The Somatic Genomic Landscape of Glioblastoma

Brennan, Cameron W., Verhaak, Roel G.W., McKenna, Aaron, Campos, Benito, Noushmehr, Houtan, Salama, Sofie R., Zheng, Siyuan, Chakravarty, Debyani +292 more·2013·Cell

DOI 10.1016/j.cell.2013.09.034

Cited by (1,018)

Items 301–400 of 1,018

Glioma Biology and Molecular Markers
Adam Louis Cohen, Howard Colman · 2014 · Cancer treatment and research
B7-H3-redirected chimeric antigen receptor T cells target glioblastoma and neurospheres
Dean Nehama, Natalia Di Ianni, Silvia Musio, Hongwei Du, Monica Patanè, Bianca Pollo, Gaetano Finocchiaro, James J.H. Park, Denise Dunn, Drake S. Edwards et al. · 2019 · EBioMedicine
Immunotherapy for Glioblastoma: Current Progress and Challenges
Miranda W. Yu, Daniela F. Quail · 2021 · Frontiers in Immunology
Hallmarks of glioblastoma: a systematic review
Dorte Schou Nørøxe, Hans Skovgaard Poulsen, Ulrik Lassen · 2016 · ESMO Open
Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium
Kenneth Aldape, Samirkumar B. Amin, David M. Ashley, Jill S. Barnholtz‐Sloan, Amanda J Bates, Rameen Beroukhim, Christoph Bock, Daniel Jay Brat, Elizabeth B. Claus, J Costello et al. · 2018 · Neuro-Oncology
Circulating biomarkers for gliomas
Manfred Westphal, Katrin Lamszus · 2015 · Nature Reviews Neurology
Molecular Diagnostics of Gliomas Using Next Generation Sequencing of a Glioma‐Tailored Gene Panel
Angela Zacher, Kerstin Kaulich, Stefanie Stepanow, Marietta Wolter, Karl Köhrer, Jörg Felsberg, Bastian Malzkorn, Guido Reifenberger · 2016 · Brain Pathology
An Electrochemical Biosensor Designed by Using Zr-Based Metal–Organic Frameworks for the Detection of Glioblastoma-Derived Exosomes with Practical Application
Zhaowei Sun, Lei Wang, Shuai Wu, Yanhong Pan, Yu Dong, Sha Zhu, Jie An Yang, Yongmei Yin, Genxi Li · 2020 · Analytical Chemistry
Metabolic therapy: A new paradigm for managing malignant brain cancer
Thomas N. Seyfried, Roberto E. Flores, Angela M. Poff, Dominic P. D’Agostino, Purna Mukherjee · 2014 · Cancer Letters
PD-L1/PD-1 Axis in Glioblastoma Multiforme
Jakub Litak, Marek Mazurek, Cezary Grochowski, Piotr Kamieniak, Jacek Roliński · 2019 · International Journal of Molecular Sciences
Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas
Martin J. van den Bent, Ya Gao, Melissa Kerkhof, Johan M. Kros, Thierry Gorlia, Kitty van Zwieten, Jory Prince, Sjoerd G. van Duinen, Peter A.E. Sillevis Smitt, MARTIN J.B. TAPHOORN et al. · 2015 · Neuro-Oncology
Hypoxia: The Cornerstone of Glioblastoma
Marta Doménech, Ainhoa Hernández, Andrea Plaja, Eva Martinez‐Balibrea, Carmen Balañá · 2021 · International Journal of Molecular Sciences
Glioblastoma heterogeneity at single cell resolution
David Eisenbarth, Yanru Wang · 2023 · Oncogene
Pan-cancer patterns of DNA methylation
Tania Witte, Christoph Plass, Clarissa Gerhäuser · 2014 · Genome Medicine
A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence
Camila Ferreira de Souza, Thaís S. Sabedot, Tathiane Maistro Malta, Lindsay C. Stetson, Olena Morozova, Artem Sokolov, Peter W. Laird, Maciej Wiznerowicz, Antonio Iavarone, James Snyder et al. · 2018 · Cell Reports
The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma
