The Somatic Genomic Landscape of Glioblastoma
Brennan, Cameron W., Verhaak, Roel G.W., McKenna, Aaron, Campos, Benito, Noushmehr, Houtan, Salama, Sofie R., Zheng, Siyuan, Chakravarty, Debyani +292 more·2013·Cell
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Items 101–200 of 1,018
- Challenges and Opportunities in Cancer Drug ResistanceRichard A. Ward, Stephen E. Fawell, Nicolas Floc’h, Vikki Flemington, Darren McKerrecher, Paul D. Smith · 2020 · Chemical Reviews
- Brain malignancies: Glioblastoma and brain metastasesTamara T. Lah, Metka Novak, Barbara Breznik · 2019 · Seminars in Cancer Biology
- Glioblastoma targeted therapy: updated approaches from recent biological insightsMehdi Touat, Ahmed Idbaïh, Marc Sanson, Keith Lloyd Ligon · 2017 · Annals of Oncology
- Immune Microenvironment in Glioblastoma SubtypesZhihong Chen, Dolores Hambardzumyan · 2018 · Frontiers in Immunology
- Trivalent CAR T cells overcome interpatient antigenic variability in glioblastomaKevin Bielamowicz, Kristen Fousek, Tiara T. Byrd, Heba Samaha, Malini Mukherjee, Nikita Aware, Meng-Fen Wu, Jordan Scott Orange, Pavel Sumazin, Tsz‐Kwong Man et al. · 2017 · Neuro-Oncology
- Primary brain tumours in adultsMartin J. van den Bent, Marjolein Geurts, Pim J. French, Marion Smits, David Capper, Jacoline E. C. Bromberg, Susan Marina Chang · 2023 · The Lancet
- Macrophages and microglia in glioblastoma: heterogeneity, plasticity, and therapyFatima Khan, Lizhi Pang, Madeline Dunterman, Maciej S. Lesniak, Amy B. Heimberger, Peiwen Chen · 2023 · Journal of Clinical Investigation
- Genetically engineered cerebral organoids model brain tumor formationShan Bian, Marko Repic, Zhenming Guo, Anoop Murthy Kavirayani, Thomas Rainer Burkard, Joshua A. Bagley, Christian Krauditsch, Juergen A. Knoblich · 2018 · Nature Methods
- Mitochondrial control by DRP1 in brain tumor initiating cellsQi Xie, Qiulian Wu, Craig Horbinski, William A. Flavahan, Kailin Yang, Wenchao Zhou, Stephen M. Dombrowski, Zhi Huang, Xiaoguang Fang, Yu Shi et al. · 2015 · Nature Neuroscience
- The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem CellsDeobrat Dixit, Briana C. Prager, Ryan C. Gimple, Hui Xian Poh, Yang Wang, Qiulian Wu, Zhixin Qiu, Reilly L. Kidwell, Leo J.Y. Kim, Qi Xie et al. · 2020 · Cancer Discovery
- Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolutionKim, Hoon, Zheng, Siyuan, Amini, Seyed S., Virk, Selene M., Mikkelsen, Tom, Brat, Daniel J., Grimsby, Jonna, Sougnez, Carrie, Muller, Florian, Hu, Jian et al. · 2015 · Genome Research
- Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastomaMaleeha A. Qazi, Parvez Vora, Chitra Venugopal, Sachdev S. Sidhu, Jason Moffat, Charles Swanton, Sheila Kumari Singh · 2017 · Annals of Oncology
- Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1Frank Szulzewsky, Andreas Pelz, Xi Feng, Michael Synowitz, Darko S. Markovic, Thomas Langmann, Inge R. Holtman, Xi Wang, Bart J. L. Eggen, H. W. G. M. Boddeke et al. · 2015 · PLoS ONE
- Fate mapping of human glioblastoma reveals an invariant stem cell hierarchyXiaoyang Lan, David J. Jörg, Florence M.G. Cavalli, Laura M. Richards, Long V. Nguyen, Robert J. Vanner, Paul Guilhamon, Lilian Lee, Michelle M. Kushida, Davide Pellacani et al. · 2017 · Nature
