel‐Passow, Robert Brian Jenkins, Margaret Wrensch · 2015 · Neuro-Oncology
Beating the odds: extreme long-term survival with glioblastoma
Wenya Linda Bi, Rameen Beroukhim · 2014 · Neuro-Oncology
Expression site of P2RY12 in residential microglial cells in astrocytomas correlates with M1 and M2 marker expression and tumor grade
Zhu, Changbin, Kros, Johan M., van der Weiden, Marcel, Zheng, PingPin, Cheng, Caroline, Mustafa, Dana A. M. · 2017 · Acta Neuropathologica Communications
The potential of cerebrospinal fluid-based liquid biopsy approaches in CNS tumors.
A. Mattox, Hai Yan, C. Bettegowda · 2019 · Neuro-Oncology
The Intratumoral Heterogeneity Reflects the Intertumoral Subtypes of Glioblastoma Multiforme: A Regional Immunohistochemistry Analysis
Natalie Bergmann, Claire Delbridge, Jens Gempt, Annette Feuchtinger, Axel Karl Walch, Lucas Schirmer, Wolfram Bunk, Thomas Aschenbrenner, Friederike Liesche‐Starnecker, Jürgen Schlegel · 2020 · Frontiers in Oncology