Bill H. Diplas, Xujun He, Jacqueline A. Brosnan‐Cashman, Heng Liu, Lee H. Chen, Zhaohui Wang, Casey J. Moure, Patrick J. Killela, Daniel B. Loriaux, Eric Lipp et al. · 2018 · Nature Communications
IGFBP2: integrative hub of developmental and oncogenic signaling network
Tao Li, M. Elizabeth Forbes, Gregory N. Fuller, Jiabo Li, Xuejun Yang, Wei Zhang · 2020 · Oncogene
EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXM1-Dependent Manner
Sung-Hak Kim, Kaushal Joshi, Ravesanker Ezhilarasan, Toshia R. Myers, Jason J. Siu, Chunyu Gu, Mariko Nakano‐Okuno, David Taylor, Mutsuko Minata, Erik P. Sulman et al. · 2015 · Stem Cell Reports
Epidermal growth factor receptor in glioblastoma
Hongsheng Xu, Hailiang Zong, Chong Ma, Xing Ming, Ming Shang, Kai Li, Xiaoguang He, Hai Du, Lei Cao · 2017 · Oncology Letters
Glioblastoma Clinical Trials: Current Landscape and Opportunities for Improvement
Stephen Joseph Bagley, Shawn Kothari, Rifaquat M. Rahman, Eudocia Q. Lee, Gavin P. Dunn, Evanthia Galanis, Susan Marina Chang, Burt Nabors, Manmeet Singh Ahluwalia, Roger Stupp et al. · 2021 · Clinical Cancer Research
The Impact of Oncogenic EGFRvIII on the Proteome of Extracellular Vesicles Released from Glioblastoma Cells
Dongsic Choi, Laura Montermini, Dae‐Kyum Kim, Brian Meehan, Frederick P. Roth, Janusz W. Rak · 2018 · Molecular & Cellular Proteomics
Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial
Patrick Yung Wen, Mehdi Touat, Brian Michael Alexander, Ingo K. Mellinghoff, Shakti H Ramkissoon, Christine Sceppa McCluskey, Kristine Pelton, Sam Haidar, Sankha S. Basu, Sarah C. Gaffey et al. · 2019 · Journal of Clinical Oncology
Analysis of cell-free circulating tumor DNA in 419 patients with glioblastoma and other primary brain tumors
David Eric Piccioni, Achal Singh Achrol, Lesli Ann Kiedrowski, Kimberly C. Banks, Najee Boucher, Garni Barkhoudarian, Daniel F. Kelly, Tiffany Juarez, Richard Burnham Lanman, Victoria M. Raymond et al. · 2019 · CNS Oncology
Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas
Allison R. Pine, Stéfano M. Cirigliano, James Nicholson, Yang Hu, Amanda G. Linkous, Ken Miyaguchi, Lincoln Edwards, Richa Singhania, Theodore H. Schwartz, Rohan R. Ramakrishna et al. · 2020 · Cancer Discovery
Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma
Wei Wei, Young Shik Shin, Min Xue, Tomoo Matsutani, Kenta Masui, Huijun Yang, Shiro Ikegami, Yuchao Gu, Ken Herrmann, Dazy Johnson et al. · 2016 · Cancer Cell
Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma
Erika C. Cosset, Sten Ilmjärv, Valérie Dutoit, Kathryn C. Elliott, Tami Von Schalscha, Maria F. Camargo, Alexander Reiss, Toshiro Moroishi, Laetitia Seguin, German G. Gomez et al. · 2017 · Cancer Cell
Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development
Zev A. Binder, Amy Haseley Thorne, Spyridon Bakas, E. Paul Wileyto, Michel Bilello, Hamed Akbari, Saima Rathore, Sung Min Ha, Logan Zhang, Cole Ferguson et al. · 2018 · Cancer Cell
A phase 2 study of the first imipridone ONC201, a selective DRD2 antagonist for oncology, administered every three weeks in recurrent glioblastoma
Isabel Arrillaga‐Romany, Andrew S. Chi, Joshua E. Allen, Wolfgang Oster, Patrick Yung Wen, Tracy T. Batchelor · 2017 · Oncotarget
Emerging Therapies for Glioblastoma
Alissa A. Thomas, Cameron Brennan, Lisa Marie DeAngelis, Antonio M. P. Omuro · 2014 · JAMA Neurology