- Mechanisms of PTEN loss in cancer: It’s all about diversityVirginia Alvarez Garcia, Yasmine Tawil, Helen M. Wise, Nicholas R. Leslie · 2019 · Seminars in Cancer Biology
- Mutant IDH1 regulates the tumor-associated immune system in gliomasNduka Amankulor, Youngmi Kim, Sonali Arora, Julia Kargl, Frank Szulzewsky, Mark L. Hanke, Daciana H. Margineantu, Aparna Rao, Hamid Bolouri, Jeff J. Delrow et al. · 2017 · Genes & Development
- Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphologyIbrahim A. Qaddoumi, Wilda Orisme, Ji Wen, Teresa Santiago, Kirti Gupta, James Dalton, Bo Tang, Kelly Haupfear, Chandanamali Punchihewa, John B. Easton et al. · 2016 · Acta Neuropathologica
- Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescenceGabriele Sulli, Amy Rommel, Xiaojie Wang, Matthew J. Kolar, Francesca Puca, Alan Saghatelian, Maksim V. Plikus, Inder M. Verma, Satchidananda Panda · 2018 · Nature
- Federated learning enables big data for rare cancer boundary detectionPati, Sarthak, Baid, Ujjwal, Edwards, Brandon, Sheller, Micah, Wang, Shih-Han, Reina, G. Anthony, Foley, Patrick, Gruzdev, Alexey, Karkada, Deepthi, Davatzikos, Christos et al. · 2022 · Nature Communications
- Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy numberLyons, Jonathan J, Yu, Xiaomin, Hughes, Jason D, Le, Quang T, Jamil, Ali, Bai, Yun, Ho, Nancy, Zhao, Ming, Liu, Yihui, O'Connell, Michael P et al. · 2016 · Nature Genetics
- Glioblastoma Stem Cells: Driving Resilience through ChaosBriana C. Prager, Shruti Bhargava, Vaidehi Mahadev, Christopher G. Hubert, Jeremy N. Rich · 2020 · Trends in cancer
- Critical limitations of consensus clustering in class discoveryYasin Şenbabaoğlu, George C. Michailidis, Jun Z. Li · 2014 · Scientific Reports
- Cancer stem cell heterogeneity: origin and new perspectives on CSC targetingKiyoung Eun, Seok Won Ham, Hyunggee Kim · 2017 · BMB Reports
- Tissue mechanics promote IDH1-dependent HIF1α–tenascin C feedback to regulate glioblastoma aggressionYekaterina A. Miroshnikova, Janna K. Mouw, James Matthew Barnes, Michael W. Pickup, Johnathan N. Lakins, Youngmi Kim, Khadjia A. Lobo, Anders I. Persson, Gerald F. Reis, Tracy Richmond McKnight et al. · 2016 · Nature Cell Biology
- Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneityMona Meyer, Jüri Reimand, Xiaoyang Lan, Renee Head, Xueming Zhu, Michelle M. Kushida, Jane Bayani, Jessica C. Pressey, Anath Christopher Lionel, Ian D. Clarke et al. · 2015 · Proceedings of the National Academy of Sciences
- Targeting glioma stem cells through combined BMI1 and EZH2 inhibitionXun Jin, Leo J.Y. Kim, Qiulian Wu, Lisa C. Wallace, Briana C. Prager, Tanwarat Sanvoranart, Ryan C Gimple, Xiuxing Wang, Stephen C. Mack, Tyler E. Miller et al. · 2017 · Nature Medicine
- Known and novel roles of the MET oncogene in cancer: a coherent approach to targeted therapyPaolo Maria Comoglio, Livio Trusolino, Carla Boccaccio · 2018 · Nature reviews. Cancer
- Heterogeneity of epidermal growth factor receptor signalling networks in glioblastomaFrank B. Furnari, Timothy Francis Cloughesy, Webster K. Cavenee, Paul S. Mischel · 2015 · Nature reviews. Cancer
- Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR–STAT3 signallingXinya Gao, Xin Xia, Fanying Li, Maolei Zhang, Huangkai Zhou, Xujia Wu, Jian Zhong, Zheng Zhao, Kun Zhao, Dawei Liu et al. · 2021 · Nature Cell Biology