Sox2 Promotes Malignancy in Glioblastoma by Regulating Plasticity and Astrocytic Differentiation
Artem D. Berezovsky, Laila Poisson, David Cherba, Craig Paul Webb, Andrea D. Transou, Nancy W. Lemke, Xin Hong, Laura A. Hasselbach, Susan M. Irtenkauf, Tom Mikkelsen et al. · 2014 · Neoplasia
Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis
Qi Cui, Kailin Yin, Xiaoting Zhang, Peng Ye, Xianwei Chen, Jianfei Chao, Haowei Meng, Jiangbo Wei, Daniel Roeth, Li Li et al. · 2021 · Nature Cancer
Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2
Guozhong Yi, Guanglong Huang, Manlan Guo, Xian Zhang, Hai Wang, Shengze Deng, Yaomin Li, Wei Xiang, Ziyang Chen, Jun Pan et al. · 2019 · Brain
Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in glioblastoma
Martina Castellan, Alberto Guarnieri, Atsushi Fujimura, Francesca Zanconato, Giusy Battilana, Tito Panciera, Hanna Lucie Sladitschek, Paolo Contessotto, Anna Citron, Andrea Grilli et al. · 2020 · Nature Cancer
The CRISPR‐Cas13a Gene‐Editing System Induces Collateral Cleavage of RNA in Glioma Cells
Qixue Wang, Xing Liu, Junhu Zhou, Chao Yang, Guangxiu Wang, Yanli Tan, Ye Wu, Sijing Zhang, Kaikai Yi, Chunsheng Kang · 2019 · Advanced Science
DNA Hypomethylating Drugs in Cancer Therapy
Takahiro Sato, Jean‐Pierre J. Issa, Patricia Lamont Kropf · 2017 · Cold Spring Harbor Perspectives in Medicine
The cancer COMPASS: navigating the functions of MLL complexes in cancer
David J. Ford, Andrew K. Dingwall · 2015 · Cancer Genetics
Pitfalls in the Neuroimaging of Glioblastoma in the Era of Antiangiogenic and Immuno/Targeted Therapy – Detecting Illusive Disease, Defining Response
Raymond Y. Huang, Martha R. Neagu, David A. Reardon, Patrick Yung Wen · 2015 · Frontiers in Neurology
Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082)
Wolfgang Wick, Thierry Gorlia, Pierre Bady, Michael Platten, Martin J. van den Bent, MARTIN J.B. TAPHOORN, Jonathan Steuve, Alba Ariela Brandes, Marie‐France Hamou, Antje Wick et al. · 2016 · Clinical Cancer Research
Cell of origin of glioma: biological and clinical implications
Sheila R. Alcantara Llaguno, Luis F. Parada · 2016 · British Journal of Cancer
Vaccine-based immunotherapeutic approaches to gliomas and beyond
Michael Weller, Patrick Roth, Matthias Preusser, Wolfgang Wick, David A. Reardon, Michael Platten, John Howard Sampson · 2017 · Nature Reviews Neurology
Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
Weiwei Tao, Cheng‐Wei Chu, Wenchao Zhou, Zhi Huang, Kui Zhai, Xiaoguang Fang, Qian Huang, Aili Zhang, Xiuxing Wang, Xingjiang Yu et al. · 2020 · Nature Communications
Current Opinion on Molecular Characterization for GBM Classification in Guiding Clinical Diagnosis, Prognosis, and Therapy
Pei Zhang, Xia Qin, Liqun Liu, Shouwei Li, Lei Dong · 2020 · Frontiers in Molecular Biosciences
Targeting MTHFD2 in acute myeloid leukemia
Yana Pikman, Alexandre Puissant, Gabriela Alexe, Andrew A. Furman, Liying M. Chen, Stacey M. Frumm, Linda S. Ross, Nina Fenouille, Christopher F. Bassil, Caroline A. Lewis et al. · 2016 · The Journal of Experimental Medicine
Updated Insights on EGFR Signaling Pathways in Glioma
Alexandru Oprița, Carina Baloi, Georgiana-Adeline Staicu, Oana Alexandru, Daniela Elise Tache, Suzana Dănoiu, Elena Simona Micu, Ani-Simona Sevastre · 2021 · International Journal of Molecular Sciences