- Trials and Tribulations of MicroRNA TherapeuticsSeyhan, Attila A. · 2024 · International Journal of Molecular Sciences
- Diagnostic, therapeutic, and prognostic implications of the 2021 World Health Organization classification of tumors of the central nervous systemSimon Gritsch, Tracy T. Batchelor, L. Nicolas Gonzalez Castro · 2021 · Cancer
- Sex differences in cancer mechanismsJoshua B. Rubin, Joseph S. Lagas, Lauren Broestl, Jasmin Sponagel, Nathan Rockwell, Gina Rhee, Sarah F. Rosen, Si Chen, Robyn S. Klein, P. I. Imoukhuede et al. · 2020 · Biology of Sex Differences
- Multiplexed Profiling of Single Extracellular VesiclesKyungheon Lee, Kyle B. Fraser, Bassel Ghaddar, Katy S. Yang, Eunha Kim, Leonora Balaj, Ennio Antonio Chiocca, Xandra O. Breakefield, Hakho Lee, Ralph Weissleder · 2017 · ACS Nano
- Pediatric high-grade glioma: biologically and clinically in need of new thinkingChris Jones, Matthias A. Karajannis, David Jones, Mark W. Kieran, Michelle Monje, Suzanne J. Baker, Oren Josh Becher, Yoon‐Jae Cho, Nalin M. Gupta, Cynthia E Hawkins et al. · 2016 · Neuro-Oncology
- Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasionEster Gangoso, Benjamin Southgate, Leanne Bradley, Stefanie Lehr, Felipe Gálvez‐Cancino, Niamh McGivern, Esra Güç, Chantriolnt-Andreas Kapourani, Adam Byron, Kirsty M. Ferguson et al. · 2021 · Cell
- Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor TypesMichael D. Iglesia, Joel S. Parker, Katherine A. Hoadley, Jonathan Stuart Serody, Charles M. Perou, Benjamin Garrett Vincent · 2016 · JNCI Journal of the National Cancer Institute
- Long Noncoding RNA NEAT1 , Regulated by the EGFR Pathway, Contributes to Glioblastoma Progression Through the WNT/ β -Catenin Pathway by Scaffolding EZH2Qun Chen, Jinquan Cai, Qixue Wang, Yunfei Wang, Mingyang Liu, Jingxuan Yang, Junhu Zhou, Chunsheng Kang, Min Li, Chuanlu Jiang · 2017 · Clinical Cancer Research
- Cell-Cycle Therapeutics Come of AgeMatthew A. Ingham, Gary K. Schwartz · 2017 · Journal of Clinical Oncology
- A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1Xin Xia, Xixi Li, Fanying Li, Xujia Wu, Maolei Zhang, Huangkai Zhou, Nunu Huang, Xuesong Yang, Feizhe Xiao, Dawei Liu et al. · 2019 · Molecular Cancer
- Mining TCGA database for genes of prognostic value in glioblastoma microenvironmentJia Di, Shenglan Li, Dali Li, Haipeng Xue, Dan Yang, Ying Liu · 2018 · Aging
- Altered cellular metabolism in gliomas — an emerging landscape of actionable co-dependency targetsJunfeng Bi, Sudhir Chowdhry, Sihan Wu, Wenjing Zhang, Kenta Masui, Paul S. Mischel · 2019 · Nature reviews. Cancer
- BRAF Inhibition in BRAF V600 -Mutant Gliomas: Results From the VE-BASKET StudyThomas Joseph Kaley, Mehdi Touat, Vivek Subbiah, Antoine Hollebecque, Jordi Ahnert Rodon, Albert Craig Lockhart, Vicki Leigh Keedy, Franck Bielle, Ralf‐Dieter Hofheinz, Florence Joly et al. · 2018 · Journal of Clinical Oncology
- The landscape of the mesenchymal signature in brain tumoursJinan Behnan, Gaetano Finocchiaro, Gabi Hanna · 2019 · Brain
- A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastomaPriya Kumthekar, Caroline H. Ko, Tatjana Paunesku, Karan Dixit, Adam M. Sonabend, Orin G. Bloch, Matthew C. Tate, Margaret A. Schwartz, Laura Zuckerman, Ray Lezon et al. · 2021 · Science Translational Medicine
- Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markersAndrey Korshunov, Marina Vladimirovna Ryzhova, Volker Hovestadt, Sebastian Bender, Dominik Sturm, David Capper, Jochen Meyer, Daniel Schrimpf, Marcel Kool, Paul A. Northcott et al. · 2015 · Acta Neuropathologica
- Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain TumorHuimin Hu, Quanhua Mu, Zhaoshi Bao, Yiyun Chen, Yanwei Liu, Jing Chen, Kuanyu Wang, Zheng Wang, Yoonhee Nam, Biaobin Jiang et al. · 2018 · Cell
- Molecular Heterogeneity and Immunosuppressive Microenvironment in GlioblastomaSyreeta DeCordova, Abhishek Shastri, Anthony George Tsolaki, Hadida Yasmin, Lukas Klein, Shiv K. Singh, Uday Kishore · 2020 · Frontiers in Immunology
- Targeting cellular pathways in glioblastoma multiformeJoshua R. D. Pearson, Tarik Regad · 2017 · Signal Transduction and Targeted Therapy
- Functional Enhancers Shape Extrachromosomal Oncogene AmplificationsAndrew R. Morton, Nergiz Dogan-Artun, Zachary J. Faber, Graham Dickson and Hugh MacLeod, Cynthia F. Bartels, Megan S. Piazza, Kevin Cameron Allan, Stephen C. Mack, Xiuxing Wang, Ryan C. Gimple et al. · 2019 · Cell
- Immunotherapy for glioblastoma: current state, challenges, and future perspectivesYang Liu, Zhou Fei, Heba A. Ali, Justin Durla Lathia, Peiwen Chen · 2024 · Cellular and Molecular Immunology
- Prognostic and Predictive Biomarkers in GliomasPaulina Śledzińska, Marek G. Bebyn, Jacek Furtak, Janusz Kowalewski, Marzena Anna Lewandowska · 2021 · International Journal of Molecular Sciences
- Epigenetics and Cancer Stem Cells: Unleashing, Hijacking, and Restricting Cellular PlasticityElanor N. Wainwright, Paola Scaffidi · 2017 · Trends in Cancer
- Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null GliomaPeiwen Chen, Di Zhao, Jun Li, Xin Liang, Jiexi Li, Andrew H. Chang, Verlene K. Henry, Zhengdao Lan, Denise J. Spring, Ganesh Rao et al. · 2019 · Cancer Cell
- Increased global transcription activity as a mechanism of replication stress in cancerPanagiotis Kotsantis, Lara Marques Silva, Sarah Irmscher, Rebecca M. Jones, Lisa K. Folkes, Natalia Gromak, Eva Petermann · 2016 · Nature Communications
- Onco-Multi-OMICS Approach: A New Frontier in Cancer ResearchSajib Chakraborty, Md. Ismail Hosen, Musaddeque Ahmed, Hossain Uddin Shekhar · 2018 · BioMed Research International
- Advances in local therapy for glioblastoma — taking the fight to the tumourThomas S. van Solinge, Lisa Nieland, Ennio Antonio Chiocca, Marike L. D. Broekman · 2022 · Nature Reviews Neurology
- The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and spaceJohanna Klughammer, Barbara Kiesel, Thomas Roetzer-Pejrimovsky, Nikolaus Fortelny, Amelie Nemc, Karl‐Heinz Nenning, Julia Furtner, Nathan C. Sheffield, Paul Datlinger, Nadine Peter et al. · 2018 · Nature Medicine
- The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular SubtypesYuan Xie, Tobias Bergström, Yiwen Jiang, Patrik Johansson, Voichita Dana Marinescu, Nanna Lindberg, Anna Segerman, Grzegorz Wicher, Mia Niklasson, Sathishkumar Baskaran et al. · 2015 · EBioMedicine