Single-Cell Landscapes of Primary Glioblastomas and Matched Organoids and Cell Lines Reveal Variable Retention of Inter- and Intra-Tumor Heterogeneity
Véronique Leblanc, Diane L.N. Trinh, Shaghayegh Aslanpour, Martha L. Hughes, Dorothea Livingstone, Dan Jin, Bo Young Ahn, Michael D. Blough, John Gregory Cairncross, Jennifer Ai-wen Chan et al. · 2021 · Cancer Cell
Myc-Driven glycolysis is a therapeutic target in glioblastoma
Tateishi, Kensuke, Iafrate, A. John, Ho, Quan, Curry, William T., Batchelor, Tracy T., Flaherty, Keith T., Onozato, Maristela L., Lelic, Nina, Sundaram, Sudhandra, Cahill, Daniel P. et al. · 2016 · Clinical Cancer Research
Mutant ATRX: uncovering a new therapeutic target for glioma
Santiago Haase, María Belén Garcia-Fabiani, Stephen V. Carney, David B. Altshuler, Felipe Javier Núñez, Flor Mendez, Fernando M. Núñez, Pedro Ricardo Lowenstein, Maria Graciela Castro · 2018 · Expert Opinion on Therapeutic Targets
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology
Anna Golebiewska, Ann‐Christin Hau, Anaïs Oudin, Daniel Stieber, Yahaya Abubakar Yabo, Virginie Baus, Vanessa Barthelemy, Eliane Klein, Sébastien Bougnaud, Olivier Keunen et al. · 2020 · Acta Neuropathologica
Erlotinib and the Risk of Oral Cancer
William N. William, Vassiliki A. Papadimitrakopoulou, J. Jack Lee, Li Mao, Ezra E.W. Cohen, Heather Yan Lin, Ann Marie Gillenwater, Jack W. Martin, Mark William Lingen, Jay O. Boyle et al. · 2015 · JAMA Oncology
Classification of adult‐type diffuse gliomas: Impact of the World Health Organization 2021 update
Benjamin T. Whitfield, Jason T. Huse · 2022 · Brain Pathology
Combining dependent P- values with an empirical adaptation of Brown’s method
William Poole, David L. Gibbs, Ilya Shmulevich C, Brady M. Bernard, Theo Knijnenburg · 2016 · Bioinformatics
Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity
Daniel V. Brown, Gulay Filiz, Paul M Daniel, Frédéric Hollande, Sebastian Dworkin, Stephanie Amiridis, Nicole Kountouri, Wayne Ng, Andrew P. Morokoff, Theo Mantamadiotis · 2017 · PLoS ONE
Use of a molecular classifier to identify usual interstitial pneumonia in conventional transbronchial lung biopsy samples: a prospective validation study
Ganesh Raghu, Kevin R. Flaherty, David J. Lederer, David A. Lynch, Thomas Vail Colby, Jeffrey L. Myers, Steve D. Groshong, Brandon T. Larsen, Jonathan Hero Chung, Mark P. Steele et al. · 2019 · The Lancet Respiratory Medicine
Histone H3.3K27M Represses <i>p16</i> to Accelerate Gliomagenesis in a Murine Model of DIPG
Cordero, Francisco J., Huang, Zhiqing, Grenier, Carole, He, Xingyao, Hu, Guo, McLendon, Roger E., Murphy, Susan K., Hashizume, Rintaro, Becher, Oren J. · 2017 · Molecular Cancer Research
Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas
Philip Jonsson, Andrew L. Lin, Robert J. Young, Natalie M. DiStefano, David Michael Hyman, Bob T. Li, Michael F. Berger, Ahmet Zehir, Marc Ladanyi, David B. Solit et al. · 2019 · Clinical Cancer Research
Recurrent Glioblastoma: A Review of the Treatment Options
María Ángeles Vaz Salgado, María Luisa Villamayor, Víctor Albarrán, Víctor Alía, Pilar Sotoca, Jesús Chamorro, Diana Isabel Rosero, Ana María Barrill, Mercedes Martín, Eva Fernández et al. · 2023 · Cancers