- An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain CancersGenaro R. Villa, Jonathan J. Hulce, Ciro Zanca, Junfeng Bi, Shiro Ikegami, Gabrielle L. Cahill, Yuchao Gu, Kenneth M. Lum, Kenta Masui, Huijun Yang et al. · 2016 · Cancer Cell
- MET-dependent solid tumours — molecular diagnosis and targeted therapyRobin Guo, Jia Luo, Jason C. Chang, Natasha Rekhtman, Maria E. Arcila, Alexander Edward Dela Cruz Drilon · 2020 · Nature Reviews Clinical Oncology
- Toward the Early Detection of Cancer by Decoding the Epigenetic and Environmental Fingerprints of Cell-Free DNAYmke van der Pol, Florent C. Mouliere · 2019 · Cancer Cell
- Glioblastoma Multiforme: An Overview of Emerging Therapeutic TargetsOlivia G. Taylor, Joshua S. Brzozowski, Kathryn Anne Skelding · 2019 · Frontiers in Oncology
- Diagnostic and Therapeutic Biomarkers in Glioblastoma: Current Status and Future PerspectivesWojciech Szopa, Thomas A. Burley, Gabriela Krämer-Marek, Wojciech Kaspera · 2017 · BioMed Research International
- The Role of Hypoxia in Glioblastoma InvasionAna Rita Monteiro, Richard Hill, Geoffrey John Pilkington, Patrícia A. Madureira · 2017 · Cells
- Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastomaAna C. deCarvalho, Hoon Kim, Laila Poisson, Mary E. Winn, Claudius Mueller, David Cherba, Julie M. Koeman, Sahil Seth, Alexei I. Protopopov, Michelle Madden Felicella et al. · 2018 · Nature Genetics
- Spatiotemporal Evolution of the Primary Glioblastoma GenomeJinkuk Kim, In‐Hee Lee, Hee Jin Cho, Chul‐Kee Park, Yang-Soon Jung, Yanghee Kim, So Hee Nam, Byung Sup Kim, Mark D. Johnson, Doo‐Sik Kong et al. · 2015 · Cancer Cell
- EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastomaRunping Fang, Xin Chen, Sicong Zhang, Hui Shi, Youqiong Ye, Hailing Shi, Zhongyu Zou, Peng Li, Qing Guo, Li Ma et al. · 2021 · Nature Communications
- Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneityLaura M. Richards, Owen Whitley, Graham Dickson and Hugh MacLeod, Florence M.G. Cavalli, Fiona J. Coutinho, Julia E. Jaramillo, Nataliia Svergun, Mazdak Riverin, Danielle C. Croucher, Michelle M. Kushida et al. · 2021 · Nature Cancer
- EGFR heterogeneity and implications for therapeutic intervention in glioblastomaEskil Eskilsson, Gro Vatne Røsland, Gergely Morten Solecki, Qianghu Wang, Patrick N. Harter, Grazia Graziani, Roel G.W. Verhaak, Frank Winkler, Rolf Bjerkvig, Hrvoje Miletić · 2017 · Neuro-Oncology
- Glioma CpG island methylator phenotype (G-CIMP): biological and clinical implicationsTathiane Maistro Malta, Camila Ferreira de Souza, Thaís S. Sabedot, Tiago C. Silva, Maritza S. Mosella, Steven N. Kalkanis, James Snyder, Ana Valeria B. Castro, Houtan Noushmehr · 2017 · Neuro-Oncology
- Glioblastoma at the crossroads: current understanding and future therapeutic horizonsShilpi Singh, Devanjan Dey, Debashis Barik, Iteeshree Mohapatra, Stefan Kim, Mayur Sharma, Sujata Prasad, Peize Wang, Amar Ranjan Singh, Gatikrushna Singh · 2025 · Signal Transduction and Targeted Therapy
- The NF1 somatic mutational landscape in sporadic human cancersCharlotte Philpott, Hannah Tovell, Ian M. Frayling, D.N. Cooper, Meena Upadhyaya · 2017 · Human Genomics
- Longer-term (≥ 2 years) survival in patients with glioblastoma in population-based studies pre- and post-2005: a systematic review and meta-analysisMichael T. C. Poon, Cathie L. M. Sudlow, Jonine D. Figueroa, Paul Martin Brennan · 2020 · Scientific Reports