An integrated transcriptomic cell atlas of human neural organoids
Zhisong He, Leander Dony, Jonas Simon Fleck, Artur Szałata, Katelyn X. Li, Irena Slišković, Hsiu‐Chuan Lin, Małgorzata Santel, Alexander Atamian, Giorgia Quadrato et al. · 2024 · Nature
Clinical, Immunological, and Genetic Features in Patients with Activated PI3Kδ Syndrome (APDS): a Systematic Review
Mahnaz Jamee, Shakiba Moniri, Majid Zaki‐Dizaji, Peter Olbrich, Reza Yazdani, Farhad Jadidi‐Niaragh, Fatemeh Aghamahdi, Hassan Abolhassani, Alison Mary Condliffe, Asghar Aghamohammadi et al. · 2019 · Clinical Reviews in Allergy & Immunology
CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data
Akdes Serin Harmancı, Arif O. Harmanci, Xiaobo Zhou · 2020 · Nature Communications
Glioma-Derived miRNA-Containing Extracellular Vesicles Induce Angiogenesis by Reprogramming Brain Endothelial Cells
Rocco Lucero, Valentina Zappulli, Alessandro Sammarco, Oscar D. Murillo, Pike-See Cheah, Srimeenakshi Srinivasan, Eric C. Tai, David Tsai Ting, Zhiyun Wei, Matthew E. Roth et al. · 2020 · Cell Reports
Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways
Xiangqi Meng, Yu Zhao, Bo Ram Han, Caijun Zha, Yangong Zhang, Ziwei Li, Pengfei Wu, Tengfei Qi, Chuanlu Jiang, Yang Liu et al. · 2020 · Nature Communications
Translation of noncoding RNAs and cancer
Bo Zhou, Huan Yang, Chuan He Yang, Yulu Bao, Shiming Yang, Jiao Liu, Yufeng Xiao · 2020 · Cancer Letters
Temozolomide Induced Hypermutation in Glioma: Evolutionary Mechanisms and Therapeutic Opportunities
Paul M Daniel, Siham Sabri, Ahmad Chaddad, Brian Meehan, Bertrand J. Jean‐Claude, Janusz W. Rak, Bassam Abdulkarim · 2019 · Frontiers in Oncology
Metabolic Abnormalities in Glioblastoma and Metabolic Strategies to Overcome Treatment Resistance
Weihua Zhou, Daniel Richard Wahl · 2019 · Cancers
Spatial cellular architecture predicts prognosis in glioblastoma
Yuanning Zheng, Francisco Carrillo‐Pérez, Marija Pizurica, Dieter Henrik Heiland, Olivier Gevaert · 2023 · Nature Communications
Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene
Muhammad Khairul Ramlee, Jing Wang, Wei Hong Toh, Shang Li · 2016 · Genes
A clinical perspective on the 2016 WHO brain tumor classification and routine molecular diagnostics
Martin J. van den Bent, Michael Weller, Patrick Yung Wen, Johan M. Kros, Ken D. Aldape, Susan Marina Chang · 2017 · Neuro-Oncology
Pro-inflammatory and proliferative microglia drive progression of glioblastoma
Hailong Liu, Youliang Sun, Qian Zhang, Wei Jin, Renata E. Gordon, Yanyang Zhang, Jian Wang, Caihong Sun, Zeyuan Wang, Xueling Qi et al. · 2021 · Cell Reports
Emerging Insights into Barriers to Effective Brain Tumor Therapeutics
Graeme F. Woodworth, Gavin P. Dunn, Elizabeth A. Nance, Justin S. Hanes, Henry Brem · 2014 · Frontiers in Oncology
mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance
Laura Garros-Regulez, Paula Aldaz, Olatz Arrizabalaga, Verónica Moncho-Amor, Estefanía Carrasco‐García, Lorea Manterola, Leire Moreno‐Cugnon, Cristina Barrena, Jorge Villanúa, Irune Ruiz et al. · 2016 · Expert Opinion on Therapeutic Targets
The genetic landscape of anaplastic pleomorphic xanthoastrocytoma
Joanna J. Phillips, Henry Z. Gong, Katharine Y. Chen, Nancy M. Joseph, Jessica Van Ziffle, Boris C. Bastian, James P. Grenert, Cassie Kline, Sabine Mueller, Anuradha Banerjee et al. · 2018 · Brain Pathology
Bioinformatics Approaches for Anti-cancer Drug Discovery
Kening Li, Yuxin Du, Lu Li, Dong‐Qing Wei · 2019 · Current Drug Targets
Imaging of intratumoral heterogeneity in high-grade glioma
Leland Hu, Andrea J. Hawkins-Daarud, Lujia Wang, Jing Li, Kristin R. Swanson · 2020 · Cancer Letters
Effects of aneuploidy on cell behaviour and function
Rong Li, Jin Zhu · 2022 · Nature Reviews Molecular Cell Biology
<i>EGFR</i> Fusions as Novel Therapeutic Targets in Lung Cancer
Konduri, Kartik, Gallant, Jean-Nicolas, Chae, Young Kwang, Giles, Francis J., Gitlitz, Barbara J., Gowen, Kyle, Ichihara, Eiki, Owonikoko, Taofeek K., Peddareddigari, Vijay, Ramalingam, Suresh S. et al. · 2016 · Cancer Discovery
Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling
Guido Reifenberger, Ruthild G. Weber, Vera Riehmer, Kerstin Kaulich, Edith Willscher, Henry Loeffler‐Wirth, Jens Gietzelt, Bettina Hentschel, Manfred Westphal, Matthias Simon et al. · 2014 · International Journal of Cancer
Sensitivity Analysis of the MGMT-STP27 Model and Impact of Genetic and Epigenetic Context to Predict the MGMT Methylation Status in Gliomas and Other Tumors
Pierre Bady, Mauro Delorenzi, Monika E. Hegi · 2016 · Journal of Molecular Diagnostics
2016 World Health Organization Classification of Central Nervous System Tumors
Patrick Yung Wen, Jason T. Huse · 2017 · CONTINUUM Lifelong Learning in Neurology
Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma
Bryan G. Harder, Mylan R Blomquist, Junwen Wang, Anthony J. Kim, Graeme F. Woodworth, Jeffrey A. Winkles, Joseph C. Loftus, Nhan L. Tran · 2018 · Frontiers in Oncology
DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureas
Bernd Kaina, Markus Christmann · 2019 · DNA repair
Collateral lethality: a new therapeutic strategy in oncology
Muller, Florian L., Aquilanti, Elisa A., DePinho, Ronald A. · 2015 · Trends in Cancer
A glial blueprint for gliomagenesis
Dylan Laug, Stacey M. Glasgow, Benjamin Deneen · 2018 · Nature reviews. Neuroscience
TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma
Sabine Spiegl‐Kreinecker, Daniela Lötsch, Katharina Neumayer, Lucia Kastler, Johannes Gojo, Christine Pirker, Josef Pichler, Serge Weis, Rajiv Kumar, Gerald Webersinke et al. · 2018 · Neuro-Oncology
N2M2 (NOA-20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma
Wolfgang Wick, Susan Dettmer, Anne Berberich, Tobias Keßler, Irini Karapanagiotou‐Schenkel, Antje Wick, Frank Winkler, Elke Pfaff, Benedikt Brors, Jürgen Debus et al. · 2018 · Neuro-Oncology
The prognostic significance of CDKN2A homozygous deletion in IDH-mutant lower-grade glioma and glioblastoma: a systematic review of the contemporary literature
Victor M. Lu, Kyle P. O’Connor, Ashish Harish Shah, Daniel G. Eichberg, Evan Luther, Ricardo J. Komotar, Michael E. Ivan · 2020 · Journal of Neuro-Oncology
Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing
Svenja Kristin Tetzlaff, Ekin Reyhan, Nikolas Layer, C. Peter Bengtson, Alina Heuer, Julian Schroers, Anton J Faymonville, Atefeh Pourkhalili Langeroudi, Nina Drewa, Elijah Keifert et al. · 2024 · Cell