- World Health Organization 2021 Classification of Central Nervous System Tumors and Implications for Therapy for Adult-Type GliomasTamar R. Berger, Patrick Yung Wen, Melanie Lang‐Orsini, Ugonma Nnenna Chukwueke · 2022 · JAMA Oncology
- Blood–brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapyAnna Galstyan, Janet L. Markman, Ekaterina S. Shatalova, Antonella Chiechi, Alan J. Korman, Rameshwar Patil, Dmytro Klymyshyn, Warren G. Tourtellotte, Liron Limor Israel, Oliver Braubach et al. · 2019 · Nature Communications
- Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade gliomaChris Jones, Suzanne J. Baker · 2014 · Nature reviews. Cancer
- ROS1-dependent cancers — biology, diagnostics and therapeuticsAlexander Edward Dela Cruz Drilon, Chelsea Jenkins, Sudarshan R. Iyer, Adam Jacob Schoenfeld, Clare Keddy, Monika Ashok Davare · 2020 · Nature Reviews Clinical Oncology
- Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modellingMarc Zuckermann, Volker Hovestadt, Christiane Brigitte Knobbe-Thomsen, Marc Zapatka, Paul A. Northcott, Kathrin Schramm, Jelena Belic, David Jones, Barbara R. Tschida, Branden S. Moriarity et al. · 2015 · Nature Communications
- Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio TrialThomas Sandmann, Richard Bourgon, Josep Garcia, Congfen Li, Timothy Francis Cloughesy, Olivier Louis Chinot, Wolfgang Wick, Ryo Nishikawa, Warren P. Mason, Roger Henriksson et al. · 2015 · Journal of Clinical Oncology
- Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progressionAlan T. Yeo, Shruti Rawal, Bethany Delcuze, Anthos Christofides, Agata M. P. Atayde, Laura Strauss, Leonora Balaj, Vaughn A. Rogers, Erik J. Uhlmann, Hemant Varma et al. · 2022 · Nature Immunology
- When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in GliomaSaskia Roesch, Carmen Rapp, Steffen Dettling, Christel C. Herold‐Mende · 2018 · International Journal of Molecular Sciences
- The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrenceBrenda Auffinger, Drew A. Spencer, Peter Pytel, Atique U. Ahmed, Maciej S. Lesniak · 2015 · Expert Review of Neurotherapeutics
- Metabolic reprogramming in glioblastoma: the influence of cancer metabolism on epigenetics and unanswered questionsSameer Agnihotri, Gelareh Mohammed Zadeh · 2015 · Neuro-Oncology
- <i>EGFR</i>
Variant Heterogeneity in Glioblastoma Resolved through Single-Nucleus SequencingFrancis, Joshua M., Zhang, Cheng-Zhong, Maire, Cecile L., Jung, Joonil, Manzo, Veronica E., Adalsteinsson, Viktor A., Homer, Heather, Haidar, Sam, Blumenstiel, Brendan, Pedamallu, Chandra Sekhar et al. · 2014 · Cancer Discovery
- Detection, Characterization, and Inhibition of FGFR–TACC Fusions in IDH Wild-type GliomaAnna Luisa Di Stefano, Alessandra Fucci, Veroniquè Frattini, Marianne Labussière, Karima Mokhtari, Pietro Zoppoli, Yannick Marie, Aurélie Bruno, Blandine Boisselier, Marine Giry et al. · 2015 · Clinical Cancer Research
- Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein responseSabine Hombach‐Klonisch, Maryam Mehrpour, Shahla Shojaei, Craig Henry Harlos, Marshall W. Pitz, Ahmed Hamaï, Krzysztof Siemianowicz, Wirginia Likus, Emilia Wiecheć, Brian D. Toyota et al. · 2017 · Pharmacology & Therapeutics
- Prognostic relevance of genetic alterations in diffuse lower-grade gliomasAoki, Kosuke, Nakamura, Hideo, Suzuki, Hiromichi, Matsuo, Keitaro, Kataoka, Keisuke, Shimamura, Teppei, Motomura, Kazuya, Ohka, Fumiharu, Shiina, Satoshi, Yamamoto, Takashi et al. · 2018 · Neuro-Oncology
- BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade GliomaMatthew Mistry, Nataliya Zhukova, Daniele Merico, Patricia Rakopoulos, Rahul Krishnatry, Mary Shago, James Stavropoulos, Noa Alon, Jason D. Pole, Peter N. Ray et al. · 2015 · Journal of Clinical Oncology
- Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor typesNils Johan Fredriksson, Lars Ny, Jonas A. Nilsson, Erik Larsson · 2014 · Nature Genetics
- Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant ProgressionWang, Xiuxing, Prager, Briana C., Wu, Qiulian, Kim, Leo J.Y., Gimple, Ryan C., Shi, Yu, Yang, Kailin, Morton, Andrew R., Zhou, Wenchao, Zhu, Zhe et al. · 2018 · Cell Stem Cell
- Targeting Glioblastoma Stem Cells through Disruption of the Circadian ClockZhen Dong, Guoxin Zhang, Meng Qu, Ryan C. Gimple, Qiulian Wu, Zhixin Qiu, Briana C. Prager, Xiuxing Wang, Leo J.Y. Kim, Andrew R. Morton et al. · 2019 · Cancer Discovery
- Isocitrate dehydrogenase mutations in gliomasMatthew S. Waitkus, Bill H. Diplas, Hai Yan · 2015 · Neuro-Oncology
- Glioblastoma multiforme: insights into pathogenesis, key signaling pathways, and therapeutic strategiesAshkan Pouyan, Masoud Ghorbanlo, Masoud Eslami, Majid Jahanshahi, Ehsan Ziaei, Ali Salami, Khatere Mokhtari, Koorosh Shahpasand, Najma Farahani, Tohid Emami Meybodi et al. · 2025 · Molecular Cancer
- Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA VariantsBryan D. Smith, Michael D. Kaufman, Wei-Ping Lu, Anu Gupta, Cynthia B. Leary, Scott Wise, Thomas J. Rutkoski, Yu Mi Ahn, Gada Al-Ani, Stacie L. Bulfer et al. · 2019 · Cancer Cell
- Spatiotemporal genomic architecture informs precision oncology in glioblastomaJin‐Ku Lee, Jiguang Wang, Jason K. Sa, Erik Ladewig, Hae‐Ock Lee, In‐Hee Lee, Hyun Ju Kang, Daniel I. S. Rosenbloom, Pablo G. Cámara, Zhaoqi Liu et al. · 2017 · Nature Genetics
- Pathological and Molecular Features of Glioblastoma and Its Peritumoral TissueAlessio D’Alessio, Gabriella Proietti, Gigliola Sica, Bianca Maria Scicchitano · 2019 · Cancers
- Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive GrowthBaoli Hu, Qianghu Wang, Yanru Wang, Sujun Hua, Charles-Etienne Gabriel Sauvé, Derrick Sek Tong Ong, Zheng D. Lan, Qing Chang, Yan Wing Ho, Marta Moreno Monasterio et al. · 2016 · Cell
- Dendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell–driven rejection of high-grade gliomaGarg, Abhishek D., Vandenberk, Lien, Koks, Carolien, Verschuere, Tina, Boon, Louis, Van Gool, Stefaan W., Agostinis, Patrizia · 2016 · Science Translational Medicine
- Transcriptome analysis reveals tumor microenvironment changes in glioblastomaHoogstrate, Youri, Draaisma, Kaspar, Ghisai, Santoesha A., van Hijfte, Levi, Barin, Nastaran, de Heer, Iris, Coppieters, Wouter, van den Bosch, Thierry P.P., Bolleboom, Anne, Gao, Zhenyu et al. · 2023 · Cancer Cell
- Molecular Mechanisms of Treatment Resistance in GlioblastomaAlexander C. Ou, W.K. Alfred Yung, Nazanin Majd · 2020 · International Journal of Molecular Sciences