CNS macrophages and peripheral myeloid cells in brain tumours
Rainer Glaß, Michael Synowitz · 2014 · Acta Neuropathologica
PINK1 Is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma
Sameer Agnihotri, Brian J. Golbourn, Xi Huang, Marc Remke, Susan H. Younger, Rob A. Cairns, Alan Chalil, Christian A. Smith, Stacey-Lynn Krumholtz, Danielle Mackenzie et al. · 2016 · Cancer Research
Sensitization of glioblastoma tumor micro-environment to chemo- and immunotherapy by Galectin-1 intranasal knock-down strategy
Matthias Van Woensel, Thomas Mathivet, Nathalie Wauthoz, Rémi Rosière, Abhishek Dinkarnath Garg, Patrizia Agostinis, Véronique Mathieu, Robert Kiss A, Florence Lefranc, Louis Boon et al. · 2017 · Scientific Reports
Targeting autophagy for combating chemoresistance and radioresistance in glioblastoma
Matthew A. Taylor, Bhaskar C. Das, Swapan K. Ray · 2018 · APOPTOSIS
Context-Dependent Glioblastoma–Macrophage/Microglia Symbiosis and Associated Mechanisms
Wenjing Xuan, Maciej S. Lesniak, Charles David James, Amy B. Heimberger, Peiwen Chen · 2021 · Trends in Immunology
Therapeutic Potential of Targeting the Oncogenic SHP2 Phosphatase
Li‐Fan Zeng, Ruoyu Zhang, Zhi-Hong Yu, Sijiu Li, Li Wu, Andrea Michelle Gunawan, Brandon S. Lane, Raghuveer Singh Mali, Xingjun Li, Rebecca J. Chan et al. · 2014 · Journal of Medicinal Chemistry
Molecular markers for colorectal cancer screening
Brandon Dickinson, John B. Kisiel, David A. Ahlquist, William M. Grady · 2015 · Gut
Immune checkpoint blockade as a potential therapeutic target: surveying CNS malignancies
Sarah T. Garber, Yuuri Hashimoto, Shiao-Pei S. Weathers, Joanne Xiu, Zoran Gatalica, Roel G.W. Verhaak, Shouhao Zhou, Gregory N. Fuller, Mustafa Khasraw, John de Groot et al. · 2016 · Neuro-Oncology
A Comparison of RNA-Seq Results from Paired Formalin-Fixed Paraffin-Embedded and Fresh-Frozen Glioblastoma Tissue Samples
Anna Esteve‐Codina, Oriol Arpí, Maria Martinez‐García, Estela Pineda, Mar Mallo, Marta Gut, Cristina Carrato, Ana Rovira, Raquel Lopez, Avelina Tortosa et al. · 2017 · PLoS ONE
Efficacy of depatuxizumab mafodotin (ABT-414) monotherapy in patients with EGFR-amplified, recurrent glioblastoma: results from a multi-center, international study
Martin J. van den Bent, Hui Kong Gan, Andrew B. Lassman, Priya Kumthekar, Ryan Thomas Merrell, Nicholas Arthur Butowski, Zarnie Lwin, Tom Mikkelsen, Burt Nabors, Kyriakos P. Papadopoulos et al. · 2017 · Cancer Chemotherapy and Pharmacology
Targeting RTK-PI3K-mTOR Axis in Gliomas: An Update
Mayra Colardo, Marco Segatto, Sabrina Di Bartolomeo · 2021 · International Journal of Molecular Sciences
β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages
Daqi Li, Qian Zhang, Lu Li, Kexin Chen, Junlei Yang, Deobrat Dixit, Ryan C. Gimple, Shusheng Ci, Chenfei Lu, Lang Hu et al. · 2022 · Cancer Research
Impact of outdated gene annotations on pathway enrichment analysis
Lina Wadi, Mona Meyer, Joel Weiser, Lincoln David Stein, Jüri Reimand · 2016 · Nature Methods
High-Throughput Genomic Profiling of Adult Solid Tumors Reveals Novel Insights into Cancer Pathogenesis
Ryan James Hartmaier, Lee A. Albacker, Juliann Chmielecki, Mark Bailey, Jie He, Michael E. Goldberg, Shakti H Ramkissoon, James H. Suh, Julia Andrea Elvin, Sam Chiacchia et al. · 2017 · Cancer Research